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Built-In Backup System Helps Muscles Counteract Fatigue
When you're running up stairs or out on a jog, your muscles eventually start to feel heavy and weak. That's fatigue setting in, a sign that the muscles’ energy reserves are becoming depleted. But a team of researchers led by Rensselaer Polytechnic Institute (RPI) biology professor Doug Swank, Ph.D., have discovered something surprising: certain muscle fibers have a built-in backup system that fights back against fatigue, potentially helping us keep going when we'd otherwise have to stop. The secret lies in a phenomenon called "stretch activation": when a muscle is stretched just before it contracts, it can produce a short burst of extra force. Stretch activation has been studied extensively in the context of insect flight muscle and heart muscle contraction in mammals, but its effects have long been assumed to be physiologically irrelevant for the big skeletal muscles we use for day-to-day activities like walking around. The new study, published in the Journal of General Physiology, shows that assumption was wrong, at least when it comes to certain fast-twitch muscle fibers used to produce quick, powerful movements. “For decades, stretch activation in skeletal muscle was considered physiologically insignificant because it contributes a relatively small amount of force under normal conditions," Swank said. "But we realized no one had tested what happens during fatigue, when the chemical environment inside muscle fibers changes significantly." The researchers tested individual muscle fibers from mice under three conditions: normal, early fatigue (with chemical changes that mimic the state of tired muscles), and severe fatigue. They found that while the fibers' normal force production dropped dramatically as expected, in certain fibers the stretch-activated force stayed the same or even increased. In the most fatigued state, stretch activation contributed up to 30% of the total force these fast-twitch fibers were generating. “What was dismissed as too small to matter may actually be an important fatigue-fighting mechanism that's been hiding in plain sight,” Swank said. The effect was specific to fast-twitch fibers, which are used to generate rapid, powerful movements like sprinting and jumping. Slow-twitch fibers, which are used during endurance tasks like long-distance running or cycling, are more fatigue-resistant to begin with, and showed almost no stretch activation response. Understanding how muscles naturally combat fatigue could eventually inform strategies for improving strength and endurance, whether for athletes, people with muscular disorders, or patients recovering from injury. Swank and his colleagues are following up on their findings by conducting more detailed explorations of how stretch activation contributes to force generation in both low-intensity and high-intensity exercise. The research is funded by a five-year, $2.7 million National Institutes of Health grant to Professor Swank.

Gates Foundation to Fund RPI Research to Develop Low-Cost Monoclonal Antibody Treatments
Professor Todd Przybycien, Ph.D., head of RPI’s Department of Chemical and Biological Engineering, has been awarded a $3.1 million share of a Gates Foundation Global Grand Challenge grant to advance exceptionally low-cost monoclonal antibody (mAb) manufacturing. Monoclonal antibodies have proven effective at treating a wide range of conditions, including infectious diseases like COVID-19, autoimmune disorders, and certain types of cancer. But they are expensive to produce, and current market prices of $50 to $100 per gram put them effectively out-of-reach for millions of people around the world. The goal of the Gates Grand Challenge is to reduce the price of mAbs to just $10 per gram. Last month, the Gates Foundation announced $10.5 million in funding to a team led by the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) in order to achieve that goal. Professor Przybycien’s group is part of that team and will focus on improving the process of purifying monoclonal antibodies after they have been produced by engineered cells. “Optimization and intensification of the downstream purification process offer the exciting possibility of breaking through to the $10/g overall target,” Przybycien said. “We are excited to advance the precipitation-based process we have developed with our collaborator at Penn State as part of the manufacturing solution to sustainably meet the global need for monoclonal antibodies.” Przybycien is an internationally recognized researcher in biomanufacturing and applied biophysics, focusing on developing processes to manufacture recombinant proteins, mRNA, and viral vectors. He has won numerous awards including the NSF CAREER Award and the Camille Dreyfus Teacher-Scholar Award. He is also a fellow of the American Chemical Society, AIChE, and AIMBE. “This grant is a testament to the years of work Todd Przybycien and his team have done to optimize and improve biopharmaceutical manufacturing processes,” said Shekhar Garde, Ph.D., the Thomas R. Farino, Jr. ’67 and Patricia E. Farino Dean of the School of Engineering. “It will pave the way for affordable access to lifesaving medications for millions of people who desperately need them.” “We are excited by the opportunity to demonstrate that there are existing solutions developed by industry and academic partners that can significantly reduce cost of goods and accelerate timelines,” said Kelvin Lee, NIIMBL Institute Director. “We are honored to receive this grant from the Gates Foundation, which will enable this exceptional team to deliver meaningful advances to antibody production efficiency.” This Gates Grand Challenge was established in honor of Dr. Steve Hadley, who championed the reduction of mAbs costs to make them affordable in low- and middle-income countries. The team’s first target will be a monoclonal antibody to treat malaria, an infectious disease which kills more than half a million people each year, primarily in Africa.

The National Cancer Institute (NCI) has renewed the Cancer Center Support Grant (CCSG) for The Wistar Institute and ChristianaCare’s Helen F. Graham Cancer Center & Research Institute, awarding $16.3 million over the next five years. The renewal received an “exceptional” rating — the highest possible — recognizing the strength and impact of a partnership that combines world-class basic science with leading community-based cancer care. A One-of-a-Kind National Model This collaboration is the only one of its kind in the nation, joining Wistar, an NCI-Designated Basic Cancer Center, with ChristianaCare, one of the country’s premier academic community cancer centers and a National Cancer Institute Community Oncology Research Program. Together, they focus on driving advances against some of the most challenging cancers, including pancreatic, melanoma, breast, lung and ovarian cancers. The grant supports shared infrastructure, scientific resources and programs that enable researchers and clinicians to work seamlessly across both institutions. By connecting laboratory breakthroughs at Wistar with ChristianaCare’s ability to rapidly apply new approaches in a diverse patient population, the partnership accelerates the path from discovery to care. NCI highlighted the collaboration’s effectiveness, noting that “the ongoing alliance with the Helen F. Graham Cancer Center & Research Institute is where most clinical translation into active oncology trials is occurring, supported by productive collaboration between Wistar investigators and Graham Cancer Center oncologists.” Impact on Patients and Community “At ChristianaCare, we are committed to bringing innovation directly to the people we serve. Our collaboration with Wistar connects the best of basic science with the realities of patient care,” said Thomas Schwaab, M.D., Ph.D., Bank of America Endowed Medical Director of the Helen F. Graham Cancer Center & Research Institute. “The NCI’s exceptional score recognizes the promise of this work and the progress we are making together. It is a powerful affirmation that our patients are benefiting from research at the highest level.” “This renewal from the NCI is proof that we are building a model for how cancer research and community care can come together,” said Nicholas J. Petrelli, M.D., director of the Cawley Center for Translational Cancer Research at the Helen F. Graham Cancer Center & Research Institute and associate director of Translational Research at The Wistar Institute Cancer Center. “Through our partnership with Wistar, patients in Delaware and beyond are gaining access to cutting-edge research and therapies for some of the toughest cancers we face.” Dario Altieri, M.D., president and CEO of The Wistar Institute and director of its Ellen and Ronald Caplan Cancer Center, added: “An exceptional rating from the NCI is a reflection of the scientific excellence and real-world impact of this partnership. What makes this collaboration unique is its ability to take discoveries in areas such as melanoma and ovarian cancer and bring them rapidly into clinical practice through ChristianaCare.” NCI underscored the alliance’s reach, noting that “the partnership with the Graham Cancer Center brought cutting-edge cancer research to the community and advanced groundbreaking discoveries to first-in-human oncology clinical trials.” A Pipeline of Research Advancing Faster Than Ever Research achievements supported by the Wistar—ChristianaCare partnership include: Advancing multiple Wistar discoveries into investigator-initiated, first-in-human oncology clinical trials, including studies in pancreatic, melanoma, lung, breast and ovarian cancers. Launching joint research programs across several cancer types, with expanding efforts in cancer risk and population health. Increasing access to high-quality biospecimens — including tumor tissue, biopsies and blood samples — that fuel translational research. Strengthening shared scientific infrastructure supporting immunotherapy research, organoid development, xenograft models and molecular profiling. The Wistar—ChristianaCare partnership, established in 2011, has grown into a nationally recognized alliance that bridges science and medicine. With this CCSG renewal, the collaboration will expand research in pancreatic, melanoma, breast, lung and ovarian cancers and continue advancing prevention, early detection and training programs for the next generation of physician—scientists. The Helen F. Graham Cancer Center & Research Institute depends on grants and community support to keep this work moving forward. To learn more or make a gift, visit Support the Helen F. Graham Cancer Center & Research Institute.

Violence alters human genomes for generations, researchers discover
In February of 1982, the Syrian government besieged the city of Hama, killing tens of thousands of its own citizens in sectarian violence. Four decades later, rebels used the memory of the massacre to help inspire the toppling of the Assad family that had overseen the operation. But there is another lasting effect of the attack, hidden deep in the genes of Syrian families. The grandchildren of women who were pregnant during the siege — grandchildren who never experienced such violence themselves — nonetheless bear marks of it in their genomes. Passed down through their mothers, this genetic imprint offers the first human evidence of a phenomenon previously documented only in animal models. The genetic transmission of stress across multiple generations. “The idea that trauma and violence can have repercussions into future generations should help people be more empathetic, help policymakers pay more attention to the problem of violence,” said Connie Mulligan, Ph.D., a professor of Anthropology and the Genetics Institute at the University of Florida and co-senior author of the new study. “It could even help explain some of the seemingly unbreakable intergenerational cycles of abuse and poverty and trauma that we see around the world, including in the U.S.” While our genes are not changed by life experiences, they can be tuned through a system known as epigenetics. In response to stress or other events, our cells can add small chemical flags to genes that may quiet them down or alter their behavior. These changes may help us adapt to stressful environments, although the effects aren’t well understood. It is these tell-tale chemical flags that Mulligan and her team were looking for in the genes of Syrian families. While lab experiments have shown that animals can pass along epigenetic signatures of stress to future generations, proving the same in people has been nearly impossible. “Resilience and perseverance is quite possibly a uniquely human trait.” —Connie Mulligan Mulligan worked with Rana Dajani, Ph.D., a molecular biologist at Hashemite University in Jordan and co-senior author, as well as anthropologist Catherine Panter-Brick, Ph.D., of Yale University, to conduct the unique study. Dajani envisioned the research project; because of her intimate knowledge of the Syrian population and its tragic history, she designed the study to cover three generations of Syrian refugees to Jordan. Some families had lived through the Hama attack before fleeing to Jordan. Other families avoided Hama, but lived through the recent civil war against the Assad regime. The team collected samples from grandmothers and mothers who were pregnant during the two conflicts, as well as from their children. This study design meant there were grandmothers, mothers and children who had each experienced violence at different stages of development. A third group of families had immigrated to Jordan before 1980, avoiding the decades of violence in Syria. These early immigrants served as a crucial control to compare to the families who had experienced the stress of civil war. Study coauthor Dima Hamadmad, a Syrian researcher and the daughter of refugees, led the search for families that met the study criteria and collected cheek swabs from 138 people across 48 families. "The participants took part in the research out of love for their children and concern for future generations,” she said. “But more than that, they wanted their stories of trauma to be heard and acknowledged.” Back in Florida, Mulligan’s lab scanned the DNA for epigenetic modifications and looked for any relationship with the families’ experience of violence. In the grandchildren of Hama survivors, the researchers discovered 14 areas in the genome that had been modified in response to the violence their grandmothers experienced. These 14 modifications demonstrate that stress-induced epigenetic changes may indeed appear in future generations in humans, just as they can in animals. The study also uncovered 21 epigenetic sites in the genomes of people who had directly experienced violence in Syria. In a third finding, the researchers reported that people exposed to violence while in their mothers’ wombs showed evidence of accelerated epigenetic aging, a type of biological aging that may be associated with susceptibility to age-related diseases. Most of these epigenetic changes showed the same pattern after exposure to violence, suggesting a kind of common epigenetic response to stress – one that can not only affect people directly exposed to stress, but also future generations. “We think our work is relevant to many forms of violence, not just refugees. Domestic violence, sexual violence, gun violence: all the different kinds of violence we have in the U.S,” said Mulligan. “We should study the effects of violence. We should take it more seriously.” It’s not clear what, if any, effect these epigenetic changes have in the lives of people carrying them inside their genomes. But some studies have found a link between stress-induced epigenetic changes and diseases like diabetes. One famous study of Dutch survivors of famine during World War II suggested that their offspring carried epigenetic changes that increased their odds of being overweight later in life. While many of these modifications likely have no effect, It’s possible that some have functional effects that can affect our health, Mulligan said. The researchers published their findings, which were supported by the National Science Foundation, Feb. 27 in the journal Scientific Reports. While carefully searching for evidence of the lasting effects of war and trauma stamped into our genomes, Mulligan and her collaborators were also struck by the perseverance of the families they worked with. Their story was much bigger than merely surviving war, Mulligan said. “In the midst of all this violence we can still celebrate their extraordinary resilience. They have persevered,” Mulligan said. “That resilience and perseverance is quite possibly a uniquely human trait.”

The School of Science at Rensselaer Polytechnic Institute (RPI) has launched a new minor in quantum computing, positioning students at the forefront of one of the most rapidly developing fields in technology. The minor leverages RPI's unique status as the first university in the world to house an IBM Quantum System One on campus, providing students with unprecedented access to utility-scale quantum computing technology. The minor, which is now available to all currently enrolled students, requires four courses drawn from physics, computer science, mathematics, and engineering. The curriculum provides both theoretical foundations and practical exposure to quantum hardware and software, and gives students a leg up in a field rapidly approaching quantum advantage — the point at which quantum systems outperform classical computing approaches on meaningful tasks. "The quantum computing minor will augment the training of RPI students with insight into an emerging technology that will reshape industries from pharmaceuticals to artificial intelligence," said Steven Tait, Ph.D., Dean of the School of Science. "With direct access to the IBM Quantum System One, our students will gain hands-on experience with cutting-edge tools that are not yet widely available. This minor equips them with the interdisciplinary foundation needed to understand and contribute to quantum-enabled innovation." The minor arrives at a pivotal moment in quantum computing's evolution. IBM's demonstration of quantum utility in 2023 marked the beginning of an era in which quantum systems serve as scientific tools to explore complex problems in chemistry, physics, and materials science — areas where quantum advantage offers transformative potential. Hannah Xiuying Fried, graduating this December, is one of the first students to declare the minor. “I'm not a physics or computer science major, so it allows me an accredited way to prove a relevant background to future employers,” she said. “It prepares me for graduate school where I plan to continue pursuing quantum hardware research.” Currently enrolled students may declare the minor now and pursue it alongside their established degree programs. Interested students should contact Chad Christensen at sciencehub@rpi.edu.

Dinosaurs in New Mexico Thrived Until the Very End, Study Shows
For decades, many scientists believed dinosaurs were already dwindling in number and variety long before an asteroid strike sealed their fate 66 million years ago. But new research in the journal Science from Baylor University, New Mexico State University, the Smithsonian Institution and an international team is rewriting that story. The dinosaurs, it turns out, were not fading away. They were flourishing. A final flourish in the San Juan Basin In northwestern New Mexico, layers of rock preserve a hidden chapter of Earth’s history. In the Naashoibito Member of the Kirtland Formation, researchers uncovered evidence of vibrant dinosaur ecosystems that thrived until just before the asteroid impact. High-precision dating techniques revealed that fossils from these rocks are between 66.4 and 66 million years old – placing them in the catastrophic Cretaceous-Paleogene boundary. “The Naashoibito dinosaurs lived at the same time as the famous Hell Creek species in Montana and the Dakotas... They were not in decline – these were vibrant, diverse communities.” – Daniel Peppe, Ph.D. “The Naashoibito dinosaurs lived at the same time as the famous Hell Creek species in Montana and the Dakotas,” said Daniel Peppe, Ph.D., associate professor of geosciences at Baylor University. “They were not in decline – these were vibrant, diverse communities.” Dinosaurs in their prime The New Mexico fossils tell a different story than originally thought. Far from being uniform and weakened, dinosaur communities across North America were regionally distinct and thriving. Using ecological and biogeographic analyses, the researchers discovered that dinosaurs in western North America lived in separate “bioprovinces,” divided not by mountains or rivers, but by temperature differences across regions. “What our new research shows is that dinosaurs are not on their way out going into the mass extinction,” said first author Andrew Flynn, Ph.D., ‘20, assistant professor of geological sciences at New Mexico State University. “They're doing great, they're thriving and that the asteroid impact seems to knock them out. This counters a long-held idea that there was this long-term decline in dinosaur diversity leading up to the mass extinction making them more prone to extinction.” Life after impact The asteroid impact ended the age of dinosaurs in an instant – but the ecosystems they left behind set the stage for what came next, the researchers said. Within 300,000 years of their extinction, mammals began to diversify rapidly, exploring new diets, body sizes and ecological roles. The same temperature-driven patterns that shaped dinosaur communities continued into the Paleocene, showing how climate guided life’s rebound after catastrophe. “The surviving mammals still retain the same north and south bio provinces,” Flynn said. “Mammals in the north and the south are very different from each other, which is different than other mass extinctions where it seems to be much more uniform.” Why the discovery matters today The discovery is more than a window into the past – it’s a reminder of the resilience and vulnerability of life on Earth. Conducted on public lands managed by the U.S. Bureau of Land Management, the research highlights how carefully protected landscapes can yield profound insights into how ecosystems respond to sudden global change. With a clearer understanding of the timeline of the dinosaurs’ final days, the study reveals not a slow fade into extinction but a dramatic ending to a story of flourishing diversity cut short by cosmic chance.
A Roadmap or a Rift? Examining Trump’s 28-Point Ukraine Peace Proposal
As negotiations around the war in Ukraine continue to dominate global headlines, a newly surfaced 28-point peace proposal associated with former U.S. President Donald Trump has triggered intense debate across NATO capitals, Kyiv, and Moscow. The document — described in reporting by Reuters, Axios, Sky News, Al Jazeera and other outlets — outlines a framework aimed at ending the conflict but includes provisions that many analysts say could significantly reshape Europe’s security landscape. A Plan Built Around Ceasefire, Guarantees, and Reconstruction At its core, the plan calls for a formal ceasefire, a non-aggression pact between Russia, Ukraine, and European states, and a set of “security guarantees” meant to deter future conflict. Reporting indicates that Ukraine would receive assurances that any renewed Russian offensive would trigger a coordinated international response. The plan also proposes the creation of a major reconstruction program — potentially financed in part with frozen Russian assets — to rebuild infrastructure and modernize Ukraine’s economy. The proposal references pathways for deeper Ukrainian integration with Europe, including support for progressing toward EU membership and providing enhanced access to European markets. A large “Ukraine Development Fund” is also mentioned in multiple summaries of the plan. Provisions Driving the Most Global Pushback The most controversial elements relate to Ukraine’s territorial integrity and long-term security posture. Outlets such as Sky News and Al Jazeera report that the draft would recognize Russian control over Crimea and large parts of Donetsk, Luhansk, Zaporizhzhia, and Kherson — areas currently occupied by Russian forces. Ukraine would also be required to formally abandon NATO membership and cap its military at 600,000 personnel. Additional provisions include restrictions on the presence of foreign troops in Ukraine, phased lifting of sanctions on Russia, full amnesty for war-related actions, and the reintegration of Russia into global economic and political structures. These components have drawn sharp responses, particularly from European leaders who argue the plan could reward aggression and undermine international legal norms. Dr. Glen Duerr is a citizen of three countries. He was born in the United Kingdom, moved to Canada as a teenager, and then to the United States to obtain his Ph.D. His teaching and research interests include nationalism and secession, comparative politics, international relations theory, sports and politics, and Christianity and politics. View his profile. What Remains Unclear or Still Under Discussion Reporting from Reuters and AP notes that many sections of the plan remain undefined or are still in flux. The exact mechanism behind the proposed security guarantees is not detailed. Oversight of reconstruction funds, timelines for reintegration of Russia, and the legal handling of frozen assets also require further clarification. Some reporting suggests parts of the plan draw from a prior informal Russian “non-paper,” raising questions about the provenance and intent of specific provisions. Why the Proposal Matters With the war approaching four years of fighting, any formal proposal for ending hostilities carries significant geopolitical weight. Supporters of the plan frame it as a pragmatic attempt to halt loss of life and begin rebuilding. Critics argue it risks legitimizing territorial conquest and weakening the broader post-Cold-War security order. As governments evaluate the implications, journalists covering defense, diplomacy, and international law will find this evolving proposal central to understanding where U.S., European, Russian, and Ukrainian negotiators may — or may not — be willing to go next.

Giving with Purpose This Holiday Season
As the season of giving draws near, many people are searching for meaningful ways to support the causes that matter most. From local food banks to global humanitarian organizations, charitable giving offers an opportunity to make a genuine difference – for the organization and for the donor. Two Baylor University experts in consumer behavior and philanthropy – James A. Roberts, Ph.D., The Ben H. Williams Professor of Marketing in the Hankamer School of Business, and Andrew P. Hogue, Ph.D., associate dean in the Office of Engaged Learning and founder of Philanthropy and the Public Good program – share five practical strategies to help donors give with intention and impact. Five ways to give more thoughtfully and effectively 1. Choose a cause that resonates with you Begin by considering the issues that matter most –education, hunger, health care, the environment or another area close to your heart. Once you identify your passion, take time to research organizations working in that space. Look for transparency, measurable results and a strong record of directing funds to mission-focused programs. “A helpful shortcut is to see whether a nonprofit receives repeat grants from charitable foundations,” Hogue said. “Those grants typically follow a rigorous evaluation process.” 2. Decide what you can comfortably give Giving should feel fulfilling, not stressful. Roberts and Hogue recommend reviewing your household budget and determining an amount that fits comfortably. Even small donations can accumulate into meaningful support over time. 3. Consider how often you want to give Think about whether a single contribution or ongoing support works best for you. Regular giving helps nonprofits plan ahead and maintain steady programming. “Consistent donations allow charities to allocate resources more effectively throughout the year,” Hogue said. 4. Automate your contributions Setting up recurring gifts through your bank or directly with a nonprofit keeps your generosity on track with minimal effort. Automatic withdrawals ensure reliability for the organization and ease for the donor. “It’s a simple way to make sure you don’t forget to give,” Roberts said, “and it provides charities with predictable support.” 5. Offer your time and talent if money is tight Financial support is just one form of generosity. Time, skills and personal networks can be equally valuable. “Donating your time and skills can be just as impactful,” Roberts said. “Whether you’re mentoring, sorting donations or helping at events, your presence matters.” Hogue added that giving enriches both the recipient and the giver: “Charitable giving is about making a difference in others’ lives while adding purpose and connection to your own.” His advice: start small, stay consistent and simply take the first step. “Giving is deeply rewarding,” Hogue said. “And as you grow in your generosity, keep a beginner’s mindset – there is always room to improve how we steward the resources entrusted to us.” Looking to know more or arrange an interview? Simply click on the expert's icon below or contact: Shelby Cefaratti-Bertin today.

Nandi A. Marshall, DrPH, professor and associate dean for Georgia Southern University’s Jiann-Ping Hsu College of Public Health, has been named president of the American Public Health Association (APHA), the nation’s oldest and largest organization of public health professionals. Marshall began her presidential term on Nov. 5, following a year as president-elect. She will serve a three-year term on APHA’s executive board, including her current presidential year and a subsequent year as immediate past president. With more than two decades of experience in community-engaged public health, Marshall is widely recognized for her leadership in advancing maternal and child health equity, and for her dedication to preparing the next generation of the public health workforce. She holds a bachelor’s in religious studies from Spelman College, a master’s in public health from East Stroudsburg University and a Doctor of Public Health from Georgia Southern. “Dr. Marshall’s appointment to lead APHA is a tremendous national recognition of her contribution to public health — and a reflection of Georgia Southern’s growing impact on the global public health landscape,” said Avinandan Mukherjee, Ph.D., provost and executive vice president for Academic Affairs. “Her commitment to community partnership, workforce development and health equity exemplifies the values we strive to instill in every graduate of our distinctive public health college.” Marshall’s work has centered on bridging lived experience and scientific research to drive equitable health outcomes. “I’m deeply honored to serve as APHA president,” Marshall said. “Public health calls us to listen to communities, honor their wisdom and work together to build the equitable systems that recognize health as a human right. Equity is not an outcome — it’s a commitment. And I’m grateful to continue this work with purpose, courage and love alongside partners across the country.” Founded in 1872, APHA represents more than 25,000 members nationwide, serving as a convener, catalyst and advocate for equitable health and well-being for all. The association connects practitioners, researchers, educators and policymakers to advance evidence-based public health initiatives. Looking to know more about Georgia Southern University or connect with Dr. Marshall — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.

One AI-based advancement at a time, UF leaders are transforming the sports industry
As emerging technologies like AI reshape sport industries and professional demands evolve, it is essential for students to graduate with the expertise to thrive in their future careers. To ensure that these students are set up for success, the UF College of Health & Human Performance has launched a new sports analytics program. Led by Scott Nestler, Ph.D., CAP, PStat, a professor of practice in the Department of Sport Management and a national analytics and data science expert, the program ties back to the UF & Sport Collaborative – a five-part project intended to elevate UF’s presence on the global stage in sports performance, healthcare and communication. “Tools and insights that previously were only available to professional sports teams are now coming to the college level, and it makes sense for universities to begin using these data, technologies and new analytic methods,” Nestler said. The sports analytics program fosters collaboration between academic units, such as the Warrington College of Business and the University Athletic Association, helping bridge the gap between sport research and innovation and empowering students to address real-world challenges through data and AI. For example, the program offers opportunities to leverage technology and analytics for strategic decision making in player acquisition, team formation and in-game decisions. Beyond performance metrics, the program also explores marketing strategies and revenue analytics, providing a well-rounded understanding of the field. “When you have enough data and a large enough sample of individuals, AI can help make predictions that otherwise would take prohibitively longer for a human to accomplish with traditional methods,” said Garrett Beatty, Ph.D., the assistant dean for innovation and entrepreneurship and an instructional associate professor in the College of Health & Human Performance’s Department of Applied Physiology and Kinesiology. “Because those data volumes are getting so large, AI models, machine learning, deep learning and other strategies can be leveraged to make sense and glean insights from sport and human performance data in ways that have never been done before.” The program seeks to offer several educational opportunities, such as individual courses, certificate programs and potentially a full degree program. In the long term, Nestler envisions the program evolving into a center or institute, beginning with establishing a research lab in the spring. Additionally, the program will leverage the university’s supercomputer, HiPerGator, to analyze larger data sets and use newer predictive modeling machine learning algorithms. “As faculty and staff move from working with box score and play-by-play data to using tracking data, which contains coordinates of all players and the ball on the field or court tens of times per second, the size of data files in sports analytics has grown tremendously,” Nestler said. “HiPerGator, with its large storage capacity and multiple central processing units/graphic processing units, is ideal for using in sports analytics work in 2025.” Nestler also aims to increase student involvement by enhancing UF’s Sport Analytics Club and hiring research assistants to work on projects for the University Athletic Association. “We need to take a broader view of what AI is and realize that it incorporates a lot of what we’ve been calling data science and analytics in the form of machine learning models, which came more out of statistics and computer science. Those are types of AI and those that I think will largely continue to be used in the coming years within the sports space,” Nestler said. “Also, we’re continuing to see growth in the number of people interested in working in this space, and I don’t foresee that changing. Fortunately, we are also seeing the number of opportunities available to those with the appropriate skills increase as well.”






