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Researchers are exploring new ways to ‘listen’ to and record electrical signals emitted from brain cells Findings could be used to help treat conditions like epilepsy and schizophrenia Project will use newly developed nanomaterials to keep removed samples of brain healthy for longer to allow more understanding of what generates epileptic seizures. A new method of examining the brain’s electrical signals could hold the key to better treatment and understanding of conditions like epilepsy and schizophrenia. Researchers at Aston University are exploring new ways to ‘listen’ to and record electrical signals emitted from brain cells, which could be used to help treat the conditions. Dr Petro Lutsyk, lecturer in electronic engineering and systems in the College of Engineering and Physical Sciences and member of Aston Institute of Photonic Technologies (AIPT), together with Dr Stuart Greenhill, senior lecturer in neuroscience in the College of Health and Life Sciences and member of Aston Institute of Health and Neurodevelopment (IHN), have been awarded £100,000 by the Royal Society to conduct the project Nanomaterial Webs for Revolutionary Brain Recording. Currently, epilepsy patients who can’t be helped by drugs may undergo brain surgery in order to prevent seizures, removing the part of the brain that is the ‘focus’ of the seizures. Dr Greenhill said: “The research project will use newly developed nanomaterials to keep samples of brain healthy and active for far longer than current technology allows, whilst recording the activity of the tissue. “This allows more understanding of what generates epileptic seizures and opens up new avenues for drug development, meaning fewer surgeries may be needed in the future. “Eventually, the technology may lead to new and better ways of recording from patients’ brains before surgery.” The two-year project will see materials and electronic engineering applied to translational neuroscience research. The grant is from the Royal Society APEX Awards scheme (Academies Partnership in Supporting Excellence in Cross-disciplinary research award) which offers researchers with a strong track record in their area an opportunity to pursue interdisciplinary research to benefit wider society. For more information about studying at Aston University please visit our website.
Aston University and Partnership Medical shortlisted for knowledge transfer partnership award
Aston University and Partnership Medical (PML) have been shortlisted for an award at the KTP Awards 2022. The partnership has been shortlisted in the category of Best Knowledge Transfer Partnership for its work on a revolutionary automated cleaning system which uses synthetic chemistry to sterilise endoscopes, reducing risks of contamination to patients and lowering rates of mortality. A knowledge transfer partnership (KTP) is a three-way collaboration between a business, an academic partner and a highly qualified researcher , known as a KTP associate. The UK-wide programme helps businesses to improve their competitiveness and productivity through the better use of knowledge, technology and skills. Aston University is the leading KTP provider within the Midlands. The KTP Awards recognise the people and partnerships behind the UK’s most inspiring and successful KTP projects. At present there are more than 800 inspiring collaborations happening across the country. Endoscopes are long, thin tubes with a light and camera at one end. Due to the sensitivity of the materials and electronics they cannot be sterilised, opening up high potential for cross infection. Through their automated cleaning system, Aston University and PML achieved industry-leading levels of disinfection, reducing risks of contamination to patients and lowering rates of mortality. The automated prototype and new cleaning materials developed in the KTP produced astonishing results in clinical trials, with a simple five-minute treatment offering deep cleaning levels 1,000 times better than anticipated, providing hygiene levels far superior to those currently possible using conventional manual procedures Mark Smith, executive director of business and regional engagement at Aston University, said: "It’s truly wonderful that Aston University has been formally recognised as a sector leader for knowledge transfer programmes, reflecting the scale and quality of our work with business. Making the shortlist is a recognition of our continued growth and sustained achievements in the knowledge exchange area. “The Aston University and Partnership Medical project has resulted in a far more effective medical cleaning system that ensures that endoscopes are truly sterile, which will ultimately save lives. This is just one example of the University’s real-world support for businesses and their customers. “It is an honour to be considered for best KTP at such a prestigious event, especially when knowledge exchange activity is at a high, with over 800 collaborations happening across the UK.” Partnership Medical Ltd (PML), based in Stoke-on-Trent, are specialists in supplying cleaning equipment and consumables for flexible endoscopes with over 20 years of distributor experience. The company aims to become a leading manufacturer/provider for endoscopic departments in clinics and hospitals worldwide. The Aston University team who worked on the KTP included Dr Andy Sutherland, reader in organic chemistry and member of the Aston Institute of Materials Research, Dr Tony Worthington, associate professor in clinical microbiology and infectious diseases and member of the Biosciences Research Group together with KTP associate, Dr Thien Duong, an expert in synthetic chemistry. The awards ceremony will take place on Wednesday 12 October in Liverpool and will be streamed online for those unable to attend in person.
Aston University history department gears up for live talk to mark 75 years since Indian partition
75 Years On: The Partition of India in a Global Perspective will take place at Café Artum at Hockley Social Club in Birmingham The partition saw the British Indian Empire split into two independent dominions, India and Pakistan The event on 25 August is the second in the series of Society matters LIVE. Aston University’s history department is set to host a live talk to mark 75 years since Indian partition. 75 Years On: The Partition of India in a Global Perspective will take place at Café Artum in Hockley Social Club on Thursday 25 August from 1700 to 1900 hrs. The event on 25 August is the second in the series of Society matters LIVE. The British decision in June 1947 to grant independence to its colony by creating two separate states caused the displacement of over ten million people as well as hundreds of thousands of casualties. In this talk, the second of Aston University’s ‘Society matters LIVE’ series, Dr Volker Prott will invite attendees to take a step back and explore the partition of India from a global historical perspective. Why did partition seem inevitable to so many people 75 years ago, even if they saw trouble ahead? Where does the idea of partition even come from? Why did so many partitions occur in the twentieth century and in the context of decolonisation? Dr Volker Prott, senior lecturer in history at Aston University, said: “The partition of India has become a synonym of tragedy and unimaginable human suffering. “Partition is also now seen by many as a massive diplomatic failure, giving rise to the Indo-Pakistani conflict, one of the most bitter and long-lasting territorial disputes since the end of the Second World War. “We will consider other partition examples, such as Ireland, Palestine, India, and also Germany, Korea, and Vietnam in order to tease out the concept of it and understand what it means in different contexts. “And of course, we will pay attention to the partition, discussing its many facets, and taking the time to explore ways to overcome its divisive legacy.” You can sign up to the free event here. You can listen to the latest podcast episode of ‘Society matters’ with Dr Volker Prott, who speaks about the legacy of India and Pakistan’s independence with journalist Steve Dyson, here. You can find out more about how Aston University’s history department is marking 75 years since Indian partition here. For more information about studying history at Aston University visit our website.
Driving the Ambitious $30M Plan for an Autonomous Vehicle Test Track and Research Center
Innovation and the automobile industry are on the move at UConn -- after four years of planning, coordinating, and developing, a major project is moving closer to reality in Connecticut: UConn’s Board of Trustees recently approved an option agreement to sell 105 acres in the southwest portion of the school’s Mansfield Depot Campus to a private company — Promesa Capital LLC — headed by Cortese, who would lead a group of investors in developing the site as the region’s first-ever connected and autonomous vehicle test track and research facility. Such a facility, Jackson and Cortese said, would be a boon for the university and region, helping make UConn a leader in autonomous vehicle research, technology and safety. “My goal is to raise the stature of UConn to a school where world-class research takes place on this technology, and students come to UConn specifically to work with leading faculty on projects that will change the way we travel,” Jackson said. “UConn will be transformational in terms of research and will provide a world-class facility to open opportunities we’ve never had before for the future of transportation.” August 15 - Hartford Business Journal The endeavor has the potential for lasting positive impact in areas including innovation, research, investment, and the economy, and Eric Jackson -- director of the Connecticut Transportation Safety Research Center at UConn -- is at the forefront of this exciting development. If you are a journalist looking to know more, let us help. Simply click on Jackson’s icon to arrange an interview today.
Aston University and ADInstruments Ltd (ADI) enter 24-month knowledge transfer partnership to develop ground-breaking animal telemetry system World-leading expertise in neuroscience to help bring game-changing system to market Outcomes of KTP will feed directly into the product hardware and software development, ensuring technological advantage for ADI. Aston University has teamed up with research software experts ADInstruments Ltd (ADI) through a knowledge transfer partnership to develop a revolutionary dual-function wireless telemetry system for neuroscience research that is set to transform how implanted biosensors are used for data generation in animals. Telemetry is the automatic recording and transmission of data from remote or inaccessible sources to an IT system in a different location for monitoring and analysis. ADI has an established reputation for developing, supplying and supporting its customers in specific areas of life science research, particularly in cardiovascular science. The company has recently acquired Kaha Sciences, which has developed ground-breaking telemetry technology that can be used to measure neuroscience-relevant signals in free-moving animals for research. The company is looking to use the KTP to harness the world-leading expertise of Aston University to build their reputation in neuroscience. Mark de Reus, head of support at ADInstruments, said: “The evidence-base of research papers, training and support materials from Aston University will be invaluable in improving the product design, identifying development opportunities and embedding a culture of neuroscience within the company.” A knowledge transfer partnership (KTP) is a three-way collaboration between a business, an academic partner and a highly qualified graduate, known as a KTP associate. The UK-wide programme helps businesses to improve their competitiveness and productivity through the better use of knowledge, technology and skills. Aston University is the leading KTP provider within the Midlands. The Aston University team features Professor Gavin Woodhall and Dr Stuart Greenhill from its Pharmacy School’s Pharmacology and Translational Neuroscience Research Group. Professor Woodhall is co-director of the Institute of Health and Neurodevelopment (IHN) and a neuroscientist who studies epilepsy and schizophrenia in rodent models of disease. Dr Stuart Greenhill is a member of IHN and senior lecturer in neuroscience, with a longstanding track record in developing and deploying novel and difficult mechanisms of recording from brain tissue both in vivo and in vitro. Dr Stuart Greenhill said: “It is a privilege to be involved in the development of this important technology, which will be invaluable to thousands of research groups across the globe, and we are delighted to be able to help the product team realise the potential of this device.”
Potential long-term treatment for asthma found - new research
New approach tackles one of the causes of asthma, not just its symptoms In treated mice, symptoms virtually disappeared within two weeks Further research needed before the treatment can be trialled in humans. A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London. In tests in mice, the researchers were able to virtually eliminate asthmatic symptoms within two weeks and return their airways to near normal. Just under 5.5 million people in the UK receive treatment for asthma and around 1,200 people die of the disease each year. Asthma causes the airways to become thickened and constricted, resulting in symptoms such as wheezing and shortness of breath. Current treatments, including steroids, provide short term relief from these symptoms, by either relaxing the airways or reducing inflammation. However, no current drugs address the structural changes asthma makes to the airway and lungs, in order to offer a longer-lasting treatment. Lead researcher, Dr Jill Johnson, from Aston University’s School of Biosciences, said: “By targeting the changes in the airway directly, we hope this approach could eventually offer a more permanent and effective treatment than those already available, particularly for severe asthmatics who don’t respond to steroids. However, our work is still at an early stage and further research is needed before we can begin to test this in people.” The research focused on a type of stem cell known as a pericyte, which is mainly found in the lining of blood vessels. When asthmatics have an allergic and inflammatory reaction, for example to house dust mites, this causes the pericytes to move to the airway walls. Once there, the pericytes develop into muscle cells and other cells that make the airway thicker and less flexible. This movement of the pericytes is triggered by a protein known as CXCL12. The researchers used a molecule called LIT-927 to block the signal from this protein, by introducing it into the mice’s nasal passages. Asthmatic mice that were treated with LIT-927 had a reduction in symptoms within one week and their symptoms virtually disappeared within two weeks. The researchers also found that the airway walls in mice treated with LIT-927 were much thinner than those in untreated mice, closer to those of healthy controls. The team are now applying for further funding to carry out more research into dosage and timing. This would help them to determine when might be the most effective time to administer the treatment during the progress of the disease, how much of LIT-927 is needed, and to better understand its impact on lung function. They believe that, should this research be successful, it will still be several years before the treatment could be tested in people. The research was funded by the Medical Research Council, part of UK Research and Innovation and is published in Respiratory Medicine.
Is Chechnya next as the war in Ukraine shows no signs of stopping?
A long history of conflict in regions such as Eastern Europe, the Balkans and Russia shows these conflicts often grow and eventually draw in other armies or countries. With all eyes on the ongoing war between Russia and Ukraine, there are serious concerns that the powder keg could soon blow. Augusta University's Dr. Craig Albert shares his expertise on war, terrorism and what could be next for the region. As this war between Ukraine and Russia goes on, how does Chechnya come into play? "Chechnya has units fighting on both sides of the conflict. There is a large contingent of independence fighters, rebels and militants fighting for Ukraine, as they have historical grievances with Putin and Russia dating to the Russo-Chechen wars beginning in the early '90s. The official stance of Chechnya, however, under the dictatorship of Kadyrov, is pro-Putin, and has sent upwards of 10,000 troops to fight against Ukraine. Thus, we have the potential of an ethnic civil war breaking out within Chechnya, as they dispute their differences on the battlefield." Do they look at this as an opportunity to break free from Russia? "There are many Chechens that may think this is the perfect strategic opportunity to break away from Russia and claim independence. Others within Chechnya see this as a perfect opportunity to carry out the deeds of the Islamic Caucasus Emirate, officially a part of ISIS, and claim more space for ISIS to operate. It should be noted, most of the civilians just want to live in peace and have economic opportunity as they are still recovering from decades of war in the '90s-2000s." What would that look like if they decided to go on attack? "Depending on which group initiates conflict, it would most likely look like some form of terrorism or insurgency operation. Small-scale and limited in scope. Political assassination could also come into play depending on the side of the people that seek violence." If you’re a journalist looking to know more about the war between Ukraine and Russia and how Chechnya may soon be a factor, then let us help with your questions and coverage. Dr. Craig Albert is director of the Master of Arts in Intelligence and Security Studies at Augusta University. He is a leading expert on war, terrorism and American politics. This is an important national and international issue. Albert is available to speak with media – simply click on his name to arrange an interview today.
Podcast: The partition of India: an ‘evil act’ or ‘rush to grant independence’?
Aston University academic discusses need to understand what resulted in up to two million deaths The partition formed part of a global pattern of expanding nation-states, fitting populations to borders, and decolonisation throughout the 20th century Debate now needed to find ways to accommodate human diversity rather than pulling people apart The partition of India at the end of the Second World War was not an “evil scheme” but a case of being “overtaken by events”, according to an academic at Aston University. Dr Volker Prott, a senior lecturer in modern history, spoke about the legacy of India and Pakistan’s independence in the latest episode of the ‘Society matters’ podcast series, presented by journalist Steve Dyson. Dr Prott said there was a “bitter irony” in “celebrating” the 75th anniversary of the partition and independence of India and Pakistan, granted on 15 August 1947. But he argued that now was the time to overcome divisions in society caused by Britain’s colonial past. He said: “Partition is very much an ambivalent event because, on the one hand, there is indeed grounds for celebration because it meant independence from British colonial rule for India and Pakistan … but at the same time partition was a reason for frustration and then, further on, it was a cause of violence.” Historians have estimated up to 20 million people were displaced in the years following partition, with the death toll “somewhere between 200,000 and two million people”, and possibly hundreds of thousands of girls and women suffering rape and abduction. Partition also led to a lasting long-term conflict between India and Pakistan involving several wars and the break-up of Pakistan in 1971. Dr Prott said Britain had come in for a lot of criticism due to the violence, with various historical studies regarding Indian partition as a “deliberate design” to weaken India and secure long-term British influence. But he argued that Britain was “overtaken by events” in the sense they underestimated “the dynamic for independence” and the huge potential for violence. “That’s the moment they rushed independence and rushed partition … a quick and easy exit option for the British Empire,” he said. As a result, no-one put mechanisms in place for refugee or minority protection, or to draw borders “in a sensible way”. Dr Prott said the partition of India was not an exception, but part of a larger historical pattern throughout the 20th century that also included new borders drawn that split Ireland, Palestine, Korea, Germany, Vietnam and Cyprus. This pattern comprised of three factors – the global expansion of the nation-state, “international stability” involving “fitting populations to borders”, and decolonisation leading to “friction and conflict”. He said: “We shouldn’t blame the British for plotting partition. It wasn’t an evil scheme they came up with.” But he stressed that the British did try to avoid assuming responsibility for more than a century of colonial rule in India, including “colonial violence, economic exploitation, and politicising religious identities of Muslims and Hindus” in particular. Dr Prott said the “starkest example” of a nation taking responsibility for the past was his own country, Germany, which committed the Holocaust, the “most extreme case of genocide in history”. Germany had come to terms with its crime and guilt, and accepted the need to work towards reconciliation. He said this was mostly seen as a historic problem in Germany, “but in Britain the legacy of colonialism is with us every day” with the Black Lives Matter movement, decolonising the curriculum in universities, changing street names, and removing controversial statues. He said: “We should see this dealing with our colonial past as an opportunity to bridge existing divides, to learn from each other. We need an open-ended debate.” Many people, he said, have very extreme views on the partition. Some praised the British Empire and said the violence was all because of racial hatreds, while others claimed people lived in harmony for centuries and problems were only caused by “evil British plotting”. “What we need to do is move away from these simplistic views of the past. History shows us that partitions very often cause more problems than they solve and we should try to find ways to accommodate human diversity rather than pulling people apart.” Aston University is marking the 75th anniversary of Indian partition by taking part in an exhibition at Birmingham New Street Station called ‘Children of the Railway: The Partition of India 75 Years On’, which opens on 6 September for three weeks. Dr Prott is also giving a public talk on partition at 5pm on 25 August at the Hockley Social Club.
Aston University graduate takes boxing gold for Team England at Commonwealth Games
Delicious Orie came from behind to win Commonwealth Games men's super-heavyweight gold He beat India's Sagar Sagar in the NEC Arena to claim England's second gold of the day The 25-year-old graduated from Aston University in April having studied economics and management. Aston University alumnus, Delicious Orie, has won a boxing gold medal at the 2022 Commonwealth Games in Birmingham. The 25-year-old came from behind to win in the men's super-heavyweight fight, beating India's Sagar Sagar in the NEC Arena on 7 August to claim England's second gold of the day. Born in Moscow to his Nigerian father, Justin, and Russian mother, Natalie, he spent the first seven years of his life in the city of Voronezh, 520 kilometres from the Russian capital, before the family moved to London to escape racism and to seek a better life. There was another upheaval at the age of 11, when the family moved to Wolverhampton. He once again threw himself into his schooling, enjoyed whatever extracurricular activities were on offer and took advantage of the opportunities he was afforded. Delicious graduated with a first class honours degree from Aston University in April having studied economics and management (2020). Speaking to BBC Sport after the fight, Delicious said: “I was an emotional wreck earlier but when that final bell went, I knew I had it in the bag. “The only way I did it was through the support of the fans. “I had two rounds to prove myself and I'd never heard a roar like that. The English fans are the best in the world. “I was determined to not let anyone else win. I've never felt anything like this.” Kerrie Holland, director of alumni relations and development at Aston University, said: “We are just delighted for DJ for this amazing achievement. “He’s a fantastic ambassador for Aston University and has been so generous with his time to inspire alumni and students – including as the cover star of the 2021 alumni magazine! “We are proud of all of our Aston University graduates and I know the whole #TeamAston family will be celebrating Delicious’ Commonwealth Gold alongside him.” You can find out more about Delicious Orie’s story here.
The Christopher J Hewitt Prize for exceptional student citizenship in the College of Life and Health Sciences at Aston University has been awarded to Hanan Tahir a fourth year MPharm student, in recognition of his support in helping colleagues to develop and achieve their goals through mentoring and for his positive and supportive outlook, felt by all those around him. The prize is named after and in tribute of Professor Christopher J Hewitt FREng who was pro-vice chancellor and executive dean of the School of Life and Health Sciences and professor of biological engineering from November 2014 until July 2019. Chris sadly passed away on 25 July 2019 at the age of 50; an eminent scientist and truly devoted family man. To commemorate Chris’s life and to celebrate the values that he held dear, the Christopher J Hewitt Prize was established in 2021 to recognise exemplary citizenship through support of other students, contribution to the Aston University community or achievement in the face of adversity. The judging panel, which consisted of four research fellows and Chris’s widow Sandra Hewitt, felt that Hanan had achieved a lot through his work with Aston University student societies, where he is president of the Aston Pharmacy Society. Hanan also set up a mentoring scheme for first and second year students to help ease them into University life after the Covid-19 pandemic. The judges noted the substantial amount of charity work undertaken by Hanan including hiking up Snowden to raise £9000 for Syrian Refugees. They were also impressed by the nominations outlining the sense of fun and joy Hanan has helped to foster amongst his student peers. On receiving his award, Hanan said: "It's within our human nature to care for and support each other. We've grown to be so successful because we have always chosen to look out for others rather than isolate and try to go it alone. And I have always believed that an integral key to happiness is community. “I am honoured to have received this award. I am even more honoured that my efforts have been noticed and recognised. Aston University has always put inclusivity and community in everything it does and I hope that we all continue to emanate the values of this University as we progress through our lives." Sandra Hewitt, Chris’s widow, added: “It was an honour to once again be able to be part of the judging panel for the Christopher J. Hewitt Memorial Prize. Again, this year the candidates all exhibited the qualities and values of the prize, however we felt Hanan was a worthy winner for all the reasons mentioned above. Chris worked hard but he liked to party harder so the fact that Hanan’s nominations also mentioned his sense of joy and fun was especially relevant." Professor Anthony Hilton, executive dean of the College of Life and Health Sciences, said: “I am delighted Hanan is this year’s recipient of the Christopher J Hewitt Prize. It makes me exceptionally proud to see members of the College demonstrating the culture and values we hold dear and being held in such high regard by their peers.” The panel also highlighted the exceptional achievements of Negin Gholampoor for her work as the Aston Medical School representative to the British Medical Association and for striving to improve the systems around her and effect change for the benefit of her peers. A special mention was made for Erika Pond for her commendable display of citizenship when providing CPR to a stranger in need. For more information about the College of Health and Life Sciences please visit our website and for information about studying Pharmacy at Aston University go to our course pages.