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3 Things A Climate Scientist Learned From Jane Goodall
In a recent Forbes article, Marshall Shepherd reflects on three key lessons he has drawn from the life and work of Dr. Jane Goodall. Shepherd frames Goodall’s legacy—spanning primatology, conservation, and public engagement—as deeply instructive for climate scientists and environmental advocates. He argues that her methods and mindset have more to teach than simply how to observe nature; they speak to how we engage with the world. First, Shepherd highlights immersion: Goodall’s decades of patient observation in the Tanzanian forests demonstrates the power of being physically—and emotionally—present to truly learn from ecosystems. For Shepherd, climate science must go beyond remote data collection: getting into the field and understanding local realities matters. Second, he emphasizes patience. Goodall’s willingness to wait, sometimes for years, for breakthroughs in understanding primate behavior offers a lesson for climate researchers, whose progress may unfold over decades. Third, he admires her tenacity—a commitment sustained over a lifetime, even under adversity. Shepherd suggests that tackling climate change requires that same kind of enduring resolve, especially when public attention or funding waxes and wanes. Through these reflections, Shepherd presents Goodall not just as an icon of conservation but as a model for scientific humility and perseverance. He invites readers to see the parallels between animal behavior research and climate work—and to adopt practices of listening, patience, and resolve in confronting our planet’s changing trajectory. Dr. J. Marshall Shepherd is a leading international weather-climate expert and is the Georgia Athletic Association Distinguished Professor of Geography and Atmospheric Sciences at the University of Georgia. Dr. Shepherd was the 2013 President of American Meteorological Society (AMS), the nation’s largest and oldest professional/science society in the atmospheric and related sciences. View his profile here Dr. J. Marshall Shepherd is a leading international weather-climate expert and is the Georgia Athletic Association Distinguished Professor of Geography and Atmospheric Sciences at the University of Georgia. He's available to speak with the media about this topic - simply click on his icon now to arrange an interview today.
How LSU is Helping Keep Louisiana at the Center of the Nation’s Seafood Map
1. Strengthening the Seafood Workforce Through outreach programs like Louisiana Fisheries Forward, a partnership between Louisiana Sea Grant and the Louisiana Department of Wildlife and Fisheries, LSU helps fishers and processors modernize their operations. These voluntary programs teach best practices in handling, traceability, and sustainability — directly improving product quality and market reputation. LSU’s extension agents also provide hands-on disaster recovery assistance after hurricanes and market disruptions, helping ensure Louisiana’s seafood workforce remains resilient and ready for the next season. 2. Building Seafood Resilience The total economic value for oysters in 2018 was more than $180 million. Resilience defines LSU’s seafood science. Researchers at the LSU AgCenter and Louisiana Sea Grant are leading selective breeding programs and developing genetic tools to combat disease, temperature changes, and salinity stress. With a powerful combination of hatchery capacity, genetics expertise, and industry collaboration, LSU is helping Louisiana’s seafood industry adapt faster and smarter — protecting both the food supply and the economic backbone of coastal communities. 3. Powering Economic Growth Every part of LSU’s seafood research and outreach ties directly to Louisiana’s economy. AgCenter economists analyze market data and advise state and federal partners on strategies to grow the seafood sector. Meanwhile, Sea Grant specialists help entrepreneurs develop value-added seafood products, from branded lines to ready-to-eat options, that increase profit margins and create new jobs in coastal towns. By helping Louisiana seafood businesses stay competitive, LSU keeps more of the industry’s economic benefits right here at home. 4. Supporting Communities Louisiana’s seafood industry faces constant challenges. LSU’s coastal extension agents and Sea Grant programs provide on-the-ground support to help communities recover and rebuild after disasters. Whether assisting with dock repairs, connecting fishers to relief programs, or helping restart operations, LSU’s commitment ensures that Louisiana’s coastal workforce can weather any storm. 5. Preparing the Next Generation LSU’s work extends from the lab to the dock — and into the classroom. New research and education programs are training future scientists, producers, and entrepreneurs to continue Louisiana’s seafood legacy. For new LSU students interested in the coast, Bayou Adventure, a trip created by the College of the Coast & Environment (CC&E), was designed specifically to educate incoming freshmen about some of the challenges and marvels of the Louisiana coastline. The trip stops at sites that showcase "not just the significance of these areas to the state and nation, but the important work that is being done to sustain and preserve them," said Clint Willson, dean of CC&E. Through workforce development, hands-on learning, and applied research, LSU is shaping the next wave of innovators who will protect Louisiana’s coast and ensure its seafood remains world-renowned. Looking Ahead As the seafood industry faces new challenges and opportunities, LSU’s mission remains clear: to protect Louisiana’s coast, empower its seafood workforce, and ensure the state remains synonymous with the best seafood in America.
UF scientist studies muscle loss in space to benefit astronauts and patients on Earth
Astronauts traveling to Mars will face many challenges, but one of the most serious is muscle loss during long space missions. A new study led by University of Florida researcher Siobhan Malany, Ph.D., sheds light on how human biology changes in microgravity and could help protect astronaut health while also offering hope for patients with muscle-wasting diseases on Earth. Malany, an associate professor in the College of Pharmacy, a member of UF’s Astraeus Space Institute, and director of the in-space Biomanufacturing Innovation Hub, recently published findings showing how muscle cells adapt in space. Her team studied bioengineered three-dimensional muscle tissues derived from biopsy cells from both younger and older individuals and observed how they responded to electrical stimulation in microgravity. These micro-scale tissues called “tissue chips” were given nutrients and electric pulses autonomously in a miniature laboratory the size of a shoe box called a CubeLab.x. A camera system inside the box recorded the rate of muscle contraction. “This research is about more than just space,” Malany said. “By understanding how muscle tissue deteriorates much faster in microgravity, we can uncover new strategies to address muscle loss that occurs naturally with aging and with age-related diseases here on Earth.” Siobhan Malany studies the effects of microgravity on human muscle biology using an automated tissue chip system. View her profile here The study found that younger muscle tissue showed more pronounced changes in mitochondrial pathways — cellular systems that produce energy — than older tissue did when exposed to microgravity. Researchers also discovered that, on Earth, older muscle tissue responds less to electrical stimulation than younger tissue. But in space, the younger tissue showed a noticeable drop in its ability to contract, suggesting that younger muscle may experience a greater change when exposed to the space environment. These insights may help researchers design new treatments to protect muscles in astronauts during long missions, as well as develop therapies for people experiencing age-related muscle loss on Earth. The project was part of UF’s broader efforts to advance space biology. Through the Astraeus Space Institute, UF brings together experts across disciplines, from medicine and pharmacy to engineering and plant science, to address the unique challenges of space exploration. “UF researchers are helping lay the groundwork for humanity’s next giant leap,” Malany said. “It’s exciting to see our work contribute to both the health of astronauts and the lives of patients back home.” UF’s leadership in space biology is strengthened through collaboration with partners including the Kennedy Space Center Consortium and the Center for Science, Technology and Advanced Research in Space), both initiatives bringing together universities in Florida’s high-tech corridor, government agencies and industry leaders. Malany’s work also builds on long-term collaborations with AdventHealth, using donated tissue samples to model age-related muscle changes in space. Her team also works with SpaceTango, a NASA-certified aerospace company, to design the CubeLab that flew to the International Space Station on multiple SpaceX missions. Looking ahead, Malany and her team are developing new ways to study astronaut-derived cells, including both skeletal and heart muscle, generated from blood samples. These “avatars” could help researchers track changes before, during and after space missions, providing an unprecedented window into how microgravity affects the human body. “Now we can study cells from individual astronauts and see how they respond over time,” Malany said. “This helps us understand the risks of long-term spaceflight and also gives us a platform for testing potential treatments for muscle-wasting conditions on Earth.” By using tissue chips, small, bioengineered devices that mimic the structure and function of human organs, scientists in space can gather data more quickly and accurately than with traditional animal studies, potentially accelerating the discovery of therapies for aging-related muscle loss. Looking to know more about this amazing research or connect with Siobhan Malany - simply click on her icon now to arrange an interview today.
Why Brokers Are Canada’s New Mortgage Rockstars
There’s a quiet revolution happening in Canadian mortgage lending—well, as “quiet” as anything can be when two-thirds of Canadians are shouting, “We’d rather deal with a broker than a bank!” According to the most recent Mortgage Professionals Canada (MPC) Consumer Survey, 67% of Canadians now say they’d rather work with a mortgage broker than a bank. Among those who already have? A whopping 81% would do it again. That’s not just a statistic. That’s a standing ovation. The Great Mortgage Broker Boom According to recent MPC data, broker market share reached 33% in 2024—a four-point increase in just two years. Nearly half of all borrowers now choose brokers. The message is clear: Canadians are tired of sales reps; they want advocates who speak human, not policy manual. And who can blame them? With 1.2 million mortgages renewing in 2025 and average payments increasing by $513 a month, people aren’t just rate-shopping anymore—they’re seeking guidance, reassurance, and maybe a bit of hope. Let’s face it: they want their cake and still be able to heat their home too. Why This Matters—Especially for Seniors I work with Canadians aged 55+ every day, and about three-quarters of them are homeowners. They’ve done everything right: worked hard, paid off debt, raised families, and built wealth through their homes. But now, many feel… trapped by them. Here’s the reality: Mortgage renewals are costing hundreds more monthly (some facing 15–20% jumps) Inflation is eating into fixed incomes; and downsizing, aging in place, or tapping into home equity all feel like high-stakes decisions. Almost 80% of Canadians over 55 say their savings and pensions aren’t enough. (Source: Home Equity Bank Ipsos Survey) According to this same survey, half of respondents believe home equity is crucial for retirement—yet 76% feel pressured to downsize even if they’d rather not trade their garden for a balcony (or their favourite hairdresser for whoever’s closest to the condo). What they don’t need: A one-size-fits-all sales pitch from someone who thinks “retirement” means early-bird specials and Sudoku marathons. What they do need: A mortgage broker who listens, educates, compares options, and helps them sleep at night—not just sign on the dotted line. The Missing Link: Transactional vs. Conversion Sales Traditional mortgages are what we call commodities, sold using a transactional method. In this approach, the need is obvious—the customer wants a mortgage—and the focus is on competing for the best price and terms. It’s fast, efficient, and, let’s be honest, a little impersonal. It’s the classic hammer-and-nail approach: every client looks like a nail, and the broker just keeps swinging rates and terms until something sticks. That may work for a first-time buyer chasing the cheapest five-year fix—but for seniors? It’s about as effective as putting a Band-Aid on a broken arm. The 55+ demographic doesn’t want a hammer. They want a conversation. They want to understand how to stretch their pension income, cover rising expenses, and prepare for life’s curveballs—like healthcare costs or home repairs—without feeling like they’re going backwards financially. That’s why this is not a transactional sale; it’s a conversion sale. A transactional sale happens when someone already wants what you’re selling—you’re just facilitating the purchase. A conversion sale, however, is when the client doesn’t yet believe they need or want what you’re offering. You’re not closing a deal; you’re changing a mindset. And that’s the secret sauce for brokers working with older Canadians. You’re not selling debt—you’re offering financial flexibility. You’re helping people reframe home equity from a “last resort” into a retirement resource. How Brokers Can Shift the Conversation Lead with empathy, not economics. Ask about life goals, not loan size. Do they want to age in place, help kids, or reduce financial stress? Start with why, then move to how. Rebrand the conversation. Words matter. “Mortgage” can feel like failure. Try “home-equity strategy” or “retirement cash-flow plan.” You’re not adding debt—you’re unlocking options. Talk cash flow, not contracts. Focus on income versus expenses, inflation resilience, and emergencies. Discuss how home equity can supplement pensions, create predictable, guaranteed income (like our parents had), and—most importantly—boost that all-important sleep score. Include the family. Adult children often play a major role. Involve them early—these are emotional, multi-generational conversations, not just financial ones. Educate, don’t sell. Show examples, calculators, and real-life case studies. Transparency earns trust—and trust is the true currency in a conversion sale. When brokers shift from “rate pitching” to “retirement planning,” they go from hammer-swingers to problem-solvers—and that’s where the real magic (and business growth) happens. What Mortgage Brokers Bring to the Table The broker market is projected to grow at a 5% CAGR through 2030, driven by consumers demanding personalization over cookie-cutter lending. And the reverse-mortgage space just got a serious glow-up. Home Trust Bank has just entered the market, announcing its new Equity Access Reverse Mortgage product at this week's Mortgage Professionals Conference in Ottawa. That brings the total to four active lenders in Canada’s reverse-mortgage space: HomeEquity Bank, Equitable Bank, Home Trust Bank, and Bloom Finance Company. More lenders mean more credibility—or, as I like to call it, street cred for seniors. The kind that lets retirees walk down the street (or the fairway) with a little swagger, knowing their financial toolkit has options. With more players in the mix comes more choice, sharper pricing, and—most importantly—a sense that reverse mortgage products have finally crossed over from “fringe” to financially fashionable. Reverse mortgages are no longer the “we-don’t-talk-about-that” cousin at the financial family dinner—they’re sitting proudly at the adult table. The product is being normalized—treated as the legitimate, strategic retirement tool it has always been. So, brokers—be honest. Isn’t it time you caught up to the trend? Reverse mortgages have gone from taboo to totally credible. And if your clients still say, “We’re just not reverse-mortgage people,” that’s your cue to help them unpack that posture of financial marginalization. Because what they often mean is, “We don’t want to feel old, desperate, or dependent.” That’s not who they are—and that’s not what this product is. It’s not about retreating; it’s about reframing. Helping them see home equity as strength, not surrender. Because empowering clients to live comfortably, confidently, and cash-flow secure isn’t just good business—it’s the kind of advocacy that gives everyone involved a little swagger. Older Canadians Need Advocates—Not Just Advisors As a spokesperson for this group, I urge brokers to master Equity Literacy—the ability to explain complex tools like reverse mortgages and HELOCs in plain language. It’s about helping retirees access equity wisely, preserve benefits, and create peace of mind. Canadian reverse-mortgage debt reached $8.2 billion in mid-2024—an 18.3% year-over-year increase. (Source: Office of the Superintendent of Financial Institutions - OSFI). Canadians are catching on: their house can help them, not haunt them (could not resist the Halloween joke). Help seniors understand the range of uses for Reverse Mortgages like paying off high-interest debt, helping family through early inheritance or gifting, and supplementing retirement income to maintain independence. And here’s where brokers can really shine—by guiding family conversations about inheritance, housing, and aging in place. According to CMHC’s 2025 Mortgage Consumer Survey, 41% of first-time buyers used a gift or inheritance to cover mortgage costs. That's up from 30% the year before. Those gifts averaged nearly $80,000. The Bank of Mom & Dad just got promoted to Wealth Management HQ. To the Canadian mortgage broker industry You’re not just in the mortgage business—you’re in the dignity business. You help Canadians stay in their homes, reduce stress, and live comfortably in retirement. With home sales slowing and fewer purchase deals, this is your moment. Building expertise in the 55+ market isn’t just good karma—it’s good business. How to start: educate your database about equity-release benefits and tax-free cash flow; host workshops on “Aging in Place with Equity”; partner with financial planners, lawyers, healthcare providers—and yes, Realtors—to build a holistic approach to retirement housing. Involve adult children in every conversation; they’re tomorrow’s clients. The data says Canadians need you more than ever. And I’ll say it louder: so do I. Let’s make retirement planning better, smarter, and more human—one conversation at a time. So here’s the truth: the 55+ crowd doesn’t need rescuing—they need respect. They’re not clinging to the past; they’re funding their future. They don’t want pity; they want power—and they’ve earned it. This generation built Canada’s equity base—literally—and now it’s time they get to use it wisely, proudly, and on their own terms. Whether that means a new roof, a family gift, or finally taking that long-postponed trip to Italy, it’s not about borrowing money—it’s about buying freedom. So, brokers, financial pros, and anyone guiding retirees—remember: your role isn’t to sell products. It’s to spark possibilities. To help older Canadians move from fear to freedom, from “we’re not those people” to “why didn’t we do this sooner?” Because the real revolution in retirement isn’t about rates or renewals. It’s about reclaiming confidence, creating financially viable futures, and knowing you’ve made a real difference—something your clients will remember long after the ink dries. Trust me, that’s far more gratifying than handing out a 4.99% five-year fixed. I want to know what you think. Send me your feedback. Want more insights like this? Subscribe to my free newsletter here, where I share practical strategies, real-world stories, and straight talk about navigating retirement with confidence—not confusion. Plus, all subscribers get exclusive early access to advance chapters from my upcoming book. For Canadians 55+: Get actionable advice on making your home equity work for you, understanding your options, and living retirement on your terms. For Mortgage Brokers and Financial Professionals: Learn how to become the trusted advisor your 55+ clients desperately need (and will refer to everyone they know). This isn't just another revenue stream—it's your opportunity to build lasting relationships in Canada's fastest-growing demographic. Sue Don’t Retire…Re-Wire!
Nursing researcher receives over $500K in prestigious grants
For the first time in nearly 15 years, a faculty member from Augusta University’s College of Nursing has been awarded a grant from the National Institutes of Health. Blake McGee, PhD, has secured an R03 award of $176,331 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to study Medicaid’s expanded role in late postpartum maternal health. But he hasn’t stopped there as McGee is also part of the fifth cohort of Betty Irene Moore Fellows, a prestigious program for nurse leaders and innovators that has awarded CON half a million dollars to support his research project and leadership development. McGee, the prelicensure department chair and an associate professor, is collaborating with colleagues from other Georgia universities on both studies, which are occurring simultaneously. “I began my career as an ER nurse and have always wanted to ask bigger questions about the challenges facing patients and how we might best address them as a society,” said McGee, who was recently selected for publication in Blood Advances, the American Society of Hematology’s journal. “As nursing scientists, we are uniquely poised to ask questions about healthcare policy, specifically from the vantage point of the impact that policy choices have on patients and their health outcomes.” This century, the United States has seen rising maternal mortality rates with alarming racial disparities. Over half of these deaths occur in the postpartum period, with 23% occurring more than six weeks after delivery. Medicaid expansion covers pregnant women in households below 138% of the Federal poverty level through postpartum day 60, which has been associated with decreased mortality and reduced racial disparity in maternal death. At the time of grant submission, pregnancy Medicaid eligibility traditionally lapsed 60 days after delivery, leaving postpartum people vulnerable to disruptions in care. McGee’s work aims to identify changes in maternal health care use and health outcomes 60 days to 1 year after delivery that were associated with state Medicaid expansions (2007–19). The team will examine whether the effects of expansion vary by maternal race or ethnicity and will explore whether patient-reported health care access and quality mediate the relationships between expansion and outcomes. “My hope is that after the study we’ll have a better understanding of how health and health care use change for women in this crucial late postpartum period and how they may differ for people of different backgrounds,” said McGee. “Due to the sample design, findings will reliably inform optimal policy for postpartum coverage duration.” He expects this study to provide preliminary data for a future R01-funded study that directly examines the impact of extending the duration of postpartum Medicaid under the American Rescue Plan. As part of the Betty Irene Moore Fellowship, McGee is one of 15 fellows across the nation in a curriculum co-delivered by the UC Davis School of Nursing and Graduate School of Management. A project coordinator from AU’s School of Public Health will also assist with the fellowship project. McGee hopes to involve graduate research assistants or recent alumni as research associates on the team. Specifically, McGee will be studying the Georgia Pathways to Coverage Program, making him one of the only academic researchers in the nation funded to do so. “As a researcher, it is always a privilege to engage in topics that directly impact the current state of health care, and I’m honored to tackle projects that are so relevant to today’s health policy headlines,” he said. Georgia stands out among other states that are exploring an extension of Medicaid to low-income, working-age adults who demonstrate a monthly commitment of 80 hours to an employment-related activity. By studying the effects of this program, McGee predicts the findings will be highly relevant to anticipating the impact of recent Medicaid changes at the federal level and may indicate differences between Pathways participants and those who might qualify but remain uninsured. This focus could provide data that helps the state target enrollment efforts. The state’s own logic model predicts that the program will reduce hospitalizations, and McGee is eager to determine the program’s success. “Our findings should be helpful to the state to better understand those enrolling, what their experience with increased access to care has been and how their health has improved after receiving coverage,” McGee said.
Supporting the development of advanced computing hardware, the National Science Foundation (NSF) awarded Supriyo Bandyopadhyay, Ph.D., Commonwealth Professor in the Department of Electrical and Computer Engineering at the Virginia Commonwealth University (VCU) College of Engineering with more than $300,000 to develop processor-in-memory architecture using quantum materials. “This is one of the first mainstream applications of quantum materials that have unusual and unique quantum mechanical properties,” Bandyopadhyay said. “Quantum materials have been researched for more than a decade and yet there is not a single mainstream product in the market that utilizes them. We want to change that.” The four-year project, titled “Collaborative Research, Foundations of Emerging Technologies: PRocessor In Memory Architecture based on Topological Electronics (PRIMATE),” aims to advance computing hardware and artificial intelligence by integrating topological insulators and magnetic materials. Topological insulators are a special material with an electrically conductive surface and an insulated interior. They have special quantum mechanical properties like “spin-momentum locking,” which ensures the quantum mechanical spin of an electron-conducting current on the surface of the material is always perpendicular to the direction of motion.This marks the first time such quantum materials will be used in a processor-in-memory system. “We place a magnet on top of a topological insulator,” Bandyopadhyay said. “We then change the magnetization of the magnet by applying mechanical strain on it. That changes the electrical properties of the topological insulator via a quantum mechanical interaction known as exchange interaction. This change in the electrical properties can be exploited to perform the functions of a processor-in-memory computer architecture. The advantage is that this process is fast and extremely energy-efficient.” If successful, this approach could reduce energy use and dramatically speed up computing by moving data processing into the memory itself. It addresses the longstanding “memory bottleneck,” the slowdown caused by computers constantly needing to move data back and forth between processor and memory. These efficiencies could make advanced AI more efficient and accessible, paving the way for the first commercially viable applications of quantum materials.. The research is a collaboration with University of Virginia professors Avik Ghosh and Joseph Poon. A VCU Ph.D. student will work on the project and receive training in fabrication, characterization and measurement techniques, preparing them to lead in the rapidly evolving field of computing hardware.
Expert Spotlight: Advancing Child & Youth Behavioral Health with MBC
Children and youth today face increasingly complex mental health challenges, requiring care that is personalized, evidence-based, and responsive to evolving needs. Measurement-Based Care (MBC), also referred to as Measurement-Informed Care (MIC), is a proven framework that leverages client-reported data to guide treatment decisions, enhance engagement, and improve clinical outcomes. With CARF’s updated accreditation standards now requiring MBC in youth services, organizations globally are prioritizing its adoption. On September 30, Greenspace Health brought together a panel of experts including Theresa Lindberg, MSC, LPC, Managing Director for Child and Youth Services, CARF International, who shared real-world examples, lessons learned from successful implementations, and actionable strategies for embedding MBC in youth-serving organizations. The webinar was recorded and is available below for viewing. This is an important topic, and if you are interested in learning more - then let us help. Theresa Lindberg is Managing Director of Child and Youth Services at CARF International. If you are looking to connect with Theresa , view her profile below to arrange an interview today.
A global team of researchers using the new X-ray Imaging and Spectroscopy Mission (XRISM) telescope, launched in fall 2023, discovered something unexpected while observing a well-studied neutron star system called GX13+1. Instead of simply capturing a clearer view of its usual, predictable activity, their February 2024 observation revealed a surprisingly slow cosmic wind, the cause of which could offer new insights into the fundamental physics of how matter accumulates, or “accretes,” in certain types of binary systems. The study was one of the first from XRISM looking at wind from an X-ray binary system, and its results were published in Nature—the world's leading multidisciplinary science journal—in September 2025. Spectral analysis indicated GX13+1 was at that very moment undergoing a luminous super-Eddington phase, meaning the neutron star was shining so brightly that the radiation pressure from its surface overcame gravity, leading to a powerful ejection of any infalling material (hence the slow cosmic wind). Further comparison to previous data implied that such phases may be part of a cycle, and could “change the way we think about the behavior of these systems,” according to Joey Neilsen, PhD, associate professor of Physics at Villanova University. Dr. Neilsen played a prominent role as a co-investigator and one of the corresponding authors of the project, along with colleagues at the University of Durham (United Kingdom), Osaka University (Japan), and the University of Teacher Education Fukuoka (Japan). Overall, the collaboration featured researchers from dozens of institutions across the world. GX13+1 is a binary system consisting of a neutron star orbiting a K5 III companion star—a cooler giant star nearing the end of its life. Neutron stars are small, incredibly dense cores of supergiant stars that have undergone supernovae explosions. They are so dense, Dr. Neilsen says, that one teaspoon of its material would weigh about the same as Mount Everest. Because of this, they yield an incredibly strong gravitational field. When these highly compact neutron stars orbit companion stars, they can pull in, or accrete, material from that companion. That inflowing material forms a visible rotating disk of gas and dust called an accretion disk, which is extremely hot and shines brightly in X-rays. It’s so bright that sometimes it can actually drive matter away from the neutron star. “Imagine putting a giant lightbulb in a lake,” Dr. Neilsen said. “If it’s bright enough, it will start to boil that lake and then you would get steam, which flows away like a wind. It’s the same concept; the light can heat up and exert pressure on the accretion disk, launching a wind.” The original purpose of the study was to use XRISM to observe an accretion disk wind, with GX13+1 targeted specifically because its disk is persistently bright, it reliably produces winds, and it has been well studied using Chandra— NASA’s flagship X-ray observatory—and other telescopes for comparison. XRISM can measure the X-ray energies from these systems a factor of 10 more precisely than Chandra, allowing researchers to both demonstrate the capabilities of the new instrument and study the motion of outflowing gas around the neutron star. This can provide new insights into accretion processes. “It's like comparing a blurry image to a much sharper one,” Dr. Neilsen said. “The atomic physics hasn't changed, but you can see it much more clearly.” The researchers uncovered an exciting surprise when the higher-resolution spectrum showed much deeper absorption lines than expected. They determined that the wind was nearly opaque to X-rays and slow at “only” 1.4 million miles per hour—surprisingly leisurely for such a bright source. Based on the data, the team was able to infer that GX13+1 must have been even brighter than usual and undergoing a super-Eddington phase. So much material was ejected that it made GX13+1 appear fainter to the instrument. “There's a theoretical maximum luminosity that you can get out of an accreting object, called the Eddington limit. At that point, the radiation pressure from the light of the infalling gas is so large that it can actually hold the matter away,” Dr. Neilsen said, equating it to standing at the bottom of a waterfall and shining light so brightly that the waterfall stops. “What we saw was that GX13+1 had to have been near, or maybe even above, the Eddington limit.” The team compared their XRISM data from this super-Eddington phase to a set of previous observations without the resolution to measure the absorption lines directly. They found several older observations with faint, unusually shaped X-ray spectra similar to the one seen by XRISM. “XRISM explained these periods with funny-shaped spectra as not just anomalies, but the result of this phenomenally strong accretion disk wind in all its glory,” Dr. Neilsen said. “If we hadn’t caught this exact period with XRISM, we would never have understood those earlier data.” The connection suggests that this system spends roughly 10 percent of its time in a super-Eddington phase, which means super-Eddington accretion may be more common than previously understood—perhaps even following cycles—in neutron star or black hole binary systems. “Temporary super-Eddington phases might actually be a thing that accreting systems do, not just something unique to this system,” Dr. Neilsen said. “And if neutron stars and black holes are doing it, what about supermassive black holes? Perhaps this could pave the way for a deeper understanding of all these systems.”
Delaware study reveals higher rates of anxiety, substance use among LGBT+ youth
A new study has found that LGBT+ youth in Delaware are experiencing disproportionately high rates of anxiety, depression and substance use compared to their cisgender heterosexual peers. University of Delaware’s Eric Layland, assistant professor in the College of Education and Human Development, and his coauthors reported that nearly one in four Delaware teens identifies as LGBT+, a dramatic increase from earlier state surveys that put the figure closer to 5%. More than one in 20 identified as transgender or nonbinary, reflecting national trends of increased visibility among Generation Z. The study revealed stark mental health differences. About half of cisgender heterosexual youth reported recent anxiety, compared to 75 to 80% of LGBT+ youth. These rates exceed both their heterosexual peers in Delaware and national averages for LGBT+ youth. Substance use patterns also raised concerns. By 8th grade, LGBT+ students reported higher rates of drinking, smoking, vaping and prescription drug misuse. Researchers noted that their substance use looked more like that of 11th grade heterosexual students than their peers in the same grade, pointing to early onset of risky behaviors. These disparities, established in middle school, largely persisted into high school. While substance use increased among all students over time, LGBT+ youth consistently reported higher rates. Based on state population data, the findings suggest there may be 18,000 to 20,000 LGBT+ youth in Delaware, including up to 5,000 transgender and nonbinary youth. The authors say this underscores the importance of ensuring that schools, healthcare providers and community programs have the resources to meet the needs of this population. This is one of the first Delaware-specific studies on youth health disparities by sexual orientation and gender identity using data collected after the height of the COVID-19 pandemic. The results, researchers say, highlight an urgent need for early intervention and affirming support systems for LGBT+ youth across the state. Layland, who specializes in LGBTQ+ development and affirmative interventions, can speak more about specific interventions. He is available by clicking his profile.
Taking discoveries to the real world for the benefit of human health
It takes about a decade and a lot of money to bring a new drug to market—between $1 billion to $2 billion, in fact. University of Delaware inventor Jason Gleghorn wants to change that. At UD, Gleghorn is developing leading-edge microfluidic tissue models. The devices are about the size of two postage stamps, and they offer a faster, less-expensive way to study disease and to develop pharmaceutical targets. These aren’t tools he wants to keep just for himself. No, Gleghorn wants to put the patented technology he’s developing in the hands of other experts, to advance clinical solutions in women’s health, maternal-fetal health and pre-term birth. His work also has the potential to improve understanding of drug transport in the female reproductive tract, placenta, lung and lymph nodes. Gleghorn, an associate professor of biomedical engineering, was named to the first cohort of Innovation Ambassadors at UD, as part of the University’s effort to foster and support an innovation culture on campus. Below, he shares some of what he’s learned about translating research to society. Q: What is the problem that you are trying to address? Gleghorn: A lot of disease has to do with disorganization in the body’s normal tissue structure. My lab makes microfluidic tissue models, called organ-on-a-chip models, that have super-tiny channels about the thickness of a human hair, where we can introduce very small amounts of liquid, including cells, to represent an organ in the human body. This can help us study and understand the mechanism of how things work in the body (the biology) or help us do things like drug screening to test therapeutic compounds for treating disease. And while these little microfluidic devices can do promising things, the infrastructure required to make the system work often restricts their use to high-end labs. We want to democratize the techniques and technology so that nonexperts can use it. To achieve this, we changed the way we make these devices, so that they are compatible with standard manufacturing, which means we can scale them and create them much easier. Gleghorn: One of the problems with drug screening, in general, is that animal model studies don’t always represent human biology. So, when we’re using animal models to test new drugs — which have been the best tool we have available — the results are not always apples to apples. Fundamentally, our microfluidic devices can model what happens in humans … we can plug in the relevant human components to understand how the mechanism is working and then ask questions about what drives those processes and identify targets for therapies to prevent the dysfunction. Q: What is innovative about this device? Gleghorn: The innovation part is this modularity — no one makes these devices this way. The science happens on the tiny tissue model insert, which is sandwiched between two pieces of clear acrylic. This allows us to watch what’s happening on the tissue model insert in real time. Meanwhile, the outer shell’s clamshell design provides flexibility: if we’re studying lung tissue and we want to study the female reproductive tract, all we do is unscrew the outer shell and insert the proper tissue model that mimics the female reproductive tract and we’re off. We’ve done a lot of the engineering to make it very simple to operate and use, and adaptable to common lab tools that everyone has, to eliminate the need for financial investment in things like specialized clean rooms, incubators and pumps, etc., so the technology can be useful in regular labs or easily deployable to far-flung locations or countries. With a laser cutter and $500 worth of equipment, you could conceivably mass manufacture these things for maternal medicine in Africa, for example. Democratizing the technology so it is compatible and useful for even an inexperienced user aligns with the mission of my lab, which focuses on scaling the science and the innovation faster, instead of only a few specialized labs being a bottleneck to uncovering new mechanisms of disease and the development of therapies. We patented this modularity, the way to build these tiny microfluidic devices and the simplicity of how it's used as a tool set, through UD’s Office of Economic Innovation and Partnerships (OEIP). Q: How have you translated this work so far? Gleghorn: To date, we've taken this microfluidic system to nine different research labs across seven countries and four continents — including the United States, the United Kingdom, Australia, France, Belgium and South Africa. These labs are using our technology to study problems in women’s health and collecting data with it. We’re developing boot camps where researchers can come for two or three days to the University of Delaware, where we teach them how to use this device and they take some back with them. From a basic science perspective, there is high enthusiasm for the power of what it can tell you and its ease of use. As engineers, we think it's pretty cool that many other people are using our innovations for new discoveries. Q: What support and guidance have you received from the UD innovation ecosystem? Gleghorn: To do any of this work, you need partners that have various expertise and backgrounds. UD’s Office of Economic Innovation and Partnerships has built a strong team of professionals with expertise in different areas, such as how do you license or take something to patent, how do you make connections with the business community? OEIP is home to Delaware’s Small Business Development Center, which can help you think about business visibility in terms of startups. Horn Entrepreneurship has built out impressive programs for teaching students and faculty to think entrepreneurially and build mentor networks, while programs like the Institute for Engineering Driven Health and the NSF Accelerating Research Translation at UD provide gap funding to be able to do product development and to take the work from basic prototype to something that is more marketable. More broadly in Delaware is the Small Business Administration, the Delaware Innovation Space and regional grant programs and small accelerators to help Delaware innovators. Q: How have students in your lab benefited from engaging in innovation? Gleghorn: Undergraduate students in my lab have made hundreds of these devices at scale. We basically built a little manufacturing facility, so we have ways to sterilize them, track batches, etc. We call it “the foundry.” In other work, graduate students are engineering different components or working on specific system designs for various studies. The students see collaborators use these devices to discover new science and new discoveries. That's very rewarding as an engineer. Additionally, my lab focuses on building solutions that are useful in the clinic and commercially viable. As a result, we've had two grad students spin out companies related to the work we've been doing in the lab. Q: How has research translation positively impacted your work? Gleghorn: I started down this road maybe five years ago, seriously trying to think about how to translate our research findings. Being an entrepreneur, translating technology — it's a very different way to think about your work. And so that framework has really permeated most of the research that I do now and changed the way I think about problems. It has opened new opportunities for collaboration and for alternate sources of funding with companies. This has value in terms of taking the research that you're doing fundamentally and creating a measurable impact in the community, but it also diversifies your funding streams to work on important problems. And different viewpoints help you look at the work you do in new ways, challenging you to define the value proposition, the impact of your work.