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Media Training  Can You Afford NOT to Be Prepared When Reporters Come Calling? featured image

Media Training Can You Afford NOT to Be Prepared When Reporters Come Calling?

Want to see someone in a respected position of power throw away a career in all of about two minutes? Stephen Duckett was an expert in his field. Respected globally. Until this… Watch this exchange Duckett wasn’t prepared to deal with media. He paid a serious professional price and left a lesson for us all to learn from. In fact, his exchange is used by a lot of media trainers on exactly what not to do in a  crisis situation. As a former news producer, I remember scrambling to find an expert opinion or perspective when news was breaking. If a story required explanation and when it was beyond the grasp of even the brightest of reporters we needed the help of supporting sources.  They were critical in helping explain, validate, and ideally, break down just what was going on to our audiences at home. When an outbreak struck, we needed an epidemiologist. When a rare earthquake shook the region, the search for a seismologist was on. Finding the expert wasn’t usually the problem. We had local universities, colleges, and health care facilities within arm’s reach. However, finding an expert who could effectively speak on camera often was. Our goal was to keep people from turning the channel – so boring, highly technical speaking experts simply wouldn’t do it for us. When I worked in TV, we needed someone who could explain a complex subject, in layman’s terms, and in sound bites of about 15 seconds. It may not seem like much, but it is a lot to ask. Explaining high level content is not easy, but the reality is that your audience needs complex subjects explained in the simplest of ways. To do this right, it requires understanding the roles and goals of media and media training. Anyone who will be representing an organization, institution, or corporation needs some form of coaching. It’s a must-have requirement for most CEOs and politicians. Turn on your news at just about any hour of the day, and you can easily tell who has been properly prepared and trained and who hasn’t. It doesn’t happen organically. It takes work. It takes expert coaching. Media-friendly speakers bolster credibility and get noticed. In times of a crisis, a trained speaker may be the missing piece that can make or break a situation a reputation. Those who are not trained stick out—in a very bad way. They stammer, evade questions, ramble and are usually incoherent. If the task is mainly to describe a current situation, an untrained expert may ramble or speak hundreds of feet over the head of the average person. If there’s a crisis at hand—a tragedy, a scandal, a lawsuit or worse—an untrained speaker risks making a bad situation worse. Take a look back to July of 2013—an out-of-control train carrying crude oil exploded, destroying the downtown section of Lac Megantic, in Quebec, Canada. Thirty buildings were leveled, killing 47 people. In this small town, everybody knew somebody who was killed. Edward Burkhardt, president of Montreal, Maine & Atlantic Railway Inc. arrived shortly after the explosion. He was the near-perfect storm—an untrained, and likely uncoachable leader. He was clearly in distress, rattled, arrogant, and unprepared. He fixed blame at the worst possible time, blaming the train’s engineer and the local fire department. A journalist asked how much he was worth. A town is destroyed, the world is watching, close to four dozen people are dead, and his reply was, “I’m worth a lot less now than I was last week.” Proper media training and coaching would not have prevented the horrible tragedy, but knowing how to speak during such a high-stress situation and knowing what questions to expect might have mitigated the visceral reaction of residents, industry and government officials. As it stands, Edward Burkhardt and the company, no matter how successful either had been in the past, are now forever associated with that interview. Conway Fraser worked for the Canadian Broadcasting Corporation for almost 20 years. He’s a Gemini award-winning journalist who worked as a national reporter and investigative journalist. These days, he specializes in strategic and crisis communications as well as media coaching. Conway’s worked with some of Canada’s top corporate executives, academic leaders, and politicians. In both journalism and in PR, he has seen executives who have spent decades building a reputation only to have it destroyed in moments because they weren’t prepared to deal with the media. They’ve either never received media coaching or, Conway says, have taken mandatory training but were never further invested in. In other words, he says, they thought they didn’t need media training and were only taking it to appease the Board or ownership. “Proper media coaching isn’t just about knowing how to spew a main message, use effective body language or bridge away from challenging questions,” Conway says, “In my sessions I also teach my clients about the media, what their job is like, what a day is like for a reporter, what they need from you and how to respect their role. If anyone doubts the value of that, they’re playing with fire. Ask Stephen Duckett.” Natalie Duddridge is a reporter for NY1. I worked with Natalie years ago in Canada at the start of her career. Natalie’s talent as a journalist has taken her to Ottawa (Canada’s capital), Toronto, and most recently, New York. New York sits at the top (sorry L.A.) of media markets in the United States. It has a huge audience of about 10 million people and it is hands down the most competitive media game on the continent. Reporters in these markets never get to rest. They’re either chasing stories, or when they are covering a story they had better have an angle, source, or expert that the others do not. And when you are in a race with at least six other news outlets, standing out isn’t easy. Finding experts and having them ‘camera’ or ‘microphone’ ready is a must. As Natalie explained to me, getting an expert for a story is absolutely crucial. In a market as diverse as New York City, those experts can range from police to politicians, to health and education officials, to scientists and artists. Natalie also lent some great perspective on just how a reporter puts together a story and how your expert needs to know that news is also about storytelling and not just details. “Last week I did a story about the heroin epidemic plaguing the Borough of Staten Island,” Natalie explained. “We like to begin our stories with a human element, in this case a recovering drug addict. In addition to his personal opinions and insight about how to prevent and slow the opioid crisis in the region, we also reached out to the local Drug Rehabilitation Center and interviewed a doctor as well as a therapist. We also interviewed the Staten Island District Attorney about the work he’s doing with New York State Governor to get more dollars for a drug task force to do everything from put more money into preventative education, build rehab centers, add police, fund additional assistant district attorneys to process criminal cases.” If you were counting, you can see she spoke with three key experts on the subject of the story. Each was essential in the reporting process. “For this story we featured several different experts on varying opinions on how this current drug crisis should be dealt with. All of the facts, stats and data for this story were based on the officials and experts we contacted.” Being prepared and knowing what the reporter wants are also ideal elements in conveying the right message. For TV, short, smart, and to-the-point responses work best. “We need a 10 to 15 second sound bite that is ideally informative and clear, and in some cases entertaining,” Duddridge told me. “When I am making calls to experts, I essentially do a pre-interview over the phone to hear how clearly they can explain a topic. If they are great at breaking down studies and terms into focused ideas that are concise and fit into a two-minute story, our job as reporters is so much easier.” A win/win scenario. Your message is delivered, your institution and experts are promoted and the reporter files a great story. It all seems simple. But it’s not. It takes training and preparation. If you are going to offer up your experts for an interview, they need to be ready. Media training takes time, it costs money – but it’s an investment in your staff and your institution. As we learned from the example above, not knowing how to answer, interact, and respond to media can be devastating. Performing under pressure only succeeds with practice and training. If your experts are media trained the reward will always outweigh the risk. Here are a few tips: Get media trained – Use a professional media coach. It costs money, but the professional development, readiness, comfort, and ability to deliver will pay off ten-fold. Media-friendly experts get noticed – When your expert is on the news, people see them. They are representing your institution, so think about what this means for your credibility and recruiting potential. You never get a second chance at a first impression – An old, clichéd saying, but it’s true. A weak speaker who comes across poorly imprints a negative impression on viewers, peers and your institution as a whole. It’s amateur hour, and it doesn’t need to be. Friends for life – Once you prove yourself as a worthy and media-friendly source, the media will keep coming back. Experts who can provide journalists with the information, perspective, and sound bites they need are not only appreciated but noticed and remembered by all media. Once you have established yourself as a reliable source, expect the reporters to come calling time and time again. Dividends – Every story where your expert looks good is positive earned media. Getting on NBC, CBS, FOX or any other nightly newscast is a huge win for your Communications Department. It’s exposure, promotion, and advertising—and it’s free.  

Peter Evans profile photo
7 min. read
Fighting Red Tape To Win The Media Relations Speed Game featured image

Fighting Red Tape To Win The Media Relations Speed Game

It’s a situation that happens every day in the media relations world. A reporter calls and they need someone for an interview fast. This is how the scenario should play out: Step 1 - The media calls a communications officer with a simple request for information and an interview on a recently announced program. Step 2 – The communication officer identifies a suitable spokesperson. Step 3 – The reporter and spokesperson talk, arrange an interview -- and there is some excellent earned media and exposure for your institution. It sounds simple enough. But, not so fast. In reality, things often fall apart on step 3 and the process turns into something that borderlines on a Monty Python skit. Based on my experience and others I’ve consulted with – it often plays out something like this: The communications officer contacts the suitable spokesperson’s Manager to ensure it is okay they can speak to the expertise and subject matter they specialize in. Then, they have to loop in that manager with a Director and CEO to inform them of the media request and the plan. And then if the Director agrees, the CEO gets on board. Or perhaps the Director agrees only after checking with the CEO and agreeing to the spokesperson. Once that’s nailed down somehow…the CEO wonders if speaking points are required and will only proceed once the Manager and Director have signed off on them. After the speaking points are finally approved, speaking points and the media request are sent to the identified spokesperson. Then the communications officer (remember him or her?) responds to the media that they have found an expert and will arrange a time for interview. The communications officer has the Manager, Director, CEO and spokesperson each sign off on paper-generated Media Request Form for filing and safe records keeping. And, then…..finally……if the media hasn’t already gone elsewhere, the reporter and the spokesperson finally speak – about 18 steps later. It’s actually more steps than it takes to assemble my daughter’s bike or the average IKEA nightstand. It’s cumbersome, ineffective and costs the organization a lot of time in person power for something that doesn’t need to be this difficult. And the reality is … this spokesperson is a paid professional with a Master’s degree who was hired for the subject matter they specialize in. The media request was related to a media release issued by the organization. With a simple approval process and a pro-active approach to media, this could have been easier for everybody with an immediate turnaround and a positive outcome. Think this is a joke? It’s not. In fact, there’s a Communications Officer’s support group that meets every Thursday to share similar situations (I’m being cheeky). Media will appreciate that sensitive issues take time to respond to. In fact, a lot of media relish the thought the there are people scrambling to answer the tough questions. What drives media crazy is having to wait hours for what should be a simple, safe and low-risk reply. They likely already know the answer, they just need the expertise to lend it credibility and verification. (Photo courtesy: CBS Television Studios) So does your Communications Process need an institutional intervention? When you make it hard for media to get easy answers, they might start looking elsewhere. Odds are they will. Consider this: Do you have a grading system for media requests? Low-risk asks can be seen coming and responses pre-approved or left in the hands of your very competent staff. High risk asks mean approval and oversight. People will get that. As well, it will lend a tone of seriousness to the situation. Do you know the reporter or media outlet? A strong relationship needs faith on both sides. Known reporters and news outlets survive on reputation. Expect them to be professional and trust that they’ll get it right. Trust your Communications Team – Don’t Micro Manage Media relations isn’t a science – it’s an art where experience matters most. Communications Officers likely know the media and most come from a media background. They’ll know the angles, they scan the media and can likely predict the questions. Empower them to save you time and rely on their instincts. Too many Communications Officers ask “Why did you hire me?” when they aren’t trusted on the simplest of things. Most institutions have a rigorous vetting process – so why the worry? Didn’t you hire these people – rely on your staff and let them be accountable. Fewer steps saves time, reduces confusion and meets the need of a low-risk ask. Less micromanaging = more trust. Morale is a big deal in any workplace. So when the media calls, here’s my advice. Take a deep breath. Assess the risk. And arrange the interview as soon as possible and with as little maintenance and anxiety as possible. The media get the information they want, your institution gets the earned media and free exposure it wants and your Communications Team maintains a reputation as a group that can deliver content on deadline and ‘gets’ the information game. Remember – in today’s media – it’s all about speed. The easier you make it for media, the more the phone will ring.

Peter Evans profile photo
4 min. read
Baylor Study: Fear of Missing Out (FOMO) Plus Social Media Connections Can Equal Happiness featured image

Baylor Study: Fear of Missing Out (FOMO) Plus Social Media Connections Can Equal Happiness

FOMO – aka the “fear of missing out” – can have a positive impact on well-being when it leads to social media use that increases social connections, according to a new Baylor University study. James A. Roberts, Ph.D., The Ben H. Williams Professor of Marketing, and Meredith David, Ph.D., assistant professor of marketing in Baylor’s Hankamer School of Business, coauthored the study, “The Social Media Party: Fear of Missing Out (FOMO), Social Media Intensity, Connection, and Well-Being,” published in the International Journal of Human-Computer Interaction. Roberts and David collaborate often and are nationally recognized experts on the effects of technology and social media on relationships and well-being. For this collaboration, the researchers conducted two studies consisting of 565 college students from a large U.S. university to determine the effect FOMO has on social media use, social connection to others and psychological well-being. FOMO is defined in the study as apprehension that others might be having a rewarding experience from which one is absent. According to Roberts, approximately 75% of young adults struggle with FOMO. “The human need to belong is an innate drive that dictates much of our behavior. Social media capitalizes on this need to belong,” Roberts said. “Social media has a dual nature. It lets us interact with others, which is good, but it also exposes us to more social opportunities than we can take part in that fosters a sense of missing out and inadequacy.” The study found: FOMO is a significant predictor of subjective well-being, and social media intensity had a slight significant effect on well-being. Social media is an omnipresent conduit for attempting to make such connections. It is likely that FOMO encourages the use of social media to stay connected. From the first study of 107 college students, David and Roberts gathered data to measure FOMO, social media intensity and social connection. Although FOMO typically has a negative connotation on social interactions, the study showed that the fear of missing out can lead to greater feelings of social connection. “We found that FOMO might actually have a positive impact on social connection through its impact on social media intensity and attachment,” Roberts said. “FOMO drives our use of social media to connect socially with others. Being socially connected leads to happier people.” The second study of 458 college students used the same measures, but also included an assessment on subjective well-being (happiness). The study tested their complete conceptual model in which subjective well-being is an ultimate outcome of FOMO (through its impact on social media intensity and social connection). Roberts said that social media can be a positive resource to help those with FOMO create social interactions, if it is being used actively through online actions such as posting, liking and commenting. “The problem is that people often turn to social media but use it passively – such as creeping on people or viewing pages without interacting – which can then lead to lower levels of happiness because creeping does not foster social connection,” Roberts said. “FOMO can lead to happier people if it drives people to use social media to connect but not simply to ‘creep’ on others.” ABOUT THE STUDY AND AUTHORS James A. Roberts, Ph.D., The Ben H. Williams Professor of Marketing, and Meredith David, Ph.D., assistant professor of marketing in Baylor University’s Hankamer School of Business, coauthored the study, “The Social Media Party: Fear of Missing Out (FOMO), Social Media Intensity, Connection, and Well-Being,” which is published in the International Journal of Human-Computer Interaction. OTHER RESEARCH BY ROBERTS AND DAVID Cellphones Can Damage Romantic Relationships, Lead to Depression People Who Are “Phone Snubbed” By Others Often Turn To Their Own Phones, Social Media For Acceptance Bosses Who “Phone Snub” Their Employees Risk Losing Trust and Engagement When ‘Religiosity’ Competes with Materialism, Charitable Giving Takes a Hit ABOUT BAYLOR UNIVERSITY Baylor University is a private Christian University and a nationally ranked research institution. The University provides a vibrant campus community for more than 17,000 students by blending interdisciplinary research with an international reputation for educational excellence and a faculty commitment to teaching and scholarship. Chartered in 1845 by the Republic of Texas through the efforts of Baptist pioneers, Baylor is the oldest continually operating University in Texas. Located in Waco, Baylor welcomes students from all 50 states and more than 90 countries to study a broad range of degrees among its 12 nationally recognized academic divisions. ABOUT HANKAMER SCHOOL OF BUSINESS AT BAYLOR UNIVERSITY At Baylor University’s Hankamer School of Business, integrity stands shoulder-to-shoulder with analytic and strategic strengths. The School’s top-ranked programs combine rigorous classroom learning, hands-on experience in the real world, a solid foundation in Christian values and a global outlook. Making up approximately 25 percent of the University’s total enrollment, undergraduate students choose from 16 major areas of study. Graduate students choose from full-time, executive or online MBA or other specialized master’s programs, and Ph.D. programs in Information Systems, Entrepreneurship or Health Services Research. The Business School also has campuses located in Austin and Dallas, Texas. Visit www.baylor.edu/business and follow on Twitter at twitter.com/Baylor_Business. 

Meredith David, Ph.D. profile photoJames A. Roberts, Ph.D. profile photo
4 min. read
Climate Change: A Direct Threat to Older Adults featured image

Climate Change: A Direct Threat to Older Adults

Climate change will impact the health of all populations, but older adults are uniquely vulnerable because of the physiological changes of aging. More than half of older adults in the United States live in areas that disproportionately experience the effects of heat waves, forest fires, hurricanes and coastal flooding. Pennsylvania, New York, California, Florida and Texas account for the top five states where older adults are concentrated. Older adults who live in urban areas are vulnerable to heat island effect—the concentration and retention of heat in urban areas compared to rural areas—which places older residents in cities at increased risk of heat related illnesses and death. “Gerontological nurses need to be prepared to address the specific issues of older adults,” says Ruth McDermott-Levy, PhD, director of the Center for Global Health at Villanova University’s M. Louise Fitzpatrick College of Nursing. “We want to help nurses understand climate change and the need for specific interventions to support climate adaptation for the older adult population.” Climate change impacts require modifications in health plans for older adults. Prolonged heat will require greater needs for hydration, but the patient’s other conditions need to be considered as well. Elders with heart disease and renal failure will require astute nursing assessments to monitor the balance of hydration and electrolytes while not leading to fluid overload or electrolyte imbalances in the presence of extreme heat. With their research, practice and influence over policy, gerontological nurses are in an important position to be changemakers by measuring and documenting the harm and impact of climate change on older adults. They can advocate for measures that support older adults in disasters or extreme weather events. Nurse researchers can collaborate with climate scientists and policy makers to develop initiatives and programs that rely on climate and health evidence to support climate mitigation and adaptation for the older adult. “It is everyone’s responsibility to learn about climate change and to participate in slowing the trajectory of climate change,” Dr. McDermott-Levy says.

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2 min. read
Impact of Record-Breaking Floods in Venice featured image

Impact of Record-Breaking Floods in Venice

Over the last week, Venice, Italy, has been hit with historic flooding. On Sunday, November 17, water levels topped 1.5 meters for the third time since last Tuesday’s 1.87-meter flood, which marked the worst in more than half a century.   Venice’s mayor declared a state of emergency and has estimated the flooding damage at hundreds of millions of euros. The flooding is putting some of Venice’s most historic architecture at risk and threatening some of the city’s cultural marvels and priceless artwork.   The situation has also renewed the debates around the underwater barrier system—the MOSE flood defense project—that has been under construction for more than 16 years and is not yet operational despite five billion euros of public funding.   Luca Cottini, PhD, an associate professor at Villanova University, is a scholar of Italian culture. He recently discussed some of the issues currently facing Venice.   “The flooding in Venice makes visible once again not just the fragility of Italian beauty and the vulnerability of Italy’s geography, but also the inadequacy of Italian politics in the prevention and response to natural disasters,” said Dr. Cottini.   Dr. Cottini also addressed the city’s tourism and how tourists view the floods.   “The situation also illustrates the cynical nature of modern-day global tourism, observing high waters more as an attraction than a tragic event impacting invaluable monuments and the lives of many peoples,” he said.  

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1 min. read
U.S. economy continues to expand, but at a slower pace, reaching about 2 percent growth in 2020 featured image

U.S. economy continues to expand, but at a slower pace, reaching about 2 percent growth in 2020

INDIANAPOLIS -- The U.S. economy will continue to expand for a 12th consecutive year in 2020, but by only about 2 percent and struggling to remain at that level by year's end. Indiana's economic output will be more anemic, growing at a rate of about 1.25 percent, according to a forecast released today by the Indiana University Kelley School of Business. Over the past year, political dysfunction and international trade friction have disrupted supply chains and eroded both consumer and business confidence. U.S. employment has grown during 2019 but will decelerate throughout 2020, well short of 150,000 jobs per month and possibly to about 100,000 by year's end. A tight labor market will continue to be an issue for many companies.   "The total number of job openings in the economy peaked in late 2018," said Bill Witte, associate professor emeritus of economics at IU. "Average hours worked have been flat over the past year, and auto sales have been flat for nearly two years. Given the reliance of the U.S. economy on consumer spending, these are disturbing signs. But they are vague signs, and not enough to convince us that the end of the expansion is in sight.   "We expect that growth will be weaker than in the past two years, and this outlook is likely a best-case outcome," he added. "There is massive uncertainty in the current situation."   The Kelley School presented its forecast this morning to Indianapolis community and business leaders at IUPUI. The Business Outlook Tour panel also will present national, state and local economic forecasts in seven other cities across the state through Nov. 20.   Indiana's more meager economic growth expected in 2020 can largely be attributed to the outsized presence of manufacturing and particularly tight labor markets, said Ryan Brewer, associate professor of finance at Indiana University-Purdue University Columbus and author of the panel's Indiana forecast. Manufacturing contracts more rapidly versus other areas of the economy, and tight labor markets limit employers' capacity to grow, he said.  Expectations about business investment have fallen short, and corporations have been buying back stock instead of making capital investments. The trade war with China and slowing global expansion have also affected state manufacturers.  The world is about to record its slowest economic growth since the financial crisis of 2009. Next year, global growth is projected at 3.4 percent, with downside risks continuing to build. China and the European Union each face structural issues amid tariffs imposed by the United States. Brexit remains unresolved.   Recent data from the Institute for Supply Management showed that manufacturing activity has slowed to its lowest rate since the beginning of the Great Recession. Indiana has sought to diversify its economy in recent decades, but manufacturing output represents nearly 28 percent of gross state product. Indiana continues to lead the nation in manufacturing employment, with more than 17 percent of its jobs in that sector.   "Constrained by a historically tight labor market, Indiana is expected to experience slow growth in jobs and gross output, along with the possibility for continued rising wages," Brewer said. "With fewer and fewer available people to hire, tightness of the Indiana labor markets will serve as a drag to output and employment growth."   The outlook for the Indianapolis-Carmel-Anderson metropolitan statistical area is slightly better, with expected growth between 1.5 and 2 percent.   "Indianapolis continues to draw in talent and investment that should help it exceed the overall state level of growth," said Kyle Anderson, clinical assistant professor of business economics. "However, there is risk that weakness in the broader economy, and especially weakness in manufacturing, could make this forecast too optimistic."   Other highlights from the forecast:   The national and state unemployment rates will hold steady. The nation's rate could be below 4 percent by year's end, and the state will stay at or below full employment through 2020.  Inflation will rise and end 2020 close to the Federal Reserve's 2 percent target. The stock market will struggle to get average returns with headwinds from trade, supply chain disruption and policy uncertainty. Earnings continue to exceed expectations, yet lack of definitive trade consensus continues to drive headwinds. Interest rates will remain low. The 10-year Treasury rate should stay below 2 percent and mortgages below 4 percent. Speculative grade bond yields have been rising, indicating increased risk of insolvency for marginal firms. Entry-level wage growth could cause costs to rise, earnings to fall and growth to stagnate for firms heading into 2020. Energy prices will be relatively stable, with average prices similar to those in 2019. Business investment will remain weak, although a little improved from this year. Housing will achieve a meager increase, ending two years of negative growth. Government spending will grow, but much more slowly than the past year, as the impact of the 2018 budget deal ends. The starting point for the forecast is an econometric model of the United States, developed by IU's Center for Econometric Model Research, which analyzes numerous statistics to develop a national forecast for the coming year. A similar econometric model of Indiana provides a corresponding forecast for the state economy based on the national forecast plus data specific to Indiana. A select panel of Kelley faculty members, led by Indiana Business Research Center co-director Timothy Slaper, then adjusts the forecast to reflect additional insights it has on the economic situation.   A detailed report on the outlook for 2020 will be published in the winter issue of the Indiana Business Review, available online in December. In addition to predictions about the nation, state and Indianapolis, it also will include forecasts for other Indiana cities and key economic sectors. Presenting the forecast at the Indianapolis Business Outlook Tour event were Phil T. Powell, associate dean of Kelley academic programs at Indianapolis and clinical associate professor of business economics and public policy; Cathy Bonser-Neal, associate professor of finance; and Anderson.

At VCU, engineering and pharmacy join forces to make inhaled medications more effective for infants and children featured image

At VCU, engineering and pharmacy join forces to make inhaled medications more effective for infants and children

Pharmaceutical aerosols are painless, fast-acting and less likely to cause side effects than medicines delivered via pills or injections. Yet inhaled therapies are often avoided because of the challenges associated with targeting how aerosol particles are deposited within the lung. “Current inhalers produce fairly large particles, so approximately 90 percent of the medication gets lost in the mouth and throat. It’s swallowed and wasted. This prevents many medications from being delivered through the inhalation route, even though there are a number of advantages to be gained, such as improved efficacy and reduced side effects,” said Worth Longest, Ph.D., the Louis S. and Ruth S. Harris Exceptional Scholar Professor in the Department of Mechanical and Nuclear Engineering in the VCU College of Engineering. Simply making the particles smaller isn’t a solution. “The problem with making the particles smaller is that they go in really well — but they also come straight back out during exhalation,” said Michael Hindle, Ph.D., the Peter R. Byron Distinguished Professor in the VCU School of Pharmacy. With three National Institutes of Health R01 grants totaling more than $7 million, Longest and Hindle are applying a combined engineering and pharmaceutical approach to make inhaled medications more effective and available. In “High-Efficiency Aerosol Delivery Using the Excipient Enhanced Growth Concept: A Human Proof of Concept Study,” Longest and Hindle have created a novel platform that produces particles that are tiny when they enter the lungs — but grow in size as they travel down the warm, humid airways. This platform comprises a device that uses a mixer-heater to produce tiny particles, about one-fifth the size of those from conventional inhalers. With this delivery concept, a pharmaceutical powder or liquid is enhanced with a hygroscopic excipient, essentially a substance that attracts water. “Your lungs are full of water,” Hindle said. “So if you put something inside your lungs that likes water, it’s going to swell and grow in size and not be expelled.” Using sodium chloride — salt — as the hygroscopic excipient, they have tested their system in vitro. The results have been promising. “We’ve flipped the needle,” Longest said. “Previously, only 10 percent of the initial dose would reach the lung, and that 10 percent was poorly targeted within different lung regions. With our approach, you can get 90 percent in and distribute that 90 percent evenly, or target a specific lung region.” The researchers will begin testing their method on adults in two human proof-of-concept trials beginning in late 2019 and early 2020. In two separate, but related, NIH studies, Longest and Hindle are adapting this concept for patients ranging in age from newborn to six. Each project proposes a device approximately the size of a lipstick tube that contains a pediatric formulation (liquid or powder) enhanced with a hygroscopic excipient. There are currently no inhalers on the market specifically designed for children or infants, even though their inhaling patterns and volumes differ from those of adults. Pediatric patients therefore must use adult-sized devices. One study focuses on targeted lung delivery of the antibiotic tobramycin to children with cystic fibrosis, a population prone to respiratory infection because of overproduction of mucus in the lungs. Pediatric cystic fibrosis patients with lung infections usually receive the medication via, 20-minute nebulizer treatments daily, sometimes up to four per day. Longest and Hindle’s proposed alternative is a pediatric dry powder inhaler that is fast and easy to use. Because its particles are engineered to reach the deep lung, it is expected to eradicate infection more efficiently because there is less risk of resistant strains of bacteria forming in undertreated regions of the lung. The other study focuses on delivery of surfactant aerosols to premature infants. Surfactant is a substance found in healthy lungs that keeps the tissue supple enough to expand and contract properly. The respiratory system is among the last to develop in utero, so in newborns and preemies, this substance is sometimes not fully developed — or not present at all. When these infants experience severe respiratory distress, the current protocol is to intubate and administer large doses of liquid surfactant to the lung by way of the throat. This highly invasive and potentially dangerous procedure causes distress and blood pressure fluctuations. In this third NIH-funded study, the researchers are also developing a tiny, small volume nebulizer and a dry powder inhaler for efficient, noninvasive respiratory support for infants.

3 min. read
Gene therapy and the next frontier of medicine featured image

Gene therapy and the next frontier of medicine

Genetic testing today is mainstream, marketing to consumers who want to know where in Europe they came from or what types of hereditary diseases they could develop. For around $200 you can trace your family tree to learn your origins or identify genetic abnormalities that could signal disease. James Dahlman, assistant professor in the College of Engineering’s biomedical engineering department, specializes in genetics and believes these genotyping services can be helpful, as long as they are used responsibly. “If you’re going to start making medical predictions, you have to be careful,” said Dahlman. “Most people are not equipped to interpret statistics correctly, which can lead to negative predicting and ethical dilemmas. In a few years, genetic counselors will be in high demand so folks can make better decisions about their health.” Dahlman is fascinated by genetics, citing gene therapy as the most interesting field in the world. And it’s a field that he is revolutionizing through his research. Gene therapy is an experimental technique that uses genes to treat or prevent diseases, including hemophilia, Parkinson’s, cancer and HIV. It can help manage a number of diseases by leveraging genes instead of drugs or surgery. Although gene therapy shows promise, there are still risks involved, including unwanted immune system reactions or the risk of the wrong cells being targeted. That’s where Dahlman’s research comes in. Dahlman’s lab focuses on drug delivery vehicles, which are nanoparticles. The nanoparticle delivers gene therapies to the right place in the body to fight disease. It’s critical that the gene therapies only target the unhealthy cells to avoid damaging healthy ones. Dahlman is laser focused on ensuring the nanoparticles know what paths to take to reach the correct organ to start the healing process. “The issue with genetically-engineered drugs is that they don’t work unless they get to the right cell in the body,” said Dahlman. “You can have the world’s best genetic drug that's going to fix a tumor or eradicate plaque, but it’s not going to be effective unless it travels to the right organ. In my lab, we design different nanoparticles to deliver the genetically-engineered drugs to the correct location.” The field of genetic therapy is fascinating – and if you are a journalist looking to cover this topic or have questions for upcoming stories – let our experts help. James Dahlman is an Assistant Professor in the Georgia Tech BME Department. He is an expert in the area of biomedical engineering and uses molecular biology to rationally design the genetic drugs he delivers. This research is redefining the field of genetic therapy. Dr. Dahlman is available to speak with media – simply click on his icon to arrange an interview.

James Dahlman profile photo
2 min. read
MEDIA RELEASE: Driving high? New research shows many Ontarians get behind the wheel too soon after consuming cannabis featured image

MEDIA RELEASE: Driving high? New research shows many Ontarians get behind the wheel too soon after consuming cannabis

As we approach the first anniversary of the legalization of cannabis and prepare for the introduction of legal edibles, CAA South Central Ontario (CAA SCO) is releasing new data that suggests that the dangers of cannabis-impaired driving are misunderstood by many. It shows that approximately 1.2 million Ontario drivers have, at some point, driven high after consuming cannabis. Seventy-two per cent report waiting three hours or less to get behind the wheel, with 27 per cent feeling very or somewhat high when they did. “We know that driving under the influence of cannabis affects your ability to drive safely and increases your risk of getting into a crash,” said Teresa Di Felice, assistant vice-president of government and community relations at CAA SCO. “The research has shown us that young Canadians are more at risk of a vehicle crash even five hours after inhaling cannabis.” The research also shows that over half of Ontario drivers who use cannabis are “poly-users,” meaning they typically pair cannabis with another substance. Alcohol is by far the most common substance paired with cannabis. Cannabis-infused edibles are another option that may further complicate matters when it comes to drug-impaired driving. Twelve per cent of non-users indicated they were very or somewhat likely to try edible cannabis products after it becomes legal. “It is crucial to continue to explore and understand what impact the legalization of edibles may have on Ontario’s roads. If Ontarians choose to consume edibles, they should be aware of its delayed psychoactive effects and the impact on their ability to drive,” said Di Felice. CAA’s focus is to ensure that road safety, public education and enforcement remain at the forefront of the management of cannabis legalization. The statistically representative study, commissioned by CAA and conducted by Dig Insights in late June 2019, surveyed 1,510 Ontarian between the ages of 19 and 70 who have a valid driver’s license. ��                           

Teresa Di Felice profile photo
2 min. read
October is Breast Cancer Awareness Month – Let our experts help with your coverage featured image

October is Breast Cancer Awareness Month – Let our experts help with your coverage

October is Breast Cancer Awareness Month and if you are a reporter looking to know more or considering covering this topic, here are a few key facts to get started according to Breastcancer.org: About 1 in 8 U.S. women (about 12%) will develop invasive breast cancer over the course of her lifetime.  In 2019, an estimated 268,600 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with 62,930 new cases of non-invasive (in situ) breast cancer.  About 2,670 new cases of invasive breast cancer are expected to be diagnosed in men in 2019. A man’s lifetime risk of breast cancer is about 1 in 883. About 41,760 women in the U.S. are expected to die in 2019 from breast cancer, though death rates have been decreasing since 1989. For women in the U.S., breast cancer death rates are higher than those for any other cancer, besides lung cancer.  Besides skin cancer, breast cancer is the most commonly diagnosed cancer among American women. In 2019, it's estimated that about 30% of newly diagnosed cancers in women will be breast cancers.  In women under 45, breast cancer is more common in African-American women than white women. A woman’s risk of breast cancer nearly doubles if she has a first-degree relative (mother, sister, daughter) who has been diagnosed with breast cancer. Less than 15% of women who get breast cancer have a family member diagnosed with it. At Augusta University, we have leading experts who can help with any of your questions, assist with your coverage and ensure your story has all the facts and details it requires to be a compelling and effective piece. Dr. Alicia Vinyard is a Board-Certified General Surgeon and Fellowship Trained Breast Surgical Oncologist at the Georgia Cancer Center and Medical College of Georgia at Augusta University. Dr. Vinyard is also an expert in breast cancer, cancer surgery and cancer survivorship. She is available to speak to media about Breast Cancer Awareness Month – simply click on her icon to arrange an interview.

Alicia Arnold, DO profile photo
2 min. read