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Meet the astrobiologist and her students who are searching for life on Mars
By Emma Richards, University of Florida From a young age, Amy Williams wondered if life existed beyond Earth amidst the dark abyss of space, stars and planets — a curiosity that years later landed her a career researching and exploring Mars. Williams, an assistant professor of geology and an astrobiologist at the University of Florida, works as a participating scientist on the Perseverance and Curiosity Rover Science Teams and previously served as a postdoctoral research associate at NASA’s Goddard Space Flight Center. As an astrobiologist and geobiologist, she uses techniques from geology, microbiology and chemistry to search for life beyond Earth. “Even as a little kid watching meteor showers with my family, I wondered if there was someone out there in the stars looking back at Earth.” “Even as a little kid watching meteor showers with my family, I wondered if there was someone out there in the stars looking back at Earth,” she said in an episode of the From Florida podcast. “It’s been a passion of mine my whole career and now it’s the most amazing opportunity to serve on both of the active Mars rover missions.” Williams’ journey to Mars began as a graduate student when a research professor gave her the opportunity to work on the NASA Curiosity mission. From there, Williams built her way up and is now a participating scientist working on day-to-day rover operations. Williams also is opening doors for graduate students at UF to work on Mars research, helping upcoming generation of scientists follow her path. She is specifically interested in involving women and underrepresented groups in her work. Based on her research, Williams said life on Mars, if found, will likely look less like Marvin the Martian and more like microbial life similar to bacteria on Earth. Curiosity landed on Mars in 2012 and Perseverance landed in 2021. The rovers are searching for potential life on Mars by going to habitable environments and searching for evidence of water and essential elements that could supported such life forms. Curiosity has spent nearly its entire mission exploring a large five-kilometer-tall mountain in Gale Crater known as Mount Sharp. The scientists can see Mars’ history and climate based on changes in the chemistry and sediments of the mountain. As for Perseverance, the rover is exploring Jezero Crater, with emphasis on its delta, a geologic deposit that is formed when water from a river flows into a lake. Perseverance will help collect rock and sediment samples from Mars that will be the first brought back to Earth. NASA is also working on a program to eventually send humans to Mars, which will likely take many decades; the first stage in the project will be returning humans to the Moon. “But in the meanwhile, these robots, these rovers that we send to the red planet, they are our proxy,” Williams said. “And looking through the robot rover’s eyes, the images that are returned to us, I recognize this is the closest I will ever be to standing on Mars and looking up at these beautiful geological units, looking up at an alien world that’s so familiar because the tenets of geology apply on Mars, the same as they do on Earth.” To hear more about the Amy Williams' Mars research, listen to the episode on From Florida at this link. Listen to other episodes in the "From Florida" series at this link. To learn more about her work, watch this video featuring Professor Williams:
Antimicrobial resistance now causes more deaths than HIV/AIDS and malaria worldwide – new study
Antimicrobial resistance is spreading rapidly worldwide, and has even been likened to the next pandemic – one that many people may not even be aware is happening. A recent paper, published in Lancet, has revealed that antimicrobial resistant infections caused 1.27 millions deaths and were associated with 4.95 million deaths in 2019. This is greater than the number of people who died from HIV/AIDS and malaria that year combined. Antimicobial resistance happens when infection-causing microbes (such as bacteria, viruses or fungi) evolve to become resistant to the drug designed to kill them. This means than an antibiotic will no longer work to treat that infection anymore. The new findings makes it clear that antimicrobial resistance is progressing faster than the previous worst-case scenario estimates – which is of concern for everyone. The simple fact is that we’re running out of antibiotics that work. This could mean everyday bacterial infections become life-threatening again. While antimicrobial resistance has been a problem since penicillin was discovered in 1928, our continued exposure to antibiotics has enabled bacteria and other pathogens to evolve powerful resistance. In some cases, these microbes are resistant even to multiple different drugs. This latest study now shows the current scale of this problem globally – and the harm it’s causing. Global problem The study involved 204 countries around the world, looking at data from 471 million individual patient records. By looking at deaths due to and associated with antimicrobial resistance, the team was then able to estimate the impact antimicrobial resistance had in each country. Antimicrobial resistance was directly responsible for an estimated 1.27 million deaths worldwide and was associated with an estimated 4.95 millions deaths. In comparison, HIV/AIDS and malaria were estimated to have caused 860,000 and 640,000 deaths respectively the same year. The researchers also found that low- and middle-income countries were worst hit by antimicrobial resistance – although higher income countries also face alarmingly high levels. They also found that of the 23 different types of bacteria studied, drug resistance in only six types of bacteria contributed to 3.57 million deaths. The report also shows that 70% of deaths that resulted from antimicrobial resistance were caused by resistance to antibiotics often considered the first line of defence against severe infections. These included beta-lactams and fluoroquinolones, which are commonly prescribed for many infections, such as urinary tract, upper- and lower-respiratory and bone and joint infections. This study highlights a very clear message that global antimicrobial resistance could make everyday bacterial infections untreatable. By some estimates, antimicrobial resistance could cause 10 million deaths per year by 2050. This would overtake cancer as a leading cause of death worldwide. Next pandemic Bacteria can develop antimicrobial resistance in a number of ways. First, bacteria develop antimicrobial resistance naturally. It’s part of the normal push and pull observed throughout the natural world. As we get stronger, bacteria will get stronger too. It’s part of our co-evolution with bacteria – they’re just quicker at evolving than we are, partly because they replicate faster and get more genetic mutations than we do. But the way we use antibiotics can also cause resistance. For example, one common cause is if people fail to complete a course of antibiotics. Although people may feel better a few days after starting antibiotics, not all bacteria are made equal. Some may be slower to be affected by the antibiotic than others. This means that if you stop taking the antibiotic early, the bacteria that were initially able to avoid the effect of the antibiotics will be able to multiply, thus passing their resistance on. Likewise, taking antibiotics unnecessarily can help bacteria to evolve resistance to antibiotics faster. This is why it’s important not to take antibiotics unless they’re prescribed, and to only use them for the infection they’re prescribed for. Resistance can also be spread from person to person. For example, if someone who has antibiotic-resistant bacteria in their nose sneezes or coughs, it may be spread to people nearby. Research also shows that antimicrobial resistance can be spread through the environment, such as in unclean drinking water. The causes driving this global antimicrobial resistance crisis are complex. Everything from how we take antibiotics to environmental pollution with antimicrobial chemicals, use of antibiotics in agriculture and even preservatives in our shampoo and toothpaste are all contributing to resistance. This is why a global, unified effort will be needed to make a difference. Urgent change is needed in many industries to slow the spread of antimicrobial resistance. Of the greatest importance is using the antibiotics we have smarter. Combination therapy could hold the answer to slowing down antimicrobial resistance. This involves using several drugs in combination, rather than one drug on its own – making it more difficult for bacteria to evolve resistance, while still successfully treating an infection. The next pandemic is already here – so further investment in research that looks at how we can stop this problem will be key.
How potato milk measures up against other plant-based milk alternatives
It seems like almost every plant-based food is being turned into “milk” these days, the latest being potato milk. It’s not surprising that potatoes have been chosen to be the latest plant-based milk. After all, potatoes have many health benefits because they’re full of important vitamins and nutrients. But how do they measure up to other popular plant-based milks? Protein content No matter the type of plant-based milk, they only contain a fraction of the ingredient they’re derived from. For example, only 10% of the volume of a carton of rice or oat milk comes from these grains. Soy drinks contain between 5%-8% of the actual soya bean, and almond milks contain as little as 2% of the actual nut. Since coconut uses the cream or milk from the fruit, it contains between 5%-13%, depending on how creamy the product is. And based on the current potato milk products out there, a one-litre carton only contains around 60g of an actual potato – a small potato. The problem with this is that these milks now contain far fewer vitamins and nutrients than the raw ingredient would. This may make them less nutritious than they would be if you ate the ingredient whole. Take protein, for example. Ingredients like almonds are naturally great sources of protein containing over 20g of protein per 100g of almonds. But after processing, 100 millilitres of almond milk only contains around one gram of protein. This is actually the same amount of protein you’d find in the same amount of oat milk – even though oats contain far less protein (13.5g per 100g). Soya milk is better as it contains more of the soya beans compared with almond milk. In fact, soya milk gives around 3-3.5g of protein per 100ml. This is about as much protein as you get in the same amount of cow’s milk. And like cow’s milk, soya milk contains essential amino acids which our body isn’t able to naturally produce. Amino acids are important as they ensure our body works properly – such as by helping our muscles keep moving. Potatoes are already low in protein. This means that after processing, potato milk contains about as much protein as coconut and rice milk – less than 0.5g of protein per 100ml. But some potato milk brands do supplement with pea protein, which makes a 100ml serving have around 1.3g of protein. So if you’re choosing your plant-based milk for protein content, you might be best sticking with soya or almond milk over potato milk. Added sugars As with cow’s milk, plant-based milks can also contain added sugars. We are encouraged to limit our added sugar intake to no more than five to six teaspoons a day. This is because eating too much sugar is linked to an increased risk of obesity as well as tooth decay. But given many products sell both sweetened and unsweetened versions, it’s easier for someone to buy a product that contains no sugar. Sweetened potato milk contains about 1.8g of sugar per 100ml. This is a little less than other plant-based milks which contain around 2 to 3.5g of added sugar per 100ml. So in this category, potato milk comes out on top. Although some plant-based milk uses natural sugars from fruit, this is still considered added sugar and should be limited. Fat content Since potatoes are naturally low in fat, potato milk would have a texture more akin to water. This is why extra fat is added to it. A similar thing is done with rice and oat milk, where oil (such as sunflower oil) is added. This brings the fat content up so that it’s closer to semi-skimmed milk (about 1.5g per 100ml). For potato milk, rapeseed oil is added. Almond and soya both tend to contain fat already, so no additional oil is added. This means that compared with other plant-based milks, potato milk is higher in monounsaturated fats, which are thought to be better for your heart. They’re also lower in saturated fats than cow’s milk, which is thought to be less healthy for our hearts. A “barista version” of milk alternatives needs to contain a combination of both protein and fat in order for the milk to foam, so have slightly more fat added to them. Added vitamins When it comes to vitamins and minerals, many plant-based milks have these added to them, as they simply don’t have as many as cow’s milk naturally does. Vitamins like riboflavin, B12 and D alongside calcium are added to potato milks. The same is also true for other plant-based milks – although organic versions may not have added vitamins often due to organic food rules and trying to keep the label clean of additives. As many of us struggle to get enough vitamin D – which is essential for healthy bones and immune system – and many vegans and vegetarians can have low B12 levels (which is needed to keep our blood cells and nerves healthy) going for milk alternatives with these added vitamins and minerals can be a good idea. Potato milk is yet another option for those wanting an alternative to cow’s milk or other plant-based milks, or those looking for a more environmentally friendly milk product. Nutritionally, it may not contain the protein of soya milk, but many products are fortified, so they still contain important vitamins and minerals. But since it contains several refined ingredients, such as oils and protein isolates (proteins extracted from foods), it may technically count as an ultra-processed food. There are some concerns about ultra-processed foods, which have been linked to chronic disease – so it is yet to be seen whether potato milk has similar risks.
Tony Cocker is senior independent director at SSE plc and chair of Infinis Energy Management He was CEO and chair of E.ON UK from 2011 to 2017, and was also chair and non-executive director at various organisations, including Affinity Water Ltd, EIC, and the Energy & Utilities Industrial Partnership Professor Cocker will work within Aston University’s College of Business and Social Sciences focussing on energy operations, innovations and sustainability. Independent Director at SSE and Infinis and former CEO of E.ON UK has joined Aston University as a Visiting Professor within the College of Business and Social Sciences. Tony Cocker will work closely with the director of the Centre for Circular Economy and Advanced Sustainability (CEAS), Dr Luciano Batista, and the director of the Energy and Bioproducts Research Institute (EBRI), Professor Patricia Thornley, to develop connections between Aston University and the energy industry over the next three years. In the next 12 months, Tony will engage with undergraduate and postgraduate students across Aston Business School and with researchers at CEAS and EBRI. He will support the development the CEAS Advisory Board, give programme specific and public talks, and participate in networking events that will appeal to a wide range of key stakeholders such as students, academics, industry, and government partners across Aston University. The potential to support Aston student placements opportunities and mentoring for students will also feature as part of Tony’s engagement. Professor Cocker will also work with colleagues at Aston Business School and EBRI to expand research connections in common areas of interest associated with energy innovations, business strategies and sustainability. Professor Cocker said: “I am excited and motivated to join Aston University as a visiting professor. I am looking forward to supporting the teaching and research agenda of the university, capitalising on the knowledge and industry connections I have built over the years in the energy sector and related industries.” Dr Luciano Batista, head of CEAS at Aston Business School, said: “I am looking forward to working with Tony. His professional experience and vast industrial connections will add considerable value to the teaching activities and research collaborations we develop across key programmes and research projects in the business school. It is a great privilege to have an experienced business leader in the faculty team at Aston Business School. This well-deserved appointment recognises the notable contribution Tony has made, and continues to make, to the industry over the years.” Professor Patricia Thornley, director of the Energy and Bioproducts Research Institute (EBRI), said: “Tony brings a wealth of knowledge and experience which will be really valuable to Aston University. We already have a long list of areas where we will be working together so that our students can benefit from his expertise and I look forward to working with him to expand the relevance of our research and engagement, particularly in energy”.
Aston University has teamed up with biotechnology company Biocleave Ltd in a new knowledge transfer partnership (KTP) to develop the company’s capacity to produce membrane-associated proteins on a competitive commercial scale. The partnership will see Aston University’s world-leading expertise provide next-level solutions to a complex problem and provide exciting breakthroughs from both commercial and scientific standpoints. A knowledge transfer partnership (KTP) is a three-way collaboration between a business, an academic partner and a highly qualified graduate, known as a KTP associate. The UK-wide programme helps businesses to improve their competitiveness and productivity through the better use of knowledge, technology and skills. Aston University is the leading KTP provider within the Midlands. Biocleave Ltd produces ‘Research Use Only’ (RUO) proteins. These are used widely in industry and academia to study and develop diagnostics and disease treatments. The process of manufacturing these proteins is known as ‘expression’, requiring host cells to produce them. The company is the first to engineer the non-pathogenic microbe Clostridia as a recombinant protein expression host, enabling them to overcome the typical expression challenges of production host toxicity and costly development cycles. Initial trials have demonstrated advantages to making membrane-associated proteins in Clostridia compared with established production systems. However, these proteins are associated with the fatty membrane that surrounds a cell and are not soluble in water. While Biocleave has well-established proprietary technology for manipulating the microbes, they want to extend their expertise for purifying these challenging membrane proteins, essential to commercialising their production. The Aston University team will be led by Dr Alan Goddard, senior lecturer in biochemistry in the School of Biosciences and founding member of Aston Membrane Proteins and Lipids (AMPL). Dr Goddard’s research focuses on the application of membrane biology to industrially relevant problems. He has nearly 20 years' experience working with membranes and their integral proteins. Dr Goddard will be joined by Professor Roslyn Bill, associate dean (research) for the College of Health and Life Sciences and director of AMPL. Professor Bill’s research focuses on the purification and characterisation of membrane proteins and she has published extensively on yeast as a recombinant expression host. Commenting on the project, Dr Goddard said: “This is a really exciting opportunity to leverage the decades of research experience Professor Bill and I have with expressing and purifying membrane proteins. It will allow Biocleave to enter new markets, many of which are important for drug development and healthcare. Hopefully, the products we make will have positive benefits not only for Biocleave’s customers but also wider society.” Dr Liz Jenkinson, chief executive of Biocleave Ltd, said: “We’ve made great progress in establishing the technology to work with Clostridia, a promising host, and although we’re constantly learning, so much is still unknown about the clostridial membrane. Through this KTP partnership with Aston University, we’re excited to develop the skills of our staff and expand our commercial offering to extend our range of RUO protein targets.” Because the Clostridial membrane adds a new level of complexity, successfully developing the required tools internally to resolve these issues, without input from experts, would take considerable time.
Georgia Southern University has established a new research and outreach center, the Institute for Water and Health, to investigate the complex interactions between water and human activities, and protect and restore public health in a changing environment. As part of the University’s focus on public impact research, the center will foster collaboration among scientists, government agencies, industry, nonprofit organizations and communities. Coastal Georgia is the perfect location for such an institute to conduct interdisciplinary research because it lies at the intersection of many social, economic and ecological issues. The center supports the region through research, workforce training for students, and actively involving communities in water resource management decision-making process, said Asli Aslan, Ph.D., associate professor in Georgia Southern’s Jiann-Ping Hsu College of Public Health Department of Biostatistics, Epidemiology and Environmental Health Sciences. Now also director of the Institute for Water and Health, Aslan is a water microbiologist, and her research program bridges ecosystem and human health. She has ongoing funded projects on tracking sources of water pollution and assessing health risks associated with exposure to chemical and microbial contaminants. She works with local communities and nonprofit organizations to encourage water stewardship behaviors. Aslan has served in various federal and state agencies and organizations as an adviser, reviewer, scientific committee member and affiliated faculty. She is also the founder and currently the co-chair of the Water and Health Committee of the American Public Health Association. “We want to create a nationally recognized institution that provides meaningful solutions for community needs,” said Aslan. “Our immediate plan is to develop a coalition with all stakeholders in the region to address issues related to increased water demand, impact of sea-level rise on water resources, and potential emerging contaminants in our urban and rural water infrastructure. We are in the process of establishing a community advisory group consisting of scientists from academic institutions, representatives from local and state governments, community leaders, non-profit organizations and businesses to identify and prioritize community needs in water research and education.” For example, she said, although one in every six households in Georgia has a private well, few residents realize any water testing, treatment or well maintenance is the sole responsibility of the property owner as per the Safe Drinking Water Act. Aslan said the Institute for Water and Health will work with the homeowners to help them recognize potential risks and provide solutions that will keep families safe in the long term. “We also look at sources of contaminants using state-of-the-art-methods. And if you know where the pollution is coming from precisely, it’s easier to go fix that problem once and for all, which has a direct impact on the decision-making process to protect water resources.” she said. These new techniques allow researchers with the institute to provide test results within a few hours, which helps end-users to be informed the same day instead of days where most water testing methods currently take about 48 hours. The implications of these methods are broad, as they can be used to identify pathogens in storm water or in household drinking water pipes; assess how new sustainable water treatment technologies efficiently remove contaminants, or provide same-day results for recreational beach monitoring. “We can do all this fancy research in the lab, but it will be very important for us to go out into the community and talk to people, ask them what their immediate needs – our goal is to involve communities from the very beginning of our research so that we co-develop meaningful solutions that will improve the quality of their everyday lives,” Aslan said. “Our group at Georgia Southern consists of established researchers from multiple disciplines such as environmental education, public health, social and behavioral sciences, environmental and computational engineering, coastal ecology, and we are growing everyday”. Carl L. Reiber, Ph.D., Georgia Southern’s provost and vice president for academic affairs, said the center will pull together faculty from across the University, many of whom have already established themselves as water experts within their own discipline. He expects the center to take a very visible role for the University and is renovating space in Savannah near the Armstrong campus to house the center and its labs. “The Institute for Water and Health will bring to southeast Georgia an awareness of the importance of water quality, water management and how tightly these areas are aligned with our health,” Reiber said. “The public impact of this institute is immeasurable and will ultimately increase the quality of life in our community.” If you're a journalist looking to know more about this topic or are looking to cover - then let us help. Asli Aslan, Ph.D., is a water microbiologist, and her research program bridges ecosystem and human health. She has ongoing funded projects on microbial source tracking, health risk assessment of water resources, and the ecology of pathogens in the aquatic environment. She is available to speak with reporters – simply click her icon now to arrange an interview today.
Six popular beliefs about colds: experts explain the facts
As we return to pre-lockdown levels of social mixing, colds are starting to become all too common. A TikTok video has gone viral involving putting garlic up your nose as a cold cure, just one in a long line of claimed treatments or cures. We asked two experts to examine some commonly held beliefs around colds. 1. Can you get a cold by getting cold? Colds become more common in winter. Like other upper respiratory tract infections (in the nose, throat and windpipe) they are normally caused by a virus. There might be a little truth in the idea that getting cold can give you a cold, because as the temperature changes this can alter the lining of our throat and windpipe, which can possibly make it easier for viruses to infect cells. However, the main reason we get more colds in winter is spending more time inside, closer to other people – the perfect environment to transmit viruses. 2. Does sticking garlic up your nose help? The TikTok trend involves putting cloves of garlic up your nose because it claims to act as a decongestant. Sticking something up your nose blocks the flow of mucus, so when it is removed, the flow starts and the mucus drips or even runs out of your nose. Mucus not only helps trap and remove pathogens including viruses, but also contains antibodies and can reduce how infectious and spreadable viruses are. So this is not a good idea. Garlic contains a range of compounds which might irritate the nose, and remember sticking anything up your nose isn’t a great idea. It could damage the lining and lead to bleeding or even get stuck. So it doesn’t really help and could be harmful. 3. Can herbal remedies prevent colds? Various herbal remedies claim to either prevent or speed up recovery from a cold. People often mention echinacea, a family of plants that grow in North America. Some trials have suggested a small preventative effect, but the evidence does not show statistically significant reductions in illness levels. Turmeric is also touted as a preventative medicine, but there is no robust evidence for its effectiveness either. 4. Can vitamin C help? Nobel prize-winning scientist Linus Pauling suggested that vitamin C in high doses could be an effective treatment for many viral infections. But a Cochrane review, a very robust system in which researchers assess evidence, found that vitamin C did not prevent colds, but may reduce their duration, in some people. As vitamin C supplements of around 200mg per day are considered low risk, some suggest this is a reasonable strategy to shorten the effects of a cold. 5. Does vitamin D prevent colds? Vitamin D has moved from being the sunshine vitamin associated with healthy bones, to being linked to reducing the risks around everything from heart disease and diabetes to viruses. This has included a lot of interest in vitamin D as a way of helping us fight off flu and more recently COVID-19. Laboratory experiments show that vitamin D is important in supporting immunity and this is critical in fighting off viruses. The problem may be that some people have inadequate vitamin D levels. Sunshine allows us to make our own vitamin D - but that happens less in winter. So it is likely that taking vitamin D supplements as advised by the UK government over winter is sensible so that you get enough, and this may help prevent you from getting a cold. 6. What about chicken soup? Chicken soup has been used through the ages to treat colds, and like honey it might have some benefits in managing symptoms. But it is unlikely to make a big impact on driving out the infection. The water in the soup will help with hydration, which is a often a problem when we have a cold. Like most hot drinks it can help to relieve painful sinuses. There are studies looking at the effect on our immune system cells, but the evidence from these is far from conclusive. Sadly, there are no miracle cures for the common cold. Some suggestions may be helpful, and are generally not harmful, such as getting enough vitamin C and D. But others are definitely not worth trying and could be risky, such as putting garlic up your nose. The best thing to do is get plenty of rest and drink plenty of fluids to stay hydrated.
MEDIA RELEASE: Is your vehicle ready for winter? What you need to do to prepare for the season ahead
Temperatures are getting colder, Ontarians are bundling up, and CAA South Central Ontario (CAA SCO) is recommending that now is the right time to get your vehicle winter ready. “Preparing for unpredictable driving conditions will help ease the frustration and anxiety that comes with colder weather,” says Kaitlynn Furse, director, corporate communications, CAA Club Group. “Before the winter season starts ensure your car is in tip top shape.” If you’re uncertain of when or how to get ready for winter driving, the top three things you can do right now are: packing an emergency roadside kit, installing your winter tires, and checking your car battery. CAA recommends packing a fully stocked emergency roadside kit so in case something does happen while on the road, you have everything to stay safe until help arrives. The kit should include a flashlight and extra batteries, warning devices (e.g., flares, reflective vests/strips), a first aid kit, blankets, jumper cables, non-perishable food and water plus a phone charger. Be sure to also keep an ice scraper, small shovel and snow brush handy in your car at all times. With the temperature consistently hovering around 7° Celsius, it’s important to install four matching winter tires to fully optimize your vehicle’s handling, stability and braking. “Compared to all-season tires, winter tires stay flexible in cold temperatures giving you better traction, whether or not there’s snow on the ground,” says Furse. “This may reduce your stopping distance by a few feet which can be the reason for preventing a collision.” While installing your winter tires, CAA recommends also asking your mechanic to check your car battery. “Even a fully charged battery can lose power when the temperature dips below 0° Celsius,” says Furse. “It’s important to have your car battery tested in the fall to ensure it’s ready for the winter.” Are you unsure if your car battery will make it through the winter months? Watch for the following warning signs that a battery may need to be replaced: Your vehicle cranks slowly when trying to start. It takes 175 to 250 amps of battery power to get a car going. If your car is slow to start, you might be dealing with an insufficient charge. Your headlights dim while idling. When idle, a car may draw more power than the alternator alone can produce, so your battery kicks in. If your headlights dim when you are idling but brighten when you rev the engine, it could mean a drained battery. Your digital systems power down quickly. Electronics like the radio, GPS, dash cams and other accessories, especially in modern cars, use battery power when the engine is off. If they stop functioning properly, it could suggest a weak battery. You hear a grinding, clicking or buzzing noise when you turn on the ignition. It’s important to be able to distinguish the reason your vehicle may be making noises, usually these sounds mean your battery has lost its charge but if you’re still unsure, get your vehicle checked by a professional. Your vehicle has stalled. The stored energy in your car battery is essential for starting the engine, without its juice, you won’t be going far. If your battery is giving you problems or you are unsure if it’s time to replace it, you can call CAA’s Mobile Battery Service at *222 to have a trained CAA SCO Battery Service Representative come test your battery and provide a helping hand.
Infrastructure and extreme weather expert on recent weather events
Hiba Baroud, assistant professor of civil and environmental engineering, is available for commentary on recent extreme weather events, including hurricanes, tropical storms and flooding. Baroud is an expert on infrastructure and climate change as they pertain to extreme weather events. She can speak to the potential dangers of the destruction and the cleanup decisions affected areas must make, including those that can help prepare for the future. Topics she can discuss include: How weathers and disasters are becoming more frequent and intense, therefore costing us more. Why cities must prepare before extreme weather hits, making future-based predictions and not just relying on historical data to understand potential concerns. With that, cities must also focus on restoration after an event happens, rather than prevention Additional dangers to residents' lives to be considered once the weather has passed - such as a lack of food and water, lack of power and road infrastructure issues
Aston University researchers based in the College of Health and Life Sciences have been awarded a Knowledge Transfer Partnership (KTP) project by Innovate UK, to bring its academic and scientific expertise to assist Catalent in the development of its Zydis® technology, the leading orally disintegrating tablet (ODT). The Zydis ODT fast-dissolve formulation is a unique, freeze-dried oral solid dosage form that disperses almost instantly in the mouth with no water required. It helps delivering treatments to patients and consumers who have difficulty swallowing conventional pills, or where rapid onset of action is desirable. The aim of the KTP partnership is to develop and prove an accurate predictive decision-making tool to pre-determine accurate levels of absorption enhancer for each Zydis product, potentially facilitating faster pharmaceutical development, improving efficiency, and reducing time to market. A Knowledge Transfer Partnership (KTP) is a three-way collaboration between a business, an academic partner and a KTP Associate. The UK-wide programme helps businesses to improve their competitiveness and productivity through the better use of knowledge, technology and skills. Aston University is the leading KTP provider within the Midlands. Academic lead on the project is Professor Afzal Mohammed, who is also chair in Pharmacy in the College of Health & Life Sciences (HLS) and a member of the Aston Pharmaceutics Group (APG) at Aston University. Afzal said: “This is a great opportunity for us to share and translate our academic experience in cell based models, excipient and formulation characterisation to develop an evidence based predictive tool that has the potential to expedite product development at Catalent.” Ralph Gosden, head of Zydis product development at Catalan, added: "We are excited to be working with Aston University on this project. Their expertise in drug transportation, cell biology, data analysis and model cell line design, coupled with its world-class facilities means that together, we will be able to achieve significant improvements in efficiency, and accelerate new product development.” Professor Mohammed will be supported by other colleagues from the Aston Pharmaceutics Group, including, Dr Dan Kirby, who has experience in drug delivery and improving patient acceptability of dosage forms gained through original research; Dr Affiong Iyire who has research expertise in the formulation of drugs for pre-gastric absorption and innovative cell models; and Dr Raj Badhan, who is a pharmacokinetics expert with vast knowledge of in silico methods. The outcomes of the project will be integrated into Aston University’s curriculum through teaching case studies, thereby developing well equipped graduates.
