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One AI-based advancement at a time, UF leaders are transforming the sports industry
As emerging technologies like AI reshape sport industries and professional demands evolve, it is essential for students to graduate with the expertise to thrive in their future careers. To ensure that these students are set up for success, the UF College of Health & Human Performance has launched a new sports analytics program. Led by Scott Nestler, Ph.D., CAP, PStat, a professor of practice in the Department of Sport Management and a national analytics and data science expert, the program ties back to the UF & Sport Collaborative – a five-part project intended to elevate UF’s presence on the global stage in sports performance, healthcare and communication. “Tools and insights that previously were only available to professional sports teams are now coming to the college level, and it makes sense for universities to begin using these data, technologies and new analytic methods,” Nestler said. The sports analytics program fosters collaboration between academic units, such as the Warrington College of Business and the University Athletic Association, helping bridge the gap between sport research and innovation and empowering students to address real-world challenges through data and AI. For example, the program offers opportunities to leverage technology and analytics for strategic decision making in player acquisition, team formation and in-game decisions. Beyond performance metrics, the program also explores marketing strategies and revenue analytics, providing a well-rounded understanding of the field. “When you have enough data and a large enough sample of individuals, AI can help make predictions that otherwise would take prohibitively longer for a human to accomplish with traditional methods,” said Garrett Beatty, Ph.D., the assistant dean for innovation and entrepreneurship and an instructional associate professor in the College of Health & Human Performance’s Department of Applied Physiology and Kinesiology. “Because those data volumes are getting so large, AI models, machine learning, deep learning and other strategies can be leveraged to make sense and glean insights from sport and human performance data in ways that have never been done before.” The program seeks to offer several educational opportunities, such as individual courses, certificate programs and potentially a full degree program. In the long term, Nestler envisions the program evolving into a center or institute, beginning with establishing a research lab in the spring. Additionally, the program will leverage the university’s supercomputer, HiPerGator, to analyze larger data sets and use newer predictive modeling machine learning algorithms. “As faculty and staff move from working with box score and play-by-play data to using tracking data, which contains coordinates of all players and the ball on the field or court tens of times per second, the size of data files in sports analytics has grown tremendously,” Nestler said. “HiPerGator, with its large storage capacity and multiple central processing units/graphic processing units, is ideal for using in sports analytics work in 2025.” Nestler also aims to increase student involvement by enhancing UF’s Sport Analytics Club and hiring research assistants to work on projects for the University Athletic Association. “We need to take a broader view of what AI is and realize that it incorporates a lot of what we’ve been calling data science and analytics in the form of machine learning models, which came more out of statistics and computer science. Those are types of AI and those that I think will largely continue to be used in the coming years within the sports space,” Nestler said. “Also, we’re continuing to see growth in the number of people interested in working in this space, and I don’t foresee that changing. Fortunately, we are also seeing the number of opportunities available to those with the appropriate skills increase as well.”
The University of Florida’s ‘AI Queen’ is using AI technology to help prevent dementia
To help the 50 million people globally who live with dementia, the National Institute on Aging is finding researchers to develop tech-based breakthroughs that target the disease — researchers like the University of Florida’s “AI Queen.” It’s a fitting nickname for Aprinda Indahlastari Queen, Ph.D., who is applying artificial intelligence technology to study transcranial direct current stimulation, or tDCS — a technique that involves placing electrodes on the scalp to deliver a weak electrical current to the brain — as a possible way to prevent dementia. The assistant professor in the UF College of Public Health and Health Professions’ Department of Clinical and Health Psychology is using UF’s supercomputer, HiPerGator, to perform neuroimaging and machine learning analyses to study how anatomical differences may affect tDCS outcomes. “Investigating working memory in patients with mild cognitive impairment offers an opportunity to understand how cognitive processes are disrupted in the early stages of Alzheimer’s disease,” said Queen, whose study — funded by a National Institute on Aging research career development grant — integrates neuroimaging with information on brain structure that is unique to older adults and those with mild cognitive impairment. Refining the treatment with AI Using neuroimaging, Queen captures real-time changes during tDCS to the parts of the brain associated with working memory, which is the type of memory that allows humans to temporarily keep track of small amounts of information. Think of this as a mental “scratchpad.” Her study includes older adults with mild cognitive impairment as well as individuals who are cognitively healthy. In tDCS, a safe, weak electrical current passes through electrodes placed on a person’s head. The stimulation is being used in research and clinical settings for a variety of conditions and has shown partial success as a nonpharmaceutical intervention that can improve cognitive and mental health in older adults. But tDCS results can vary across individuals, and the suspected cause is both simple and complex: Everyone’s head is different. “One potential reason tDCS may not work for some individuals is the variation in head tissue anatomy, including differences in brain structure,” Queen said. “Since electrical stimulation must travel through multiple layers of tissue to reach the brain, and every individual’s anatomy is unique, these differences likely affect outcomes.” To address this further, Queen is using AI. “Artificial intelligence will play a major role in the modeling pipeline, including constructing individualized head models, conducting predictive analyses to identify which participants will respond to the stimulation, and disentangling multiple individual factors that may contribute to these outcomes,” Queen said. An estimated 10 to 20% of adults over age 65 have memory or thinking problems characterized as mild cognitive impairment. Their symptoms are not as severe as Alzheimer’s disease and other dementias, but they may be at increased risk for developing dementia. “The fact that not all individuals with mild cognitive impairment progress to Alzheimer’s disease emphasizes the need to identify effective interventions that can slow the progression to dementia,” Queen said. “This project presents an opportunity to differentiate between multiple types of mild cognitive impairment and investigate how tDCS affects the brain across these subtypes.” An AI visionary Queen, who joined the UF faculty under the university’s AI hiring initiative, is an instructor in the College of Public Health and Health Professions’ undergraduate certificate program in AI and public health and health care, and the co-chair of the college’s AI Workgroup. She is also the assistant director for computing and informatics at the UF Center for Cognitive Aging and Memory Clinical Translational Research and a member of UF’s McKnight Brain Institute. Queen received her Ph.D. training in engineering with a focus on building and running computational models to investigate medical devices. She experienced a career “a-ha” moment as a postdoc, when she was a co-investigator on a large clinical trial that paired brain stimulation with cognitive training to enhance cognition in older adults. “This experience was transformative for me. I had the chance to interact directly with participants, which was both fulfilling and eye-opening. These interactions allowed me to see the immediate, real-world implications of my work and sparked a passion for pursuing aging research,” Queen said. “I realized that, through this type of research, I could have a more direct impact on addressing age-related challenges, which prompted a shift in my career plans.” The new grant will help Queen further improve her understanding of the neurobiology and progression of Alzheimer’s disease and other dementias. “These experiences will ultimately prepare me to become a well-rounded aging investigator, capable of making meaningful contributions to the field of aging research,” Queen said. She also credits her mentors and collaborators — Ronald Cohen, Ph.D.; Adam Woods, Ph.D.; Steven DeKosky, M.D.; Ruogu Fang, Ph.D.; Joseph Gullett, Ph.D.; and Glenn Smith, Ph.D. — with supporting her as an early career scientist. “It really takes a village to get here!” Queen said.
Masoud Davari, an associate professor in Electrical and Computer Engineering at Georgia Southern University, has been awarded the 2024 IEEE Region 3 Outstanding Engineer Award, making him the first faculty member in the university’s 55-year history to receive this honor. Davari was recognized for his contributions to reinforcement-learning optimal controls for power-electronic converters, his work on integrating power-electronic systems with cyber-attack considerations in modern power grids, and for his leadership in hardware-in-the-loop testing and standards development, including service on the IEEE P2004 standards working group. In addition to the award, Davari was inducted into the IEEE-Eta Kappa Nu (HKN) honor society. His research program at Georgia Southern has earned significant support, including more than $1.17 million in National Science Foundation funding, a 2024 Gulfstream Aerospace Research Fellowship, inclusion in the Stanford/Elsevier Top 2% Scientists list, and selection as a finalist for the 2024 Curtis W. McGraw Research Award. You can find out more about Davari's research by visiting his Georgia Southern Scholars profile below: To arrange an interview or to learn more about this award - Looking to know more about Georgia — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
How UF researchers are helping Floridians to build resilience
When Hurricane Idalia hit the Big Bend region of Florida in 2023, Jeff Carney and his team were watching. A coalition of architects, planners, and landscape architects led by Carney worked closely with the tiny Gulf island of Cedar Key, which is particularly vulnerable to hurricanes, to prepare for this moment. The researchers had modeled for city officials how a major storm would flood the city’s core services. “Idalia caused flooding exactly where the maps said it would, including city hall, the historic downtown, older homes, and many streets,” Carney said. After the storm, Cedar Key moved city hall to higher ground, as outlined in the plan. And just in time. Barely a year later, Cedar Key was hit even harder by Hurricane Helene. Between the storms, Carney’s group had worked with the city to refine their storm preparation. The new plan focused more on resilience-boosting projects, like improving drainage around the city. Cedar Key finalized their plans just weeks before Helene. “A lot of the projects we put forward in this plan are in the process of seeking additional funding after Helene,” Carney said. A professor of architecture at the University of Florida, Carney directs the Florida Institute for Built Environment Resilience, or FIBER. A research institute in UF’s College of Design, Construction and Planning, FIBER engages with communities to understand how the designs of buildings and cities expose Floridians to risks — not just storms, but also excessive heat, poor air quality, even a lack of health care. FIBER faculty then work with cities to mitigate these hazards. By preparing for emergencies, upgrading buildings, and providing targeted services, communities across Florida are bolstering the resilience of their residents, all with expert help from UF researchers. Preparing to weather big storms That kind of resilience is especially important for some of Florida’s most vulnerable residents. Older and poorer Floridians face higher-than-average risks from natural disasters and other environmental hazards. That vulnerability was apparent in Cedar Key as it weathered the last two hurricane seasons. Centered around aquaculture and tourism, Cedar Key seems in many ways to be thriving. Yet, with the feel of a small fishing village, roughly 13% of its nearly 1,000 full-time residents are considered to be financially disadvantaged, according to U.S. Census data. Poorer residents may also have a harder time walking away from coastal communities devastated by storms. With savings invested into damaged homes and jobs tied to the local area, less-wealthy residents often have no choice but to stay and rebuild. Carney’s team helps people see the opportunities for rebuilding with a clearer vision of a future where rising sea levels are a reality. “You capture people’s attention and excitement when you can offer them options that are not doomsday,” said Carney, who has been working in Pine Island and Matlacha in Southwest Florida’s Lee County to help residents affected by recent storms prepare for the future. “There’s a lot of opportunity for rebuilding as long as you don’t try to have it be business as usual. We help people see how redevelopment can provide a community asset for the future,” he added. “We try to paint the picture of all the possible scenarios so people can find their own comfort level. It puts them in the driver’s seat.” Aging with fewer choices While that kind of agency is empowering, it can be harder to come by as people retire and find themselves facing tough decisions on fixed incomes. That’s a common experience in Florida, which has a larger proportion of seniors than any other state, due in part to its popularity as a retirement destination. More than 10% of Americans over the age of 65 live below the federal poverty line. This population often finds themselves moving to less safe places as they age. “Older people with more social vulnerability — such as low income or poor health — have a tendency to move to worse places,” said Yan Wang, Ph.D., a professor of urban and regional planning in the UF College of Design, Construction and Planning. “They are more likely to move to places with less economic stability, with less access to health care, and with more exposure to extreme weather.” Wang and postdoctoral researcher Shangde Gao, Ph.D., recently published a study that uncovered the risks low-income seniors face when moving. Compared to their peers with higher incomes, poorer seniors were more likely to end up in neighborhoods lacking access to health care facilities. To address these kinds of disparities, UF Health has launched mobile health units that can reach people who have trouble traveling to health centers, including low-income seniors. The Mobile Outreach Clinic provides primary care and referrals for specialists. And the newly launched cancer screening vehicle, which serves all of North Central Florida, can help catch the disease in the early stages when it is easiest to treat. It’s not just finding health care that’s a struggle. Older adults from minority racial groups were also more likely to increase their exposure to poor air quality and to natural disasters like flooding and hurricanes when they moved, Wang and Gao discovered. “If we understand the trend and causes of these income disparities better, we could better prepare some places with more health care resources or better hurricane preparation for these older populations,” Wang said. Building safer, healthier homes That preparation is happening right now in Jacksonville, not just for big storms but for the everyday nuisances and hazards — even the ones people are exposed to in their own homes — that threaten people’s lives and health. The Jacksonville Restore and Repair for Resiliency research initiative was founded to address these kinds of risks while improving energy efficiency. The R3 initiative, as it’s known, is a home remodeling program organized by a slew of community partners and supported by FIBER research on the impact of housing quality on health. The project aims to keep longtime residents of the Historic Eastside in their homes while addressing the home hazards that put people at risk for medical complications like asthma attacks and emergency room visits. “The designs of buildings impact human health and well-being,” said Lisa Platt, Ph.D., the lead researcher with the Jacksonville program and an assistant professor of interior design with FIBER. “Our research is helping the team prioritize the home improvements that will benefit residents’ health the most.” Jacksonville’s Eastside faces a lot of challenges. The population is older than the city as a whole. Roughly three-quarters of residents are over the age of 60, and the poverty rate is over 40%. Yet more than a third of residents own their own homes. Often passed down from previous generations, some of the houses are now over a century old and struggle to keep the intense Florida heat and humidity out. Platt’s research has modeled how things like high heat days — only growing more common in a warming world —are associated with increased emergency room use and poor perceived physical and mental health. That science helps guide the community partners to prioritize providing air conditioning and better insulation to protect Historic Eastside residents. To date, the Jacksonville program is targeting up to 70 homes for renovation. Builders have fixed holes in roofs, replaced drafty windows, and hooked up air conditioning for the first time, keeping the heat and humidity at bay and protecting residents’ health. Now the R3 initiative is applying for federal grants to expand the program. “I think the best way to approach this kind of community action research is with humility and outreach. Community members have amazing expertise. I always say, ‘I can build models to analyze the problem, but you are the ones that are the experts,’” Platt said. “That’s where UF can be most useful, is coming in from a perspective of service.”
“See a gap, fill a gap.” That’s how Jeffrey Klibert, Ph.D., associate director of clinical training in Georgia Southern University’s Doctor of Psychology (PsyD), described the inspiration behind a project designed to extend behavioral health services in rural areas. Filling gaps is something Klibert said has always been a challenge in behavioral health care. This challenge became steeper in the aftermath of the COVID-19 pandemic. “When COVID hit, we saw some really alarming rates of people seeking services, and there just weren’t enough providers to meet that need,” Klibert said. “We saw waitlists that were six months, eight months, sometimes a year long.” Waitlists of this length are a common occurrence in Georgia’s rural areas, where resources are scarce and reported health outcomes are among the worst in the state. Klibert, along with colleagues Lindsey Stone, Ph.D., and Thresha Yancey, Ph.D., and students, is working to improve the situation across 14 rural counties in Georgia, thanks to the renewal of a research and training grant from the Health Resources and Services Administration. Stone and Yancey will supervise the trainees, while Klibert will oversee the entire program. The grant enables quantitative and qualitative research to increase access to behavioral health care in rural areas, while also providing Georgia Southern’s fourth-year PsyD students with hands-on training through local care providers. The ultimate goal is to develop more efficient and effective models for interprofessional, team-based care in areas of the state where it is most needed. “Everybody sees the need. We just need the glue to link everybody together,” Klibert said. “That’s what the program is trying to be. It’s trying to build those bridges to create a more comprehensive system of care.” Students will provide a range of services in collaboration with local care providers, including psychological assessments and therapy for individuals and families. Alex Cudd, a fourth-year PsyD student who joined the program in August, calls the experience “invaluable” and hopes to join the 94% of program alumni who currently provide care in rural settings. “In just a few months, I’ve learned so much about providing well-rounded care,” Cudd said. “I know I’ll carry this training into my career.” CarePartners of Georgia (CPGA), a resiliency- and recovery-based behavioral health agency serving Bulloch, Candler and Emanuel counties, is among the local providers partnering with Georgia Southern. “All the interns we’ve had from Georgia Southern understand the concept of recovery, are trauma-informed and very effective at delivering services,” said CPGA CEO David Crooke. “It’s been mutually beneficial. We are helping them further their education, and they quickly become important members of our team due to the breadth and depth of their knowledge.” Klibert notes that the grant’s initial four-year term brought significant improvements in local healthcare networks and enhanced communication between providers, something he sees as an investment in lasting success. “We’re doing some exciting stuff, but at the end of the day, we are very aware of making sure what we’re doing sticks and that we have the resources to continue care after the grant ends,” Klibert said. Looking to know more about Georgia Southern University's Doctor of Psychology Program or arrange an interview with Jeffrey Klibert — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
Georgia Southern faculty featured on prestigious top 2% of scientists list
Twelve outstanding active faculty members from Georgia Southern University were featured on Stanford and Elsevier’s 2025 list of the top 2% of scientists in the world. This annual list features scientists whose work has had the highest citation count and citation impact in their fields within a given year. This year’s Georgia Southern honorees represent a diverse range of disciplines, from physics and chemistry to epidemiology and business. Ten of the 12 faculty members were also featured on last year’s list. Vice President for Research and Economic Development David Weindorf, Ph.D, P.G., is among them and takes pride in seeing so many familiar names, and a couple of new ones, included. “Seeing names from so many different disciplines, both old and new, speaks volumes about our growth and consistency,” said Weindorf. “I’m so thankful for these faculty who relentlessly pursue excellence and truly embody growing ourselves to grow others in research.” Check out who made the list from Georgia Southern by clicking on the attached media release below: Looking to know more about Georgia Southern University and it's nationally recognized faculty — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
RPI Hosts Launch Event for New Center for Smart Convergent Manufacturing Systems
Rensselaer Polytechnic Institute (RPI) officially cut the ribbon on its new Center for Smart Convergent Manufacturing Systems (CSCMS) during an all-day launch event on October 23, 2025. A New York State Center for Advanced Technology, CSCMS will redefine the very nature of manufacturing by combining robotics, artificial intelligence, advanced processing, and human ingenuity to create systems that think, adapt, and evolve alongside human operators. “Today we mark the official opening of a center with a bold vision: a future where manufacturing systems are not simply automated, but truly intelligent,” said RPI President Martin A. Schmidt ’81 during the ribbon cutting. CSCMS will bring a wealth of opportunities not only to RPI, but across New York State. The new center will serve as a catalyst for economic growth, empowering innovators, driving new technologies, and strengthening the competitiveness of manufacturers. At RPI, students will gain hands-on experience in labs, real-world projects, and entrepreneurial pathways. Faculty and industry partners will gain the resources to translate cutting-edge research into commercial solutions. “Through simulation, prototyping, and translational research, our faculty and students will work side by side with industry and government to accelerate the development and deployment of smart manufacturing solutions,” said President Schmidt. “This is the RPI model at its very best: turning ideas into impact.” The launch event for CSCMS took place on RPI’s campus and featured keynote remarks, a ribbon cutting, industry panel, poster sessions, lab tours, and demonstrations of robotic manufacturing, human-machine collaboration, smart manufacturing testbeds, intelligent production systems, and data visualization spaces. Industry panel speakers included executives from FuzeHub, Ross Precision Manufacturing, GE Aerospace Research, and The Boeing Company. Interactive student poster sessions covered topics such as robotics, AI, advanced manufacturing, and New York’s future at the convergence of these topics. “The launch of CSCMS comes at a pivotal time for manufacturing,” said Johnson Samuel, Ph.D., director of CSCMS. “Across industries, we are seeing the convergence of AI, robotics, and data-driven design transforming how products are made. RPI’s long-standing strengths in engineering, computing, and innovation make it the perfect home for this next-generation center.” “The energy and collaboration we saw during this event are a reflection of the momentum behind the entire CSCMS initiative,” said Sandipan Mishra, Ph.D., associate director of CSCMS. “This launch is the start of a sustained effort to shape the future of intelligent manufacturing in New York and beyond.” "It's exciting that as students, we get to work with these cutting-edge technologies up close and be a part of something that’s pushing manufacturing forward,” said RPI graduate student Ammar Barbee ‘25, who recently completed his bachelor’s degree in mechanical engineering at RPI. “Perusing this kind of research and having access to such advanced equipment enables unique experiences that will really help accelerate our careers.” With the launch of CSCMS, RPI continues to advance its legacy of innovation and partnership, bringing together academia, industry, and government to drive progress in intelligent manufacturing and strengthen New York’s position as a hub for technological excellence.
American Nuclear Society names Lane Carasik, Ph.D., as one of its “40 Under 40”
Recognized as an emerging leader in the nuclear science and engineering field, Lane Carasik, Ph.D., assistant professor in the Department of Mechanical and Nuclear Engineering, was recently acknowledged by the American Nuclear Society as one of its top “40 Under 40.” “It is a huge honor to receive this acknowledgement from my professional community,” said Carasik. “I feel it is a reflection of the amazing nuclear engineering activities I’ve gotten the opportunity to pursue before and during my time at the VCU College of Engineering.” The list, featured in the most recent issue of Nuclear News magazine, celebrates young professionals who are driving innovation and shaping the future of nuclear science and technology. Created to spotlight a new generation of nuclear professionals, the “40 Under 40” program highlights those who are advancing technical fields, from advanced reactor deployment to AI applications and national security, while actively engaging the public, mentoring peers and advocating for nuclear’s role to achieve energy independence and security. “Dr. Carasik’s research efforts, together with his support for students and their own research goals, exemplifies the best qualities of the VCU College of Engineering,” said Arvind Agarwal, Ph.D., chair of the Department of Mechanical and Nuclear Engineering, “integrating research and teaching at the core of everything he does, from classroom and lab work to community outreach.” Carasik was selected for the “40 Under 40” from hundreds of candidates across the United States. Mentoring his first three Ph.D. graduates, Arturo Cabral, Connor Donlan and James Vulcanoff, is one of Carasik’s proudest achievements. He was also honored by the American Society of Mechanical Engineers (ASME) as a rising star in mechanical engineering in 2024 This builds off Carasik receiving the highly competitive and prestigious Department of Energy (DOE) Early Career Research Award ($875k split over five years) in 2023 to support his work on molten salt based fusion energy systems similar to Commonwealth Fusion Systems’ ARC technology. Carasik’s Fluids in Advanced Systems and Technology (FAST) research group, is a computational and experimental thermal hydraulics group focused on enabling the development of advanced energy systems and critical isotope production methods. Legendary physicist Enrico Fermi was an early inspiration to Carasik during his undergraduate studies. Fermi’s expertise mirrored Carasik’s interests, and the physicist’s impact on the field of nuclear engineering was motivating. As an established nuclear engineering faculty member, Carasik seeks to make a lasting impact on the field and the people in it. His ’s long-term goal is earning membership in the National Academies of Sciences, Engineering and Medicine.
Heart valve developed at UC Irvine shines in early-stage preclinical testing
UC Irvine researchers designed and developed a minimally invasive replacement pulmonary heart valve. Created for pediatric patients, the device can be expanded as children grow, eliminating the need for multiple surgeries. The team successfully conducted laboratory and early-stage animal feasibility testing of the implant, crucial steps toward approval for human use. Irvine, Calif., June 23, 2025 — Researchers at the University of California, Irvine have successfully performed preclinical laboratory testing of a replacement heart valve intended for toddlers and young children with congenital cardiac defects, a key step toward obtaining approval for human use. The results of their study were published recently in the Journal of the American Heart Association. The management of patients with congenital heart disease who require surgical pulmonary valve replacement typically occurs between the ages of 2 and 10. To be eligible for a minimally invasive transcatheter pulmonary valve procedure, patients currently must weigh at least 45 pounds. For children to receive minimally invasive treatment, they must be large enough so that their veins can accommodate the size of a crimped replacement valve. The Iris Valve designed and developed by the UC Irvine team can be implanted in children weighing as little as 17 to 22 pounds and gradually expanded to an adult diameter as they grow. Research and development of the Iris Valve has been supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development; the National Heart, Lung, and Blood Institute; and the National Science Foundation. This funding has enabled benchtop fracture testing, which demonstrated the valve’s ability to be crimped down to a 3-millimeter diameter for transcatheter delivery and subsequently enlarged to 20 millimeters without damage, as well as six-month animal studies that confirmed successful device integration within the pulmonary valve annulus, showing valve integrity and a favorable tissue response. “We are pleased to see the Iris Valve performing as we expected in laboratory bench tests and as implants in Yucatan mini pigs, a crucial measure of the device’s feasibility,” said lead author Arash Kheradvar, UC Irvine professor of biomedical engineering. “This work represents the result of longstanding collaboration between our team at UC Irvine and Dr. Michael Recto at Children’s Hospital of Orange County built over several years of joint research and development.” Congenital heart defects affect about 1 percent of children born in the United States and Europe, with over 1 million cases in the U.S. alone. These conditions often necessitate surgical interventions early in life, with additional procedures required to address a leaky pulmonary valve and prevent right ventricular failure as children grow. The Iris Valve can be implanted via a minimally invasive catheter through the patient’s femoral vein. The Kheradvar group employed origami folding techniques to compress the device into a 12-French transcatheter system, reducing its diameter to no more than 3 millimeters. Over time, the valve can be balloon-expanded up to its full 20-millimeter diameter. This implantation method, along with the ability to begin treatment earlier in very young patients, helps mitigate the risk of complications from delayed care and reduces the need for multiple surgeries in this vulnerable population. “Once the Iris Valve comes to fruition, it will save hundreds of children at least one operation – if not two – throughout the course of their lives,” said Recto, an interventional pediatric cardiologist at CHOC who’s also a clinical professor of pediatrics at UC Irvine. “It will save them from having to undergo surgical pulmonary valve placement, as the Iris Valve is delivered via a small catheter in the vein and can be serially dilated to an adult diameter and also facilitate the future placement of larger transcatheter pulmonary valves – with sizes greater than 20 millimeters, like the Melody, Harmony and Sapien devices – if needed.” Kheradvar said that the next phase of preclinical testing of the Iris Valve is funded by the Brett Boyer Foundation, which is committed to supporting research into treatments for congenital heart disease. “We are actively engaged with the U.S. Food and Drug Administration to define and carry out the required experiments and documentation for first-in-human authorization of the Iris Valve,” Kheradvar said. “Our team is urgently advancing the Iris Valve through preclinical studies to enable its clearance for first-in-human use. This is a critical step toward providing toddlers – who currently have no viable minimally invasive treatment until they reach the 45-pound threshold – with a much-needed option.” First co-author Nnaoma Agwu, a biomedical engineering Ph.D. candidate at UC Irvine, said: “The development of the Iris Valve required a strong and knowledgeable team that understood the clinical and mechanical design requirements. This accomplishment would not have been possible without the collaboration of talented clinicians, veterinarians and engineers. With this milestone reached, we are rigorously advancing the Iris Valve’s development, setting our sights on human clinical trials.” Joining Kheradvar, Recto and Agwu as co-authors of the article in Journal of the American Heart Association were Daryl Chau, a recent UC Irvine master’s graduate; Gregory Kelley and Tanya Burney, both research specialists at UC Irvine, with Burney also affiliated with the Beckman Laser Institute; Ekaterina Perminov, a clinical veterinarian with UC Irvine’s University Laboratory Animal Resources; and Christopher Alcantara, a radiology technician at CHOC. About UC Irvine’s Brilliant Future campaign: Publicly launched on Oct. 4, 2019, the Brilliant Future campaign aims to raise awareness and support for the university. By engaging 75,000 alumni and garnering $2 billion in philanthropic investment, UC Irvine seeks to reach new heights of excellence in student success, health and wellness, research and more. The Samueli School of Engineering plays a vital role in the success of the campaign. Learn more by visiting https://brilliantfuture.UC Irvine.edu/the-henry-samueli-school-of-engineering About the University of California, Irvine: Founded in 1965, UC Irvine is a member of the prestigious Association of American Universities and is ranked among the nation’s top 10 public universities by U.S. News & World Report. The campus has produced five Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UC Irvine has more than 36,000 students and offers 224 degree programs. It’s located in one of the world’s safest and most economically vibrant communities and is Orange County’s second-largest employer, contributing $7 billion annually to the local economy and $8 billion statewide. For more on UC Irvine, visit www.uci.edu. Media access: Radio programs/stations may, for a fee, use an on-campus studio with a Comrex IP audio codec to interview UC Irvine faculty and experts, subject to availability and university approval. For more UC Irvine news, visit news.uci.edu. Additional resources for journalists may be found at https://news.uci.edu/media-resources.
UF builds community resilience in Jacksonville’s Historic Eastside neighborhood
As the University of Florida continues to expand its presence in Jacksonville, Gators are undertaking sustainability projects to improve the city’s neighborhoods. Faculty and students in the College of Design, Construction and Planning’s Florida Institute for Built Environment Resilience (FIBER) have spent the past four years focusing on the role of housing design in community health resilience in Jacksonville’s Historic Eastside neighborhood, interviewing resident stakeholders and collaborating with citywide organizations that are helping to restore older homes. Findings from the UF research will be instrumental in informing future community planning and housing design decisions, potentially leading to more health-centered, sustainable neighborhoods. “Our research in Jacksonville focuses on how we can inform the development of community infrastructure that holistically supports human well-being across mental, emotional, and physical dimensions,” said Lisa Sundahl Platt, Ph.D., a FIBER research faculty member and an assistant professor of interior design at UF, who added that this holistic, health-centered approach is known as salutogenic design. “We are also actively collaborating with community organizations in Jacksonville and researchers from UF to explore improved strategies for designing and constructing community infrastructure that effectively responds to potential hazards.” A community-wide collaboration UF has conducted a pilot study over the past year on the Jacksonville-based Restore, Repair, and Resilience (R3) initiative that is underway in Historic Eastside – surveying residents about how the design quality of their housing and surrounding environments affects their overall well-being. This interdisciplinary project has brought together FIBER and members of the R3 Group – a coalition of organizations that includes the JEA utility company, LIFT JAX (committed to eradicating generational poverty), the Historic Eastside Community Development Corporation, the United Way of Northeast Florida, and Local Initiatives Support Corporation Jacksonville. FIBER-led research has received ongoing support from the Florida Resilient Cities grant, which is funded by the Jessie Ball duPont Fund. The scope of the R3 project is being scaled up through a U.S. Department of Energy grant awarded through JEA, which will allow for an expansion of home revitalization efforts in Eastside Jacksonville. FIBER’s ongoing housing and health community action research on these efforts will be supported through a grant from the LS3P Foundation. “Many residences we evaluated need help with improvements to housing energy efficiency, building ventilation, building shell structural integrity, and materiality,” Platt said. “For example, underperforming flooring material can create potential trip hazards for older adults. Deterioration in interior materials, caused by degrading components of the building envelope, can also lead to mold and mildew growth in interior environments, which can contribute to poor interior environmental quality issues and acute and chronic health conditions.” Respiratory health issues are often caused by material and ventilation design failures, which can affect people of all ages, especially vulnerable populations such as children and older adults. Oftentimes, interior designers see that the environmental risks that compromise human well-being are coming from both the outside and inside of the buildings. “As we continue to address priorities, our focus extends beyond energy and building efficiency to encompass comprehensive factors of built environment resilience that impact overall community health and well-being,” Platt said. “There's still significant progress to be made in the design of sustainable housing that supports community salutogenic health." Keeping residents safe and healthy UF research has continued to prove that interior resilience for living environments plays a vital role in people’s mental and physical health. “People spend roughly 90% of their time indoors, so it is important to understand the types of design conditions and materials that we’re putting into spaces and how they can affect the occupants of those living in said spaces,” said UF student Milena Rodriguez Mendez, who is one of Platt’s graduate research assistants. Students like Mendez are using qualitative and quantitative research methods to engage in collaborative community-led research that includes academics, for-profit organizations, nonprofits, citizen scientists, and neighborhood stakeholders. “I aim to center my work on social justice and equity, and I believe this initiative represents a meaningful step in that direction,” Mendez said. “Our focus is on the residents of this vibrant yet at-risk community.” FIBER researcher Jason von Meding added, “We want to know how future housing policies can address some future health concerns. We have a lot of youth in the community that are participating, which I think is important.” The FIBER housing and health team is actively pursuing additional funding to expand this research, in collaboration with UF Health Jacksonville’s Department of Community Engagement. “Our goal is to develop an open-source online platform that disseminates lessons learned and proof-of-concept findings on the impact of regenerative housing design on human and ecological health,” Platt said. “This resource will be valuable for other cities and neighborhoods facing similar challenges in housing quality, affordability, and accessibility.” Looking to know more about this project or connect with Lisa Platt? Simply click on her icon now to arrange an interview today.
