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MESOX, a spin-out from the pharmaceutics group at Aston Pharmacy School, develops drug carrier technology to improve medicine formulations The company won the Start-Up prize at the Medilink Midlands Awards 2024 The prize is awarded to a new company that shows a promising future. A spin-out company from Aston University’s pharmaceutics research group has won a medical technology and life sciences industry award. MESOX, which was founded by Aston University pharmaceutics lecturer Dr Ali Al-Khattawi, won the Medilink Midlands Start-Up Award, which is presented to a newly established company that shows a promising future. The Medilink Midlands Business Awards showcase the best collaborations between industry, academia and the NHS across the Midlands. This year’s ceremony was held at the Athena in Leicester on 9 May. The awards were established by Medilink Midlands, which provides specialist business support to boost the region’s economic output from the life sciences industry. Working alongside the Midlands Engine and other strategic alliances, it helps stimulate additional and value-added growth of the Midlands as a prosperous community for life sciences. With in-depth expertise in particle engineering for drug delivery and pharmaceutical spray drying, MESOX uses IP-protected carriers to improve the bioavailability and efficacy of pharmaceuticals, partnering with pharmaceutical and biotechnology companies to bring challenging therapeutics to market. In its citation, Medilink Midlands described MESOX as “transforming pharmaceutical formulation with its game-changing carrier technologies.” As a winner of a Medilink Midlands award, MESOX will now be entered into the UK National Awards, the ceremony of which takes place on 11 July 2024 in London. Dr Al-Khattawi said: “We are delighted to have won this prestigious award, which highlights the outstanding research and development work being done by the MESOX team and the immense potential of our company to transform the medicine formulation development landscape. Through collaboration with other pharmaceutical companies, clinicians, academic researchers, and by engaging directly with patients to understand their needs, we aim to innovate and advance drug delivery science into life-saving therapeutics. “At MESOX, our ambition is to be a global, research-based pharmaceutical company rooted in the Midlands, dedicated to developing life-saving therapeutics at speed and resource-efficiency. Our ultimate goal is to enable healthier lives for patients worldwide and ensure better global access to essential medicines.”
Aston Institute of Membrane Excellence’s Dr Matt Derry was joined by Dr Alan Goddard and France-based research partner Dr Mona Semsarilar They discussed the BIOMEM project, which received £3m from the European Innovation Council (EIC) Pathfinder programme BIOMEM will develop a bioinspired membrane to selectively extract compounds from water (like finding a favourite chocolate in a box) In the latest Aston Institute for Membrane Excellence (AIME) podcast, three researchers discuss the international BIOmimetic selective extraction MEMbranes (BIOMEM) project and how it will feed into AIME’s work. BIOMEM will develop a bioinspired membrane technology to selectively extract compounds from water, using 50-75% less energy than current state-of-the-art nanofiltration technologies. The membranes will work at low pressures and at low concentration of the target molecule. Podcast host Dr Matt Derry was joined by fellow AIME researcher Dr Alan Goddard and Dr Mona Semsarilar from the French National Centre for Scientific Research (Centre national de la recherche scientifique (CNRS)). The BIOMEM project, which involves collaborators from across Europe, is being led by Dr Torsten Bak from Danish company Aquaporin, with Dr Goddard the research lead at Aston University. Dr Goddard explained: “You might want to work on a biotechnology process where you've made a high value chemical that you want to extract from a complex mix, and at the moment you might have to concentrate your solution up, and you might have to do six or seven filtration steps. We want a filter that does it in a single step using a biological transporter. “And if you can do that in a single step in a platform technology, you'll make all these brilliant biotech processes more commercialisable, reduce your reliance on petrochemicals, and to maybe oversell what we can do, save the planet.” Dr Derry likened it to a quick way to find your favourite chocolate in a box at Christmas. Rather than scrabbling through, taking out one type at a time until you find your favourite, the process can immediately separate it out with minimal effort. Aquaporin has developed a membrane that can selectively transport only water molecules to quickly purify water, which is already in use across the world, and even out of this world, for space missions. Dr Bak and the team will bring their membrane expertise to the project. The team at CNRS, led by polymer scientist Dr Semsarilar, is working on a number of projects for BIOMEM, including developing a type of crystalline material called trianglamine, which they can modify through chemical processes to be hydrophobic or hydrophilic to make things like water channels or adsorption sites, which can be embedded in polymer network for purification processes. Other researchers at AIME, including Dr Derry and Professor Paul Topham, will work on the ‘glue’ to stick the biological elements of the membranes to the non-biological polymer matrix. BIOMEM will also benefit from the input of partners across Europe including dsm-firmenich, University of Copenhagen and Tampere University. The podcast was recorded just after the project kick-off meeting with all the project partners, which was held at Aston University in May 2024. Listen to the full podcast on the Aston Originals YouTube page.
Career advice: Expert provides tips for acing job interviews
Later this month, a whole new class of graduating seniors will hit the job market. University of Delaware career expert Jill Gugino Panté has advice for them and others seeking employment that can help boost confidence and chances for success when entering job interviews. Panté, director of the Lerner Career Services Center in UD's Lerner College of Business & Economics, provided the following tips: Hand write your answers to common interview questions. Research shows that people have a better chance of remembering information if it’s handwritten. So, rather than typing answers out on your computer, grab an “interview prep” notebook and start writing down your stories to have a better chance of remembering them when it comes time to interview. Practice saying your answers out loud. Written communication is very different from verbal communication. Once you have your answers written down, practice them out loud. This allows you to warm up your voice and get used to talking about yourself out loud. You can do this alone in a room or with a trusted friend who will give you honest feedback. Fan out notes around your screen. Now that most interviews have moved to a virtual format, take advantage of having some extra help. Put post it notes around your screen instead of in a notebook at your side so your eyes and attention stay toward the camera. Exercise beforehand. Of course, you don’t want to run a marathon right before your interview, but you can do some quick exercises to get your blood and endorphins pumping which can have a positive effect on the body and mind. I personally like to dance to an upbeat song that triggers happy memories. To set up an interview with Panté, visit her profile and click on the "contact button." This will send a message directly to her.
Aston University hosts event to foster innovation in crisis and disaster research
The two-day conference brought together academics and policy experts Its aim was to strengthen crisis and disaster research cooperation between institutions in Taiwan and Nepal with Hounslow Borough Council and Birmingham City Council The event laid the groundwork for ongoing cooperation and knowledge exchange in disaster management. Aston University has welcomed a delegation of global disaster management experts to a two-day conference aimed at fostering collaboration and innovation in crisis and disaster research. The event held at Conference Aston from 12 to 14 May 2024 brought together leading academics, policy experts and industry professionals, with a particular focus on strengthening cooperation between institutions in Taiwan and Nepal together with Hounslow Borough Council and Birmingham City Council. Since mid-2019, a concerted effort has been underway to harness innovative technologies for geoclimatic hazards monitoring in Nepal, the Philippines and Bhutan. Supported by the National Science and Technology Center for Disaster Reduction in Taiwan, this initiative has seen meaningful partnerships between British and Taiwanese stakeholders, driving advancements in real-time data capture for earthquake activity, rainfall patterns and wind dynamics crucial for effective crisis and disaster governance. Dr Komal Aryal, a lecturer in crisis and disaster management at Aston University, said: “I was wonderful to welcome such esteemed experts and colleagues to campus for this important event. “Sharing success stories and addressing implementation challenges to emerging technologies in local crisis and disaster management is vital in strengthening digital research infrastructure and networks at the grassroots level in countries like Nepal, Bhutan, the Philippines and other Himalayan regions. “The event served as a nexus for fostering partnerships among academia, policymakers, industries, emergency services and humanitarian volunteers across the UK, Nepal and Taiwan. “These collaborations are essential for driving impactful solutions and strategies in disaster management.” Professor Zoe Radnor, Pro-Vice-Chancellor and Executive Dean of the College of Business and Social Sciences at Aston University, said: “I’d like to thank everyone who attended this important event around disaster management. “It was wonderful to see the renewed commitment to enhancing crisis and disaster research cooperation which are integral to developing comprehensive and sustainable disaster response frameworks. “I am delighted to see draft plans produced for future joint collaborative activities, laying the groundwork for ongoing cooperation and knowledge exchange in disaster management.” Rev. Weilien Lin, programme secretary, Church and Society Committee, the Presbyterian Church in Taiwan, said: “This conference marks a significant step forward in our collective efforts to enhance global resilience to disasters. “By bringing together diverse expertise and fostering meaningful partnerships, we are better equipped to address the complex challenges posed by natural and man-made crises.” Professor Yie-Ru, from Chiu Tzu Chi University, Taiwan, said: “Aston University and Tzu Chi universities have entered into a Memorandum of Understanding (MoU) to collaborate more closely in addressing disaster and crisis management studies not only in Taiwan and the United Kingdom but also abroad. “This partnership marks a significant step forward in our shared commitment to enhancing global preparedness and response to emergencies, fostering cooperation and knowledge exchange across borders.” Mayor Narulal Chaudhary, general secretary of Municipal Association of Nepal elected mayor of Ghorahi Sub Metropolitan City, said: “This relationship with Aston University stands as a testament to how collaboration can foster disaster resilience and fortify crisis management efforts, especially in regions like the Himalayas in South Asia where vulnerability to natural disasters like earthquakes is significant. “As someone elected as the mayor of Ghorahi Sub Metropolitan City, a region highly susceptible to earthquakes, I believe that such collaborations are crucial in equipping communities with the knowledge and resources needed to mitigate risks and respond effectively in times of crises.”
Aston University scientist to help make crop monitoring easier and cheaper
Photonics expert Dr Sergey Sergeyev to help make crop monitoring easier and cheaper with remote sensing The technology can be placed on drones and flown over crop fields to provide real-time information about crop health Remote sensing is an essential tool to provide real-time information about crops to estimate yields. An Aston University photonics expert has received a Royal Society Industry Fellowship grant to help make crop monitoring easier and cheaper with remote sensing technology. Dr Sergey Sergeyev of Aston Institute of Photonic Technologies (AIPT) has received £174,000 to improve polarimetric LIDAR, a technology that uses light to remotely observe plants. LiDAR, an acronym for Light Detection and Ranging, involves light sent from a transmitter which is reflected from objects. Devices with this technology can be placed on drones and flown over crop fields to provide real-time information about crop health to help farmers forecast the success of their crops. Polarimetric synthetic-aperture radars (SARs) and polarimetric LiDARs are the most advanced, cost-effective sensors for crop monitoring. They are often used onboard aircraft and satellites and have been in use for three decades. However, current polarimetric LIDAR systems have low spatial resolution, a slow measurement speed and use expensive components that limit their cost effectiveness. Dr Sergeyev will be working in collaboration with Salford-based digital and AI farming company Fotenix to meet farmers' need for a cost-effective solution to check if their plants are adequately watered and disease-free. The team will aim to advance recently patented AIPT technology of the polarimetric LIDAR, making it affordable for farmers in the UK and worldwide. The project, called POLIDAR, will run from 2024 to 2025. Dr Sergeyev said: “Aston University’s patented technique will be modified by using a laser emitting four time-delayed pulse trains with different states of polarisation. By comparing the input states of polarisation and states of polarisation of light reflected from plants, it will reveal information about the distance to plants and plants' leaf texture, such as water stress and pathogen infection. Unlike state-of-the-art solutions we suggest an all-fibre design with a minimum number of bulk components that reduces the footprint, cost and weight. Dr Sergeyev added: “My project's motivation is driven by the global and UK agenda on increased food production, requiring novel remote sensing approaches towards ICT farming. “As declared at the World Summit on Food Security in 2017, the growth in the world's population requires increased and more efficient agricultural production. “Remote sensing is an essential tool to systematically address the challenging task of enhanced agricultural efficiency by providing real-time information about crop traits for yield estimation.” The announcement coincides with UNESCO Day of Light which marks the role light plays in science, culture and art, education and sustainable development. It is held on 16 May every year, the anniversary of the first successful operation of a laser. ENDS World Summit on Food Security in 2017 The future of food and agriculture: Trends and challenges (fao.org) https://www.fao.org/3/i6583e/i6583e.pdf UNESCO Day of Light The International Day of Light is a global initiative that provides an annual focal point for the continued appreciation of light and the role it plays in science, culture and art, education, and sustainable development, and in fields as diverse as medicine, communications, and energy. The broad theme of light will allow many different sectors of society worldwide to participate in activities that demonstrates how science, technology, art and culture can help achieve the goals of UNESCO – education, equality, and peace. The International Day of Light is held on May 16th every year, the anniversary of the first successful operation of the laser in 1960 by physicist and engineer, Theodore Maiman. The laser is a perfect example of how a scientific discovery can yield revolutionary benefits to society in communications, healthcare and many other fields. About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Clary Collicutt and Professor Rachel Shaw join the latest episode of Aston Originals Health Matters series Clary’s PhD research investigates the mental health benefits of urban walking The theme of Mental Health Awareness Week 2024, from 13 to 19 May, is ‘moving more for our mental health’. Two researchers from Aston University’s School of Psychology discuss the mental health benefits of urban walking in the latest Aston Originals Health Matters podcast, recorded for Mental Health Awareness Week 2024. Clary Collicutt is a PhD researcher, with her project specifically looking at urban walking. While there is much in the literature about the benefits of walking in nature and the countryside, very little exists about urban walking. Professor Rachel Shaw is director of the Applied Health Research Group and wellbeing lead for the College of Health and Life Sciences at Aston University, and Clary’s PhD supervisor. The theme of Mental Health Awareness Week 2024 is ‘moving more for our mental health’. Movement, whether that’s going for a walk, dancing in the kitchen or playing a sport, has been shown to increase energy levels, reduce stress and anxiety, and boost self-esteem, and the Mental Health Foundation is seeking to encourage more people to find ‘moments for movement’. One of the easiest ways to get moving is simply to go for a walk, and with many more people living in towns and cities, this is most likely to be around urban streets and roads. Clary’s PhD research is an extension of her MSc studies and is a qualitative look at how urban walking can help mental health. While a quantitative study would look at numbers and statistics, the qualitative research will allow Clary to connect with people’s stories and personal experiences. As part of her research, Clary is interviewing people about walking and what they feel it does for them. One interviewee told Clary that she views her urban walking like a “prescription”, something she needs to do every day, while another plays Pokémon Go, which he finds an incentive to walk further. Meanwhile, Professor Shaw has been researching wellbeing in paediatric critical care (PCC) staff, who face hugely stressful working conditions. One fact that has come out time and again is how important walking is, even if only a wander round the block in a break. Clary said: “Talking about urban walking, one of the main advantages is the complete accessibility of it, I think. “I personally find walking a magic tonic. You can feel really stressed and then you can have a walk and I feel that really helps me. Or I can feel really good and have a walk and it will still help me. So, wherever the mood spectrum is, I think walking can benefit.” The full podcast can be accessed on YouTube.
300 million tonnes of rice straw are burned after harvest in Asia every year Aston University will be contributing to new international project to unlock renewable energy potential Its researchers will lead on calculating the greenhouse gas emissions savings of new systems. Aston University researchers are helping to make rice straw processing in India and the Philippines less environmentally damaging. The University will be contributing to a new international collaboration, the Renewable, Inclusive Carbon-negative Energy (RICE) project, funded by Innovate UK Energy Catalyst programme to unlock renewable energy for rice farmers. Already the University has worked with UK company Straw Innovations in the Philippines and now the two are expanding their collaboration to benefit more of the continent. Aston University working with UK company Straw Innovations and Indian enterprise, Takachar Rice straw is a crop waste byproduct and each year across Asia 300 million tonnes of it go up in smoke when burnt after harvest. This releases emissions and air pollutants that triple risks of increased respiratory diseases and accelerate climate change. India and the Philippines are the world’s second and eighth largest rice producers respectively and together they produce 130 million tonnes of both rice and straw per year. Aston University and Straw Innovations and will be collaborating with an Indian award winning small and medium sized enterprise, Takachar. The firm has developed small scale, low-cost, portable equipment which can convert agricultural waste on-site into higher value bioproducts such as fertilizer blends, chemicals and biofuels. "The company will develop a super-sized version which is 10 times bigger than their current device, make it adaptable to rice mills, and will send it to Straw Innovations, so the two firms can test out different business models for farmer adoption/benefit. Straw Innovations will also send their machines from the Philippines to India mid-project and the two countries will test out different business models for farmer adoption/benefit. And for the first time they will tap into the heat produced in the waste process to dry rice, instead of using diesel or kerosene. University researchers will lead on assessing the sustainability of the project, calculating the greenhouse gas emissions savings of the new systems introduced by Straw Innovations and Takachar. Sustainability expert Dr Mirjam Röder will also engage with the farming community and rural stakeholders to quantify how the systems can increase farmer incomes, equality of opportunity, food security and decarbonisation benefits, whilst highlighting any trade-offs. Dr Röder who is based at Aston University’s Energy & Bioproducts Research Institute (EBRI) said: “Environmentally, rice produces 48% of all global crop emissions, due to methane from flooded fields. This is halved when the straw is removed and reduced further when its carbon is stored in biochar. We are aiming for carbon negative which means removing carbon dioxide (CO₂) from the atmosphere or sequestering more CO₂ than is emitted. “Our new research leads on from our rice straw bio gas hub project with Straw Innovations, SEARCA and Koolmill and we’re pleased to be building further relationships with new partners in India. In January Biomass and Bioenergy published a paper about the topic written by Dr Röder, the director of EBRI Professor Patricia Thornley and Craig Jamieson of Straw Innovations called The greenhouse gas performance and climate change mitigation potential from rice straw biogas as a pathway to the UN sustainable development goals. Craig Jamieson from Straw Innovations said "We’ve been pioneering rice straw work with the team at Aston University for the past seven years. We're delighted to continue that strong partnership and widen it to include Takachar in this new project. “Takachar is a leader in making biochar from crop residues and our partnership with them is very strategic. We look forward to combining our new improved straw harvesting technology with their scaled-up biochar production. It will be a step change, creating a new, more efficient system for carbon negative energy and soil improvement for rural communities across Asia." Vidyut Mohan who founded Takachar said: “We are excited to partner with Aston University and Straw Innovations. “Our combined solutions can significantly move the needle in reducing crop residue collection costs and biochar production costs for carbon removal." Notes to Editors Rice straw is a crop waste byproduct and each year across Asia 300 million tonnes of it go up in smoke when burnt after harvest https://tinyurl.com/2afjhhsj To read The greenhouse gas performance and climate change mitigation potential from rice straw biogas as a pathway to the UN sustainable development goals visit https://www.sciencedirect.com/science/article/pii/S0961953424000254, Biomass and Bioenergy Volume 182, March 2024, 107072 Mirjam Röder and Patricia Thornley Energy & Bioproducts Research Institute (EBRI), College of Engineering and Physical Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, United Kingdom Craig Jamieson Straw Innovations Ltd., Lawes Open Innovation Hub, Rothamsted Research, West Common, Harpenden, HERTS, AL5 2JQ, United Kingdom https://doi.org/10.1016/j.biombioe.2024.107072 About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Homes heated by human sewage could be a reality thanks to Aston University
Project to transform sewage sludge into clean water and energy awarded a share of £4.5 million by Ofwat Involves extracting energy from the waste produced during sewage and water treatment Gases obtained can be used to power engines or heat people’s homes. An Aston University project that could transform sewage sludge into clean water and energy has been awarded a share of £4.5 million by Ofwat. The University project with engineering consultancy ICMEA-UK involves extracting energy from the waste produced during sewage and water treatment and transforming it into hydrogen and/or methane. The gases can then be used to power engines or heat people’s homes. The aim is to create a sustainable and cost-efficiently run wastewater processes, plus extra energy. The initiative was one of ten winners of Ofwat’s Water Discovery Challenge, of which the Aston University scientists and two industrial partners have been awarded £427,000. Dr Jude Onwudili based at Aston University’s Energy and Bioproducts Research Institute (EBRI) is leading the team of scientists who will work with the partners to develop a trial rig to transform solid residues from wastewater treatment plants to hydrogen and/or methane. The two-stage process will involve the initial transformation of organic components in the sludge into liquid intermediates, which will then be converted to the fuel gases in a second stage. The project is called REvAR (Renewable Energy via Aqueous-phase Reforming), and Dr Onwudili will be working with lead partner and engineering consultancy company ICMEA-UK Limited and sustainable infrastructure company Costain. REVAR combines the use of hot-pressurised water or hydrothermal conditions with catalysts to achieve high conversion efficiency. The technique can treat sewage sludge in just minutes, and it is hoped that it will replace existing processes. In 2013, a Chartered Institution of Water and Environmental Management report stated that the sector is the fourth most energy intensive industry in the UK. Dr Onwudili said: “This project is important because millions of tonnes of sewage sludge are generated in the UK each year and the water industry is struggling with how to effectively manage them as waste. “Instead, they can be converted into valuable feedstocks which are used for producing renewable fuel gases, thereby increasing the availability of feedstocks to meet UK decarbonisation targets through bioenergy. “We will be taking a waste product and recovering two important products from it: clean water and renewable energy. Overall, the novel technology will contribute towards meeting UK Net Zero obligations by 2050 and ties in with the University’s purpose to make our world a better place through education, research and innovation.” The Water Discovery Challenge aims to accelerate the development and adoption of promising new innovations for the water sector. Over the next six months, winners will also receive non-financial support and will be able to pitch their projects to potential water company partners and/or investors. The 10 winning teams are from outside the water industry and were chosen because of their projects’ potential to help solve the biggest challenges facing the sector. The competition is part of the Ofwat Innovation Fund, run by the water regulator Ofwat, with Challenge Works, Arup and Isle Utilities and is the first in the water sector to invite ideas from innovators across industries. Helen Campbell, senior director for sector performance at Ofwat, said: “This competition was about reaching new innovators from outside the sector with different approaches and new ideas, and that’s exactly what the winners are doing. “The products and ideas recognised in this cross-sector challenge will equip water companies to better face challenges of the future – including achieving sustainability goals and meeting net zero targets – all while providing the highest-quality product for consumers.” ENDS A Blueprint For Carbon Emissions Reduction in the UK Water Industry The Chartered Institution of Water and Environmental Management https://www.ciwem.org/assets/pdf/Policy/Reports/A-Blueprint-for-carbon-emissions-reductions-in-the-water-industry.pdf Ofwat Innovation Fund Ofwat, the Water Services Regulation Authority for England and Wales, has established a £200 million Innovation Fund to grow the water sector’s capacity to innovate, enabling it to better meet the evolving needs of customers, society and the environment. The Innovation Fund, delivered in partnership with Challenge Works (formerly known as Nesta Challenges) and supported by Arup and Isle Utilities, is designed to complement Ofwat’s existing approach to innovation and to help deliver against Ofwat’s strategy which highlights the role of innovation in meeting many of the challenges the sector faces. About ICMEA-UK Based in Sheffield, in the North of England, ICMEA-UK is the UK arm of an established Italian innovative engineering company - ICMEA SRL. They are an innovative Engineering consultancy company, and work in partnership with a range of other organisations to provide innovative, bespoke solutions to problems where an Engineering solution is required. About Costain Costain helps to improve people’s lives by creating connected, sustainable infrastructure that enables people and the planet thrive. They shape, create, and deliver pioneering solutions that transform the performance of the infrastructure ecosystem across the UK’s energy, water, transportation, and defence markets. They are organised around their customers anticipating and solving challenges and helping to improve performance. By bringing together their unique mix of construction, consulting, and digital experts they engineer and deliver sustainable, efficient, and practical solutions. About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Researcher develops microrobots to battle cancer with unique precision
Magnetic robots that can target cancer cells are nothing new. But the patented microrobots developed by the University of Delaware's Sambeeta Das can be guided with a magnetic field to deliver medication to cells – or to destroy infectious cells, such as cancer – inside the body. To mark the launch of National Inventors Month, Das, assistant professor of mechanical engineering, shared her journey toward invention. Q: Tell us about your patented invention on microrobots for cancer research. What problem were you trying to solve? Das: One of the biggest issues with cancer research is the ability to target cancer cells without harming healthy cells. Cancer cells are sneaky, and they have evolved ways of hiding from the body’s immune cells. A big part of our research focuses on targeting, specifically precision targeting. We want to be able to target a single cell in a mass of cells, whether that is a single cell in a mass of cancer cells or whether it is a single abnormal cell surrounded by healthy cells. To do this, we use magnetic microrobots that can be driven inside the body by magnetic fields to a particular cell location. Magnetic fields are biocompatible, meaning they are not harmful to biological tissues, and our microrobots are very small, around 20 microns, which is about the size of a single bacteria cell. We can load our microrobots with various drugs and modify their surface in such a way that when the robots come in contact with the cells we are targeting, they can kill the target cell or perform some other function. Q: How is this solution unique? Das: Other people have made magnetic microrobots, but our system is unique since it allows us to do automatic targeting with a lot of precision. For example, a person operating our microrobots can just point to a cell and our system will drive the microrobot there. Additionally, the instrument we have made and patented is an all-in-one portable device that can be used anywhere. We don’t need a separate microscope, camera or software, it is all built in and very user friendly. Anyone can use it. This makes it super portable, which means quick solutions for health practitioners. In addition, poor and resource challenged areas can also be accessed with this portable solution. Q: What drives you toward invention? Das: I like to solve problems, and I like seeing something come together from nothing. I am very interested in problems that affect human health and longevity, particularly those that affect the common person. Q: How do you approach solving a problem, and whose support has been critical along the way? Das: One thing I have realized is that it is imperative to ask the right question to solve a problem. You must really get to the core of the issue. The second thing is to always keep the end user in mind. So, it’s kind of a two-pronged approach—looking from both ends of the problem. For support, I would say my team members and my collaborators. Their support has been invaluable in helping me solve the problems that I want to solve. In fact, my graduate students keep a running list of crazy ideas that they have come up with. It helps us look at problems in a unique way and come up with innovative solutions. Q: Not every invention makes it. How do you deal with failure? Das: The way that I start working on a problem is to assume that whatever we do, we are going to fail. I always tell my students that their first couple of experiments or designs will always fail. But failure is essential because it will teach you what not to do. And knowing what not to do is sometimes the critical part of the invention process. The failures inform us about the ways of not doing something which means now there is another way of doing something. Q: What is the best advice you’ve ever received? Das: The best career advice I’ve ever received is that there is always another way. If you run into roadblocks there is always another answer, there is always another opportunity. So we just need to keep going and trying new and crazy ideas. Q: How are inventive minds created – is it innate or can it be developed? How do you encourage innovation among your students? Das: That’s an interesting question and honestly, I am not sure. I do believe in what Edison said, “Genius is 1% inspiration and 99% perspiration.” He is a known inventor, so I would go with his interpretation on this. As for my students, I give them lots of freedom. I think freedom is essential in encouraging innovation. The freedom to come up with crazy ideas without anyone saying that won't work and the freedom to fail—multiple times. Das is available for interviews to talk about her microrobots and other projects at UD. To reach her, visit her profile and click the "contact" button.
A monumental anniversary approaches as we commemorate the 1931 opening of the Empire State Building, an architectural marvel that has stood as an emblem of innovation and human achievement for nearly a century. Beyond its towering presence on the New York City skyline, this anniversary is a poignant moment to reflect on the enduring legacy of this iconic structure and its resonance with the public, encapsulating themes of perseverance, ingenuity, and urban development. Here are several compelling story angles that journalists may find ripe for exploration: Historical significance and architectural marvel: Delve into the fascinating backstory of the Empire State Building, exploring the engineering feats and human endeavor that brought this skyscraper to life. Evolving skyline and urban identity: Examine how the Empire State Building has shaped the cultural and visual landscape of New York City, and its enduring significance in an ever-changing metropolis. Sustainable initiatives and environmental impact: Explore the building's initiatives toward sustainability and energy efficiency, offering insights into its role as a model for sustainable urban development. Economic impact and tourism: Investigate the economic impact of the Empire State Building on local communities, tourism, and its enduring appeal as a global tourist destination. Cultural resonance and popular culture: Uncover the building's rich cultural legacy, from its appearances in film, literature, and art, to its symbolic significance in popular imagination. Preservation efforts and historical conservation: Shed light on ongoing efforts to preserve and maintain the architectural integrity and historical significance of this iconic landmark for future generations. Connect with an Expert about Architecture and the Empire State Building: Dana Cupkova Associate Professor · Carnegie Mellon University Richard Campanella Associate Dean for Research, Senior Professor of Practice - Architecture and Geography · Tulane University Eric Corey Freed Founding Principal · OrganicARCHITECT Peter Christensen Arthur Satz Professor of the Humanities and Professor of Art History · University of Rochester Dennis Shelden Director, Center for Architecture Science and Ecology (CASE) · Rensselaer Polytechnic Institute To search our full list of experts visit www.expertfile.com Photo Credit: Ben Dumond
