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Dinosaurs in New Mexico Thrived Until the Very End, Study Shows
For decades, many scientists believed dinosaurs were already dwindling in number and variety long before an asteroid strike sealed their fate 66 million years ago. But new research in the journal Science from Baylor University, New Mexico State University, the Smithsonian Institution and an international team is rewriting that story. The dinosaurs, it turns out, were not fading away. They were flourishing. A final flourish in the San Juan Basin In northwestern New Mexico, layers of rock preserve a hidden chapter of Earth’s history. In the Naashoibito Member of the Kirtland Formation, researchers uncovered evidence of vibrant dinosaur ecosystems that thrived until just before the asteroid impact. High-precision dating techniques revealed that fossils from these rocks are between 66.4 and 66 million years old – placing them in the catastrophic Cretaceous-Paleogene boundary. “The Naashoibito dinosaurs lived at the same time as the famous Hell Creek species in Montana and the Dakotas... They were not in decline – these were vibrant, diverse communities.” – Daniel Peppe, Ph.D. “The Naashoibito dinosaurs lived at the same time as the famous Hell Creek species in Montana and the Dakotas,” said Daniel Peppe, Ph.D., associate professor of geosciences at Baylor University. “They were not in decline – these were vibrant, diverse communities.” Dinosaurs in their prime The New Mexico fossils tell a different story than originally thought. Far from being uniform and weakened, dinosaur communities across North America were regionally distinct and thriving. Using ecological and biogeographic analyses, the researchers discovered that dinosaurs in western North America lived in separate “bioprovinces,” divided not by mountains or rivers, but by temperature differences across regions. “What our new research shows is that dinosaurs are not on their way out going into the mass extinction,” said first author Andrew Flynn, Ph.D., ‘20, assistant professor of geological sciences at New Mexico State University. “They're doing great, they're thriving and that the asteroid impact seems to knock them out. This counters a long-held idea that there was this long-term decline in dinosaur diversity leading up to the mass extinction making them more prone to extinction.” Life after impact The asteroid impact ended the age of dinosaurs in an instant – but the ecosystems they left behind set the stage for what came next, the researchers said. Within 300,000 years of their extinction, mammals began to diversify rapidly, exploring new diets, body sizes and ecological roles. The same temperature-driven patterns that shaped dinosaur communities continued into the Paleocene, showing how climate guided life’s rebound after catastrophe. “The surviving mammals still retain the same north and south bio provinces,” Flynn said. “Mammals in the north and the south are very different from each other, which is different than other mass extinctions where it seems to be much more uniform.” Why the discovery matters today The discovery is more than a window into the past – it’s a reminder of the resilience and vulnerability of life on Earth. Conducted on public lands managed by the U.S. Bureau of Land Management, the research highlights how carefully protected landscapes can yield profound insights into how ecosystems respond to sudden global change. With a clearer understanding of the timeline of the dinosaurs’ final days, the study reveals not a slow fade into extinction but a dramatic ending to a story of flourishing diversity cut short by cosmic chance.
A Roadmap or a Rift? Examining Trump’s 28-Point Ukraine Peace Proposal
As negotiations around the war in Ukraine continue to dominate global headlines, a newly surfaced 28-point peace proposal associated with former U.S. President Donald Trump has triggered intense debate across NATO capitals, Kyiv, and Moscow. The document — described in reporting by Reuters, Axios, Sky News, Al Jazeera and other outlets — outlines a framework aimed at ending the conflict but includes provisions that many analysts say could significantly reshape Europe’s security landscape. A Plan Built Around Ceasefire, Guarantees, and Reconstruction At its core, the plan calls for a formal ceasefire, a non-aggression pact between Russia, Ukraine, and European states, and a set of “security guarantees” meant to deter future conflict. Reporting indicates that Ukraine would receive assurances that any renewed Russian offensive would trigger a coordinated international response. The plan also proposes the creation of a major reconstruction program — potentially financed in part with frozen Russian assets — to rebuild infrastructure and modernize Ukraine’s economy. The proposal references pathways for deeper Ukrainian integration with Europe, including support for progressing toward EU membership and providing enhanced access to European markets. A large “Ukraine Development Fund” is also mentioned in multiple summaries of the plan. Provisions Driving the Most Global Pushback The most controversial elements relate to Ukraine’s territorial integrity and long-term security posture. Outlets such as Sky News and Al Jazeera report that the draft would recognize Russian control over Crimea and large parts of Donetsk, Luhansk, Zaporizhzhia, and Kherson — areas currently occupied by Russian forces. Ukraine would also be required to formally abandon NATO membership and cap its military at 600,000 personnel. Additional provisions include restrictions on the presence of foreign troops in Ukraine, phased lifting of sanctions on Russia, full amnesty for war-related actions, and the reintegration of Russia into global economic and political structures. These components have drawn sharp responses, particularly from European leaders who argue the plan could reward aggression and undermine international legal norms. Dr. Glen Duerr is a citizen of three countries. He was born in the United Kingdom, moved to Canada as a teenager, and then to the United States to obtain his Ph.D. His teaching and research interests include nationalism and secession, comparative politics, international relations theory, sports and politics, and Christianity and politics. View his profile. What Remains Unclear or Still Under Discussion Reporting from Reuters and AP notes that many sections of the plan remain undefined or are still in flux. The exact mechanism behind the proposed security guarantees is not detailed. Oversight of reconstruction funds, timelines for reintegration of Russia, and the legal handling of frozen assets also require further clarification. Some reporting suggests parts of the plan draw from a prior informal Russian “non-paper,” raising questions about the provenance and intent of specific provisions. Why the Proposal Matters With the war approaching four years of fighting, any formal proposal for ending hostilities carries significant geopolitical weight. Supporters of the plan frame it as a pragmatic attempt to halt loss of life and begin rebuilding. Critics argue it risks legitimizing territorial conquest and weakening the broader post-Cold-War security order. As governments evaluate the implications, journalists covering defense, diplomacy, and international law will find this evolving proposal central to understanding where U.S., European, Russian, and Ukrainian negotiators may — or may not — be willing to go next.
Giving with Purpose This Holiday Season
As the season of giving draws near, many people are searching for meaningful ways to support the causes that matter most. From local food banks to global humanitarian organizations, charitable giving offers an opportunity to make a genuine difference – for the organization and for the donor. Two Baylor University experts in consumer behavior and philanthropy – James A. Roberts, Ph.D., The Ben H. Williams Professor of Marketing in the Hankamer School of Business, and Andrew P. Hogue, Ph.D., associate dean in the Office of Engaged Learning and founder of Philanthropy and the Public Good program – share five practical strategies to help donors give with intention and impact. Five ways to give more thoughtfully and effectively 1. Choose a cause that resonates with you Begin by considering the issues that matter most –education, hunger, health care, the environment or another area close to your heart. Once you identify your passion, take time to research organizations working in that space. Look for transparency, measurable results and a strong record of directing funds to mission-focused programs. “A helpful shortcut is to see whether a nonprofit receives repeat grants from charitable foundations,” Hogue said. “Those grants typically follow a rigorous evaluation process.” 2. Decide what you can comfortably give Giving should feel fulfilling, not stressful. Roberts and Hogue recommend reviewing your household budget and determining an amount that fits comfortably. Even small donations can accumulate into meaningful support over time. 3. Consider how often you want to give Think about whether a single contribution or ongoing support works best for you. Regular giving helps nonprofits plan ahead and maintain steady programming. “Consistent donations allow charities to allocate resources more effectively throughout the year,” Hogue said. 4. Automate your contributions Setting up recurring gifts through your bank or directly with a nonprofit keeps your generosity on track with minimal effort. Automatic withdrawals ensure reliability for the organization and ease for the donor. “It’s a simple way to make sure you don’t forget to give,” Roberts said, “and it provides charities with predictable support.” 5. Offer your time and talent if money is tight Financial support is just one form of generosity. Time, skills and personal networks can be equally valuable. “Donating your time and skills can be just as impactful,” Roberts said. “Whether you’re mentoring, sorting donations or helping at events, your presence matters.” Hogue added that giving enriches both the recipient and the giver: “Charitable giving is about making a difference in others’ lives while adding purpose and connection to your own.” His advice: start small, stay consistent and simply take the first step. “Giving is deeply rewarding,” Hogue said. “And as you grow in your generosity, keep a beginner’s mindset – there is always room to improve how we steward the resources entrusted to us.” Looking to know more or arrange an interview? Simply click on the expert's icon below or contact: Shelby Cefaratti-Bertin today.
Nandi A. Marshall, DrPH, professor and associate dean for Georgia Southern University’s Jiann-Ping Hsu College of Public Health, has been named president of the American Public Health Association (APHA), the nation’s oldest and largest organization of public health professionals. Marshall began her presidential term on Nov. 5, following a year as president-elect. She will serve a three-year term on APHA’s executive board, including her current presidential year and a subsequent year as immediate past president. With more than two decades of experience in community-engaged public health, Marshall is widely recognized for her leadership in advancing maternal and child health equity, and for her dedication to preparing the next generation of the public health workforce. She holds a bachelor’s in religious studies from Spelman College, a master’s in public health from East Stroudsburg University and a Doctor of Public Health from Georgia Southern. “Dr. Marshall’s appointment to lead APHA is a tremendous national recognition of her contribution to public health — and a reflection of Georgia Southern’s growing impact on the global public health landscape,” said Avinandan Mukherjee, Ph.D., provost and executive vice president for Academic Affairs. “Her commitment to community partnership, workforce development and health equity exemplifies the values we strive to instill in every graduate of our distinctive public health college.” Marshall’s work has centered on bridging lived experience and scientific research to drive equitable health outcomes. “I’m deeply honored to serve as APHA president,” Marshall said. “Public health calls us to listen to communities, honor their wisdom and work together to build the equitable systems that recognize health as a human right. Equity is not an outcome — it’s a commitment. And I’m grateful to continue this work with purpose, courage and love alongside partners across the country.” Founded in 1872, APHA represents more than 25,000 members nationwide, serving as a convener, catalyst and advocate for equitable health and well-being for all. The association connects practitioners, researchers, educators and policymakers to advance evidence-based public health initiatives. Looking to know more about Georgia Southern University or connect with Dr. Marshall — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
One AI-based advancement at a time, UF leaders are transforming the sports industry
As emerging technologies like AI reshape sport industries and professional demands evolve, it is essential for students to graduate with the expertise to thrive in their future careers. To ensure that these students are set up for success, the UF College of Health & Human Performance has launched a new sports analytics program. Led by Scott Nestler, Ph.D., CAP, PStat, a professor of practice in the Department of Sport Management and a national analytics and data science expert, the program ties back to the UF & Sport Collaborative – a five-part project intended to elevate UF’s presence on the global stage in sports performance, healthcare and communication. “Tools and insights that previously were only available to professional sports teams are now coming to the college level, and it makes sense for universities to begin using these data, technologies and new analytic methods,” Nestler said. The sports analytics program fosters collaboration between academic units, such as the Warrington College of Business and the University Athletic Association, helping bridge the gap between sport research and innovation and empowering students to address real-world challenges through data and AI. For example, the program offers opportunities to leverage technology and analytics for strategic decision making in player acquisition, team formation and in-game decisions. Beyond performance metrics, the program also explores marketing strategies and revenue analytics, providing a well-rounded understanding of the field. “When you have enough data and a large enough sample of individuals, AI can help make predictions that otherwise would take prohibitively longer for a human to accomplish with traditional methods,” said Garrett Beatty, Ph.D., the assistant dean for innovation and entrepreneurship and an instructional associate professor in the College of Health & Human Performance’s Department of Applied Physiology and Kinesiology. “Because those data volumes are getting so large, AI models, machine learning, deep learning and other strategies can be leveraged to make sense and glean insights from sport and human performance data in ways that have never been done before.” The program seeks to offer several educational opportunities, such as individual courses, certificate programs and potentially a full degree program. In the long term, Nestler envisions the program evolving into a center or institute, beginning with establishing a research lab in the spring. Additionally, the program will leverage the university’s supercomputer, HiPerGator, to analyze larger data sets and use newer predictive modeling machine learning algorithms. “As faculty and staff move from working with box score and play-by-play data to using tracking data, which contains coordinates of all players and the ball on the field or court tens of times per second, the size of data files in sports analytics has grown tremendously,” Nestler said. “HiPerGator, with its large storage capacity and multiple central processing units/graphic processing units, is ideal for using in sports analytics work in 2025.” Nestler also aims to increase student involvement by enhancing UF’s Sport Analytics Club and hiring research assistants to work on projects for the University Athletic Association. “We need to take a broader view of what AI is and realize that it incorporates a lot of what we’ve been calling data science and analytics in the form of machine learning models, which came more out of statistics and computer science. Those are types of AI and those that I think will largely continue to be used in the coming years within the sports space,” Nestler said. “Also, we’re continuing to see growth in the number of people interested in working in this space, and I don’t foresee that changing. Fortunately, we are also seeing the number of opportunities available to those with the appropriate skills increase as well.”
Trump’s Threat is His Destruction of the Republican Party
In All the King’s Men, Robert Penn Warren describes Willie Stark’s final victory. “And there wasn’t any Democratic party. There was just Willie, with his hair in his eyes and his shirt sticking to his stomach with sweat. And he had a meat ax in his hand and was screaming for blood.” Warren’s description is darkly poetic and metaphorical. Stark, the populist governor of a fictional state, did not murder his rivals, but he did destroy them, along with the political party he rode to power. Like Stark, Donald Trump has carved up the Republican Party of old, and in its place, there is just Trump. This is not the first time a politician has remade a political party, but the death of the G.O.P. threatens to unbalance our political system. We are defined by close elections, tight legislative majorities, and polarized preferences. Neither side in the cultural conflict can achieve core objectives, so the temptation to put more hope and power into the Executive, to skew the system, is mounting. We can argue about the degree to which past Republicans were truly restrained, especially in government spending, but at least the G.O.P. used to advocate for two seatbelts to keep the body politic safe from accidents: character to govern the self and constitutionalism to limit what government can do to others. As the G.O.P. grew to rival Democratic power, in the 1980s and 1990s, the New Deal coalition fractured, along with the assumption that simply more power, expertly applied, could solve our problems. Democrat Bill Clinton conceded “the era of big government is over.” Justice Elena Kagan recognized, “we’re all textualists now.” The tug of war between an evolving progressivism and a robust conservatism may not have made for an ideal way to solve problems, but it did encourage humility, born of the recognition that radical actions, even if successful, would be punished. Dr. Mark Caleb Smith serves as Professor of Political Science and the Director of the Center for Political Studies at Cedarville University. He teaches courses in American Politics, Constitutional Law, and Research Methodology/Data Analysis. His primary research interest is in the field of religion and American politics. View his profile Those days are over. Donald Trump’s Republicans are no longer a restraint of any kind. The seatbelts of the past have been snipped by the same leaders who claimed to buckle them in place. The Epstein Files are the exception of congressional pushback that proves the rule of the party’s degradation. But what of the appointment of unqualified and incompetent leaders in the F.B.I., H.H.S., Homeland Security, and the Department of Defense? Illegal and extra-judicial killings in the Caribbean? An unexplained and unauthorized military buildup in the same region? Shakedowns of universities and media outlets? Crypto corruption? Tariffs? Strong-arming law firms and firing career civil servants for seeking justice in our courts? The Republican response has mostly been crickets. There is no longer a major party that pretends to restrain the president through the law out of principle. The real disagreement between Trump Republicans and Biden Democrats is not about should the president abuse his power, but how. Unless something dramatic happens, the politics of the meat ax will come for us all. Mark is available to speak with the media regarding the state of politics in America. Simply click on his icon now to arrange an interview.
Budget 25 – initial reactions related to personal financial wellbeing
As the director of the Aston Centre for Personal Financial Wellbeing, and a professor of taxation, I obviously take particular interest in the annual budget day as it sets a tone for much of the personal finance changes that are likely to occur in the near future. The lead up to this year’s budget had unprecedented levels of speculation with much of the press and commentators trying to get attention with ever more it seemed wilder guessing of what the chancellor might do – largely unhelpfully and worrying people and the markets unnecessarily. Almost all of this proved wide of the mark as the budget didn’t increase any of the main taxes at all, and where it might nudge National Insurance contributions (NICs) up for some, this won’t be for a few years and only in a small area (pension payments for employees) that won’t actually affect most people. Small and cautious steps to reform The reason for all this speculation of key changes needed was that everyone suspected there was a big hole in the national finances. This was shown not to be the case. In fact, predictions provided in the budget documents are we’d in fact be in budget surplus by the end of this parliament period even before the changes announced take effect. This was a surprise to many and meant the chancellor could actually focus on at least some small and cautious steps towards reforming how our tax, benefit and government spending systems work. What she proposed therefore is currently predicted will raise circa £26bn and give the government ‘head-room’ to cope with economic changes later rather than needed to fill a feared financial black hole now – good news all round! This meant what we actually got was lots of smaller changes with fewer ‘rabbit out of a hat’ big tax surprises than we have had in recent years – a welcome steadying trend I hope will continue. She also promised some short-term spending that can be paid for with a combination of extra borrowing now and with increased taxes later – again a trend of recent budgets. If these tax changes actually happen in the end, then it will be down to what happens between now and when these were proposed to commence – by no means a guarantee these will ever happen. Later budgets, or other rule changes in the future, could easily retract or counter them (all chancellors like to announce planned tax changes aren’t going to happen for obvious political gain reasons!). Income tax changes The largest share of the extra £26bn raised will come from extending the income tax thresholds for a further period – now to 2031. These have been fixed (at £12,570 for example for the point at which income tax starts to need to be paid on personal incomes) since at least 2023, some well before this. This matters, as, when wages rise due to inflation, people are not better off in reality (you get more income but things cost more), but may end up paying more tax than before as the thresholds haven’t increased with inflation to the same degree (what we call ‘fiscal drag’). As such, holding these thresholds fixed for longer will raise extra money for the government (predicted to be over £12bn a year in 2030-31 for example) – largely unnoticed as to many it doesn’t feel like the tax rise it clearly is. The threshold fixing extension announced today will mean that as many as 700,000 more people will start to pay some income tax when they wouldn’t currently, and up to 1 million more people will start to pay higher rates of tax than currently – all without being actually better off in real terms. Some call this stealth tax, but it feels very real when it starts to affect you if your total taxable incomes fall near these threshold levels. There were in total more than 70 other tax measure changes in this budget – a huge number and lots to get your head around. However, most of these will not affect most people and are relatively small in nature – targeted at making the tax system a little fairer (i.e. those on higher incomes, with more savings, dividends, receiving additional income from property they own etc – paying more taxes as a proportion of the total amount raised in tax from all sources). This is clearly welcome news (at least for those not being asked to pay this extra) in the current climate. The biggest changes for financial wellbeing As a research centre focusing on individual and family financial wellbeing, what do we think are the specifics announcements made that are most likely to affect people – several headline announcements are worth highlighting: - 1. The removal of the two-child limit on benefit eligibility is obviously a key headline – long touted as a key reason larger families are much more likely to be in poverty than smaller families. This is a key change that many Labour MPs wanted to see happen and the chancellor has delivered on it. This is very welcome news – although it won’t start to affect these families until after April 2026 to give time to bring these measures into place – but then predicted to lift 450,000 children out of poverty. 2. As part of making the tax system more progressive, a brand-new tax was announced on very expensive houses in England – to be snappily called the High Value Council Tax Surcharge (or HVCTS) – although expect it to be called the ‘mansion tax’ by everyone! The UK’s main local tax (council tax) isn’t going to be reformed as such in this change – despite being the target of much speculation that it is just too regressive to leave unreformed any longer after we haven’t revalued houses in most of the UK since 1991. This will instead be an additional tax, commencing in April 28, on those whose properties are valued (now) at £2m or more – with higher rates rising to those with properties over £5m. Clearly this will affect relatively few in most of the UK (only expected to affect 1% of properties nationally), but will affect some and will raise extra revenues (expected to raise circa £400m+ a year) to directly support provision of local services – much needed in many parts of the UK. 3. New taxes on electric cars – given fuel duty is not paid by those who drive electric cars (as they don’t buy petrol or diesel) there have been calls for new taxes to be charged to electric car drivers. While these cars may be better for the environment when driven, they continue to wear roads and contribute to congestion. The government is proposing a per mile charge from April 28 (to be called the Electric Vehicle Excise Duty or eVHD) for these vehicles which will be painful for electric car divers – not least as this cost as not known when purchase decisions were made. No-one likes a tax charged on something you have already made the decision to buy so expect this to be unpopular. It is proposed currently to cost EV drivers around £20/month – about half the rate of fuel duty on average – and expected to raise circa £2bn a year by 2030-31. I expect this tax will become more nuanced in future perhaps as technology enables perhaps different charges to be applied to use of congested city roads compared to open rural driving perhaps - we will see. 4. National Insurance deductibility for pension contributions via salary sacrifice schemes operated by many employers for their employees is to be capped at £2,000 (although only from April 29 – so no immediate effect). This now very widely used approach to making pension contributions if you are an employee that in effect avoids you having to pay NIC on this income going into your pension. For those with larger pension contributions the bit that can be made before NIC is due on the extra this will be capped in the future to £2,000 per year – again affecting those who receive higher pension contributions most and affecting those at the bottom of the income spectrum, little if at all (74% of employees are predicted not to be affected). Is this a breach of the Labour manifesto promises not to increase the main taxes? For some it certainly seems that way. What didn’t happen? There are many smaller measures to explore, or ones that are not coming into effect for the next year or more that might have been missed from the news headlines but that will almost certainly affect lots of people. To name just a few (including highlighting several things NOT going to happen – which will obvious not save people money per se, but help by not costing them more): - above inflation increases to national minimum (‘living’) wage for all age groups from April 2026 (+4.1% for those over 21)– although still not raising this to ‘real living wage’ levels. further extension of holding off on the 5p/litre fuel duty rise not increasing prescription charges (staying at £9.90 for the next year) confirming state pension rises by 4.8% from next April (worth £575/year) confirming £150 winter fuel payments again this winter to over 6 million homes freezing regulated rail fares – preventing the usual annual increases from January (the first time this has happened in 30 years) extending the government’s Help to Save scheme to more benefit recipients than previously No immediate impact for most Overall, this is therefore probably a welcome budget for many, those on lower incomes will likely get the most from these measures, if all are applied as proposed, but most won’t see much of an immediate impact immediately – and with the largest benefit likely to all on larger families in receipt of benefits from next April.
Self-Guided Hypnosis Significantly Reduces Menopausal Hot Flashes
Can a simple daily audio hypnosis session help women find relief from one of menopause’s most disruptive symptoms – hot flashes – without medication? A new clinical trial led by Baylor University’s Gary R. Elkins, Ph.D., professor of psychology and neuroscience and director of the Mind-Body Medicine Research Laboratory, suggests it can. By decreasing hot flash frequency and intensity by over 50%, self-guided hypnosis offers a nonhormonal option for the millions of women whose hot flashes interfere with sleep, mood and quality of life. Published in the journal JAMA Network Open, the multicenter randomized clinical trial evaluated the effectiveness of a six-week, self-administered hypnosis program compared to a sham control using white noise. The study enrolled 250 postmenopausal women experiencing frequent hot flashes, including nearly 25% with a history of breast cancer – a group often excluded from hormone-based treatments. “It is estimated that over 25 million women in the United States have hot flashes, with up to 80% of women in the general population reporting hot flashes during the menopause transition, and 96% of women with breast cancer report hot flashes soon after beginning anti-cancer therapy,” Elkins said. “While hormone replacement therapy is highly effective in reducing hot flashes, it is not a safe choice for everyone, and therefore, women need additional safe and effective alternatives.” After six weeks of daily self-hypnosis audio recordings, participants reported a 53.4% reduction in both frequency and intensity of hot flashes, and at the 3-month follow-up, hot flashes were reduced by 60.9% compared to a 40.9% reduction for women in the control group. The guided self-hypnosis intervention had an even larger treatment effect on reducing hot flashes in women with a history of breast cancer (64% reduction after six weeks). Self-guided hypnosis: A breakthrough approach The study is the first to compare self-guided hypnosis with an active control condition (i.e. sham white noise control group), allowing researchers to better understand how much of the benefit came from people’s expectations or the placebo effect. “This was a major breakthrough and innovation, as almost all prior studies of mind-body interventions have only used wait-list, psycho-education or simple relaxation to compare the active hypnotherapy intervention,” Elkins said. “Also, all sessions were self-administered hypnosis, which demonstrated that women could learn how to use hypnosis for hot flashes on their own with support and guidance. Elkins emphasized that self-hypnosis provides benefits that are easily learned and practiced using audio recordings or app-delivered hypnotherapy. “It can be practiced at home without needing to travel for doctor visits, and it is relatively inexpensive compared to in-person sessions,” Elkins said. “Once a person learns how to use self-hypnosis to reduce hot flashes and improve sleep, it can be used for other purposes such as managing anxiety, coping with pain and for stress management.” At the 12-week follow-up, participants in the self-guided hypnosis group showed a 60.9% reduction in hot flashes as well as significantly greater improvements in sleep, mood, concentration and overall quality of life. Nearly 90% of participants in the hypnosis group reported feeling better, compared to 64% in the control group. “We are very excited about the findings from this important study,” Elkins said. “Our ongoing research aims to further determine how self-hypnosis can significantly improve sleep for breast cancer survivors and women in the peri- to post-menopause transition.” Through this and other studies, Elkins and his team have been able to determine that hypnotherapy is the only behavioral intervention consistently shown to reduce the frequency and severity of hot flashes to a clinically significant amount among both post-menopausal women and breast cancer survivors.
Proteins, often called the building blocks of life, play a central role in drug development. When scientists develop new treatments, they must understand how drugs interact with proteins involved in disease mechanisms and with proteins in the human body that influence drug response. Scientists commonly use cryo-electron microscopy (cryo-EM) 3D imaging data to study proteins. While recent advances have enabled higher-resolution images that are easier to analyze, medium-resolution images—which are more difficult to interpret—are still the most common for larger protein complexes. Salim Sazzed, Ph.D., an assistant professor in the computer science department of Georgia Southern University’s Allen E. Paulson College of Engineering and Computing, has been awarded a two-year National Science Foundation grant of about $175,000 to lead a groundbreaking project to develop novel Artificial Intelligence (AI) techniques for determining protein secondary structures from medium-resolution cryo-electron microscopy (cryo-EM) images. Improved modeling from medium-resolution images will help researchers study more proteins efficiently, giving new insights into diseases and potentially guiding the development of new treatments and future drugs. At its core, this research will combine biology and machine learning to study protein structures. The multidisciplinary approach and potential impacts on public health are what most excite Sazzed. “The impetus behind this research is the positive impact on public health and possibly contributing to the biomedical workforce,” he said. “Seeing biology and computer science combine for that kind of impact is incredibly moving.” As the Principal Investigator (PI) for the project, Sazzed will use his expertise in deep learning computer models to focus on a major challenge in structural biology: identifying the two main secondary structures of proteins—the alpha helix and the beta sheet. These structures are critical for a protein’s overall shape and function, but in medium-resolution cryo-EM images they often appear indistinct or lack clear detail, making them particularly difficult to analyze. Sazzed’s research will focus on two main goals. First, he will quantify the variability of alpha helices and beta sheets in medium-resolution images, comparing them to idealized structures. Second, by integrating this structural variability with the image data in a deep learning model, he will aim to generate more precise and accurate representations of protein secondary structures. “When we feed this information into a deep learning model along with the image data, the model should be able to determine protein secondary structures more precisely,” Sazzed elaborated. Sazzed believes students will greatly benefit from this multi-disciplinary approach. In addition to a Ph.D. student, several undergraduate students will be directly engaged in the research. A full-day workshop will also be organized, allowing Georgia Southern students from diverse disciplines to participate. This initiative will build on Georgia Southern’s strong tradition of involving undergraduates in research and will support the University’s recent focus on biomedical and health sciences. “There are many different knowledge areas coming together in this work,” Sazzed said. “It involves computer science, biology, chemistry, and even public health. I look forward to students following the research and exploring these different fields themselves.” Allen E. Paulson College of Engineering & Computing Interim Associate Dean of Research, Masoud Davari, Ph.D., echoes this sentiment and emphasizes its importance to the University’s research profile. “Sazzed’s interdisciplinary research, which bridges the gap between biology and computer science, will foster multidisciplinary research in our college—as it is cutting-edge and potentially groundbreaking in drug development to impact people’s lives nationally and globally,” Davari said. “It’s also well aligned with the college’s strategic research plan—as we make the move to R1 status to be aligned with ‘Soaring to R1,’ which is among the transformational initiatives for the University.” Looking to know more about Georgia Southern University or connect with Salim Sazzed — simply contact Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
The University of Florida’s ‘AI Queen’ is using AI technology to help prevent dementia
To help the 50 million people globally who live with dementia, the National Institute on Aging is finding researchers to develop tech-based breakthroughs that target the disease — researchers like the University of Florida’s “AI Queen.” It’s a fitting nickname for Aprinda Indahlastari Queen, Ph.D., who is applying artificial intelligence technology to study transcranial direct current stimulation, or tDCS — a technique that involves placing electrodes on the scalp to deliver a weak electrical current to the brain — as a possible way to prevent dementia. The assistant professor in the UF College of Public Health and Health Professions’ Department of Clinical and Health Psychology is using UF’s supercomputer, HiPerGator, to perform neuroimaging and machine learning analyses to study how anatomical differences may affect tDCS outcomes. “Investigating working memory in patients with mild cognitive impairment offers an opportunity to understand how cognitive processes are disrupted in the early stages of Alzheimer’s disease,” said Queen, whose study — funded by a National Institute on Aging research career development grant — integrates neuroimaging with information on brain structure that is unique to older adults and those with mild cognitive impairment. Refining the treatment with AI Using neuroimaging, Queen captures real-time changes during tDCS to the parts of the brain associated with working memory, which is the type of memory that allows humans to temporarily keep track of small amounts of information. Think of this as a mental “scratchpad.” Her study includes older adults with mild cognitive impairment as well as individuals who are cognitively healthy. In tDCS, a safe, weak electrical current passes through electrodes placed on a person’s head. The stimulation is being used in research and clinical settings for a variety of conditions and has shown partial success as a nonpharmaceutical intervention that can improve cognitive and mental health in older adults. But tDCS results can vary across individuals, and the suspected cause is both simple and complex: Everyone’s head is different. “One potential reason tDCS may not work for some individuals is the variation in head tissue anatomy, including differences in brain structure,” Queen said. “Since electrical stimulation must travel through multiple layers of tissue to reach the brain, and every individual’s anatomy is unique, these differences likely affect outcomes.” To address this further, Queen is using AI. “Artificial intelligence will play a major role in the modeling pipeline, including constructing individualized head models, conducting predictive analyses to identify which participants will respond to the stimulation, and disentangling multiple individual factors that may contribute to these outcomes,” Queen said. An estimated 10 to 20% of adults over age 65 have memory or thinking problems characterized as mild cognitive impairment. Their symptoms are not as severe as Alzheimer’s disease and other dementias, but they may be at increased risk for developing dementia. “The fact that not all individuals with mild cognitive impairment progress to Alzheimer’s disease emphasizes the need to identify effective interventions that can slow the progression to dementia,” Queen said. “This project presents an opportunity to differentiate between multiple types of mild cognitive impairment and investigate how tDCS affects the brain across these subtypes.” An AI visionary Queen, who joined the UF faculty under the university’s AI hiring initiative, is an instructor in the College of Public Health and Health Professions’ undergraduate certificate program in AI and public health and health care, and the co-chair of the college’s AI Workgroup. She is also the assistant director for computing and informatics at the UF Center for Cognitive Aging and Memory Clinical Translational Research and a member of UF’s McKnight Brain Institute. Queen received her Ph.D. training in engineering with a focus on building and running computational models to investigate medical devices. She experienced a career “a-ha” moment as a postdoc, when she was a co-investigator on a large clinical trial that paired brain stimulation with cognitive training to enhance cognition in older adults. “This experience was transformative for me. I had the chance to interact directly with participants, which was both fulfilling and eye-opening. These interactions allowed me to see the immediate, real-world implications of my work and sparked a passion for pursuing aging research,” Queen said. “I realized that, through this type of research, I could have a more direct impact on addressing age-related challenges, which prompted a shift in my career plans.” The new grant will help Queen further improve her understanding of the neurobiology and progression of Alzheimer’s disease and other dementias. “These experiences will ultimately prepare me to become a well-rounded aging investigator, capable of making meaningful contributions to the field of aging research,” Queen said. She also credits her mentors and collaborators — Ronald Cohen, Ph.D.; Adam Woods, Ph.D.; Steven DeKosky, M.D.; Ruogu Fang, Ph.D.; Joseph Gullett, Ph.D.; and Glenn Smith, Ph.D. — with supporting her as an early career scientist. “It really takes a village to get here!” Queen said.
