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Ask an Expert: Is the "AI Moratorium" too far reaching?
Recent responses to chatGPT have featured eminent technologists calling for a six-month moratorium on the development of “AI systems more powerful than GPT-4.” Dr. Jeremy Kedziora, PieperPower Endowed Chair in Artificial Intelligence at Milwaukee School of Engineering, supports a middle ground approach between unregulated development and a pause. He says, "I do not agree with a moratorium, but I would call for government action to develop regulatory guidelines for AI use, particularly for endowing AIs with actions." Dr. Kedziora is available as a subject matter expert on the recent "AI moratorium" that was issued by tech leaders. According to Dr. Kedziora: There are good reasons to call for additional oversight of AI creation: Large deep or reinforcement learning systems encode complicated relationships that are difficult for users to predict and understand. Integrating them into daily use by billions of people implies some sort of complex adaptive system in which it is even more difficult for planners to anticipate, predict, and plan. This is likely fertile ground for unintended – and bad – outcomes. Rather than outright replacement, a very real possibility is that AI-enabled workers will have sufficiently high productivity that we’ll need less workers to accomplish tasks. The implication is that there won’t be enough jobs for those who want them. This means that governments will need to seriously consider proposals for UBI and work to limit economic displacement, work which will require time and political bargaining. I do not think it is controversial that we would not want a research group at MIT or CalTech, or anywhere developing an unregulated nuclear weapon. Given the difficulty in predicting its impact, AI may well be in the same category of powerful, suggesting that its creation should be subject to the democratic process. At the same time, there are some important things to keep in mind regarding chatGPT-like AI systems that suggest there are inherent limits to their impact: Though chatGPT may appear–at times–to pass the famous Turing test, this does not imply these systems ’think,’ or are ’self-aware,’ or are ’alive.’ The Turing test aims to avoid answering these questions altogether by simply asking if a machine can be distinguished from a human by another human. At the end of the day, chatGPT is nothing more than a bunch of weights! Contemporary AIs–chatGPT included–have very limited levers to pull. They simply can’t take many actions. Indeed, chatGPT’s only action is to create text in response to a prompt. It cannot do anything independently. Its effects, for now, are limited to passing through the hands of humans and to the social changes it could thereby create. The call for a moratorium emphasizes ‘control’ over AI. It is worth asking just what this control means. Take chatGPT as an example–can its makers control responses to prompts? Probably only in a limited fashion at best, with less and less ability as more people use it. There simply aren’t resources to police its responses. Can chatGPT’s makers ‘flip the off switch?’ Absolutely – restricting access to the API would effectively turn chatGPT off. In that sense, it is certainly under the same kind of control humans subjected to government are. Keep in mind that there are coordination problems – just because there is an AI moratorium in the US does not mean that other countries–particularly US adversaries– will stop development. And as others have said: “as long as AI systems have objectives set by humans, most ethics concerns related to artificial intelligence come from the ethics of the countries wielding them.” There are definitional problems with this sort of moratorium – who would be subject to it? Industry actors? Academics? The criterion those who call for the moratorium use is “AI systems more powerful than GPT-4.” What does “powerful” mean? Enforcement requires drawing boundaries around which AI development is subject to a moratorium – without those boundaries how would such a policy be enforced? It might already be too late – some already claim that they’ve recreated chatGPT. There are two major groups to think about when looking for develop regulatory solutions for AI: academia and industry. There may already be good vehicles for regulating academic research, for example oversight of grant funding. Oversight of AI development in industry is an area that requires attention and application of expertise. If you're a journalist covering Artificial Intelligence, then let us help. Dr. Kedziora is a respected expert in Data Science, Machine Learning, Statistical Modeling, Bayesian Inference, Game Theory and things AI. He's available to speak with the media - simply click on the icon now to arrange an interview today.
Aston University and asbestos consultancy to use AI to improve social housing maintenance
• Aston University and Thames Laboratories enter 30-month Knowledge Transfer Partnership • Will use machine-learning and AI to create a maintenance prioritisation system • Collaboration will reduce costs, emissions, enhance productivity and improve residents' satisfaction. Aston University is teaming up with asbestos consultancy, Thames Laboratories (TL) to improve efficiency of social housing repairs. There are over 1,600 registered social housing providers in England, managing in excess of 4.4 million homes. Each of these properties requires statutory inspections to check gas, asbestos and water hygiene, in addition to general upkeep. However, there is not currently a scheduling system available that offers integration between key maintenance and safety contractors, resulting in additional site visits and increased travel costs and re-work. Aston University computer scientists will use machine-learning and AI to create a maintenance prioritisation system that will centralise job requests and automatically allocate them to the relevant contractors. The collaboration is through a Knowledge Transfer Partnership (KTP) - a collaboration between a business, an academic partner and a highly-qualified researcher, known as a KTP associate. This partnership builds on the outcomes of TL’s first collaboration with Aston University, by expanding the system developed for the company’s in-house use - which directs its field staff to jobs. The project team will improve the system developed during the current KTP to enable it to interact with client and contractor systems, by combining an input data processing unit, enhanced optimisation algorithms, customer enhancements and third-party add-ons into a single dynamic system. The Aston University team will be led by Aniko Ekart, professor of artificial intelligence. She said: “It is a privilege to be involved in the creation of this system, which will select the best contractor for each job based on their skill set, availability and location and be reactive to changing priorities of jobs." TL, based in Fenstanton, just outside Cambridge, provides asbestos consultancy, project management and training to businesses, local authorities, social housing and education facilities, using a fleet of mobile engineers across the UK. John Richards, managing director at Thames Laboratories, said: “This partnership will allow us to adopt the latest research and expertise from a world-leading academic institute to develop an original solution to improving the efficiency of social housing repairs, maintenance and improvements to better meet the needs of social housing residents.” Professor Ekart will be joined by Dr Alina Patelli as academic supervisor. Dr Patelli brings experience of software development in the commercial sector as well as expertise in applying optimisation techniques with focus on urban systems. She said: “This is a great opportunity to enhance state-of-the-art optimisation and machine learning in order to fit the needs of the commercial sector and deliver meaningful impact to Thames Laboratories.”
• Leading scientist wins €2.2 million ERC Advanced Grant • The five-year project will explore early dementia interventions through understanding how an aquaporin water channel regulates glymphatic clearance • ERC Advanced Grant funding is amongst the most prestigious and competitive of the EU funding schemes. A world leading scientist in the College of Health and Life Sciences at Aston University has been awarded a €2.2 million ERC Advanced Grant to understand how the movement of a protein known as aquaporin-4 in the brain can help slow cognitive decline. The FORTIFY project, which will run for five years, is led by Professor Roslyn Bill in the School of Biosciences. She will apply her discovery of the movement of aquaporin-4 to understand how the cleaning mechanism in the brain works during sleep. The research will focus on how aquaporin-4 controls the glymphatic system, which is the mechanism that allows us to clear waste products from our brains while we sleep. Her hypothesis is that the movement of aquaporin-4 in the brain changes the effectiveness of this cleansing mechanism - which lessens as people age. A greater understanding of this process could lead to an early intervention treatment that could slow the onset of dementia, such as Alzheimer’s and Parkinson’s Diseases. ERC Advanced Grant funding is amongst the most prestigious and competitive of the EU funding schemes, providing researchers with the opportunity to pursue ambitious, curiosity-driven projects that could lead to major scientific breakthroughs. Professor Bill said: “Every three seconds someone in the world develops dementia and there is no cure. I want to stop that from happening. By understanding the molecular mechanisms of brain waste clearance, we have an opportunity to develop medicines that can slow the onset of dementia, very much in the same way that statins are prescribed to control heart disease”. Roslyn Bill discovered that the water channel protein aquaporin-4 increases the permeability of brain cells to water after a brain or spinal cord injury. Around 60 million people a year suffer such injuries following falls or accidents. For example, after a skiing accident in the French Alps in 2013, Michael Schumacher suffered a severe head injury. He was placed in a medically induced coma and underwent several surgeries to treat his injuries. Until now doctors have only been able to manage the symptoms of brain injury (swelling on the brain) through interventions that may require surgery. Professor Bill and her team are due to start clinical trials in summer 2023, to test a method to stop the swelling from happening in its tracks, building on her discoveries. Roslyn’s new ERC-funded project, FORTIFY, will focus on how aquaporin-4 controls fluid flow in the healthy, uninjured brain. In this round of Advanced Grants, the European Research Council (ERC) is awarding €544 million to 218 outstanding research leaders across Europe, as part of the Horizon Europe programme. The grants will support cutting edge research in a wide range of fields, from medicine and physics to social sciences and humanities. The grant is awarded to established, leading researchers with a proven track-record of significant research achievements over the past decade. The funding will enable the researchers to explore their most innovative and ambitious ideas. Mariya Gabriel, European Commissioner for Innovation, Research, Culture, Education and Youth, said: “ERC grants are a top recognition and a significant commitment from our best researchers. The €544 million funding puts our 218 research leaders, together with their teams of postdoctoral fellows, PhD students and research staff, in pole position to push back the boundaries of our knowledge, break new ground and build foundations for future growth and prosperity in Europe” Maria Leptin, ERC President, added: "These new ERC Advanced Grantees are a testament to the outstanding quality of research carried out across Europe. I am especially pleased to see such a high number of female researchers in this competition and that they are increasingly successful in securing funding. “We look forward to seeing the results of the new projects in the years to come, with many likely to lead to breakthroughs and new advances.”
ChristianaCare Will Open Neighborhood Hospital at Its West Grove Campus
Plans for emergency and inpatient care follow extensive planning and community listening sessions ChristianaCare today provided new details about its plans to restore needed health care services to the southern Chester County, Pennsylvania, community at its West Grove campus, formerly Jennersville Hospital. ChristianaCare will open a neighborhood hospital that includes 10 emergency department beds and 10 inpatient beds. The neighborhood hospital will offer emergency care and behavioral health emergency care and provide diagnostic capabilities including ultrasound, computed tomography (CT), X-ray and laboratory services. The emergency department will treat common emergency care needs such as falls, injuries, heart attacks and strokes. Additionally, the hospital will benefit from access to ChristianaCare’s large network of specialists and support services — such as neurology and cardiology — through virtual consults. “We are excited to share our plans to restore important local health care resources to the southern Chester County community,” said Janice Nevin, M.D., MPH, ChristianaCare president and CEO. “We are committed to our neighbors in southern Chester County for the long-term, serving them as expert, caring partners in their health.” ChristianaCare’s plans for a neighborhood hospital meet the Pennsylvania Department of Health’s requirements for a micro-hospital, which must have a minimum of 10 inpatient beds and 10 emergency department treatment rooms and offer imaging services on-site. “After listening to the needs of the community and an extensive review of historical and projected demographic data, we believe this neighborhood hospital model will provide the right mix of health care services for the West Grove campus in a way that is sustainable and meets the community’s most immediate needs today,” said Heather Farley, M.D., chief wellness officer for ChristianaCare and the clinical leader for the West Grove planning. “It also sets us up to grow in meeting more of the community’s needs in the future.” ChristianaCare anticipates an opening date in late 2024, although the date is subject to change due to the significant work that will be required to renovate the facility to bring it up to current standards, including the build-out of an entirely new information technology infrastructure. Last year, ChristianaCare received funding from Chester County and the Commonwealth of Pennsylvania totaling $5 million to assist in facility upgrades. ChristianaCare already serves residents of southern Chester County. Since 2020, ChristianaCare has provided primary care in three practices that are located in Jennersville, West Grove and Kennett Square. The West Grove practice has recently brought on additional providers and will soon begin offering virtual visits with ChristianaCare specialists. Combined, these three practices are now the “medical home” for 22,000 residents in these communities. ChristianaCare finalized the purchase of its West Grove campus from Tower Health in June 2022. The hospital has been closed since Dec. 31, 2021.
MEDIA RELEASE: CAA Worst Roads Campaign marks 20 Years of Driving Change in Ontario
The annual CAA Worst Roads advocacy campaign is marking its 20th year of influencing change. For the past two decades, the campaign has given decision-makers a snapshot of the roads that the public perceives as not meeting their expectations. “Our research tells us that 85 per cent of Ontarians are concerned about the state of our roads,” says Teresa Di Felice, assistant vice president of government and community relations, CAA SCO. “Due to inflation, consumers are being more mindful of their purchases, and people are opting to hold on to their cars for longer instead of buying a new one. Funding for roadway improvements and proper infrastructure needs to be consistent to ensure that quality and safety are maintained.” CAA’s research also indicates that over half of CAA members (59 per cent) say Ontario’s roads have worsened. Drivers often alter their driving behaviour to accommodate road issues. Many of them – two-thirds (66 per cent) of Ontarians – are slowing down for bad spots on the road or swerving to avoid potholes. We also know that many people are frustrated with Ontario's roads (78 per cent) and often express their dissatisfaction to their loved ones or colleagues instead of government officials. The CAA Worst Roads campaign allows all road users in Ontario to vote for roads that they think need urgent repair. Since 2003, 114 roads in Ontario have appeared on the provincial Top 10 list, of which governments have prioritized some of the roads for repair. In 2022, Barton Street East in Hamilton, Ontario, secured the top spot on the provincial Worst Roads list. Shortly after the 2022 Worst Road reveal, the City of Hamilton announced a multi-year, multi-phase reconstruction of the beleaguered Hamilton route scheduled to begin late last year. Other roads, such as Plank Road in Sarnia, Victoria Road in Prince Edward County, Lauzon Parkway in Windsor, and Bell Farm Road in Barrie, have also undergone significant repairs after appearing on the provincial Top 10 Worst Roads list. “The campaign has demonstrated that decision-makers are paying attention to the results, which has prompted municipal officials to move up infrastructure projects in their communities,” says Di Felice. The CAA Worst Roads campaign calls on all Ontarians to vote for their Worst Road today and join the community of drivers, cyclists, and pedestrians committed to improving Ontario’s roads. Ontarians can vote for their worst road at caaworstroads.com. Watch Teresa Di Felice, Assistant Vice President, Government and Community Relations for CAA SCO answers questions regarding the annual CAA Worst Roads Campaign: https://vimeo.com/user140657252/caawrl2023
Expert Q&A: The Summer of Sargassum?
A 5,000-mile-wide mass of sargassum seaweed is drifting toward Florida's beaches. It could arrive, with its brown, slick leaves and rotten eggs smell, around July as the state's Atlantic beaches are filled with locals and tourists. Florida Tech oceanographer Kevin Johnson offered his insights into this looming arrival. Is it dangerous? Will it spoil the beaches? Here are his answers to some key questions. QUESTION: Is this situation really a big deal? Kevin Johnson: I wouldn’t say it is being overhyped, but it is yet to be determined whether this year will have greater amounts of sargassum in the Atlantic offshore, (visible by satellite) or coming ashore and covering the beaches, a connected but separate phenomenon requiring the cooperation of onshore winds. 2018 was a record-setting year, and this year could exceed what was seen in both locations in 2018. If the winds contribute strongly to sargassum coming ashore, it could make it smelly and hard to find an area of clean sand to set up on the beaches. QUESTION: Is there a health risk if we head to a beach where sargassum is present? Kevin Johnson: Sargassum doesn’t produce aerosolized organic toxins, but as it rots on the beach, it will smell and give off hydrogen sulfide gas, or H2S. That's the stuff that smells like rotten eggs. When concentrated in enclosed areas, this gas is toxic and can be harmful. However, in the open air, diluted on an exposed beach, it is more of a smelly nuisance than a genuine health hazard for most people. But there could be a minor irritation, like itching, after coming into contact with sargassum. There are symbiotic species living in and amongst this seaweed when it is healthy and floating at sea. (These intricate relationships are part of what makes sargassum ecologically significant as a food source, nursery and habitat for many populations.) One of the symbionts is a tiny branching colonial hydroid, related to corals. it grows on sargassum fronds. Hydroid colonies have a sting like corals and jellyfish, but it is generally not severe. Some people may experience itching around their feet or ankles (or any body part that contacts the sargassum hydroids) if they brush up against sargassum in waves or swash, or step on freshly deposited sargassum on the sand. Many people will not be bothered or only mildly troubled by this, but some people may be more sensitive to the hydroids. QUESTION: I was planning to visit the beach. Should I reconsider now? Kevin Johnson: If the winds collude with the large bloom already underway to deliver huge mats to the beach, it could be hard for beachgoers to find a place to sit on the sand, and the smells could make the beach untenable. I emphasize “could” with the hydrogen sulfide smell because it depends on how the sargassum is deposited and how wet it is as it breaks down. In some cases, beached Sargassum can be very dry and in such cases it may not smell too bad. People who are more sensitive to the hydrogen sulfide or to the hydroids on the fresh sargassum may find the experience even more unpleasant. Westerly winds would be helpful from the perspective of keeping sargassum away from beaches, but unfortunately easterlies are pretty common this time of year. If you're a reporter looking to know more about this topic, let us help with your coverage. Dr. Johnson can be available for phone, Zoom or, depending on scheduling, in-person interviews.
Is America's banking system in trouble once again?
Nerves are rattled and many are worried as the markets opened Monday to news of another US bank collapse, making that two large banks shuttered in less than a week. It's news that's rocking the financial world on a massive scale. Federal regulators announced on Sunday that another bank had been closed and that the government would ensure that all depositors of Silicon Valley Bank — which failed Friday — would be paid back in full as Washington rushed to keep fallout from the collapse of the large institution from sweeping through the financial system. The Federal Reserve, Treasury and Federal Deposit Insurance Corporation announced in a joint statement that “depositors will have access to all of their money starting Monday, March 13.” In an attempt to assuage concerns about who would bear the costs, the agencies said that “no losses associated with the resolution of Silicon Valley Bank will be borne by the taxpayer.” March 12 - New York Times With an economy already on edge as Americans feel the grip of inflation and worries of recession - this is frightening news and media are scrambling for answers. What is causing the closures of these big banks and how many more will follow? How much money is lost and how much has been protected? Is this 2008 all over again? Is the federal government doing enough to stop the damage from spreading? What measures need to be put in place by government to assure citizens that their savings, retirement plans and mortgages aren't at risk? And will anyone be held accountable for the billions already lost? There's a lot to explain - and that's where our experts can help. Rebel Cole, Ph.D., a Lynn Eminent Scholar Chaired Professor of Finance, has expertise in global financial institutions, commercial banking and small business finance. He spent 10 years working in the Federal Reserve System and has experience at the the International Monetary Fund and the World Bank. Cole has been interviewed by numerous national media outlets, such as The Wall Street Journal, The New York Times, The Washington Post and Fox Business. Rebel is available to speak to media regarding the current state of banking and what Americans need to watch for or worry about. Simply click on his icon now to arrange an interview today.
How Colorism Impacts Professional Achievement
Melissa J. Williams is associate professor of organization and management at Emory University’s Goizueta Business School. She investigates what happens when social identities collide with workplace hierarchies, and the consequences of putting people in positions of power and leadership. Here she looks at something less documented: the extent to which our appearance is stereotypically Black or white. And what that means for our prospects. Rosa Parks made history on December 1, 1955, when she refused to relinquish her bus seat to a white passenger. Her simple gesture of defiance ignited a city-wide bus boycott in Montgomery, Alabama, and has gone down in the annals as a pivotal moment for the social justice movement in the United States. However, Parks was not the only African American to make a stand against racial segregation. Nor was she the first. In March of the same year in the same city, 15-year-old Claudette Colvin also refused to give up her seat to a white woman on a Montgomery bus. So why isn’t she a household name? In part, Colvin’s age was a factor. The National Association for the Advancement of Colored People and other Black civil rights groups got behind Parks, reasoning that an older woman would be better equipped to withstand the controversy. But as Colvin herself stated, there were other factors at play. There was something about Parks’ appearance that gave her more leverage, reasons Colvin explained in Philip Hoose’s award-winning book on the civil rights movement. She had the “right hair and the right look.” Not only that, but her appearance “was the kind that people associate with the middle class. She fit that profile.” Success isn’t black or white. It’s shades of…white. Colorism has long been documented in the U.S. and elsewhere. Discrimination against human beings on the basis of their facial features, hair, and skin color transcends race—it is prevalent even within groups that share the same ethnic identity, where lighter skin tones are perceived to be more valuable than dark. Research over the years has shed light on the nefarious effects of colorism or shadeism in terms of equity and access to opportunity. But a new landmark study by Associate Professor of Organization & Management Melissa Williams, and Goizueta colleagues, PhD student Tosen Nwadei and Roberto C. Goizueta Chair of Organization & Management Anand Swaminathan, looks at just how Black or white someone appears—and how this shapes the way others see their potential; as well as the kinds of professional outcomes they can expect. What Williams and her co-authors, who also include James B. Wade from George Washington University and C. Keith Harrison and Scott Bukstein of University of Central Florida, find in their studies, is that Black professionals are less likely to be promoted to leadership roles. What’s more, for Black professionals whose physical appearance is more Black-stereotypical, their chances drop from 12 percent to a mere seven percent. For white professionals, on the other hand, having a more white-stereotypical appearance is an advantage for leadership – looking more stereotypical as a white person increased their chances of holding a leadership role from 32 percent to 43 percent. Williams and colleagues ran both an archival study and a lab experiment with volunteers to discover the extent to which degrees of ethnicity in appearance influence perceptions of a person’s potential for leadership and actually predict their likelihood of success in an industry. While the science unequivocally shows that white people enjoy advantages over Black people in opportunity and outcome across the board, Williams et al. were also interested in exploring what she calls the “continuum of race:” the more nuanced racial characteristics and differences that shape how the world sees us. There’s an assumption that everyone within the same ethnic group—Black or white—will experience the same degree of bias and prejudice, or acceptance and success. And we wanted to push back on that idea to really explore how degrees of whiteness or Blackness play out in people’s minds and shape how they read you physically. -Associate Professor of Organization & Management Melissa Williams Previous research shows the link between persisting in STEM-based majors in college and how much students are perceived to look “like their race,” she says. Those who are perceived to look less typically Black tend to make more friends outside their ethnic group—a boundary-crossing behavior that can help drive careers. To test these ideas, Williams and co-authors ran two studies. First, they accessed publicly available data including photographs, professional background, and positions from one large industry within the U.S.: American college football. College football is really rich in data. You can access job titles, photos, leadership, and non-leadership roles; and you can separate individuals out into head coaches and position coaches who have overseeing roles but who are not leaders per se. Separately, Williams et al. recruited a group of volunteers to look at the images of the football coaches: a mix of Black and white head and position coaches. These volunteers were asked to rate how typical they perceived each individual’s appearance to be of European or white Americans, or of Black Americans, ascribing each person a score out of five based on features such as their skin color, hair, eyes, nose, cheeks, and lips. These scores were then regressed—or cross-referenced—with the position held by the individuals in the photos to determine the relationship between their racial stereotypicality and their leadership role. Crunching the numbers, Williams found a direct correlation between the degree of perceived whiteness or Blackness of the coaches and how likely they actually were to be successful leaders. “We do find a kind of consensus in people’s view of what it means to be Black or white straight off,” says Williams. “So we do all seem to agree on the physical attributes of race. But it gets really interesting when you regress the scores that these photos get and compare them with the actual jobs these guys hold.” What we see is that, controlling for their age, attractiveness, and professional experience, the white guys who look less stereotypically white are 32 percent likely to occupy leadership roles. This rises to 43 percent with the men who look more like a stereotypical white guy. For Black professionals, the inverse is true, she notes. The more typically Black an individual looks, the less probability there is that he occupies a leadership job. Specifically, that figure drops from 12 to seven percent. So benchmark leadership probability is not only already lower for Black individuals, but drops even further when people are deemed to look “more typically Black,” says Williams. A follow-up experiment invited volunteer football fans to compare how they saw the potential future success of two same-race college football players—one more stereotypical in appearance than the other. The results confirm what Williams et al. suspect: 70 percent of the time, participants chose the more-typical white individual over the less-typical white individual as having greater leadership potential. In other words, the more white a white person looks, the more they are seen as leadership material. These findings should translate into an imperative, says Williams; and that is to think more broadly about race and how it impacts life outcomes. Because race is not a uniform experience, she says. “Organizations might want to look beyond just ticking the box when it comes to diversity and inclusion, and give deeper thought to who they want to recruit, support and push forward in representation. For white people, paying attention to whiteness—the types of white people who enjoy advantages in leadership—can be useful in reframing certain questions. A good place to start might be for leaders to ask: do I want to support people who look like me? Because the face you choose can ultimately help disrupt, or reinforce, the stereotype.” Interested in learning more or connecting with Melissa J. Williams, associate professor of organization and management at Emory University’s Goizueta Business School? She's available to speak about this subject - Simply click on her icon now to arrange an interview today.
Protein engineer to explore route from DNA blueprint to synthetic antibodies – public lecture
Professor Anna Hine will explore how advances in protein engineering have enabled us to make both synthetic antibodies and their replacements Inaugural lecture will take place at Aston University on Tuesday 28 March 2023 at 6.30pm Members of the public may attend in person or online. Professor Anna Hine, a molecular biologist specialising in protein engineering in the College of Health and Life Sciences at Aston University, is to present her inaugural public lecture on Tuesday 28 March 2023. During her lecture, A route to synthetic antibodies (and their replacements), Professor Hine will take the audience from the basics of molecular biology to explaining her inventions in protein engineering, through to examining the ways in which her research is being applied internationally to develop synthetic antibodies. Professor Hine gained her PhD in molecular biology from The University of Manchester Institute of Science and Technology in 1992 and did her postdoctoral training at Harvard Medical School. She returned to the UK to take up a lectureship in molecular biology at Aston University in 1995. Professor Anna Hine, professor of protein engineering, said: “Antibodies are one of our major lines of defence against infection and we can create them very quickly to help incapacitate a multitude of biological invaders. Humans do this by changing the part of the antibody that recognises the invading pathogen, through a process of rapid, natural mutation. Protein engineers have learned to mimic this process in the laboratory to create synthetic proteins – particularly antibodies - for use in both therapy and fundamental research.” “I am delighted to have the opportunity to present our discoveries in a way that I hope will make just as much sense to non-scientists as to a scientific audience.” Similar to the natural mutation of antibodies, protein engineers can make vast numbers of tiny variations of a protein such as an antibody. Professor Hine added: “We will contemplate the vast numbers involved in protein engineering and present how our Aston University-based inventions have made the creation of DNA (and thus protein) ‘libraries’ as efficient as possible. “We will then examine the ensuing problem of how to find the few proteins that we really want from within a protein library. This includes collaborating with experts who specialise in computer-assisted library design and also working with those who have developed the latest methods to search the libraries that we make.” Professor Hine will also show how her latest collaborative projects are starting to move beyond the antibody itself. The lecture will take place at Aston University at 6.00pm for 6.30pm on Tuesday 28 March 2023. It will be followed by a drinks reception from 7.30 pm to 8.00 pm. The lecture is open to the public and free to attend. Places must be booked in advance via Eventbrite.
• Institute of Health and Neurodevelopment to host children’s activities at Birmingham’s science museum Thinktank on Saturday 18 March • British Science Week is a ten-day celebration of science, technology, engineering and maths • Brain Awareness Week highlighted with research showcased in glass box exhibition space on University campus. Aston Institute of Health and Neurodevelopment (IHN) is celebrating British Science Week (10-19 March) and Brain Awareness Week (13-19 March) by hosting an activities day for children at the Birmingham science museum Thinktank, alongside a social media campaign to help educate and inform the public on its latest research. Each year, the British Science Association runs a ten-day celebration of science, technology, engineering and maths called British Science Week. It is closely followed by Brain Awareness Week, a yearly global campaign to increase public awareness of brain research. The week-long celebration is organised by the Dana Alliance with a goal to educate and highlight the importance of research in developing new treatments, preventions and possible cures for brain diseases. Both campaigns align closely with the work of the Aston Institute of Health and Neurodevelopment, with the Institute’s researchers keen to use the week to host activities and share their research and information about the brain health with the public. Activities to highlight both British Science Week and Brain Awareness week include a social media campaign sharing research updates from members and surprising brain facts on Twitter (@Aston_IHN), a brain research exhibition in the glass box space in the Aston University main entrance, as well as an activity session at the Birmingham science museum Thinktank in Millennium Point. The meet and greet with IHN researchers will take place on Saturday 18 March between 11.00 and 16.00. Children and families can speak to researchers about their work and take part in interactive activities, such as memory games and eye-tracking experiments. Professor Jackie Blissett, co-director of IHN said: “British Science week and Brain Awareness week are really important campaigns for us. Brain Awareness week is the perfect time to showcase our research and engage with the public on what we do here at IHN. “We work in close collaboration with the NHS to help research potential treatments for children who experience a range of brain related conditions. We put children at the heart of what we do, with the aim of unlocking the potential of research to support children’s health and development as well as answering the questions that matter to children, their families and the services that support them.” Visitors to the exhibition on the Aston University campus are encouraged to share their thoughts about the exhibition and their pictures on Twitter, tagging @Aston_IHN. For more information about Aston Institute of Health and Neurodevelopment visit its website and for more information about studying psychology and neuroscience at Aston University visit our course pages.
