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EY Government and Public Sector Cyber Security team and the Cyber Security Innovation (CSI) Centre at Aston University won £180,000 in funding from the Department for Digital, Culture, Media and Sport Experts will work with the UK Government to find appropriate opportunities for investment in cyber security The research will map blind spots within the UK’s regional security innovation systems. Cyber security experts at Aston University will work with the Government to support its national cyber security strategy by mapping blind spots in the UK’s regional cyber security systems. The Cyber Security Innovation (CSI) Centre at Aston University will work with EY Cyber Security Consulting on the £180,000 project for the Department for Digital, Culture, Media and Sport (DCMS) to research and map the UK cyber security ecosystem. The project will consider the current environment, conditions and interventions that exist to influence or affect companies providing cyber security products, services or solutions to support and contribute to the development and growth of cyber security businesses in the UK. The aims of this research are to provide the DCMS with robust evidence of a region-by-region picture of where public, private, academic and industry support mechanisms are in place and to identify service and geographical gaps in their provision. It comes after the CSI Centre helped launch the UK government’s National Cyber Strategy 2022 in Birmingham at a special event last December, for which Aston University professor of cybersecurity management, Vladlena Benson, was an instrumental member of the organising committee. The current project will enable the strategy implementation to support the UK Government’s ambition to grow innovation and academic research in cyber. Dr Anitha Chinnaswamy, lecturer in cyber security management at the CSI Centre at Aston Business School, says: “From the datasets collected that includes different cyber security businesses, incubators, accelerators, clusters, academic centres of excellence and other different mechanisms from across the UK, analysis will be conducted to provide a region-by-region basis of practices involved. “The mapping of the cyber security landscape will also enable the enhancement of skills and diversity across the cyber security sector. “The diversity in cyber security market lags other digital sectors, with the cyber workforce consisting of only 15% females, 16% ethnic minority backgrounds and 9% neurodivergent. The results of this project will be an important contribution for the government to foster the growth of a sustainable, innovative, and internationally competitive cyber and information security sector.”
As he arrived at ChristianaCare’s emergency department because of diabetes complications that were causing excruciating pain in his left foot, Edwin Bryson Sr., 71, of Wilmington, Del., had resigned himself to what seemed inevitable—he was going to need hospitalization. But he was surprised when his care team offered him the chance to get the hospital care he needed in the place he likes best — his own apartment. For 20 days, Bryson was a patient in the ChristianaCare hospital care at home program, which offers in-home services to patients who would otherwise require inpatient hospitalization. Daily, members of his care team visited his home to take his vital signs, give him medication and assist him with getting dressed. They also helped with additional tasks to improve his overall health and safety, such as buying an extra lamp and flashlights to ensure the lighting in his home was adequate for his safety, and assisting him with ordering food. “It was a good feeling to be at home,” Bryson said. “My friends would knock on my door and make sure I was OK. My son and my nephews could stop to see me when they felt like it or had the time. They always say, ‘There’s no place like home,’ and it’s true. All I do is hit the button and a nurse comes on to assist me with anything I need and check on my vitals. It was 24-hour service here, just like I was in the hospital.” ChristianaCare has admitted and cared for more than a dozen patients in the hospital care at home program since it launched in December 2021, designed in partnership with the Medically Home Group Inc. The program, which offers the highest level of in-home acute care in Delaware, combines virtual and in-person care provided by a team of physicians, nurse practitioners, registered nurses and other providers. In-person and virtual visits from the health care team, along with mobile imaging and lab services, delivery services for meals and nutrition, and pharmacy medication and management, mean a patient doesn’t need to leave home to get better. Virtual technology and home health equipment brought into the patient’s home ensure round-the-clock monitoring and care that mirrors a traditional hospital setting. “One of the things we’ve learned in a short time about the hospital care at home program is how patient-centered this approach is and how we’re able to customize the care we deliver,” said Sarah Schenck, M.D., medical director of the program. “Most of the things we can do in the hospital we can also do at home. And it turns out patients really prefer that venue. They’re in their own home with their loved ones, their pets, sleeping in their own bed and eating their own food.” Currently, to be considered for hospital care at home, patients must live within 25 miles of Christiana and Wilmington hospitals. Patients who come to the emergency department with common chronic conditions such as congestive heart failure, respiratory ailments, diabetes complications and infections like pneumonia, are eligible for consideration. All hospital care at home patients receive a technology kit that connects them to the command center, powered by the ChristianaCare Center for Virtual Health. With a touch of a button, patients can access an expert team of ChristianaCare physicians and nurses. When patients are well enough to be discharged, the care team collaborates with the patient’s primary care physician to ensure a seamless transition. ChristianaCare joins an elite group of health systems nationwide offering at-home hospital care. Clinical research studies comparing patients in traditional hospitals with patients who received hospital-level care at home have found those who received in-home care experienced fewer readmissions, lower mortality rates, reduced falls and lower costs. “Patient satisfaction is really high with this program,” said Steaphine Taggart, director of operations for the program. “There’s more caregiver interaction with families because they are allowed to come into the home. And overall, there’s more patient-centered care and delivery because it’s in the home,” Registered nurse Mary Pat McCabe has treated patients for 17 years. Working in the hospital care at home command center, she has the opportunity to be even more personable in the virtual setting than a traditional inpatient encounter. “You get to know them and their family members and if they have a pet. You can see into their home and get more of a feel for who they are,” McCabe said. Dr. Schenck said hospital care at home is an exciting example of how new, innovative models of care can improve patient outcomes, reduce costs and transform care. “It’s really foundational for the future of health care delivery. This is our first step, but it’s definitely going to grow,” she said. For Bryson, who was recently discharged, it’s even simpler: “You get better, get back out there and get back into life again.”
Aston University appoints new Vice-Chancellor
Aston University is delighted to announce that Professor Aleks Subic has been appointed as its next Vice-Chancellor and Chief Executive. He succeeds Professor Alec Cameron, who stepped down after five years in December 2021. He will take up the post in August 2022, until which time Saskia Loer Hansen will continue in her role as Interim Vice-Chancellor. Dame Yve Buckland, Pro-Chancellor of Aston University, said “I am absolutely delighted at Professor Aleks Subic’s appointment. He joins the University at an exciting time and his wide experience of leadership across both academia and industry makes him a perfect fit for Aston University’s needs and ambitions.” Professor Subic said “I feel privileged at being given the opportunity to lead Aston University at this time. The University is renowned for its commitment to graduate employability, translational research and its engagement with business. “I look forward to continuing the momentum built up by Professor Alec Cameron and Saskia Loer Hansen, and I am ambitious to see Aston University continue to build on its reputation for high quality teaching, research and business engagement locally, nationally and internationally.” Saskia Loer Hansen, Interim Vice-Chancellor of Aston University, said “I should like to congratulate Professor Subic warmly on his appointment. His credentials as a leader, both in industry and in higher education, equip him for guiding Aston University to even greater success. “I am sure he will work rigorously to build on our achievements, promote the University worldwide and further strengthen our reputation as a leading university for business and enterprise.” Professor Subic is currently the Deputy Vice-Chancellor (STEM) and Vice President (Digital Innovation) at RMIT University, where he is responsible for leading the STEM College and Digital Innovation portfolio in Australia and globally. Prior to this appointment he was the Deputy Vice-Chancellor (Research & Enterprise) at Swinburne University of Technology, responsible for research, graduate studies, engagement and partnerships, advancement, innovation, enterprise, and commercialisation, leading the research transformation of the university towards top 2% in the world. Before that, he was the Executive Dean of Engineering at RMIT University, one of the largest engineering faculties in Australia, ranked in top 1% in the world and renowned for industry-partnered education and research. Concurrent with his academic appointments, Professor Subic has held notable appointments on the Australian Prime Minister's Industry 4.0 Taskforce and the Australian Advanced Manufacturing Council Leaders Group (Australian Industry Group). Previously he was the Director and Deputy Chair of the Australian Association of Aviation and Aerospace Industries, Director of Oceania Cybersecurity Centre Governing Board, Director of the Society of Automotive Engineers Australasia Board, Director of National Imaging Facility Governing Board, Director of Australian Housing and Urban Research Institute Governing Board, and Director of the Victorian Centre for New Energy Technologies Governing Board. He has served on a number of national and international research committees and expert panels, including as Chair of the European Research Council Expert Panel for Physical Sciences and Engineering, Technology Group of the Global Federation of Competitiveness Councils, Forbes Technology Council, Defence Materials Technology Centre, Editor and Associate Editor of international scholarly journals.
Will voters 'hit' or 'hold' on allowing legal gambling in Georgia?
Could we see horse racing and other forms of gambling come to Georgia in the near future? The Georgia state legislature is looking at the possibility of legalizing gambling on horse racing and the decision could land in the hands of the voters. Proponents say there is potential for a billion dollars in economic benefits, from job creation to a boost in revenues. Marsha Loda is an associate professor at Augusta University’s Hull College of Business. She said if approved, it will likely take more than horse racing for a track to survive. Loda cites Kentucky as an example of what tracks are doing there. “A lot of people think of Kentucky as the mecca of horse racing, but they don’t realize it might not exist without historical horse racing machines," said Loda. "HHRs are slot-like machines that let players wager on past horse races by a random number generator.” Many tracks nationwide have also expanded into casino and sports betting. While this isn’t what Georgia is looking to do initially, it’s not far off to think it could be on the horizon, with horse racing being the first step. Loda, who previously served as marketing director at Harrah’s Cherokee Resort in North Carolina, knows if casino gambling is approved in the future, most of those people who visit need to come from out of town. “You need to be able to import your people who are going to bet. That means you’re importing revenue. Otherwise you’re taking what’s already spent in your community and just slicing it up and giving it to different places. You’re not growing the pie at all,” said Loda. She has also seen the benefits of legalized betting, citing the added jobs a casino would offer. One aspect of gambling that has exploded is sports betting. More than two dozen states have legalized sports betting. Loda thinks if sports betting was on a ballot and went in front of the public for a vote, it would stand a better chance of passing. “I wouldn’t be surprised to see Georgia pass sports betting. I think sports betting has been very well accepted. I think they would come much closer to getting more voters to approve it if it were sports betting than if it’s horse racing or casino gambling.” This is an important topic with many angles to cover, and if you are a reporter looking to know more, then let our experts help. Loda is a leading marketing expert helping businesses in the hospitality industry bounce back from crises, including the COVID-19 pandemic, and also has had extensive experience in the gambling industry. She is available to speak with media regarding the idea of gambling coming to Georgia. Simply click on her icon now to arrange an interview today.
10 resume mistakes to avoid when applying for jobs in Canada
As a newcomer to Canada, applying for your first job can be stressful. The recruitment process may be different from what you’ve experienced back home and it can take some time to understand what will make your application stand out in Canada’s competitive job market. As you look for your first job in Canada, your resume will likely be key in determining whether or not you get the role. In Canada, most companies run the resumes they receive through a resume-scanning software to filter ones that best match the requirements laid out in the job description. If you’re shortlisted, your resume and cover letter will be sent to a recruiter or hiring manager, and they’ll decide whether you’re an ideal candidate for the position. Since your resume will determine the first impression you make on the hiring manager, there’s a lot riding on what you include––or not. Should you really submit that extra page? (Maybe.) Is it okay to exaggerate your credentials? (No!) What about using a fun font? (Better not to.) Here are 10 common resume mistakes newcomers tend to make and guidance on how to avoid them. 1. Using the same resume for different job applications Landing your first job in Canada can take a few months and it’s easy to get overwhelmed and exhausted by the process. When you’re applying to hundreds of job positions, the idea of using the same generic resume for multiple positions can be tempting. However, customizing your resume significantly improves your chances of being selected. Every job is unique––and your application should be too. While your applicant profile won’t vary significantly from one application to the next, the way in which you present it should be customized for each company and job opening. A good way to do this is to look for keywords in each job posting and sprinkle them throughout your resume where they make sense. This will help your resume get past both the resume-scanning software and human recruiters tasked with reading dozens, if not hundreds of applications. Be sure to include experience and behavioural traits mentioned in the job posting. (For example, if the ideal candidate is proficient with a certain type of software, you should definitely mention any experience you have with it.) At the same time, remove experiences and skills that aren’t a match, so whoever reads your resume isn’t distracted by non-essential items. 2. Not reading the job description before creating your resume Reading the job description will give you vital information about the role and the potential candidate an organization is looking for, including key skills and experiences. Not only will this information help you determine if you’re a good candidate, it’ll also help you craft the perfect resume. Many Canadian employers use applicant tracking systems (ATS) to screen resumes and shortlist ones that match the job description. This means it’s essential your application takes the job ad into consideration. As mentioned above, you’ll want to look for keywords and descriptions you can include in your cover letter and resume. It’s also a good idea to include some synonyms and similar words to these keywords. The idea is to include just enough keywords for your resume to pass the ATS, while ensuring that it reads well for a human recruiter. Only include keywords where it makes sense to do so and don’t include too many in a row. Your cover letter and resume should always be grammatically correct, easy to read, and flow naturally. 3. Listing job responsibilities instead of achievements Unlike some countries where resumes are supposed to outline your past roles and responsibilities, in Canada resumes focus on achievements. Listing past job responsibilities doesn’t tell future employers how you performed in a role. The goal is to make you stand out from every other applicant with similar job experience, so make sure you emphasize what you brought to a company or team as an individual. The best way to do this is by listing achievements, citing numbers or data that may grab an employer’s attention, or describing challenges you overcame. This isn’t the time to be modest! You want to share what makes you special. 4. Grammatical errors and typos in your resume Proofread, proofread, and proofread again before hitting “send.” Missing grammatical errors and typos is the worst resume mistake you can make and can cost you a job, even if you’re a good candidate for the role. Grammatical errors will make your resume stand out in all the wrong ways, undermining your credibility and bringing into question your attention to detail. If possible, have a friend, family member, or mentor proofread your cover letter and resume as well. This is even more important if English isn’t your first language. You can use spell check as a guide, but don’t rely on it to catch all your errors. 5. Creating a resume that’s too long or too short One of the biggest questions Canadian job seekers have is how long their resume should be. The exact answer depends on the specific job at hand and an applicant’s work experience, but generally resumes should be one to two pages long. A cover letter should be no longer than one page, but not shorter than three to four paragraphs. The more years of work experience you have under your belt, the closer to two pages your resume can be. If you’re fresh out of school or less than a decade into your career, it’s better to stick to one page. As you progress in your career, it’s also normal to cut out early-career work experience and keep educational experience to a single line. A recruiter for a senior-level position doesn’t need to read about your early-20’s internships or time spent in debate club. 6. Not using action verbs You want to use powerful and impactful language in your resume, which means using action verbs. Action verbs are verbs that imply that the subject (you) is doing something. These are a great way to showcase your initiative, rather than passively saying you were “responsible for” something. Good examples of action words to use in a cover letter or resume include “led,” “managed,” “succeeded,” “surpassed,” “created,” and “delivered.” Try to use a mix of action words and avoid repeating the same ones in consecutive points. 7. Including information not typically included in Canadian resumes In Canada, you’re not supposed to include information like your marital status, religion, gender, age, or sexual orientiation in your cover letter or resume. Unless you’re applying for a modelling or acting job, you’re also not supposed to include a photo or headshot. Not only will this extra information take up valuable page space, it could cause a potential employer to avoid your resume for fear of accusations of unintentional or intentional discrimination. It’s actually illegal in Canada for an employer to ask for information like your sexual orientation, age, or ethnicity in a job application process or interview. To avoid putting a recruiter or employer in an awkward situation, it’s best to stay away from these topics. It’s also considered improper to include salary expectations or irrelevant personal hobbies in your application. In Canada, you can skip writing “references available upon request,” as that’s understood and doesn’t need to be stated. 8. Submitting a cluttered or improperly-formatted resume First and foremost, a resume should always be organized and easy to read. An employer should be able to easily pick out your work experience, any volunteer experience, and educational background. Be sure to leave enough white space around text. This typically means 1 or 1.5 line spacing and wider margins. Job applications also aren’t the time to get creative with fonts. Stick to classics like Times New Roman, Arial, or Calibri with a size of at least 10, but not larger than 14. Avoid mixing fonts or using too many different font sizes. Also avoid going overboard with bolding, underlining, or italicizing. If you need more guidance on formatting your resume in the Canadian style, you’ll find the tips and templates you need in our article on Canadian resumes and cover letters. 9. Listing inaccurate contact information It doesn’t matter how great your resume is if a potential employer can’t contact you. If you’ve recently moved or changed your phone number or e-mail address, make sure the information included in your cover letter and resume is up to date. Either way, proofread this information multiple times to avoid typos. It’s also important to make sure your email address is professional (avoid using contact email addresses like cutiepie468@hotmail.com or rockstar732@yahoo.com). Ideally, it should be formatted firstname.lastname or using your initials and not include any nicknames or slang language. 10. Lying on your resume You may be tempted to exaggerate your experience or accomplishments, but this is a big ethical no-no and a dealbreaker for any potential employer. Many Canadian recruiters and employers will verify your credentials and background through other sources, whether that’s by calling references, conducting background checks, or looking you up on LinkedIn or other social media platforms. If you lie, you’re very likely to get caught. If you’re worried about an employment gap, it’s better to plan to explain it than cover it up with a lie. As a newcomer, landing a first job can be challenging. However, it’s important to avoid the urge to embellish or lie to make your resume more impressive. Remember, most employment contracts include a clause that allows an employer to terminate your position if they find you lied on your job application. That’s not the type of stress you need hanging over your head! Having a good resume is crucial for your job search. Your resume is essentially your first interaction with a prospective employer and it should convey why you’re an ideal candidate for the job. By avoiding these common mistakes, you can make a positive impression and stand out among a pool of candidates to land a job in Canada. Original article located here, published by Arrive. About Arrive Arrive is powered by RBC Ventures Inc, a subsidiary of Royal Bank of Canada. In collaboration with RBC, Arrive is dedicated to helping newcomers achieve their life, career, and financial goals in Canada. An important part of establishing your financial life in Canada is finding the right partner to invest in your financial success. RBC is the largest bank in Canada* and here to be your partner in all of your financial needs. RBC supports Arrive, and with a 150-year commitment to newcomer success in Canada, RBC goes the extra mile in support and funding to ensure that the Arrive newcomer platform is FREE to all.
Bowel or fecal incontinence, according to the Mayo Clinic, “is the inability to control bowel movements, causing stool (feces) to leak unexpectedly from the rectum. Also called bowel incontinence, fecal incontinence ranges from an occasional leakage of stool while passing gas to a complete loss of bowel control. Common causes of fecal incontinence include diarrhea, constipation, and muscle or nerve damage. The muscle or nerve damage may be associated with aging or with giving birth.” Dr. Satish Rao is a seasoned gastroenterologist and an expert in digestive health, particularly the brain-gut connection. Rao, a professor of medicine at the Medical College of Georgia at Augusta University, recently offered a Q&A on the topic of fecal incontinence with the journal Gastroenterology & Hepatology. What is the prevalence of fecal incontinence in the adult population? Surveys have indicated a prevalence of approximately 9% to 10% in the United States. A recent study reported a 14% prevalence, although this study was Internet-based and, thus, may not have included many elderly patients, as they may not be as computer-savvy as younger patients. It is safe to say that one in seven Americans currently suffers from fecal incontinence. Prevalence appears to be equal in men and women, although women outnumber men almost three to one when it comes to gastroenterology clinic visits and health care-seeking. Men may be too embarrassed to bring the issue of fecal incontinence to the attention of a physician, but when asked about it, they will admit and discuss it. Also, extracting information from a patient about fecal incontinence depends on how the question is asked. Asking patients whether they have daily leakage vs whether they ever have had leakage or have had leakage in the past month will elicit different responses that a clinician may interpret differently. It is important to remember that leakage is not a physiologic event that a healthy adult should have at any time, even once a month or once a year. Not having the capacity to control bowel evacuation or having leakage unaware of its occurrence signals an abnormality. What are notable risk factors for fecal incontinence? In women, pregnancy can be a risk factor, particularly if giving birth involves pelvic tissue damage, such as injury inflicted by forceps use or the unfortunate occurrence of a significant tear. Neurologic or back injuries are other common risk factors. Also, chronic diarrhea can progress to fecal incontinence owing to severe irritation of the rectum or irritants in stool. Further, any condition that changes the ability of rectal capacity can result in fecal incontinence. These circumstances can include surgery or radiation to the rectal area. Hear from a patient and learn more about Rao's research using magnetic stimulation to treat fecal incontinence. What treatment modalities are currently available? Simple, conservative treatment consists of educating patients about fecal incontinence and instructing them to avoid precipitating events. For example, although many people love to have a meal followed by a cup of coffee and a walk, such a sequence of activities is ill-advised for an incontinent patient: the meal provokes a gastric-colonic response, coffee is a powerful colonic stimulant, and exercise also stimulates motility. This triad creates the perfect storm for a stool leakage or accident while the patient is out on the after-dinner walk. Antidiarrheal therapies can be very effective but only in approximately 15% to 20% of patients. Another treatment is biofeedback, which can correct muscle weakness using behavioral techniques. Biofeedback provides resolution in approximately 50% to 70% of patients. The traditional model of office-based biofeedback requires that the patient make 6 or even up to 10 visits to a specialty clinic. This may mean that some patients must drive very long distances to an appropriate care facility that is staffed with trained personnel or physical therapists. This scenario presents a significant challenge for many patients, which is increasingly being recognized by health care professionals and researchers. Good devices for home-based biofeedback have been scarce; however, such a device was recently approved by the US Food and Drug Administration. The research center at Augusta University has tested it in a clinical trial setting and found it to be quite effective as a home biofeedback treatment. Dextranomer is another treatment modality. It involves injection of small beads of dextran polymers into the anorectal region. The beads form a protective cuff or a buffer to stop stool leakage. Another treatment modality is sacral nerve stimulation using the Medtronic InterStim system. The patient is outfitted with a pacemaker-like device with wires that continuously stimulate the sacral nerves that control stool events. In the case of a torn muscle, suturing the torn ends to reduce the size of the anorectal opening is usually useful for women postpartum, although the effect may not be sustained in the long term. What emerging treatments and research should clinicians be aware of? One emerging treatment developed at Augusta University’s Clinical Research Center is called translumbosacral neuromodulation therapy (TNT). TNT is similar to TAMS and involves the fecal delivery of magnetic energy through an insulated coil to the lumbosacral nerves that regulate anorectal function. The pulses generated are of the same strength as those of magnetic resonance imaging. The team at Augusta University’s research center has shown that TNT mechanistically improves nerve function and substantively improves stool leakage. A sham-controlled study and long-term study are currently underway at Augusta University and Harvard University’s Massachusetts General Hospital. These studies are being sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases. A multicenter study sponsored by the National Institutes of Health that the team at Augusta University also is involved with is the FIT (Fecal Incontinence Treatment) trial. This randomized study compares biofeedback with dextranomer injection. Also, as mentioned, tools are becoming available for home biofeedback that should allow many more affected patients to receive treatment because they can do so in the comfort of their own home. The research center at Augusta University is working on a novel home biofeedback protocol for the treatment of constipation and fecal incontinence. Thus, novel noninvasive tools are emerging for fecal incontinence. The repertoire of current and emerging tools holds the promise of improved outcomes for patients with fecal incontinence. Rao is also the founder of the Augusta University Digestive Health Center. He is available to speak to media regarding any aspect of digestive health -- simply click on his icon now to arrange an interview today.
Antimicrobial resistance now causes more deaths than HIV/AIDS and malaria worldwide – new study
Antimicrobial resistance is spreading rapidly worldwide, and has even been likened to the next pandemic – one that many people may not even be aware is happening. A recent paper, published in Lancet, has revealed that antimicrobial resistant infections caused 1.27 millions deaths and were associated with 4.95 million deaths in 2019. This is greater than the number of people who died from HIV/AIDS and malaria that year combined. Antimicobial resistance happens when infection-causing microbes (such as bacteria, viruses or fungi) evolve to become resistant to the drug designed to kill them. This means than an antibiotic will no longer work to treat that infection anymore. The new findings makes it clear that antimicrobial resistance is progressing faster than the previous worst-case scenario estimates – which is of concern for everyone. The simple fact is that we’re running out of antibiotics that work. This could mean everyday bacterial infections become life-threatening again. While antimicrobial resistance has been a problem since penicillin was discovered in 1928, our continued exposure to antibiotics has enabled bacteria and other pathogens to evolve powerful resistance. In some cases, these microbes are resistant even to multiple different drugs. This latest study now shows the current scale of this problem globally – and the harm it’s causing. Global problem The study involved 204 countries around the world, looking at data from 471 million individual patient records. By looking at deaths due to and associated with antimicrobial resistance, the team was then able to estimate the impact antimicrobial resistance had in each country. Antimicrobial resistance was directly responsible for an estimated 1.27 million deaths worldwide and was associated with an estimated 4.95 millions deaths. In comparison, HIV/AIDS and malaria were estimated to have caused 860,000 and 640,000 deaths respectively the same year. The researchers also found that low- and middle-income countries were worst hit by antimicrobial resistance – although higher income countries also face alarmingly high levels. They also found that of the 23 different types of bacteria studied, drug resistance in only six types of bacteria contributed to 3.57 million deaths. The report also shows that 70% of deaths that resulted from antimicrobial resistance were caused by resistance to antibiotics often considered the first line of defence against severe infections. These included beta-lactams and fluoroquinolones, which are commonly prescribed for many infections, such as urinary tract, upper- and lower-respiratory and bone and joint infections. This study highlights a very clear message that global antimicrobial resistance could make everyday bacterial infections untreatable. By some estimates, antimicrobial resistance could cause 10 million deaths per year by 2050. This would overtake cancer as a leading cause of death worldwide. Next pandemic Bacteria can develop antimicrobial resistance in a number of ways. First, bacteria develop antimicrobial resistance naturally. It’s part of the normal push and pull observed throughout the natural world. As we get stronger, bacteria will get stronger too. It’s part of our co-evolution with bacteria – they’re just quicker at evolving than we are, partly because they replicate faster and get more genetic mutations than we do. But the way we use antibiotics can also cause resistance. For example, one common cause is if people fail to complete a course of antibiotics. Although people may feel better a few days after starting antibiotics, not all bacteria are made equal. Some may be slower to be affected by the antibiotic than others. This means that if you stop taking the antibiotic early, the bacteria that were initially able to avoid the effect of the antibiotics will be able to multiply, thus passing their resistance on. Likewise, taking antibiotics unnecessarily can help bacteria to evolve resistance to antibiotics faster. This is why it’s important not to take antibiotics unless they’re prescribed, and to only use them for the infection they’re prescribed for. Resistance can also be spread from person to person. For example, if someone who has antibiotic-resistant bacteria in their nose sneezes or coughs, it may be spread to people nearby. Research also shows that antimicrobial resistance can be spread through the environment, such as in unclean drinking water. The causes driving this global antimicrobial resistance crisis are complex. Everything from how we take antibiotics to environmental pollution with antimicrobial chemicals, use of antibiotics in agriculture and even preservatives in our shampoo and toothpaste are all contributing to resistance. This is why a global, unified effort will be needed to make a difference. Urgent change is needed in many industries to slow the spread of antimicrobial resistance. Of the greatest importance is using the antibiotics we have smarter. Combination therapy could hold the answer to slowing down antimicrobial resistance. This involves using several drugs in combination, rather than one drug on its own – making it more difficult for bacteria to evolve resistance, while still successfully treating an infection. The next pandemic is already here – so further investment in research that looks at how we can stop this problem will be key.
Two glasses of wine might add more sugar to your diet than eating a doughnut
Soft drinks have been the focus of the UK government’s attempts to curb people’s sugar intake in recent years, but the same approach has not yet been applied to the sugar content in alcoholic drinks. The government introduced “sugar taxes” on soft drinks in 2018, meaning manufacturers are charged a levy of up to 24p per litre of drink if it contains eight grams of sugar per 100 millilitres. This was done in order to attempt to reduce the public’s sugar intake in light of increases in childhood obesity. But a new report from Alcohol Health Alliance UK has suggested that just two glasses of wine contains enough sugar to meet the maximum recommended daily intake level – even more than a glazed doughnut. The report found that some bottles of wine contain as much as 59 grams of sugar per bottle. A standard bottle of wine contains 750 millilitres, which is equivalent to three large glasses of wine. This means in some cases a single large glass of wine can contain just under 20 grams of sugar, almost twice the sugar content of that glazed doughnut. So, when it comes to alcoholic drinks, how much sugar do they contain? Consumption of sugar-sweetened drinks has been linked to an increased risk of weight gain and obesity, and associated conditions such as type 2 diabetes. Most research into sugary drinks has focused on soft drinks, such as colas. Alcohol, or ethanol to give it it’s proper name, is itself calorific. Alcohol is second only to fats in terms of its calorie content per gram. On top of this potentially significant calorie content is the sugar that is contained in many alcoholic drinks. This includes the non-fermented starches and sugars found in beers and wines, or sugars added to some drinks such as cocktails or mixers to add flavour. It is unsurprising therefore that alcohol consumption has been associated with weight gain. Sugar levels in cocktails Surveys have reported that alcoholic drinks account for 10% of daily intake of added sugar in the UK for 29 to 64-year-olds, and 6% for the over 65s. This difference may be explained by the alcoholic drinks chosen by these different age groups. Near the top of the list of sugary drinks is likely to be the recent phenomenon of pre-made cocktails in a can, with some containing a staggering 49 grams of sugar per serving. Other more traditional cocktails also fare poorly when scrutinised for sugar content, a summer fruit cup cocktail, for example, may contain more than 25g of sugar per serving. This figure could be higher at home, depending on who makes the drink, and what is considered a serving. Having several of these cocktails won’t just make you merry, but will also provide more sugar than eating several chocolate bars. Wine can vary dramatically in sugar content, with the seemingly healthier lower strength alcohol wines often having more sugar and therefore not necessarily being healthier. In general, dry wines or red wines generally have lower sugar levels. For those of us who enjoy beers and ciders, these drinks can contain even more sugar per serving than wine. A pint of cider, for example, contains more than 25g of sugar, with some ciders containing an eye watering 46g of sugar per serving. Because spirits such as gin, vodka, whisky and rum are highly distilled their sugar content should be negligible. Without mixers, these drinks are clearly the healthiest in terms of both sugar and calorie content. The mixers they come with can however be sugar-sweetened so if you want to avoid sugar, having your gin neat or on the rocks is the best way forward. Better labelling It is clear that more can be done to alert people to the sugar content of alcoholic drinks. The first step would be to mandate that alcohol producers accurately label their products, not just with alcohol content by volume, but also sugar and calorie content, so consumers can make informed choices. Equally, altering the sugar levy to target alcoholic drinks more specifically would likely cause drinks manufacturers to alter their recipes to have less sugar content. The levy on soft drinks has shown this can work, with significant reductions in consumption of sugar-sweetened non-alcoholic drinks since 2018. The government claimed that the tax on soft drinks resulted in more than 50% of manufacturers reducing sugar content in drinks between March 2016, when it was announced, and its introduction in 2018. In the UK more than 20% of people regularly drink alcohol at levels that increase their health risk. People should also be aware of the less obvious risks posed by drinking alcohol, including the sugar content, and take this into account when choosing their tipple, especially if they are trying to lose weight.
Vitamin D2 and D3: what’s the difference and which should you take?
Vitamin D is important for maintaining health, as it has many roles in the human body. But there is more than one form of vitamin D, and recent research suggests that these forms may have different effects. So what are the different types of vitamin D, and is one really more beneficial than the other? Although medical conditions later associated with vitamin D deficiency, such as the bone disease rickets, have been known about since the 17th century, vitamin D itself wasn’t identified until the early 20th century. This discovery led to Adolf Windaus winning the Nobel prize for chemistry in 1928. The vitamin D family actually includes five molecules, with the two most important being vitamin D2 and D3. These molecules are also known as ergocalciferol and cholecalciferol, respectively. While both of these types of vitamin D contribute to our health, they differ in how we get them. Dietary vitamin D2 generally comes from plants, particularly mushrooms and yeast, whereas we get vitamin D3 from animal sources, such as oily fish, liver and eggs. Both forms of vitamin D are also available in dietary supplements. What most people probably don’t know is that most of our vitamin D comes from exposing our skin to sunlight. When our skin is exposed to the sun, ultraviolet rays convert a precursor molecule called 7-dehydrocholesterol into vitamin D3. This important effect of exposure to the sun explains why people living at more extreme latitudes, or people who have darker skin, are more prone to vitamin D deficiency. Melanin, a pigment in the skin, blocks ultraviolet rays from activating 7-dehydrocholesterol, thus limiting D3 production. Wearing clothing or sunscreen has a similar effect. Both vitamins D2 and D3 are essentially inactive until they go through two processes in the body. First, the liver changes their chemical structure to form a molecule known as calcidiol. This is the form in which vitamin D is stored in the body. Calcidiol is then further altered in the kidneys to form calcitriol, the active form of the hormone. It is calcitriol that is responsible for the biological actions of vitamin D, including helping bones to form, metabolising calcium and supporting how our immune system works. Technically, vitamin D isn’t a vitamin at all, but a pro-hormone. This means the body converts it into an active hormone. All hormones have receptors (on bone cells, muscle cells, white blood cells) that they bind to and activate, like a key unlocking a lock. Vitamin D2 has the same affinity for the vitamin D receptor as vitamin D3, meaning neither form is better at binding to its receptor. Different effects on the immune system A recent study found that vitamin D2 and D3 supplementation had different effects on genes important for immune function. These findings are significant, as most previous research has failed to find much difference in the effect of supplementation with either vitamin D2 or D3. Most of the research published to date has suggested that the main difference between vitamin D2 and D3 supplementation is the effect on circulating vitamin D levels in the bloodstream. Studies have repeatedly shown that vitamin D3 is superior at raising levels of vitamin D in the body. These findings were supported by a recent review of the evidence which found that vitamin D3 supplementation increased vitamin D levels in the body better than vitamin D2. But not all studies agree. Very few studies support vitamin D2 supplementation being superior to vitamin D3. One trial showed that vitamin D2 was better at treating immune issues in patients who were on steroid therapy. However, other than increasing vitamin D levels in the body, there is not much evidence that vitamin D3 supplements are better than vitamin D2 supplements. One study found that vitamin D3 improved calcium levels more than vitamin D2. But we need more research to provide definitive answers. So which should I take? Vitamin D deficiency is now more prevalent than ever, with around a billion people worldwide being vitamin D deficient. It is important that people at risk of vitamin D deficiency – older adults, people living in less sunny climates and people with darker skin – take vitamin D supplements. Health professionals recommend that most people take 10 micrograms of vitamin D a day, especially in winter. It would appear that vitamin D3 supplements are the superior option for maintaining vitamin D levels, but short exposure of the skin to the sun, even on a cloudy day, will also help you keep healthy vitamin D levels.
Villa Vision provides over 2,000 inner-city children with the tools to improve educational prospects
Villa Vision, an innovative collaboration between Aston University, the Aston Villa Foundation and optical lens supplier Essilor Vision For Life is celebrating the end of its second year having engaged with around 4,500 individuals to raise awareness around the importance of eye health and equip inner-city children with the tools to learn in order to enhance their educational experience and help with their longer-term prospects. Launched in 2020 and delivered by the Aston Villa Foundation, the initiative was the first of its kind in the UK and sought to deliver a programme of eye-health awareness lessons in the classroom, free vision and colour vision screening, followed by a more comprehensive eye test and free glasses to those children who require them, using a fully operational custom-designed mobile eye care unit. With the successful completion of Villa Vision’s second Autumn Term in December, a challenging yet successful year means that the project has now benefited schoolchildren in many local inner-city schools, including: Over 2,200 children receiving the Villa Vision workshop across 30 schools Almost 1,800 children having a vision and colour vision screening check in local primary schools Approximately 280 children (around 16%) being flagged for further investigation Around 100 fully comprehensive eye tests being conducted at schools using the Villa Vision eyecare van Nearly 120 pairs of glasses being provided to children requiring them, helping to support both their educational and social development. Nikhil Sonpal, Villa Vision Project Manager and optometrist at Aston Villa Foundation, said: “The Villa Vision team is extremely proud to have directly reached several thousand local children in supporting their visual health and eye care knowledge through the Foundation’s established network of local primary schools and community organisations.” Leon Davies, professor of optometry and physiological optics in the School of Optometry at Aston University and Vice President of the College of Optometrists said: “We are delighted to see the results that our clinical and research expertise in evidence-based eye care is providing our local community. “The provision of free eye care and raising awareness of the importance of eye health is vital in increasing the long-term prospects of schoolchildren and I am looking forward to future developments of the project in 2022.” Funded by the Premier League, the Professional Footballers’ Association (PFA) and Aston University and delivered by the Aston Villa Foundation, the project is designed to fill a crucial lack of knowledge surrounding the importance of having an eye test and how preventative measures can ensure, among a host of benefits, a lifetime of good vision.
