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Aston University wins grant to make research more sustainable and environmentally friendly featured image

Aston University wins grant to make research more sustainable and environmentally friendly

University awarded grant to develop more sustainable separation method through AstraZeneca’s Open Innovation CoSolve Challenge at ELRIG Dr Vesna Najdanovic will explore use of the solvent ethyl lactate It is a biorenewable and environmentally friendly alternative. An Aston University scientist has won a $25000 grant in the AstraZeneca Open Innovation CoSolve sustainability challenge to help to make research more sustainable and environmentally friendly. Dr Vesna Najdanovic, senior lecturer in chemical engineering at the University’s Energy and Bioproducts Research Institute (EBRI), successfully pitched her idea to explore a new method using ethyl lactate as a solvent. Ethyl lactate is a biorenewable and environmentally friendly alternative solvent produced from lactic acid and ethanol, both obtained by fermentation of biomass. Currently hazardous organic solvents such as acetonitrile are widely used instead. Dr Najdanovic won the AstraZeneca’s Open Innovation CoSolve Sustainability Challenge at the European laboratory research & innovation group (ELRIG) Research and Innovation meeting. She said: “Throughout my research career, I have been working with various green solvents, such as supercritical fluids, ionic liquids and biosolvents, to improve chemical and separation processes. “I am delighted to be selected by the expert judging panel and the highly engaged audience to apply my knowledge to develop greener analytical methods using ethyl lactate as a solvent for liquid chromatography. “I hope this project will pave the pathway to use this environmentally friendly alternative solvent while reducing carbon footprint and pollution”. The pharmaceutical industry generates the highest amount of waste per mass of products compared to other chemical industry sectors, such as the petroleum industry, bulk and fine chemicals. Dr Kelly Gray, CoSolve sustainability programme lead at AstraZeneca, said “In order to protect people, society and planet we have to identify and develop solutions to deliver sustainable science. The goal of the CoSolve sustainability programme was to do just that and identify innovative ideas to practical challenges faced by researchers across scientific disciplines in R&D.” Sanj Kumar, CEO of ELRIG, said “Ensuring that drug discovery processes become sustainable is a priority issue to the ELRIG community, so partnering with AstraZeneca on the CoSolve initiative, by hosting the pitching and final award ceremony, is not only an honour, but raises the awareness of sustainability to our community. Dr Najdanovic and her innovation are a worthy winner and ELRIG is proud that we are able to share her success story.” As much as 80% of this waste presents hazardous organic solvents obtained from petrochemical sources. For example, the pharmaceutical industry consumes 50% of globally produced acetonitrile, of which 20% is a solvent for liquid chromatography, a widely used analytical tool in research and development laboratories. After its use, most acetonitrile is discarded as chemical waste and subsequently incinerated, generating greenhouse gases and other pollutants such as nitrogen oxides and highly toxic hydrogen cyanide. The CoSolve sustainability challenge award builds on Dr Najdanovic’s previous work employing ethyl lactate as a solvent for various separation processes. Her new project supports EBRI’s wider objectives of using bioproducts to deliver low-carbon and environmentally sustainable solutions.

3 min. read
Gene Editing Institute Opens a Unique Learning Lab for High School and College Students featured image

Gene Editing Institute Opens a Unique Learning Lab for High School and College Students

Free program uses CRISPR in a Box™ toolkit to teach the power of gene editing To inspire the next generation of students to pursue careers in STEM (science, technology, engineering and math) and learn about the power of genomic science, ChristianaCare’s Gene Editing Institute has launched a new Learning Lab on its premises that offers educational programming about revolutionary CRISPR gene editing technology. Located next to the Gene Editing Institute’s lab on the University of Delaware’s STAR Campus, the Learning Lab is a physical space that provides an immersive field trip experience for upper-level high school students and college undergraduates who may not have access at their schools to a laboratory to conduct gene editing experiments. There is no cost for schools to use the lab or for the materials to conduct the experiment. The Gene Editing Institute wants to ensure that all schools have equal opportunity to participate in educational programming at the lab. Students using the lab can perform a gene editing experiment in a single day using the Gene Editing Institute’s innovative CRISPR in a Box™ educational toolkit. All materials in the kit are safe, synthetic materials, and allow students to perform CRISPR gene editing with non-infectious E. coli bacteria. They will be able to see an appearance change indicating gene editing has occurred at the end of their experiment. “Students around the country, no matter where they go to school, have the potential to be scientists, researchers and laboratory technicians,” said Eric Kmiec, Ph.D., executive director and chief scientific officer of ChristianaCare’s Gene Editing Institute. “Our hope is that by creating access and space for students to explore, we can inspire the next generation of students to pursue STEM careers. The Learning Lab allows us to help cultivate the next generation of genetic scientists and strengthen Delaware and our region as a leader in biotechnology.” Education Program Manager Amanda Hewes, MS, developed the Learning Lab after noticing a problem that was undercutting the opportunities of teachers to bring gene editing experiments into the classroom — a lack of space and equipment. Amanda Hewes, education program coordinator, assists students from Wilmington Charter School with their samples of DNA during a Learning Lab experiment. “We don’t want anything to hinder the way students learn about CRISPR gene editing,” Hewes said. “If a student feels like there are too many steps, or a teacher doesn’t have an essential piece of equipment, then we’ve lost an opportunity to bring the next generation of scientists into the lab. We’re striving to break down as many barriers as possible for students.” Learning real-world applications of gene editing The Learning Lab also allows students to speak directly with experts in the field about careers in biotechnology and gene editing as they learn the difference between such things as phenotypic and genotypic readouts in their gene editing experiments. This gives students the chance to ask about the real-world application of genome experiments in a research lab. It also lets them think about their place in a lab setting. “I’ve never been in an actual lab setting before,” said Shiloh Lee, a junior at the Charter School of Wilmington, at a recent class. “I think it is very, very cool to be able to experience it.” “I’ve learned a lot of new skills with the micropipetting,” said Pauline Zhuang, a senior at The Charter School of Wilmington. “We don’t have the same resources at our school. The CRISPR in a Box is such a great resource. My classmates and I have been able to experience, firsthand, what it is like to actually do gene editing.” Through the program, the Gene Editing Institute hopes to educate 1,000 students by spring 2024. Currently, the lab is on track to engage more than 200 students by the end of the spring 2023 semester. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas 9 genome editing technology. The CRISPR technology enables researchers to modify genes in living cells and organisms and may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease. For more information about the Learning Lab and the educational program, email geneeditinginstitute@christianacare.org.

Eric Kmiec, Ph.D profile photo
3 min. read
Public lecture: My career in five equations, and the importance of mathematics education in the digital age featured image

Public lecture: My career in five equations, and the importance of mathematics education in the digital age

• Professor Stephen Garrett to discuss why the UK needs to up its game in maths education • He has a particular interest in the development of mathematical and computational solutions to real-world problems • Lecture will take place on Thursday 27 April at Aston University. The latest inaugural lecture at Aston University is to explore why the UK’s low level of mathematical skills don’t add up to a positive digital future. Professor Stephen Garrett will discuss why school-level mathematics is so important in many areas of life and will discuss how the UK needs to up its game in maths education at all ages for the modern digital world. Currently just half of all 16–19-year-olds study maths. Earlier this year the Prime Minister proposed that all students in England will study some form of maths to 18 to ensure that they leave school better equipped for the jobs of the future. Professor Garrett joined Aston University in spring 2022 as Pro-Vice-Chancellor and Executive Dean of the College of Engineering and Physical Sciences. Stephen said: “I’m concerned that too many people are being held back by poor maths – not just at work but in their personal lives too. “Improving maths skills at any age can bring confidence, open up more career options and benefit the local and national economy.” The professor’s research interests are at the boundary of applied mathematics with other disciplines and he has a particular interest in the development of mathematical and computational solutions to real-world problems. He is primarily known as a fluid dynamicist. As an academic leader, Stephen is particularly keen to develop synergies between teaching and research activities and believes the two should always be closely intertwined within the HE sector. His talk, My career in five equations, and the importance of mathematics education in the digital age will also explore the importance of some key areas of school mathematics in his research career. He will start with traditional classroom maths topics such as Pythagoras and trigonometry, through familiar sounding concepts and will link them to a model for fluid flows relevant to the aerospace sector. The free event will take place on the University campus at Conference Aston, on Thursday 27 April from 6 pm to 8 pm and will be followed by a drinks reception. To sign up for a place visit https://www.eventbrite.co.uk/e/an-inaugural-lecture-by-professor-aniko-ekart-tickets-516518760517 There are more details about mathematics courses at Aston University at https://www.aston.ac.uk/courses/mathematics

2 min. read
Aston University develops software to untangle genetic factors linked to shared characteristics among different species

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Aston University develops software to untangle genetic factors linked to shared characteristics among different species

• Has potential to help geneticists investigate vital issues such as antibacterial resistance • Will untangle the genetic components shared due to common ancestry from the ones shared due to evolution • The work is result of a four-year international collaboration. Aston University has worked with international partners to develop a software package to help scientists answer key questions about genetic factors associated with shared characteristics among different species. Called CALANGO (comparative analysis with annotation-based genomic components), it has the potential to help geneticists investigate vital issues such as antibacterial resistance and improvement of agricultural crops. This work CALANGO: a phylogeny-aware comparative genomics tool for discovering quantitative genotype-phenotype associations across species has been published in the journal Patterns. It is the result of a four year collaboration between Aston University, the Federal University of Minas Gerais in Brazil and other partners in Brazil, Norway and the US. Similarities between species may arise either from shared ancestry (homology) or from shared evolutionary pressures (convergent evolution). For example, ravens, pigeons and bats can all fly, but the first two are birds whereas bats are mammals. This means that the biology of flight in ravens and pigeons is likely to share genetic aspects due to their common ancestry. Both species are able to fly nowadays because their last common ancestor – an ancestor bird - was also a flying organism. In contrast, bats have the ability to fly via potentially different genes than the ones in birds, since the last common ancestor of birds and mammals was not a flying animal. Untangling the genetic components shared due to common ancestry from the ones shared due to common evolutionary pressures requires sophisticated statistical models that take common ancestry into account. So far, this has been an obstacle for scientists who want to understand the emergence of complex traits across different species, mainly due to the lack of proper frameworks to investigate these associations. The new software has been designed to effectively incorporate vast amounts of genomic, evolutionary and functional annotation data to explore the genetic mechanisms which underly similar characteristics between different species sharing common ancestors. Although the statistical models used in the tool are not new, it is the first time they have been combined to extract novel biological insights from genomic data. The technique has the potential to be applied to many different areas of research, allowing scientists to analyse massive amounts of open-source genetic data belonging to thousands of organisms in more depth. Dr Felipe Campelo from the Department of Computer Science in the College of Engineering and Physical Sciences at Aston University, said: “There are many exciting examples of how this tool can be applied to solve major problems facing us today. These include exploring the co-evolution of bacteria and bacteriophages and unveiling factors associated with plant size, with direct implications for both agriculture and ecology.” “Further potential applications include supporting the investigation of bacterial resistance to antibiotics, and of the yield of plant and animal species of economic importance.” The corresponding author of the study, Dr Francisco Pereira Lobo from the Department of Genetics, Ecology and Evolution at the Federal University of Minas Gerais in Brazil, said: “Most genetic and phenotypic variations occur between different species, rather than within them. Our newly developed tool allows the generation of testable hypotheses about genotype-phenotype associations across multiple species that enable the prioritisation of targets for later experimental characterization.” For more details about studying computer since at Aston University visit https://www.aston.ac.uk/eps/informatics-and-digital-engineering/computer-science

3 min. read
Researchers fight cybercrime with new digital forensic tools and techniques featured image

Researchers fight cybercrime with new digital forensic tools and techniques

Irfan Ahmed, Ph.D., associate professor of computer science, provides digital forensic tools — and the knowledge to use them — to the good guys fighting the never-ending cyber-security war. Ahmed is director of the Security and Forensics Engineering (SAFE) Lab within the Department of Computer Science and VCU Engineering. He leads a pair of interrelated projects funded by the U.S. Department of Homeland Security (DHS) aimed at keeping important industrial systems safe from the bad guys — and shows the same tools crafted for investigating cyber attacks can be used to probe other crimes. The goal of cyber attacks on physical infrastructure may be to cause chaos by disrupting systems and/or to hold systems for ransom. The SAFE lab focuses on protecting industrial control systems used in the operation of nuclear plants, dams, electricity delivery systems and a wide range of other elements of critical infrastructure in the U.S. The problem isn’t new: In 2010, the Stuxnet computer worm targeted centrifuges at Iranian nuclear facilities before getting loose and infecting “innocent” computers around the world. Cyber attacks often target a portion of the software architecture known as the control logic. Control logic is vulnerable in that one of its functions is to receive instructions from the user and hand them off to be executed by a programmable logic controller. For instance, the control logic monitoring a natural gas pipeline might be programmed to open a valve if the system detects pressure getting too high. Programmers can modify the control logic — but so can attackers. One of Ahmed’s DHS-supported projects, called “Digital Forensic Tools and Techniques for Investigating Control Logic Attacks in Industrial Control Systems,” allows him to craft devices and techniques that cyber detectives can use in their investigations of attacks on sensitive critical infrastructure. Their investigation capabilities, he explains, is an under-researched area, as most of the emphasis to date has been on the prevention and detection of their cyber attacks. “The best scenario is to prevent the attacks on industrial systems,” Ahmed said. “But if an attack does happen, then what? This is where we try to fill the gap at VCU. And the knowledge that we gain in a cyber attack investigation can further help us to detect or even prevent similar attacks.” In the cat-and-mouse world of cyber security, the way cybercriminals work is in constant evolution, and Ahmed’s SAFE lab pays close attention to the latest developments by malefactors. For instance, an attacker may go for a more subtle approach than modifying the original control logic. An attack method called return-oriented programming sees the malefactor using the existing control logic code, but artfully switching the execution sequence of the code. Other attackers might insert their malware into another area of the controller, programmed to run undetected until it can replace the function of the original control logic. Attackers are always coming up with new methods, but each attack leaves evidence behind. The SAFE lab examines possible attack scenarios through simulations. Scale models of physical systems, including an elevator and a belt conveyor system, are housed at the SAFE lab to help facilitate this. The elevator is a four-floor model with inside and outside buttons feeding into a programmable logic controller. The conveyor belt is more advanced, equipped with inductive, capacitive and photoelectric sensors and able to sort objects. The tools and methods applied in cybercrime can be useful in tracking down other malefactors. That’s where Ahmed’s second DHS-funded project comes in. It’s called “Data Science-integrated Experiential Digital Forensics Training based-on Real-world Case Studies of Cybercrime Artifacts.” Ahmed is the principal investigator, working with co-PI Kostadin Damevski, Ph.D., associate professor of computer science. The goal is to keep law enforcement personnel abreast of the latest trends in the field of cybercrime investigation and to equip them with the latest tools and techniques, including those developed in the SAFE lab. “For example, investigators often have to go through thousands of images, or emails or chats, looking for something very specific,” Ahmed said. “We believe the right data science tools can help them to narrow down that search.” The FBI and other law enforcement agencies already have dedicated cybersleuthing units; the Virginia State Police have a computer evidence recovery section in Richmond. Ahmed and Damevski are arranging sessions showing investigators how techniques from data science and machine learning can make investigations more efficient by sorting through the mounds of digital evidence that increasingly is a feature of modern crime.

Irfan Ahmed, Ph.D. profile photoKostadin Damevski, Ph.D. profile photo
3 min. read
Society matters LIVE: Lab made meat on the menu?

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Society matters LIVE: Lab made meat on the menu?

• Research at Aston University focuses on both creating lab-based meat and its psychological acceptance • Dr Eirini Theodosiou and Dr Jason Thomas will be speaking at April’s Society matters LIVE event • Lab made meat on the menu? will take place at Cafe Artum in Hockley Social Club on Thursday 27 April. Lab made meat will be the topic of the latest Society matters LIVE event from Aston University at Café Artum at Birmingham’s Hockley Social Club on Thursday 27 April. Dr Eirini Theodosiou and Dr Jason Thomas at Aston University are conducting research into lab-made or cultivated meat, both exploring the creation of the meat and the psychological impact of the product. Dr Eirini Theodosiou, senior lecturer in the School of lnfrastructure and Sustainable Engineering, focuses on ways to produce enough cell mass to create the meat. Meanwhile Dr Jason Thomas’ work explores the psychology behind supporting people to accept lab-made food. The research comes as current trends indicate that demand for animal-based foods will increase by 70% in 2050 to feed the predicted 9.8 billion people. Dr Theodosiou said: “Cultivated or lab grown meat offers a safer, more sustainable and animal cruelty-free alternative for consumers. It is a very young industry trying to replace traditional meat production methods however, with 800 million people worldwide suffering from hunger and malnutrition, it is a viable option.” “In addition, the livestock industry is responsible for 12-18% of the total greenhouse gas emissions and is a cause of deforestation. Increased meat production and factory farming are the topmost likely causes of the next pandemic due to the extensive use of antibiotics and increasing emergence of zoonotic diseases.” Dr Thomas said: “It is a relatively new food technology, and much work still needs to be done to make it affordable and on a massive scale. We are interested in finding out what factors can influence consumer purchase of and consumption of lab-made meat.” The event is organised by Aston University and Café Artum at Hockley Social Club as part of the Society matters LIVE series. Free tickets are available at https://www.eventbrite.co.uk/e/lab-made-meat-on-the-menu-tickets-464161147487?aff=ebdsoporgprofile

Dr Eirini Theodosiou profile photo
2 min. read
Ask an Expert: Is the "AI Moratorium" too far reaching? featured image

Ask an Expert: Is the "AI Moratorium" too far reaching?

Recent responses to chatGPT have featured eminent technologists calling for a six-month moratorium on the development of “AI systems more powerful than GPT-4.” Dr. Jeremy Kedziora, PieperPower Endowed Chair in Artificial Intelligence at Milwaukee School of Engineering, supports a middle ground approach between unregulated development and a pause. He says, "I do not agree with a moratorium, but I would call for government action to develop regulatory guidelines for AI use, particularly for endowing AIs with actions." Dr. Kedziora is available as a subject matter expert on the recent "AI moratorium" that was issued by tech leaders. According to Dr. Kedziora: There are good reasons to call for additional oversight of AI creation: Large deep or reinforcement learning systems encode complicated relationships that are difficult for users to predict and understand. Integrating them into daily use by billions of people implies some sort of complex adaptive system in which it is even more difficult for planners to anticipate, predict, and plan. This is likely fertile ground for unintended – and bad – outcomes. Rather than outright replacement, a very real possibility is that AI-enabled workers will have sufficiently high productivity that we’ll need less workers to accomplish tasks. The implication is that there won’t be enough jobs for those who want them. This means that governments will need to seriously consider proposals for UBI and work to limit economic displacement, work which will require time and political bargaining. I do not think it is controversial that we would not want a research group at MIT or CalTech, or anywhere developing an unregulated nuclear weapon. Given the difficulty in predicting its impact, AI may well be in the same category of powerful, suggesting that its creation should be subject to the democratic process. At the same time, there are some important things to keep in mind regarding chatGPT-like AI systems that suggest there are inherent limits to their impact: Though chatGPT may appear–at times–to pass the famous Turing test, this does not imply these systems ’think,’ or are ’self-aware,’ or are ’alive.’ The Turing test aims to avoid answering these questions altogether by simply asking if a machine can be distinguished from a human by another human. At the end of the day, chatGPT is nothing more than a bunch of weights! Contemporary AIs–chatGPT included–have very limited levers to pull. They simply can’t take many actions. Indeed, chatGPT’s only action is to create text in response to a prompt. It cannot do anything independently. Its effects, for now, are limited to passing through the hands of humans and to the social changes it could thereby create. The call for a moratorium emphasizes ‘control’ over AI. It is worth asking just what this control means. Take chatGPT as an example–can its makers control responses to prompts? Probably only in a limited fashion at best, with less and less ability as more people use it. There simply aren’t resources to police its responses. Can chatGPT’s makers ‘flip the off switch?’ Absolutely – restricting access to the API would effectively turn chatGPT off. In that sense, it is certainly under the same kind of control humans subjected to government are. Keep in mind that there are coordination problems – just because there is an AI moratorium in the US does not mean that other countries–particularly US adversaries– will stop development. And as others have said: “as long as AI systems have objectives set by humans, most ethics concerns related to artificial intelligence come from the ethics of the countries wielding them.” There are definitional problems with this sort of moratorium – who would be subject to it? Industry actors? Academics? The criterion those who call for the moratorium use is “AI systems more powerful than GPT-4.” What does “powerful” mean? Enforcement requires drawing boundaries around which AI development is subject to a moratorium – without those boundaries how would such a policy be enforced? It might already be too late – some already claim that they’ve recreated chatGPT. There are two major groups to think about when looking for develop regulatory solutions for AI: academia and industry. There may already be good vehicles for regulating academic research, for example oversight of grant funding. Oversight of AI development in industry is an area that requires attention and application of expertise. If you're a journalist covering Artificial Intelligence, then let us help. Dr. Kedziora is a respected expert in Data Science, Machine Learning, Statistical Modeling, Bayesian Inference, Game Theory and things AI. He's available to speak with the media - simply click on the icon now to arrange an interview today.

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4 min. read
Protein engineer to explore route from DNA blueprint to synthetic antibodies – public lecture featured image

Protein engineer to explore route from DNA blueprint to synthetic antibodies – public lecture

Professor Anna Hine will explore how advances in protein engineering have enabled us to make both synthetic antibodies and their replacements Inaugural lecture will take place at Aston University on Tuesday 28 March 2023 at 6.30pm Members of the public may attend in person or online. Professor Anna Hine, a molecular biologist specialising in protein engineering in the College of Health and Life Sciences at Aston University, is to present her inaugural public lecture on Tuesday 28 March 2023. During her lecture, A route to synthetic antibodies (and their replacements), Professor Hine will take the audience from the basics of molecular biology to explaining her inventions in protein engineering, through to examining the ways in which her research is being applied internationally to develop synthetic antibodies. Professor Hine gained her PhD in molecular biology from The University of Manchester Institute of Science and Technology in 1992 and did her postdoctoral training at Harvard Medical School. She returned to the UK to take up a lectureship in molecular biology at Aston University in 1995. Professor Anna Hine, professor of protein engineering, said: “Antibodies are one of our major lines of defence against infection and we can create them very quickly to help incapacitate a multitude of biological invaders. Humans do this by changing the part of the antibody that recognises the invading pathogen, through a process of rapid, natural mutation. Protein engineers have learned to mimic this process in the laboratory to create synthetic proteins – particularly antibodies - for use in both therapy and fundamental research.” “I am delighted to have the opportunity to present our discoveries in a way that I hope will make just as much sense to non-scientists as to a scientific audience.” Similar to the natural mutation of antibodies, protein engineers can make vast numbers of tiny variations of a protein such as an antibody. Professor Hine added: “We will contemplate the vast numbers involved in protein engineering and present how our Aston University-based inventions have made the creation of DNA (and thus protein) ‘libraries’ as efficient as possible. “We will then examine the ensuing problem of how to find the few proteins that we really want from within a protein library. This includes collaborating with experts who specialise in computer-assisted library design and also working with those who have developed the latest methods to search the libraries that we make.” Professor Hine will also show how her latest collaborative projects are starting to move beyond the antibody itself. The lecture will take place at Aston University at 6.00pm for 6.30pm on Tuesday 28 March 2023. It will be followed by a drinks reception from 7.30 pm to 8.00 pm. The lecture is open to the public and free to attend. Places must be booked in advance via Eventbrite.

2 min. read
Aston Institute of Health and Neurodevelopment celebrates British Science Week and Brain Awareness Week featured image

Aston Institute of Health and Neurodevelopment celebrates British Science Week and Brain Awareness Week

• Institute of Health and Neurodevelopment to host children’s activities at Birmingham’s science museum Thinktank on Saturday 18 March • British Science Week is a ten-day celebration of science, technology, engineering and maths • Brain Awareness Week highlighted with research showcased in glass box exhibition space on University campus. Aston Institute of Health and Neurodevelopment (IHN) is celebrating British Science Week (10-19 March) and Brain Awareness Week (13-19 March) by hosting an activities day for children at the Birmingham science museum Thinktank, alongside a social media campaign to help educate and inform the public on its latest research. Each year, the British Science Association runs a ten-day celebration of science, technology, engineering and maths called British Science Week. It is closely followed by Brain Awareness Week, a yearly global campaign to increase public awareness of brain research. The week-long celebration is organised by the Dana Alliance with a goal to educate and highlight the importance of research in developing new treatments, preventions and possible cures for brain diseases. Both campaigns align closely with the work of the Aston Institute of Health and Neurodevelopment, with the Institute’s researchers keen to use the week to host activities and share their research and information about the brain health with the public. Activities to highlight both British Science Week and Brain Awareness week include a social media campaign sharing research updates from members and surprising brain facts on Twitter (@Aston_IHN), a brain research exhibition in the glass box space in the Aston University main entrance, as well as an activity session at the Birmingham science museum Thinktank in Millennium Point. The meet and greet with IHN researchers will take place on Saturday 18 March between 11.00 and 16.00. Children and families can speak to researchers about their work and take part in interactive activities, such as memory games and eye-tracking experiments. Professor Jackie Blissett, co-director of IHN said: “British Science week and Brain Awareness week are really important campaigns for us. Brain Awareness week is the perfect time to showcase our research and engage with the public on what we do here at IHN. “We work in close collaboration with the NHS to help research potential treatments for children who experience a range of brain related conditions. We put children at the heart of what we do, with the aim of unlocking the potential of research to support children’s health and development as well as answering the questions that matter to children, their families and the services that support them.” Visitors to the exhibition on the Aston University campus are encouraged to share their thoughts about the exhibition and their pictures on Twitter, tagging @Aston_IHN. For more information about Aston Institute of Health and Neurodevelopment visit its website and for more information about studying psychology and neuroscience at Aston University visit our course pages.

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2 min. read
AI-powered cruise control system may pave the way to fuel efficiency and traffic relief featured image

AI-powered cruise control system may pave the way to fuel efficiency and traffic relief

The CIRCLES Consortium, consisting of Vanderbilt University, UC Berkeley, Temple University and Rutgers University-Camden, in coordination with Nissan North America and the Tennessee Department of Transportation, concluded a five-day open-track experiment on Nov. 18. Congestion Impacts Reduction via CAV-in-the-loop Lagrangian Energy Smoothing (CIRCLES) Researchers tested an AI-powered cruise control system designed to increase fuel savings and ease traffic using 100 specially equipped Nissan Rogue vehicles. The experiment—which ran from Nov. 14 through Nov. 18 on a sensor-filled portion of Interstate 24—is based on the results from an earlier, closed-track study where a single smart vehicle smoothed human-caused traffic congestion, leading to significant fuel savings. A single AI-equipped vehicle could influence the speed and driving behavior of up to 20 surrounding cars, causing a kind of positive ripple effect in day-to-day traffic. The CIRCLES Consortium will spend the next several months analyzing data collected on the AI-equipped vehicles and their impact on the flow of traffic over the duration of the experiment. The test was conducted on the recently opened I-24 MOTION testbed, the only real-world automotive testing environment of its kind in the world. Stretching for four miles just southeast of downtown Nashville, the smart highway is equipped with 300 4K digital sensors capable of logging 260,000,000 vehicle-miles of data per year. The CIRCLES Consortium research is supported by the National Science Foundation and the U.S. Departments of Transportation and Energy. Support was also provided by Toyota North America and General Motors. The experiment included Toyota RAV4 and Cadillac XT5 vehicles. Preliminary vehicle and traffic flow detection in the I-24 Mobility Technology Interstate Observation Network (MOTION). “On November 16 alone, the system recorded a total of 143,010 miles driven and 3,780 hours of driving. The I-24 MOTION system, combined with vehicle energy models developed in the CIRCLES project, provided an estimation of the fuel consumption of the whole traffic flow during those hours. The concept we are hoping to demonstrate is that by leveraging this new traffic system to collect data and estimate traffic and applying artificial intelligence technology to existing cruise control systems, we can ease traffic jams and improve fuel economy,” the CIRCLES team said in a joint statement. “Nissan has always been a pioneer in automotive innovation, and with our long-term vision, Nissan Ambition 2030, we know our future is autonomous, connected and electric,” said Liam Pedersen, deputy general manager at the Nissan Alliance Innovation Lab in California’s Silicon Valley. “CIRCLES shares our common goal of building a safer, cleaner world by empowering mobility.” “When it comes to transportation and mobility in Tennessee, we are at a critical juncture,” said Deputy Governor and TDOT Commissioner Butch Eley. “Traffic congestion is now becoming more prominent throughout Tennessee, and not just in urban areas. Addressing these challenges will force us to think critically about solutions, as transportation infrastructure projects traditionally are not identified nor completed before traffic congestion more dramatically affects our quality of life. One of these solutions is greater use of technology to enhance mobility. We are confident that this project and others like it will further strengthen Tennessee’s reputation for being a hub of automotive excellence.” “The I-24 MOTION project is a first-of-its-kind testbed, where we’ll be able to study in real time the impact connected and autonomous vehicles have on traffic in an open road setting,” said Meredith Cebelak, adjunct instructor in civil and environmental engineering at Vanderbilt and Tennessee transportation and transportation systems management and operations department leader at Gresham Smith. “The permanent infrastructure has been designed and installed, meaning the testbed will always be ‘on’ and available to researchers. By unlocking a new understanding of how these vehicles influence traffic, vehicle, infrastructure, and traffic management strategies, design can be optimized to reduce traffic concerns in the future to improve safety, air quality and fuel efficiency.”  “Partnership across universities, government and the private sector is the key to pioneering projects like this one,” Vice Provost for Research and Innovation Padma Raghavan said. “From its earliest inception, all the partners in this effort have played vital roles. That trusted collaboration continues as the team analyzes results to seek new insights to address pressing challenges in transportation in Tennessee and beyond.”

Dan Work profile photo
3 min. read