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Ram B. Gupta, Ph.D. - VCU College of Engineering. Engineering West Hall, Suite 331, Richmond, VA, US

Ram B. Gupta, Ph.D. Ram B. Gupta, Ph.D.

Associate Dean for Faculty Research Development | Professor of Chemical & Life Science Engineering | VCU College of Engineering

Engineering West Hall, Suite 331, Richmond, VA, UNITED STATES

Research interest: batteries, electrochemistry, sustainable energy, biofuel, supercritical fluids, and nanomedicine.

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Biography

Dr. Gupta is the Associate Dean for Research and a Professor in the School of Engineering at the Virginia Commonwealth University, Richmond, VA. Prior to joining VCU, during 2011-2014, he served as the Director of Energy for Sustainability Program at the National Science Foundation. This program supports fundamental research and education that will enable innovative processes for the sustainable production of electricity and transportation fuels. Processes for sustainable energy production must be environmentally benign, reduce greenhouse gas production, and utilize renewable resources. Projects include those related to biofuels, photovoltaic solar energy, wind energy, and advanced batteries for transportation. During 1995-2014, he was a professor of chemical engineering at Auburn University. He has published numerous research papers and patents on pharmaceuticals and fuels, and is the recipient of Wright A. Gardner Award (2013) from the Alabama Academy of Science, Distinguished Graduate Faculty Lectureship award (2007) from Auburn University, Science and Engineering Award (2002-2004) from DuPont, Junior and Senior Research awards (1998, 2002, 2009) from Auburn Alumni Engineering Council, the James A. Shannon Director’s Award (1998) from the National Institutes of Health, and Young Faculty Career Enhancement Award (1997) from Alabama NSF-EPSCoR.

He is a Fellow of Alabama Academy of Science (2008) and serves/served on the editorial advisory boards various journals including ACS Sustainable Chemistry & Engineering, Industrial & Engineering Chemistry Research, Nanomedicine: Nanotechnology, Biology and Medicine (2005-07), Journal of Biomedical Nanotechnology, Research Letters in Nanotechnology, and Research Letters in Chemical Engineering. He received the B.E. degree (1987) from Indian Institute of Technology, Roorkee, the M.S. degree (1989) from the University of Calgary, and the Ph.D. degree (1993) from the University of Texas at Austin, all in chemical engineering. During 1993-95, he did postdoctoral work at the University of California, Berkeley. His recent books are: Nanoparticle Technology for Drug Delivery (2006, Taylor & Francis), Solubility in Supercritical Carbon Dioxide (2007, CRC Press), Hydrogen Fuel: Production, Transport, and Storage (2008, CRC Press), Gasoline, Diesel and Ethanol Biofuels from Grasses and Plants (Cambridge University Press, 2010), and Compendium of Hydrogen Energy (Elsevier, 2015).

Industry Expertise (7)

Energy Pharmaceuticals Cleantech Nanotechnology Chemicals Research Education/Learning

Areas of Expertise (19)

Batteries Electrochemical engineering Bio-carbon Supercritical carbon dioxide technology Nanotechnology Nanoparticles Nanomedicine Controlled release Nanomixing Smart medicine Supercritical water technology Hydrogen fuel Renewable fuels Bio-energy Liquid fuels from methane and biomass CO2 sequestration Photochemical engineering Oil spill remediation using benign dispersants Renewable materials

Education (4)

University of California, Berkeley: Postdoc, Chemical Engineering 1995

The University of Texas at Austin: Ph.D., Chemical Engineering 1993

University of Calgary: M.S., Chemical Engineering 1989

Indian Institute of Technology, Roorkee: B.E., Chemical Engineering 1987

Research Focus (3)

Batteries and Supercapacitors

Use of novel electrochemical engineering and materials technology to improve batteries and supercapacitors for cell phones and cars.

Pharmaceutical manufacturing

Use of electro-catalysis and nanotechnology to simplify pharmaceutical manufacturing pathways.

Sustainable fuel

Use of supercritical water technology to produce fuel and bio-carbon from biomass.

Patents (6)

Particulate vaccine formulations for inducing innate and adaptive immunity

US 20170072051 A1

2017-03-16

Disclosed are compositions, kits, and methods for inducing an immune response against an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter that such that the biodegradable particles are phagocytosed by antigen presenting cells when the biodegradable particles are administered to a subject in need thereof. Optionally, the compositions include one or more of an adjuvant, an apoptosis inhibitor, and an antigen. The compositions, kits, and methods may be utilized to induce a cell-mediated response, such as a T-helper cell response, and/or a humoral response against a pathogen or a disease. In some embodiments, the compositions, kits, and methods may be utilized to induce preferentially a Th1 response versus other types of immune responses such as a Th2 response

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Halloysite Nanotubes and Uses Thereof for Novel Remediation Techniques

US 20160114303 A1

2016-04-28

The creation of novel halloysite-based compositions is disclosed. In one embodiment, the hollow clay nanotubes of halloysite are loaded with nanoscale zerovalent iron particles. The resulting composition provides an effective manner of remediating chlorinated hydrocarbons. In another embodiment, the hollow clay nanotubes of halloysite are imbibed with dispersants such as DOSS and Tween 80 surfactants. The resulting composition stabilizes oil-in-water emulsions and subsequently releases the surfactants, thereby reducing interfacial tension significantly, which allows much smaller droplets to form and thus provides for more effective oil remediation.

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Fabric having ultraviolet radiation protection, enhanced resistance to degradation, and enhanced resistance to fire

US 9234310 B2

2016-01-12

A method for treating a fabric for ultraviolet radiation protection, enhanced resistance to degradation, and enhanced resistance to fire is disclosed which comprises the steps of adding zinc oxide nanoparticles to a solution of 3-glycidyloxypropyl-trimethoxysilane, placing a fabric in the mixture of zinc oxide particles and 3-glycidyloxypropyl-trimethoxysilane, curing the fabric, and washing the fabric. Other methods of treating a fabric are disclosed.

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Biomass to biochar conversion in subcritical water

US 8637718 B2

2014-01-28

A method and system of converting biomass to biochar in a hydrothermal carbonization apparatus wherein subcritical water at a temperature of 230-350° C. and 500-3000 psi is reacted with the biomass to form biochar, biocrude and gases. The method and system include recycling the biocrude back to the hydrothermal carbonization apparatus which improves biochar yield and provides water for the biomass reaction to occur.

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Water stabilization using microparticles

WO 2009020594 A1

2009-02-12

A water stabilization particle comprising: at least one hydrophilic core; and a hydrophobic shell covering the at least one hydrophobic core, wherein the hydrophobic shell is configured to degrade over a period of time, thereby delaying exposure of the at least one hydrophobic core to any liquid that is external to the hydrophobic shell.

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Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer

US 6620351 B2

2003-09-16

The current invention, Supercritical Antisolvent Precipitation with Enhanced Mass Transfer (SAS-EM) provides a significantly improved method for the production of nano and micro-particles with a narrow size distribution. The processes of the invention utilize the properties of supercritical fluids and also the principles of virbrational atomization to provide an efficient technique for the effective nanonization or micronization of particles. Like the SAS technique, SAS-EM, also uses a supercritical fluid as the antisolvent, but in the present invention the dispersion jet is deflected by a vibrating surface that atomizes the jet into fine droplets. The vibrating surface also generates a vibrational flow field within the supercritical phase that enhances mass transfer through increased mixing. Sizes of the particles obtained by this technique are easily controlled by changing the vibration intensity of the deflecting surface, which in turn is controlled by adjusting the power input to the vibration source. A major advantage of the SAS-EM technique is that it can be successfully used to obtain nanoparticles of materials that usually yield fibers or large crystals in SAS method. Microencapsulation via coprecipitation of two or more materials can also be achieved using the SAS-EM technique.

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Selected Articles (38)

Heparin depolymerization by immobilized heparinase: A review Bhushan, Indu; Alabbas, Alhumaidi; Sistla, Jyothi C.; Saraswat, Rashmi; Desai, Umesh R.; Gupta, Ram B., International Journal of Biological Macromolecules 2017, 99, 721-730.

2017

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Solar thermochemical ZnO/ZnSO4 water splitting cycle for hydrogen production, Bhosale, Rahul; Kumar, Anand; Al Momani, Fares; Gupta, Ram B., International Journal of Hydrogen Energy 2017, DOI:10.1016/j.ijhydene.2017.02.190

2017

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Kinetic Study and Modeling of Homogeneous Thermocatalytic Decomposition of Methane over a Ni–Cu–Zn/Al2O3 Catalyst for the Production of Hydrogen and Bamboo-Shaped Carbon Nanotubes Saraswat, Sushil Kumar; Sinha, Bipul; Pant, K. K.; Gupta, Ram B., Industrial & Engineering Chemistry Research 2016, 55(45), 11672-11680.

2016

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CO2 Capture Using Aqueous Potassium Carbonate Promoted by Ethylaminoethanol: A Kinetic Study Bhosale, Rahul R.; Kumar, Anand; AlMomani, Fares; Ghosh, Ujjal; AlNouss, Ahmed; Scheffe, Jonathan; Gupta, Ram B., Industrial & Engineering Chemistry Research 2016, 55(18), 5238-5246.

2016

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Boric Acid Production from Colemanite Together with ex Situ CO2 Sequestration Gonen, Mehmet; Nyankson, Emmanuel; Gupta, Ram B., Industrial & Engineering Chemistry Research 2016, 55(17), 5116-5124.

2016

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Interfacially Active Hydroxylated Soybean Lecithin Dispersant for Crude Oil Spill Remediation, Nyankson, Emmanuel; Demir, Muslum; Gonen, Mehmet; Gupta, Ram B., ACS Sustainable Chemistry & Engineering 2016, 4(4), 2056-2067.

2016

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Catalytic Upgrading of Methane to Higher Hydrocarbons in a Nonoxidative Chemical Conversion Nahreen, Shaima; Praserthdam, Supareak; Perez Beltran, Saul; Balbuena, Perla B.; Adhikari, Sushil; Gupta, Ram B., Energy & Fuels 2016, 30(4), 2584-2593.

2016

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Advancements in Crude Oil Spill Remediation Research After the Deepwater Horizon Oil Spill Nyankson, Emmanuel; Rodene, Dylan; Gupta, Ram B., Water, Air, & Soil Pollution 2016, 227(1), 1-22.

2016

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Interfacial adsorption and surfactant release characteristics of magnetically functionalized halloysite nanotubes for responsive emulsions Owoseni Olasehinde; Zhang Yueheng; Nyankson Emmanuel; Gupta Ram B; Adams Daniel J; Spinu Leonard; He Jibao; McPherson Gary L; Bose Arijit; John Vijay T, Journal of colloid and interface science 2016, 463, 288-98.

2016

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Graphitic Biocarbon from Metal-Catalyzed Hydrothermal Carbonization of Lignin, Demir Muslum; Kahveci, Zafer; Aksoy, Burak; Palapati, Naveen K. R.; Subramanian, Arunkumar; Cullinan, Harry T.; El-Kaderi, Hani M.; Harris, Charles T.; Gupta, Ram B., Industrial & Engineering Chemistry Research 2015, 54(43), 10731-10739.

2015

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Surfactant-Loaded Halloysite Clay Nanotube Dispersants for Crude Oil Spill Remediation Nyankson, Emmanuel; Olasehinde, Owoseni; John, Vijay T.; Gupta, Ram B., Industrial & Engineering Chemistry Research 2015, 54(38), 9328-9341.

2015

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Soybean Lecithin as a Dispersant for Crude Oil Spills Nyankson, Emmanuel; DeCuir, Matthew J.; Gupta, Ram B., ACS Sustainable Chemistry & Engineering 2015, 3(5), 920-931.

2015

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Release of Surfactant Cargo from Interfacially-Active Halloysite Clay Nanotubes for Oil Spill Remediation Owoseni, Olasehinde; Nyankson, Emmanuel; Zhang, Yueheng; Adams, Samantha J.; He, Jibao; McPherson, Gary L.; Bose, Arijit; Gupta, Ram B.; John, Vijay T., Langmuir 2014, 30(45), 13533-13541.

2014

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A Comparison of the Effectiveness of Solid and Solubilized Dioctyl Sodium Sulfosuccinate (DOSS) on Oil Dispersion Using the Baffled Flask Test, for Crude Oil Spill Applications Nyankson, Emmanuel; Ober, Courtney A.; DeCuir, Matthew J.; Gupta, Ram B., Industrial & Engineering Chemistry Research 2014, 53, 11862-11872.

2014

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Nanotechnology in Solar and Biofuels ACS Sustainable Chemistry & Engineering 2013, 1(7), 779-797.

2013

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Deoxy-liquefaction of switchgrass in supercritical water with calcium formate as an in-situ hydrogen donor Ramsurn, Hema; Gupta, Ram B., Bioresource Technology 2013, 143, 575–583.

2013

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Special issue-10th International Symposium on Supercritical Fluids King, Jerry W.; Gupta, Ram B.; Hutchenson, Keith W.; McHugh, Mark A.; Temelli, Feral, Journal of Supercritical Fluids 2013, 79, 1.

2013

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Conversion of the Acetone-Butanol-Ethanol (ABE) Mixture to Hydrocarbons by Catalytic Dehydration Nahreen, Shaima; Gupta, Ram B., Energy & Fuels 2013, 27(4), 2116-2125.

2013

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Formation of itraconazole/L-malic acid cocrystals by gas antisolvent cocrystallization Ober, Courtney A.; Montgomery, Stephen E.; Gupta, Ram B., Powder Technology 2013, 236, 122-131.

2013

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Preparation of rifampicin/lactose microparticle composites by a supercritical antisolvent-drug excipient mixing technique for inhalation delivery Ober, Courtney A.; Kalombo, Lonji; Swai, Hulda; Gupta, Ram B., Powder Technology 2013, 236, 132-138.

2013

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Formation of Itraconazole-Succinic Acid Cocrystals by Gas Antisolvent Cocrystallization Ober, Courtney A.; Gupta, Ram B., AAPS PharmSciTech (2012), 13(4), 1396-1406.

2012

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Catalytic pyrolysis of green algae for hydrocarbon production using H+ZSM-5 catalyst Suchithra Thangalazhy-Gopakumar, Sushil Adhikari, Shyamsundar Ayalur Chattanathan, Ram B. Gupta, Bioresource Technology 2012 118, 150-157.

2012

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Catalytic Pyrolysis of Biomass over H+ZSM-5 under Hydrogen Pressure Thangalazhy-Gopakumar, Suchithra; Adhikari, Sushil; Gupta, Ram B., Energy & Fuels 2012 26(8), 5300-5306.

2012

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pH Control of Ionic Liquids with Carbon Dioxide and Water: 1-Ethyl-3-methylimidazolium Acetate Ober, C.A., Gupta, R.B., Ind. Eng. Chem. Res. 2012 51 (6), 2505-2820.

2012

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Production of Biocrude from Biomass by Acidic Subcritical Water Followed by Alkaline Supercritical Water Two-Step Liquefaction Ramsurn, H., Gupta, R.B., Energy & Fuels 2012 26 (4), 2365-2375.

2012

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Preparation of thalidomide nano-flakes by supercritical antisolvent with enhanced mass transfer Jin, H., Hemingway, M., Gupta, R.B.; Xia, F., Zhao, Y., Particuology 2012 10 (1), 17-23.

2012

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Nanoparticle Technology for Drug Delivery Ober, C.A., Gupta, R.B., Ide@s CONCYTEG 2011 6 (72), 719-731.

2011

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Production of hydrocarbon fuels from biomass using catalytic pyrolysis under helium and hydrogen environments Thangalazhy-Gopakumar, S., Adhikari, S., Gupta, R.B., Tu, M., Taylor, S., Bioresource Technology 2011 102 (12), 6742-6749.

2011

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Single-step preparation and deagglomeration of itraconazole microflakes by supercritical antisolvent method for dissolution enhancement Sathigari, S. K., Ober, C. A., Sanganwar, G.P., Gupta, R.B.; Babu, R.J., Journal of Pharmaceutical Sciences 2011 100 (7), 2952-2965.

2011

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30. Enhancement of Biochar Gasification in Alkali Hydrothermal Medium by Passivation of Inorganic Components Using Ca(OH)2 Ramsurn, H.,Kumar, S.,Gupta, R.B., Energy & Fuels 2011 25 (5), 2389-2398.

2011

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31. Hydrogen production from catalytic gasification of switchgrass biocrude in supercritical water Byrd, A.J., Kumar, S., Kong, L., Ramsurn, H., Gupta, R.B., International Journal of Hydrogen Energy 2011 36 (5), 3426-3433.

2011

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Influence of Pyrolysis Operating Conditions on Bio-Oil Components: A Microscale Study in a Pyroprobe Thangalazhy-Gopakumar, S., Adhikari, S., Gupta, R.B., Fernando, S.D., Energy & Fuels 2011 25 (3), 1191–1199.

2011

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Hydrothermal pretreatment of switchgrass and corn stover for production of ethanol and carbon microspheres Kumar, S., Kothari, U., Kong, L., Lee, Y. Y., Gupta, R.B., Biomass and Bioenergy 2011 35 (2), 956-968.

2011

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Hydrogel Nanopowder Production by Inverse-Miniemulsion Polymerization and Supercritical Drying Hemingway, M.G., Gupta, R.B., Elton, D.J., Industrial & Engineering Chemistry Research 2010 49 (20), 10094-10099.

2010

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Physiochemical properties of bio-oil produced at various temperatures from pine wood using an auger reactor Thangalazhy-Gopakumar, S., Adhikari, S., Ravindran, H., Gupta, R.B., Fasina, O., Tu, M., Fernando, Sandun D., Bioresource Technology 2010 101 (21), 8389-8395.

2010

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Stability of cerium-modified .gamma.-alumina catalyst support in supercritical water Byrd, A.J., Gupta, R.B., Applied Catalysis, A: General 2010 381 (1-2), 177-182.

2010

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Simultaneous production and co-mixing of microparticles of nevirapine with excipients by supercritical antisolvent method for dissolution enhancement Sanganwar, G.P., Sathigari, S., Babu, R. J., Gupta, R.B., European Journal of Pharmaceutical Sciences 2010 39 (1-3), 164-174.

2010

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Cellulose pretreatment in subcritical water: Effect of temperature on molecular structure and enzymatic reactivity Kumar, S., Gupta, R., Lee, Y. Y., Gupta, R.B., Bioresource Technology 2010 101 (4), 1337-1347.

2010

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