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Professor Roslyn Bill discusses her research into brain cell membranes with Dr Matt Derry Serious brain injuries and dementia are affected by the flow of water through a protein called aquaporin-4 in brain cell membranes Aquaporins are responsible for clearing the build-up of waste products in brain cells in a process Professor Bill likens to a ‘dishwasher for your brain’. Professor Roslyn Bill, co-founder of Aston Institute for Membrane Excellence (AIME), joins Dr Matt Derry to discuss her research into brain cell membranes in the latest Aston Originals podcast. Water moves in and out of brain cells through tiny protein channels in the cell membrane called aquaporins. One in particular, aquaporin-4, is the focus of Professor Bill’s research. In 2020, she was lead author on a paper published in prestigious journal Cell on how the channels open and close and how this can be controlled. Uncontrolled water entry into brain cells can occur after head trauma, causing swelling which leads to severe brain injuries of the type suffered by racing driver Michael Schumacher after a skiing accident. Finding drugs to control this water movement could lead to treatments to prevent brain swelling in the first place. This research into brain swelling and the contribution of aquaporins led Professor Bill to research into Alzheimer’s, a common form of dementia, which is also related to the action of aquaporins. Alzheimer’s is caused by a build-up of waste products in brain cells. In a process Professor Bill likened to a ‘dishwasher for your brain’, aquaporins are responsible for clearing this waste as we sleep. Professor Bill was selected for an Advanced Grant by the European Research Council (ERC) in 2023, which is being funded by UK Research and Innovation (UKRI). The funded project will further investigate the process, and whether it might be possible to develop a drug to boost the ‘brain dishwasher’, which could be taken to slow or even prevent cognitive decline due to ageing. Bringing together this biological research with the polymer research of AIME, chemists like Dr Derry will help in the drug development and could also lead to totally different applications. Professor Bill said in the podcast to Dr Derry: “We can take the knowledge that we have of how these proteins work in cells and try and apply them to interesting applications in biotechnology. And this is where the sort of work that you (Dr Derry) do comes in, where you can develop plastic membranes, polymer membranes, and then take learning from the biology and try and make really, really good ways of purifying water, for example.” For more information about AIME, visit the webpage. The website also includes links to the previous AIME podcast and details about open positions.

The countdown is on for the total solar eclipse on April 8 and Adam Frank, professor of astrophysics, science commentator, and popular author, is available to comment on: Earth's eclipses are the result of a cosmic accident! No other world has such a relatively large moon. Our Moon is the result of a titanic collision with a Mars sized planet more than 4 billion years ago. Earth is likely the only planet that experiences a solar corona/ring of fire during a total eclipse. That's because the size of the moon and the size of the sun appear to be roughly the same from Earth. The moon is slowly drifting away from the Earth so the kind of eclipses we experience are also an accident in time. Were not possible before, won't be possible later. Eclipses must have been terrifying for early humans. Learning to predict them helped establish the possibility for science. Today eclipses can be a way to help people understand and appreciate the sciences. The science surrounding the eclipse is the same science that gives us vaccines and helps us understand climate change (science is science). The "devil comet" may be visible during the eclipse. The comet passes by Earth every 71 years. The comet, which glows green and red, gets its nickname from outbursts that take on the shape of horns. Adam Frank is a frequent on-air commentator for live interviews and segments in national media outlets. He also regularly contributes to written publications, including The Washington Post, The Atlantic, The New York Times, and Scientific American. In 2021 he received the Carl Sagan Medal, which recognizes and honors outstanding communication by an active planetary scientist to the general public. It is awarded to scientists whose efforts have significantly contributed to a public understanding of, and enthusiasm for, planetary science. His most recent book is The Little Book of Aliens (Harper Collins, 2023).

• Leading scientist wins €2.2 million ERC Advanced Grant • The five-year project will explore early dementia interventions through understanding how an aquaporin water channel regulates glymphatic clearance • ERC Advanced Grant funding is amongst the most prestigious and competitive of the EU funding schemes. A world leading scientist in the College of Health and Life Sciences at Aston University has been awarded a €2.2 million ERC Advanced Grant to understand how the movement of a protein known as aquaporin-4 in the brain can help slow cognitive decline. The FORTIFY project, which will run for five years, is led by Professor Roslyn Bill in the School of Biosciences. She will apply her discovery of the movement of aquaporin-4 to understand how the cleaning mechanism in the brain works during sleep. The research will focus on how aquaporin-4 controls the glymphatic system, which is the mechanism that allows us to clear waste products from our brains while we sleep. Her hypothesis is that the movement of aquaporin-4 in the brain changes the effectiveness of this cleansing mechanism - which lessens as people age. A greater understanding of this process could lead to an early intervention treatment that could slow the onset of dementia, such as Alzheimer’s and Parkinson’s Diseases. ERC Advanced Grant funding is amongst the most prestigious and competitive of the EU funding schemes, providing researchers with the opportunity to pursue ambitious, curiosity-driven projects that could lead to major scientific breakthroughs. Professor Bill said: “Every three seconds someone in the world develops dementia and there is no cure. I want to stop that from happening. By understanding the molecular mechanisms of brain waste clearance, we have an opportunity to develop medicines that can slow the onset of dementia, very much in the same way that statins are prescribed to control heart disease”. Roslyn Bill discovered that the water channel protein aquaporin-4 increases the permeability of brain cells to water after a brain or spinal cord injury. Around 60 million people a year suffer such injuries following falls or accidents. For example, after a skiing accident in the French Alps in 2013, Michael Schumacher suffered a severe head injury. He was placed in a medically induced coma and underwent several surgeries to treat his injuries. Until now doctors have only been able to manage the symptoms of brain injury (swelling on the brain) through interventions that may require surgery. Professor Bill and her team are due to start clinical trials in summer 2023, to test a method to stop the swelling from happening in its tracks, building on her discoveries. Roslyn’s new ERC-funded project, FORTIFY, will focus on how aquaporin-4 controls fluid flow in the healthy, uninjured brain. In this round of Advanced Grants, the European Research Council (ERC) is awarding €544 million to 218 outstanding research leaders across Europe, as part of the Horizon Europe programme. The grants will support cutting edge research in a wide range of fields, from medicine and physics to social sciences and humanities. The grant is awarded to established, leading researchers with a proven track-record of significant research achievements over the past decade. The funding will enable the researchers to explore their most innovative and ambitious ideas. Mariya Gabriel, European Commissioner for Innovation, Research, Culture, Education and Youth, said: “ERC grants are a top recognition and a significant commitment from our best researchers. The €544 million funding puts our 218 research leaders, together with their teams of postdoctoral fellows, PhD students and research staff, in pole position to push back the boundaries of our knowledge, break new ground and build foundations for future growth and prosperity in Europe” Maria Leptin, ERC President, added: "These new ERC Advanced Grantees are a testament to the outstanding quality of research carried out across Europe. I am especially pleased to see such a high number of female researchers in this competition and that they are increasingly successful in securing funding. “We look forward to seeing the results of the new projects in the years to come, with many likely to lead to breakthroughs and new advances.”

Bowel or fecal incontinence, according to the Mayo Clinic, “is the inability to control bowel movements, causing stool (feces) to leak unexpectedly from the rectum. Also called bowel incontinence, fecal incontinence ranges from an occasional leakage of stool while passing gas to a complete loss of bowel control. Common causes of fecal incontinence include diarrhea, constipation, and muscle or nerve damage. The muscle or nerve damage may be associated with aging or with giving birth.” Dr. Satish Rao is a seasoned gastroenterologist and an expert in digestive health, particularly the brain-gut connection. Rao, a professor of medicine at the Medical College of Georgia at Augusta University, recently offered a Q&A on the topic of fecal incontinence with the journal Gastroenterology & Hepatology. What is the prevalence of fecal incontinence in the adult population? Surveys have indicated a prevalence of approximately 9% to 10% in the United States. A recent study reported a 14% prevalence, although this study was Internet-based and, thus, may not have included many elderly patients, as they may not be as computer-savvy as younger patients. It is safe to say that one in seven Americans currently suffers from fecal incontinence. Prevalence appears to be equal in men and women, although women outnumber men almost three to one when it comes to gastroenterology clinic visits and health care-seeking. Men may be too embarrassed to bring the issue of fecal incontinence to the attention of a physician, but when asked about it, they will admit and discuss it. Also, extracting information from a patient about fecal incontinence depends on how the question is asked. Asking patients whether they have daily leakage vs whether they ever have had leakage or have had leakage in the past month will elicit different responses that a clinician may interpret differently. It is important to remember that leakage is not a physiologic event that a healthy adult should have at any time, even once a month or once a year. Not having the capacity to control bowel evacuation or having leakage unaware of its occurrence signals an abnormality. What are notable risk factors for fecal incontinence? In women, pregnancy can be a risk factor, particularly if giving birth involves pelvic tissue damage, such as injury inflicted by forceps use or the unfortunate occurrence of a significant tear. Neurologic or back injuries are other common risk factors. Also, chronic diarrhea can progress to fecal incontinence owing to severe irritation of the rectum or irritants in stool. Further, any condition that changes the ability of rectal capacity can result in fecal incontinence. These circumstances can include surgery or radiation to the rectal area. Hear from a patient and learn more about Rao's research using magnetic stimulation to treat fecal incontinence. What treatment modalities are currently available? Simple, conservative treatment consists of educating patients about fecal incontinence and instructing them to avoid precipitating events. For example, although many people love to have a meal followed by a cup of coffee and a walk, such a sequence of activities is ill-advised for an incontinent patient: the meal provokes a gastric-colonic response, coffee is a powerful colonic stimulant, and exercise also stimulates motility. This triad creates the perfect storm for a stool leakage or accident while the patient is out on the after-dinner walk. Antidiarrheal therapies can be very effective but only in approximately 15% to 20% of patients. Another treatment is biofeedback, which can correct muscle weakness using behavioral techniques. Biofeedback provides resolution in approximately 50% to 70% of patients. The traditional model of office-based biofeedback requires that the patient make 6 or even up to 10 visits to a specialty clinic. This may mean that some patients must drive very long distances to an appropriate care facility that is staffed with trained personnel or physical therapists. This scenario presents a significant challenge for many patients, which is increasingly being recognized by health care professionals and researchers. Good devices for home-based biofeedback have been scarce; however, such a device was recently approved by the US Food and Drug Administration. The research center at Augusta University has tested it in a clinical trial setting and found it to be quite effective as a home biofeedback treatment. Dextranomer is another treatment modality. It involves injection of small beads of dextran polymers into the anorectal region. The beads form a protective cuff or a buffer to stop stool leakage. Another treatment modality is sacral nerve stimulation using the Medtronic InterStim system. The patient is outfitted with a pacemaker-like device with wires that continuously stimulate the sacral nerves that control stool events. In the case of a torn muscle, suturing the torn ends to reduce the size of the anorectal opening is usually useful for women postpartum, although the effect may not be sustained in the long term. What emerging treatments and research should clinicians be aware of? One emerging treatment developed at Augusta University’s Clinical Research Center is called translumbosacral neuromodulation therapy (TNT). TNT is similar to TAMS and involves the fecal delivery of magnetic energy through an insulated coil to the lumbosacral nerves that regulate anorectal function. The pulses generated are of the same strength as those of magnetic resonance imaging. The team at Augusta University’s research center has shown that TNT mechanistically improves nerve function and substantively improves stool leakage. A sham-controlled study and long-term study are currently underway at Augusta University and Harvard University’s Massachusetts General Hospital. These studies are being sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases. A multicenter study sponsored by the National Institutes of Health that the team at Augusta University also is involved with is the FIT (Fecal Incontinence Treatment) trial. This randomized study compares biofeedback with dextranomer injection. Also, as mentioned, tools are becoming available for home biofeedback that should allow many more affected patients to receive treatment because they can do so in the comfort of their own home. The research center at Augusta University is working on a novel home biofeedback protocol for the treatment of constipation and fecal incontinence. Thus, novel noninvasive tools are emerging for fecal incontinence. The repertoire of current and emerging tools holds the promise of improved outcomes for patients with fecal incontinence. Rao is also the founder of the Augusta University Digestive Health Center. He is available to speak to media regarding any aspect of digestive health -- simply click on his icon now to arrange an interview today.

Many of us think of ADHD (attention deficit hyperactivity disorder) as a childhood condition – which is typically when it’s diagnosed. But a growing number of people are sharing their experiences of being diagnosed with ADHD in adulthood. Social media has even played a role in this, with reports of people going to see their doctor after first learning about symptoms on TikTok. In fact, around 2.5% of adults are thought to live with ADHD – including us. Yet despite this growing awareness, many adults continue to struggle to get a diagnosis. ADHD is a genetic neurodevelopmental disorder, in which the brain grows differently, lacking action from specific chemicals involved in pleasure and reward. This means ADHD brains often search for ways to stimulate these chemicals, which is why people can experience inattentiveness, hyperactivity and impulsivity. Common traits of ADHD include: Not following through on longer tasks (or not starting them) Getting distracted by other tasks or thoughts Seeking out risk or activities that provide immediate reward Restlessness (either outwardly or internally) Interrupting other people (without wanting to) Symptoms are similar for both adults and children, although elements of them differ or change as we age. For example, inattention is the most persistent symptom in adults. ADHD can be debilitating and is associated with higher likelihood of lower quality of life, substance use issues, unemployment, accidental injuries, suicide and premature death. In addition, ADHD can cost adults around £18,000 per year because of things like medical care or paying for social support. It’s also commonly associated with a wide range of co-existing conditions in adults. For example, depression is almost three times more prevalent in adults with ADHD. And nearly half of all adults with ADHD also have bipolar spectrum disorder. Around 70% of adults with ADHD also experience emotional dysregulation, which can make it more difficult to control emotional responses. It’s also thought that almost all adults with ADHD have rejection sensitive dysphoria, a condition where perceived rejection or criticism can cause extreme emotional sensitivity or pain. On top of this, adults with ADHD may have poor working memory – such as being unable to remember a simple shopping list – and “time blindness” (the inability to perceive time). Some may also have oppositional defiant disorder, which means they often react poorly to perceived orders or rules. While none of these co-existing conditions are used to diagnose ADHD, they can make ADHD feel all the more difficult to live with. Being diagnosed Getting an ADHD diagnosis as an adult in the UK is notoriously difficult – with reports of some people waiting up to five years. Waiting for a diagnosis is common for adults with ADHD. Roman Kosolapov/ Shutterstock This is because you can only be diagnosed by a specialist psychiatrist. But even with a referral to a specialist, a person has to show clear evidence of almost all ADHD traits, having had these traits since childhood, and that they’re having a serious affect on their life – such as causing issues with work, education, or maintaining relationships. For us, our experiences of being diagnosed with ADHD aren’t all that different from what other adults have gone through. Like many people I (Alex) was only diagnosed with ADHD “by accident” after being referred to an NHS psychiatrist to get help with (what I now know to be) alcohol self-medication. Because of my ADHD, my brain demands quite extreme inputs most of the time. Ironically, I’ve published scientific papers on ADHD and – probably due to a classic ADHD lack of self-awareness – it didn’t cross my mind that I could have it. The “label” has since helped me move away from feeling broken toward an understanding of my behaviour. My main challenges remain prioritising tasks based on importance (instead of excitement) and quite extreme anti-authority behaviour (sometimes called oppositional defiance). I am also a terrible spectator, struggling to attend conference talks or sit still at the theatre – it can feel like physical pain. On the other hand, I (James) was diagnosed pretty quickly because I used a private clinic – though there was still a long wait for medication. Yet I’d known for five years before this that I probably had ADHD, but coped with it well until the pandemic. The added pressure of isolation and increased workload impacted my mental health, so I sought a diagnosis. Now diagnosed and medicated, life is getting easier to cope with – although there are still many challenges every day. I frequently get anxiety about the silliest things, like talking to a friend, but appearing on television is fine. On a daily basis I forget many simple things, such as where I left my keys, or that I am running a bath. I struggle immensely with controlling my emotions and with rejection especially. For example, when no one responded to a joke I made about my ADHD on a senior management messaging group I was tempted to quit my job. I am utterly unable to pay full attention in meetings or seminars and cannot control my impulse purchasing. While there’s a growing recognition of ADHD in adults, many people still live with it undiagnosed for any number of reasons – sometimes even because they’re unaware that what they experience is actually different from other people. Understanding the condition in adults, taking it more seriously as a disorder, raising awareness of it, and investing in services to improve diagnosis times are key. Diagnosis opens the door to treatment, which can have a marked impact on living with the disorder – such as improving self-esteem, productivity and quality of life. This article was co-written by Dr James Brown (Aston University) and Dr Alex Connor (University of Birmingham)

Welcoming 2021: The Year of Resiliency
Happy New Year to all — may 2021 be a better and brighter year for everyone. It has been just over a year since I came to Japan Society as President and CEO, with a mandate to take the Society into the future while preserving its 113-year-old mission of building bridges between the U.S. and Japan. The pandemic has accelerated the pace of change for everyone, globally, nationally, locally, and within our own workplaces and households. Change is hard, but it is also necessary. In a recent email, my friend Parag Khanna wrote, “Our global system evolves the way humanity does, not through grand design or random accident but by adaptation to changing realities. The faster we react to an accelerating world, the better our chances of shaping the future to our benefit.” I’d like to speak to Parag’s point personally rather than geopolitically. The experience of leading a New York nonprofit during this time — an institution that is both deeply and historically embedded in onsite programming and tradition — has both clarified and strengthened my vision for Japan Society’s future. Bending Adversity If 2020 has forced us to prioritize, 2021 will be the year of resiliency. 2021 represents the year of the Ox in Japan, where the ox is considered an industrious, cautious, and faithful friend that is always glad to offer help. After the 2020 we’ve all had, we could use more faithful friends like the ox in 2021. We are looking toward 2021 as a year in which we as a society ultimately overcome COVID-19 through the efforts of scientists, frontline workers, and governments around the globe. We hope to see the world come together in a big way for the first time at the rescheduled Summer Olympics in Tokyo. In some ways, we have already seen the future in Japan and in Asia more broadly, with its successful response to the COVID pandemic. Japan also represents a recent example of how to bend adversity and bounce back, as it did from the Great East Japan Earthquake, tsunami and nuclear disaster of 3/11/2011. The entire country came together in solidarity to support the affected Tohoku region, including concrete measures such as limiting electricity usage at a national level to avoid rolling regional blackouts. A decade on, Japan still remembers, with the Olympic flame set to depart from Fukushima Prefecture in the torch relay that will cross the country before arriving in Tokyo for the Opening Ceremony. Out of Crisis: Opportunity Optimism and positivity are necessary to move forward. I’m optimistic not because I’m naïve about the challenges ahead as we continue to navigate these wild currents, but I am confident that we will find safe passage because of what we have learned collectively and adapted to over the past months. Japan Society’s Language Center had a record year in 2020 despite the pandemic as our teachers reached beyond our physical classrooms to virtual ones; more people joined us than ever before for our first-ever digital JAPAN CUTS, the largest festival of Japanese cinema in North America. We have opened possibilities far beyond our physical building, the original Japan House, designed by Japanese modernist architect Junzo Yoshimura 50 years ago, and named New York City’s youngest landmark in 2011. In crisis comes opportunity, and from opportunity come the possibilities for our collective future. While we are hurting without our physical programs and admissions revenue, we’ve literally been able to connect across the world, and even beyond — from Japanese astronaut Soichi Noguchi, who is currently on the International Space Station, to countless leading voices in Japan such as Olympics Director Nomura Mansai — to create unique experiences for our members. In this time, I return to the Japanese concept of kaizen (改善), continual self-improvement and change for the better. Regardless of the next challenges on the horizon, I’m committed to ensuring that we continuously improve and adapt in this spirit. I believe that our mission has never been more critical than in 2021 as we strengthen U.S.-Japan relations with new administrations in both capitals and seek opportunities to engage, explore, and educate our societies about our collective resiliency as we welcome the new year. Joshua Walker (@drjwalk) is president and CEO of Japan Society. Follow @japansociety. The views expressed in this article are the writer’s own.

MEDIA RELEASE: CAA supports Ontario government's focus to reform the towing industry
CAA South Central Ontario supports the Ontario government’s move to assemble a task force to review and reform the towing industry. Changes to the towing industry is something that CAA has been advocating for over a decade and the task force announced today is a strong step in the right direction. “There are a number of measures that will go a long way to restore motorist confidence and keep our roads safe across the province,” says Teresa Di Felice, assistant vice-president of government and community relations. “We would like to see a tow truck licensing system, clearer rules around consumer protection and the establishment of a body to oversee the industry.” CAA has been actively working with stakeholders and government officials towards provincial oversight of the towing industry. Provincial oversight would provide consistent levels of training for operators, ensure the vitality of an essential service on Ontario roads and established penalties for those that do not follow the rules. It would also ensure consumers would have certainty when it comes to their towing services, regardless of when or where they require support. CAA is also advocating for the necessary regulation that would implement criminal background checks, discourage racing to accident scenes, charging consumers sky high towing bills, and fraud. “For years now the towing industry has been plagued with unscrupulous drivers who take advantage of consumers in their most stressful times of need. Regulating the industry would enhance consumer protection for motorists,” adds Di Felice.

The link between veterans coming home and racial violence in America. Our expert can explain.
There is a long history of white supremacist and white-power ideology developing out of the wars the United States has fought. In Bring the War Home: The White Power Movement and Paramilitary America (Harvard University Press, 2018), Kathleen Belew shows that, beginning in the 1970s, a small but committed number of Vietnam War veterans took the racist understanding of the Vietnamese and Asians more broadly that the U.S. military taught them and became instrumental in building the current white-power movement. These vets often did not initially know each other, but they eventually built a wide variety of organizations: the White Aryan Resistance, the latest, post-Civil Rights Era iteration of the Ku Klux Klan, various Christian Identity and white skinhead organizations, and the militia movement of the 1980s and 1990s. In his forthcoming book, Guarding the Empire: Soldier Strikebreakers on the Long Road to the Ludlow Massacre, Otterbein’s Dr. Anthony DeStefanis has found that the men who fought the Plains Indians in the late nineteenth century and who served in Cuba and the Philippines during the Spanish-American-Filipino War (1898-1902) came to understand Native Americans, Cubans, and Filipinos as formidable but racially inferior enemies. When these same men joined the National Guards in states across the country and were called out on strike duty during the late nineteenth and early twentieth century, they took what they learned on the Plains and overseas to create a racist rationale for breaking the labor strikes of a working class that was increasingly made up of southern and eastern European, Mexican, and Asian immigrants. Many of these same men also joined the Second Ku Klux Klan that emerged in the late 1910s and became a nationwide organization by expanding the targets of its hatred beyond African Americans to include Jews, Catholics, and immigrants. Racism is a many-headed hydra with multiple roots in experience at home and abroad. Some white southerners who were central in the project of creating and maintaining Jim Crow white supremacy were Confederate military veterans and it is clear that wars across the twentieth century – from Cuba and the Philippines to Vietnam – pushed some veterans into the white- power movement. Today, we know that white-power organizations concentrate on recruiting military veterans and we have seen a spike in support for these organizations among current members of the military. It’s no accident that some of these active troops and veterans served in the Iraq and Afghan Wars, where they faced a Muslim enemy with unfamiliar social and cultural practices, and who did not welcome the U.S. military presence with open arms. Clearly, we must reckon with what our wars overseas have brought back to the United States. If you are a reporter covering this topic – let the experts from Otterbein University help. Dr. Anthony DeStefanis is an associate professor of history at Otterbein University. He specializes in modern U.S. history with an emphasis on labor and the working class and immigration, race, and ethnicity. Dr. DeStefanis is available to speak with media regarding the history of racial violence in America – simply click on his icon to arrange an interview.

Anyone can experience PTSD – let our experts help answer questions about PTSD Awareness Month
June is PTSD Awareness Month. It’s not just an affliction that affects soldiers and first responders – it can also impact anyone who may have been in an accident, experienced abuse or witnessed a tragedy. According to the U.S. Department of Veterans Affairs, “Post-traumatic stress disorder (PTSD) can occur after you have been through a trauma. A trauma is a shocking and dangerous event that you see or that happens to you. During this type of event, you think that your life or others' lives are in danger.” According to Veteran’s Affairs: About 7 or 8 out of every 100 people (or 7-8% of the population) will have PTSD at some point in their lives. About 8 million adults have PTSD during a given year. This is only a small portion of those who have gone through a trauma. About 10 of every 100 women (or 10%) develop PTSD sometime in their lives compared with about 4 of every 100 men (or 4%). There is nothing new about PTSD, other than its terminology. In World War 1, it was labeled “shell shock” and many perceived it as a sign of weakness as opposed to an injury. Since then it has been called “combat fatigue” and in the 1970s, “post-Vietnam syndrome.” But what about now? With so many veterans returning from overseas and the public now being more informed of those who may have been afflicted domestically, questions include: Is acceptance of PTSD improving? Does the stigma still stick with those looking to return to their careers? Are there new and innovative ways to treat PTSD and how do they work? As we round out PTSD awareness month, let our experts help with your stories. Dr. Nagy Youssef is an associate professor of psychiatry at Augusta University and is a leading expert in PTSD and suicide prevention who treats civilians, active duty military and veterans. His research focuses on mechanistic and therapeutic innovation for treatment-resistant psychiatric disorders and suicide prevention. Dr. Youssef is also in the early stages of forming a study to better detect genetic markers associated with PTSD and resilience to trauma. Participation in this study is voluntary. Learn how to participate in “Epigenomics Association Study of PTSD and Resilience” at https://www.augusta.edu/research/studies/list.php.

Is Washington playing Russian roulette with airline safety?
The government shutdown that is finally over had some worrying near the end and for good reason. Air traffic controllers, the very professionals who keep planes in the air and at a safe distance from each other had gone for more than four weeks without getting paid. Exhausted, demoralized and depleting ranks were probably the near-perfect storm for an imminent accident or disaster. Luckily, and thankfully, these dedicated professionals rose to the occasion and ensured safety was still the priority. Often, working even while the very equipment and technology they rely on was not being serviced. But as the shutdown takes a break for three weeks and everyone is made whole with back-wages and paychecks – does America need to rethink the potential risks and consequences to having the staff who are essential to safety across the entire country go without pay and benefits during a political dispute? The consequences of a major airline crash are huge economically and in terms of lives lost. So, can the nation’s air traffic controllers be exempt form the impacts of a government shutdown? Who would have been liable if an accident did occur? Are aviation, customs and our nation’s airports not considered essential and therefore worthy of being paid during a shutdown? And how close did we come to a disaster? While we wait and watch for a solution in Washington over the coming weeks, there are still a lot of questions to be answered, and that’s where the experts from the University of Rochester can help. David M. Primo is the Ani and Mark Gabrellian Professor and an associate professor of political science and business administration at the University of Rochester. He is an expert in airport safety and security and a professor at the University of Rochester in Rochester, New York, and can comment on airline safety and passenger impacts amid airports such as Laguardia International restricting air travel due to the government shutdown. David is available to speak with media regarding the economic effects of the shutdown – simply click on his icon to arrange an interview.