Experts Matter. Find Yours.
Connect for media, speaking, professional opportunities & more.
Hormone Supplementation in Rhesus Monkeys Points to Potential Autism Treatment
For years, Florida Tech’s Catherine Talbot, assistant professor of psychology, has worked to understand the sociality of male rhesus monkeys and how low-social monkeys can serve as a model for humans with autism. Her most recent findings show that replenishing a deficient hormone, vasopressin, helped the monkeys become more social without increasing their aggression – a discovery that could change autism treatment. Currently, the Centers for Disease Control and Prevention report that one in 36 children in the United States is affected by autism spectrum disorder (ASD). That’s an increase from one in 44 children reported in 2018. Two FDA-approved treatments currently exist, Talbot said, but they only address associated symptoms, not the root of ASD. The boost in both prevalence and awareness of the disorder prompts the following question: What is the cause? Some rhesus monkeys are naturally low-social, meaning they demonstrate poor social cognitive skills, while others are highly social. Their individual variation in sociality is comparable to how human sociality varies, ranging from people we consider social butterflies to those who are not interested in social interactions, similar to some people diagnosed with ASD, Talbot said. Her goal has been to understand how variations in biology and behavior influence social cognition. In the recent research paper published in the journal PNAS, “Nebulized vasopressin penetrates CSF [cerebral spinal fluid] and improves social cognition without inducing aggression in a rhesus monkey model of autism,” Talbot and researchers with Stanford, the University of California, Davis and the California National Primate Research Center explored vasopressin, a hormone that is known to contribute to mammalian social behavior, as a potential therapeutic treatment that may ultimately help people with autism better function in society. Previous work from this research group found that vasopressin levels are lower in their low-social rhesus monkey model, as well as in a select group of people with ASD. Previous studies testing vasopressin in rodents found that increased hormone levels caused more aggression. As a result, researchers warned against administering vasopressin as treatment, Talbot said. However, she argued that in those studies, vasopressin induced aggression in contexts where aggression is the socially appropriate response, such as guarding mates in their home territory, so the hormone may promote species-typical behavior. She also noted that the previous studies tested vasopressin in “neurotypical” rodents, as opposed to animals with low-social tendencies. “It may be that individuals with the lowest levels of vasopressin may benefit the most from it – that is the step forward toward precision medicine that we now need to study,” Talbot said. In her latest paper, Talbot and her co-authors tested how low-social monkeys, with low vasopressin levels and high autistic-like trait burden, responded to vasopressin supplementation to make up for their natural deficiency. They administered the hormone through a nebulizer, which the monkeys could opt into. For a few minutes each week, the monkeys voluntarily held their face up to a nebulizer to receive their dose while sipping white grape juice – a favorite among the monkeys, Talbot said. After administering the hormone and verifying that it increased vasopressin levels in the central nervous system, the researchers wanted to see how the monkeys responded to both affiliative and aggressive stimuli by showing them videos depicting these behaviors. They also compared their ability to recognize and remember new objects and faces, which is another important social skill. They found that normally low-social monkeys do not respond to social communication and were better at recognizing and remembering objects compared to faces, similar to some humans diagnosed with ASD. When the monkeys were given vasopressin, they began reciprocating affiliative, pro-social behaviors, but not aggression. It also improved their facial recognition memory, making it equivalent to their recognition memory of objects. In other words, vasopressin “rescued” low-social monkeys’ ability to respond prosocially to others and to remember new faces. The treatment was successful – vasopressin selectively improved the social cognition of these low-social monkeys. “It was really exciting to see this come to fruition after pouring so much work into this project and overcoming so many challenges,” Talbot said of her findings. One of Talbot’s co-authors has already begun translating this work to cohorts of autism patients. She expects more clinical trials to follow. In the immediate future, Talbot is examining how other, more complex social cognitive abilities like theory of mind – the ability to take the perspective of another – may differ in low-social monkeys compared to more social monkeys and how this relates to their underlying biology. Beyond that, Talbot hopes that they can target young monkeys who are “at-risk” of developing social deficits related to autism for vasopressin treatment to see if early intervention might help change their developmental trajectory and eventually translate this therapy to targeted human trials. Catherine F. Talbot is an Assistant Professor in the School of Psychology at Florida Tech and co-director of the Animal Cognitive Research Center at Brevard Zoo. Dr. Talbot joined Florida Tech from the Neuroscience and Behavior Unit at the California National Primate Research Center at the University of California, Davis, where she worked as a postdoc on a collaborative bio-behavioral project examining naturally occurring low-sociability in rhesus monkeys as a model for the core social deficits seen in people with autism spectrum disorder, specifically targeting the underlying mechanisms of social functioning. If you're interested in connecting with Catherine Talbot - simply contact Adam Lowenstein, Director of Media Communications at Florida Institute of Technology at adam@fit.edu to arrange an interview today.
Name: Linxia Gu Title: Professor of biomedical engineering and science, department head Department/college: Department of Biomedical Engineering and Science/College of Engineering and Science Current research funding: $5 million as co-PI of ASCEND General research focus: My research focuses on developing physically based computational models and conducting mechanical testing to investigate how mechanical stimuli influence cell and tissue responses, providing new insights into the interplay between mechanics and biology. Dr. Gu’s research expertise lies in the biomechanics and biomaterials using both computational and experimental methods. The specific application areas include vascular mechanics and indirect traumatic injury to the brain and eye. Her group is particularly interested in developing multi-scale multi-physics models to study and exploit tissue responses and cellular mechanotransduction, and to gain new mechanistic insights into the interplay of mechanics and human body. The multidisciplinary effort has resulted in > 130 journal papers, and $11 million research funding from NIH, NSF, ARO, and NASA. Q: What has you excited about your current research? The opportunity to bridge the gap between mechanics and biology drives my research. By integrating computational models with experimental data, we are uncovering how mechanical forces influence tissue and cellular responses, particularly in the areas of vascular stenting and traumatic injury to the eye and brain. This had the potential to drive breakthroughs in understanding, prevention and treatment. Q: Why is it important to conduct research? Conducting research is vital for addressing pressing societal challenges and advancing our understanding of complex biomedical systems. Linxia Gu is available to speak with media. Contact Adam Lowenstein, Director of Media Communications at Florida Institute of Technology, at adam@fit.edu to arrange an interview today.
Chemical and Life Science Engineering Professor Michael “Pete” Peters, Ph.D., is investigating more efficient ways to manufacture biologic pharmaceuticals using a radial flow bioreactor he developed. With applications in vaccines and other personalized therapeutic treatments, biologics are versatile. Their genetic base can be manipulated to create a variety of effects from fighting infections by stimulating an immune response to weight loss by producing a specific hormone in the body. Ozempic, Wegovy and Victoza are some of the brand names for Glucagon-Like Peptide-1 (GLP-1) receptor agonists used to treat diabetes. These drugs mimic the GLP-1 peptide, a hormone naturally produced in the body that regulates appetite, hunger and blood sugar. “I have a lot of experience with helical peptides like GLP-1 from my work with COVID therapeutics,” says Peters. “When it was discovered that these biologic pharmaceuticals can help with weight loss, demand spiked. These drug types were designed for people with type-2 diabetes and those diabetic patients couldn’t get their GLP-1 treatments. We wanted to find a way for manufacturers to scale up production to meet demand, especially now that further study of GLP-1 has revealed other applications for the drug, like smoking cessation.” Continuous Manufacturing of Biologic Pharmaceuticals Pharmaceuticals come in two basic forms: small-molecule and biologic. Small-molecule medicines are synthetically produced via chemical reactions while biologics are produced from microorganisms. Both types of medications are traditionally produced in a batch process, where base materials are fed into a staged system that produces “batches” of the small-molecule or biologic medication. This process is similar to a chef baking a single cake. Once these materials are exhausted, the batch is complete and the entire system needs to be reset before the next batch begins. “ The batch process can be cumbersome,” says Peters. “Shutting the whole process down and starting it up costs time and money. And if you want a second batch, you have to go through the entire process again after sterilization. Scaling the manufacturing process up is another problem because doubling the system size doesn’t equate to doubling the product. In engineering, that’s called nonlinear phenomena.” Continuous manufacturing improves efficiency and scalability by creating a system where production is ongoing over time rather than staged. These manufacturing techniques can lead to “end-to-end” continuous manufacturing, which is ideal for producing high-demand biologic pharmaceuticals like Ozempic, Wegovy and Victoza. Virginia Commonwealth University’s Medicines for All Institute is also focused on these production innovations. Peters’ continuous manufacturing system for biologics is called a radial flow bioreactor. A disk containing the microorganisms used for production sits on a fixture with a tube coming up through the center of the disk. As the transport fluid comes up the tube, the laminar flow created by its exiting the tube spreads it evenly and continuously over the disk. The interaction between the transport medium coming up the tube and the microorganisms on the disk creates the biological pharmaceutical, which is then taken away by the flow of the transport medium for continuous collection. Flowing the transport medium liquid over a disc coated with biologic-producing microorganisms allows the radial flow bioreactor to continuously produce biologic pharmaceuticals. “There are many advantages to a radial flow bioreactor,” says Peters. “It takes minutes to switch out the disk with the biologic-producing microorganisms. While continuously producing your biologic pharmaceutical, a manufacturer could have another disk in an incubator. Once the microorganisms in the incubator have grown to completely cover the disk, flow of the transport medium liquid to the radial flow bioreactor is shut off. The disk is replaced and then the transport medium flow resumes. That’s minutes for a production changeover instead of the many hours it takes to reset a system in the batch flow process.” The Building Blocks of Biologic Pharmaceuticals Biologic pharmaceuticals are natural molecules created by genetically manipulating microorganisms, like bacteria or mammalian cells. The technology involves designing and inserting a DNA plasmid that carries genetic instructions to the cells. This genetic code is a nucleotide sequence used by the cell to create proteins capable of performing a diverse range of functions within the body. Like musical notes, each nucleotide represents specific genetic information. The arrangement of these sequences, like notes in a song, changes what the cell is instructed to do. In the same way notes can be arranged to create different musical compositions, nucleotide sequences can completely alter a cell’s behavior. Microorganisms transcribe the inserted DNA into a much smaller, mRNA coded molecule. Then the mRNA molecule has its nucleotide code translated into a chain of amino acids, forming a polypeptide that eventually folds into a protein that can act within the body. “One of the disadvantages of biologic design is the wide range of molecular conformations biological molecules can adopt,” says Peters. “Small-molecule medications, on the other hand, are typically more rigid, but difficult to design via first-principle engineering methods. A lot of my focus has been on helical peptides, like GLP-1, that are a programmable biologic pharmaceutical designed from first principles and have the stability of a small-molecule.” The stability Peters describes comes from the helical peptide’s structure, an alpha helix where the amino acid chain coils into a spiral that twists clockwise. Hydrogen bonds that occur between the peptide’s backbone creates a repeating pattern that pulls the helix tightly together to resist conformational changes. “It’s why we used it in our COVID therapeutic and makes it an excellent candidate for GLP-1 continuous production because of its relative stability,” says Peters. Programming The Cell Chemical and Life Science Engineering Assistant Professor Leah Spangler, Ph.D., is an expert at instructing cells to make specific things. Her material science background employs proteins to build or manipulate products not found in nature, like purifying rare-earth elements for use in electronics. “My lab’s function is to make proteins every day,” says Spangler. “The kind of proteins we make depends entirely on the project they are for. More specifically I use proteins to make things that don’t occur in nature. The reason proteins don’t build things like solar cells or the quantum dots used in LCD TVs is because nature is not going to evolve a solar cell or a display surface. Nature doesn’t know what either of those things are. However, proteins can be instructed to build these items, if we code them to.” Spangler is collaborating with Peters in the development of his radial flow bioreactor, specifically to engineer a microorganismal bacteria cell capable of continuously producing biologic pharmaceuticals. “We build proteins by leveraging bacteria to make them for us,” says Spangler. “It’s a well known technology. For this project, we’re hypothesizing that Escherichia coli (E. coli) can be modified to make GLP-1. Personally, I like working with E. coli because it’s a simple bacteria that has been thoroughly studied, so there’s lots of tools available for working with it compared to other cell types.” Development of the process and technique to use E. coli with the radial flow bioreactor is ongoing. “Working with Dr. Spangler has been a game changer for me,” says Peters. “She came to the College of Engineering with a background in protein engineering and an expertise with bacteria. Most of my work was in mammalian cells, so it’s been a great collaboration. We’ve been able to work together and develop this bioreactor to produce GLP-1.” Other Radial Flow Bioreactor Applications Similar to how the GLP-1 peptide has found applications beyond diabetes treatment, the radial flow bioreactor can also be used in different roles. Peters is currently exploring the reactor’s viability for harnessing solar energy. “One of the things we’ve done with the internal disc is to use it as a solar panel,” says Peters. “The disk can be a black body that absorbs light and gets warm. If you run water through the system, water also absorbs the radiation’s energy. The radial flow pattern automatically optimizes energy driving forces with fluid residence time. That makes for a very effective solar heating system. This heating system is a simple proof of concept. Our next step is to determine a method that harnesses solar radiation to create electricity in a continuous manner.” The radial flow bioreactor can also be implemented for environmental cleanup. With a disk tailored for water filtration, desalination or bioremediation, untreated water can be pushed through the system until it reaches a satisfactory level of purification. “The continuous bioreactor design is based on first principles of engineering that our students are learning through their undergraduate education,” says Peters. “The nonlinear scaling laws and performance predictions are fundamentally based. In this day of continued emphasis on empirical AI algorithms, the diminishing understanding of fundamental physics, chemistry, biology and mathematics that underlie engineering principles is a challenge. It’s important we not let first-principles and fundamental understanding be degraded from our educational mission, and projects like the radial flow bioreactor help students see these important fundamentals in action.”
Protect yourself: Scammed by a QR Code? It didn’t have to happen
QR codes are used everywhere nowadays – to pay for metered parking, to read menus at restaurants, to win a free cup of coffee. Cybercriminals are using them, too – redirecting users to harmful websites that harvest their data. The practice is known as “quishing,” derived from QR code phishing, and it is a fast-growing cybercrime. But it doesn’t have to be. University of Rochester engineers Gaurav Sharma and Irving Barron have devised a new form of QR code – called a self-authenticating dual-modulated QR (SDMQR) – that protects smartphone users from quishing attacks by signaling when users are being directed to a safe link or a potential scam. Gaurav is a professor of electrical and computer engineering, computer science, and biostatistics and computational biology. Barron is an assistant professor of instruction in electrical computer engineering. Their creation involves allowing companies to register their websites and embed a cryptographic signature in a QR code. When the code is scanned, the user is notified that the code is from an official source and safe. Gaurav and Barron recently wrote about their technology in the journal IEEE Security and Privacy, and spoke about their work on the National Science Foundation's Discovery Files podcast. They can be reached by email at gaurav.sharma@rochester.edu and ibarron@ur.rochester.edu.
University of Delaware researchers have found that measuring brain stiffness is a reliable way to predict brain age. This information could be used to identify structural differences that indicate departure from the normal aging process, potentially identifying and addressing disorders such as Alzheimer’s disease and Parkinson’s disease. In recent findings, Curtis Johnson, associate professor of biomedical engineering, and Austin Brockmeier, assistant professor of electrical and computer engineering, show that measuring both brain stiffness and brain volume produces the most accurate predictions of chronological age. Their findings were published in a recent edition of the journal Biology Methods and Protocols. The pair worked with three current and former UD students to reach their conclusions. “Brain volume is a common measure that we use to study the brain,” Johnson said. “But something has to be happening to cause a brain to shrink. Something is happening at the microscale that causes it to shrink — changes in the tissue that also cause stiffness to change. And that precedes whatever happens when the volume changes.” “The stiffness maps all seem kind of random — until we see a large number of images and the randomness fades away and we start to see common patterns in stiffness,” Johnson said. “We sort of knew there was more [information] in there than what we were extracting." A cutting-edge magnetic resonance imaging (MRI) scanner at UD’s Center for Biomedical and Brain Imaging handled the brain scanning. On the artificial intelligence side, the brain maps were analyzed by three-dimensional “convolutional neural networks,” which — as the name suggests — are convoluted and complicated, incorporating many layers and dimensions. To arrange and interview with Johnson or Brockmeier, send an email to mediarelations@udel.edu
Expert Research: The Surprising Source of Next-Gen Antibiotics: Oyster Blood
Antimicrobial resistance (AMR) is a growing concern across the world and it has doctors worried and scientists working hard to find a solution Basically, AMR is when bacteria and viruses no longer respond to antimicrobial medicines. The result is making infections harder to treat and increases the risk of spreading disease. Recently, Texas Christian University researcher Shauna McGillivray commented on exciting new research in this area that was featured in the media: The search for a solution to antimicrobial resistance found something. And researchers found it in a true “it’s always the last place you look” location. Australian oysters. Or more specifically, Australian oyster blood. Antimicrobial proteins and peptides (AMPPs) “… are an exciting area with a lot of potential,” said Shauna McGillivray, professor of biology at TCU with an emphasis on host-pathogen interactions. “[They] are by themselves very potent but, as has been noted in multiple studies, they can also synergize with existing antibiotics, thereby improving efficacy of antibiotics, even in some cases to antibiotics to which there are high levels of resistance.” Feb. 22 -Phamed.com This is an amazing find and could be groundbreaking for the pharmaceutical industry and health care. And if you're looking to know more about this research and what it means for health care - then let us help. Shauna McGillivray, associate professor of biology is available to speak with media about her recent research - simply click on her icon now to arrange an interview today.
Lingam, Mirsayar, van Woesik Recognized as ‘Top Scholars’ by ScholarGPS
Florida Tech faculty members Manasvi Lingam, Mirmilad Mirsayar and Robert van Woesik were named “Top Scholars” by ScholarGPS for their contributions to academia over the last five years. Lingam, who studies astrobiology in the Department of Aerospace, Physics and Space Sciences, was ranked No. 9,562 in the world across all disciplines and nearly 15 million ranked scholars, placing him in the top 0.06% of the platform’s scholars globally. He faired strongly in other areas, including: No. 1,919 (0.1%) among 1.9 million scholars in physical sciences and mathematics No. 491 (0.09%) among 545,000 scholars in physics No. 42 (0.31%) among 13,590 scholars in the specialty area planets ScholarGPS cited Lingam’s strong publication record, the impact of his work and the notable quality of his scholarly contributions. He’s published 50 times since 2020, exploring the possible origins, evolution and future of life in the universe. Mirsayar, who studies aerospace engineering, was ranked No. 35,155 across all disciplines and nearly 15 million ranked scholars, placing him in the top 0.24% of scholars globally. He’s published 11 times between 2020-2023, covering topics such as fracture mechanics and solid mechanics. Other highlights include: No. 6 (0.06%) among 8,601 scholars in fracture mechanics No. 49 (1.7%) among 2,879 scholars in solid mechanics No. 315 (1.8%) among 16,847 scholars in reinforced concrete Van Woesik, who studies coral reef ecology, was ranked No. 58,081 across disciplines, putting him in the top 0.39% of nearly 15 million scholars globally. He’s had 22 publications since 2020, covering topics such as coral bleaching, thermal stress and climate change. Van Woesik, who studies coral reef ecology, was ranked No. 58,081 across disciplines, putting him in the top 0.39% of nearly 15 million scholars globally. He’s had 22 publications since 2020, covering topics such as coral bleaching, thermal stress and climate change. Other highlights include: No. 5,282 (0.32%) among 1.7 million scholars in life sciences No. 336 (0.38%) among 88,930 scholars of ecology and evolutionary biology No. 191 (0.95%) among 19,998 scholars of global change. ScholarGPS uses artificial intelligence and data mining technologies to rank individuals, academic institutions and programs. Scholars are ranked by their number of publications, their citations, their h-index and their ScholarGPS® Ranks, which includes all three metrics. If you're interested in connecting with Manasvi Lingam, Robert van Woesik and Mirmilad Mirsayar- simply contact Adam Lowenstein, Director of Media Communications at Florida Institute of Technology at adam@fit.edu to arrange an interview today.
Georgia Southern welcomes Georgia state leaders on Wexford Campus in Ireland
Georgia Southern University’s Wexford Campus in Ireland has been invigorating educational, civic, business and trade opportunities between Ireland’s southeast region and the state of Georgia since its establishment in 2022. The bicultural partnership has drawn the attention of state leaders in Georgia, prompting a recent visit to the international campus where Georgia Southern and its Irish partners welcomed the delegation. “We hosted legislators and leaders of industrial development and enterprise organizations,” said Howard Keeley, Ph.D., director of Georgia Southern’s Center for Irish Research and Teaching (CIRT). “These Georgia stakeholders believe that what Georgia Southern is doing in Ireland is important. One of the major concepts behind the Wexford Campus is that it’s a true campus, not just a study-abroad venue. So we’re pursuing several streams of activity. One is teaching and another is research. Another one is economic development, which includes internships and community engagement. We want to be in the community; therefore, to have leading constituents from a variety of industries in Georgia was very gratifying.” Among the attendees were U.S. Congressman Earl L. “Buddy” Carter; Georgia Department of Economic Development Commissioner Pat Wilson and five members of his senior staff, as well senior officials from electrical utilities, including Georgia Power; Trip Tollison, CEO of Savannah Economic Development Authority; Teresa MacCartney, chief operating officer for the University System of Georgia; and Georgia Rep. James Burchett (‘04), along with 10 additional members of the Georgia House of Representatives. “The main thing we wanted to do is show them what the student experience is like,” said Keeley. “We care about our students, and, using philanthropic funds, we’ve invested in a beautiful set of buildings, including one, built in 1886, that will house 50 students at a time. Each year, our goal is full capacity over six minimesters for a total of 300 Georgia Southern students. Historically a religious convent, that structure should open in spring 2026, after extensive remodeling. Many Georgia Southern students, including construction management and interior design majors, are gaining valuable professional skills by contributing to the endeavor.” The Wexford Campus already features the Learning Center, a historic administrative complex constructed in 1812 that has been transformed into a contemporary, high-tech educational space where students learn from local and international experts. They also present their research to peers and visiting Georgia Southern alumni while participating in high-impact experiential learning within the region. Visiting delegates were pleased to learn about the Honors College Global Scholars Program, which hosts 24 Honors College students who, taking an interdisciplinary approach, explore two themes for six weeks each spring in Ireland. This year, a prominent topic of study was sustainability in agriculture. One of Georgia Southern’s European research partners, South East Technological University Ireland, helped guide the students as they compared sustainability challenges along the coasts of Georgia and southeastern Ireland. The students drew on various research efforts, including important knowledge generated by Georgia Southern’s Institute for Water and Health. Similar integrated concepts also inform the summer and fall offerings. In 2024, they included two undergraduate global business courses, as well as the first Europe-based course from the MBA program at Georgia Southern’s Parker College of Business. One focus for the MBA students was Rosslare Europort, just south of Georgia Southern’s Wexford Campus, which has become Ireland’s fastest-growing port as multiple new direct routes to continental Europe have opened in response to Brexit. At a workshop facilitated by a top Rosslare Europort official, the MBA students explored international trade, logistics and supply chain management and the European regulatory environment. Spanning undergraduate, graduate and doctoral levels, the Wexford Campus has also provided courses in accounting, philosophy, sociology, geography, environmental biology, tourism and public health, among other disciplines. Shadowing Irish experts, population health science students from the Waters College of Health Professions focused on designing and delivering preventative-health programs, a critical matter in both Ireland and Georgia. “One of the metrics we use to measure success in Ireland is asking what makes it worthwhile for students to complete the course in Ireland as opposed to staying in the United States,” posed Keeley. “The bottom line is that we’re trying to provide a range of courses that look like Georgia Southern and that meet the degree needs, but also the employment needs in the state of Georgia. We’re always looking at how we can make our students more competitive, deepen their knowledge and give them as much hands-on experience as possible. This is really one of the things that we hope is a differentiator for us.” Notably, annual scholarships are available for the Honors College Global Scholars Program, Department of Political Science and International Studies students and Irish Studies students thanks to generous donations from alumni. In addition, philanthropic support has provided $1,000 to each participating student to offset the cost of transatlantic air travel. “The Wexford Campus’ directives exemplify Georgia Southern’s mission of providing holistic educational opportunities for our students to excel and grow,” said Annalee Ashley, Ed.D., Georgia Southern Vice President for External Affairs, Communications, and Strategic Initiatives, who participated in the trip. “Employers value global consciousness and intercultural skills when hiring, and our students who study abroad can enhance their skills, intellect and hireability in the marketplace. We are proud to serve Georgia and the entire southeastern region in this unique way, and to be supported by the state of Georgia as the University moves toward an R1 designation.” Beyond the campus, the group explored Johnstown Castle, an environmental and agricultural research center and heritage venue, as well as the Dunbrody Emigration Experience Center, whose newest permanent exhibition, Savannah Landing, is based on research by Georgia Southern students. The work highlights more than 170 years of historical ties that connect Savannah and Wexford, where hundreds boarded ships and crossed the Atlantic Ocean to arrive in Georgia’s coastal city in the mid-19th century. The centerpiece project, which was celebrated by the Irish prime minister at a ribbon-cutting in August, was made possible by $832,000 in research-grant funding, secured by the Dunbrody Center and Georgia Southern’s Center for Irish Research and Teaching. “Our guests got to experience history and understand the unique story that connects County Wexford to Savannah and, by extension, the state of Georgia,” noted Keeley. “Furthermore, they were able to see more than three-quarters of a million dollars of investment in Georgia Southern student work. That was super exciting.” The legislative group also met with Georgia Southern’s Irish partners, who shared what this relationship means to the people of Wexford and its hinterland, Southeast Ireland. “We invited all the players onto the field to strategically advance themes of education, economic development, and civic and cultural engagement,” said Keeley. “I believe they concluded that Ireland is a fit. It boasts a thriving economy that is modern, global and innovative. It’s the youngest economy in Europe in terms of workforce, and Ireland is one of the biggest investors in the U.S. economy.” Georgia Southern leadership and local Irish legislators, including four members of the Irish House of Representatives, Senator Malcolm Byrne and members of Wexford County Council, hosted Georgia’s VIPs with open arms. “They wanted to rally around us in the way that a family will rally around you,” said Keeley. “They couldn’t have done more. They totally rolled up their sleeves. It was a complete partnership hosting, and we were able to demonstrate that our network is so solid.” Wexford County Council leader Pip Breen shared opportunities for deeper connections with the Georgia delegation through the Irish nonprofit TradeBridge. Established in 2018, the entity facilitates trade and investment between the southeastern regions of Ireland and Georgia by developing new export markets and job creation opportunities. The trade corridor opens doors for southeastern Irish companies to establish a supportive base in southeastern Georgia, while also creating similar coordinates for companies based in southeastern Georgia to enter the European Union marketplace. Keeley, who was awarded the Presidential Distinguished Service Award for the Irish Abroad from the Government of Ireland in 2023, is a board member. “Georgia Southern’s footprint in southeastern Ireland is an important one for students and for the state of Georgia,” said Ga. Rep. Burchett. “The strides they are making not only allow students to participate in research in engineering, coastal sustainability, history and other important areas of study, but they also directly drive trade and investment opportunities between the southeastern regions of Georgia and Ireland. This was an amazing visit and we value our friendships within the Irish community.” Following the event, Burchett returned the hospitality with an invitation for Wexford County Council members to be recognized in person on the floor of the Georgia General Assembly in March 2025. “They very enthusiastically accepted the invitation,” Keeley shared. “I think when you’re involved in education, when you’re doing business and when you’re building out opportunities, the most important single thing is friendship and like-mindedness. You cannot achieve anything otherwise. There has to be this human-to-human connection. There has to be genuine mutual respect and mutual affection, and that was just in spades.” Georgia Southern’s Wexford Campus was featured on the national Irish TV program, “Nationwide.” You can see it here: Looking to know more, then let us help. Howard Keeley, director of Georgia Southern’s Center for Irish Research and Teaching, is available to speak with media. Simply click on his icon now to arrange an interview today.
New study shows alarming rate of potential species extinction due to climate change
A recent study authored by the University of Connecticut's Mark Urban found that close to one third of species across the globe would be at risk of extinction by the end of the century if greenhouse gases continue to increase at current levels. His study, published in the journal Science, looked at more than three decades of biodiversity and climate change research. The findings are alarming. The study found that if global temperatures rise to 2.7 degrees Fahrenheit (1.5 degrees Celsius) above the pre-industrial average temperature, exceeding the target of the Paris Agreement, extinctions would rapidly accelerate — especially for amphibians; species in mountain, island and freshwater ecosystems; and species in South America, Australia and New Zealand. Earth has already warmed about 1.8 F (1 C) since the Industrial Revolution. Climate change causes shifts in temperatures and precipitation patterns, altering habitats and species interactions. For instance, warmer temperatures have caused monarch butterfly migration to mismatch with the blooming of plants they pollinate. Many animal and plant species are shifting their ranges to higher latitudes or elevations to follow more favorable temperatures. While some species might adapt or migrate in response to changing environmental conditions, some can't survive the drastic environmental changes, resulting in population declines and sometimes extinction. Global assessments have predicted rising extinction risks for over a million species, but scientists have not clearly understood how exactly this growing risk is linked to climate change. The new study, published Thursday (Dec. 5) in the journal Science, analyzed over 30 years of biodiversity and climate change research, encompassing over 450 studies of most known species. If greenhouse gas emissions are managed in accordance with the Paris Agreement, nearly 1 in 50 species worldwide — an estimated 180,000 species — will be at risk of extinction by 2100. When the climate model's temperature is increased to a 4.9 F (2.7 C) rise, which is predicted under current international emissions commitments, 1 in 20 species around the world would be at risk of extinction. Hypothetical warming beyond this point makes the number of species at risk rise sharply: 14.9% of species were at risk of extinction under a 7.7 F (4.3 C) warming scenario, which assumes high greenhouse gas emissions. And 29.7% of all species would be at risk of extinction under a 9.7 F (5.4 C) warming scenario, a high estimate, but one that is possible given current emissions trends. The increase in the number of species at risk increases steeply beyond the 1.5 C warming target, study author Mark Urban, a biologist at the University of Connecticut told Live Science. "If we keep global warming to below 1.5 C, in accordance with the Paris Agreement, then the [extinction] risk from today to 1.5 C is not a large increase," Urban said. But at a 2.7 C rise, the trajectory accelerates. Species in South America, Australia and New Zealand face the greatest threats. Amphibians are the most threatened because amphibians' life cycles depend heavily on weather, and are highly sensitive to shifting rainfall patterns and drought, Urban said. Mountain, island and freshwater ecosystems have the most at-risk species, likely because these isolated environments are surrounded by inhospitable habitats for their species, making it difficult or impossible for them to migrate and seek more favorable climates, he added. Limiting greenhouse gas emissions can slow warming and halt these growing extinction risks, but understanding which species and ecosystems are most affected by climate change can also help target conservation efforts where they're needed most. Urban hopes the results have an impact on policymakers. "The main message for policymakers is that this relationship is much more certain," Urban said. "There's no longer the excuse to do nothing because these impacts are uncertain." December 5, 2024 - Live Science This is an important topic, and if you're a journalist looking to learn more, we can help. Mark Urban is an international award-winning scientist; a professor of ecology and evolutionary biology and the Arden Chair Ecology & Evolutionary Biology at UConn; and a global expert on climate change impacts on nature. He is available to speak with media - simply click on his icon now to arrange an interview today.
Humans have long taken inspiration from the natural world. From the indigenous cultures of the world who understand and utilize the properties of plant and animal products, to Leonardo da Vinci’s “flying machine” sketches inspired by his observations of flying birds, humankind has often looked to nature to help solve its problems and drive innovation. With rapid scientific advancements of the 19th and 20th centuries, and the exponential growth of sustainability practices over the last quarter century, the concepts of bio-inspired design and biomimicry have been increasingly pursued across myriad disciplines of study and implementation. Alyssa Stark, PhD, associate professor of biology at Villanova University, is one of the “boots-on-the-ground” researchers in pursuit of nature’s solutions to human problems. She recently took the time to chat with us about these fields, her research interests and the future of biomimicry. Villanova PR: We sometimes hear the terms “bio-inspired design” and “biomimicry” used interchangeably. Are they the same concept? Alyssa Stark: I see those as two different things. Bio-inspired design is when we are looking at an organism and see that it’s doing something that we want to emulate as humans. I work with animals that have unique adhesive properties. I ask questions like: Can we see that? Can we build it? Can we transfer that information, those ideas, those principles – it could be chemistry, physics, biological structure – and make something useful for us? That is also true with biomimicry, but the big difference for me is that we're keeping in mind the sustainability components. The natural world is not polluting. If we're using this biomimicry lens, how do we learn from nature to make products or solve problems in a sustainable way, keeping in mind the specific environment in which we are located? As an example, we wouldn't use a heavy water process if we were in the Arizona desert, instead we should look to our immediate surroundings to solve problems. PR: It seems the work going on in this field really takes a unique level of interdisciplinary collaboration. What types of different professionals are working in biomimicry? AS: It really pulls together biologists, engineers, physicists, chemists, even design artists and businesspeople. I've worked with a lot of different businesses that want to have sustainability in their company at broad levels by using biomimicry. They are not motivated by making a cool product, but realizing it actually saves them money if they think about their whole company in a biomimetic perspective. There are people who work on the social side of biomimicry, helping these companies completely restructure themselves to be more efficient and more time and money sensitive, without ever making a product. But of course, products are a huge part of it, too. And to make that happen, all of those professions, and more, are vital and active in this space. PR: In terms of products, what are some of the most successful examples of biomimetic designs being implemented? AS: A classic one is a building in Africa that doesn't have any air conditioning units because it has a series of vents like a termite mound. Or the bullet train being shaped like a kingfisher’s beak. One scientist found that whales have bumps on their fins, which you might think is not hydrodynamic. But as it turns out, it actually cuts through water more efficiently by creating little vortices. This concept was then applied to wind turbines. There are many examples of biomimicry actually working and being used. My mind is blown when I talk to an artist or designer about biomimicry because it's just wild the way they think. PR: Where does your overall work as a biologist fit into the world of biomimicry? AS: My hard science work is very much functional morphology – shape and structure of things and how they function. That includes behavior and their organismal interaction with the environment. I ask questions like: How do their structures function and perform? How sticky are they? How fast are they? How do they behave in their environment? What happens if they hit different challenges in their environment? My work kind of naturally fits well with biomimicry, especially for product development. I observe the natural world and then I start testing questions and predictions that I have about it, like figuring out how the heck this ant is sticking to this wet leaf. My results can then be applied directly. We have to first understand how these organisms work, and then others can run with it to try to put it to use. PR: What organisms do you work with and what about them are you studying? AS: I mostly study geckos, ants, and sea urchins and I just started working with some coral, looking at why some coral undergo bleaching, and some don’t. With sea urchins, we're also figuring out where their incredibly hard teeth are mineralized so we can understand it enough to try to mimic it. I like playing in that zone, because it still provides me a chance to do the hard science, but also talk to engineers and others and provide them information. With geckos, what I kind of broke open with my PhD thesis was that they have an adhesive that works in wet environments. Having a reusable adhesive that can work on skin, especially in the medical world, is a big problem and where most of my research lies. Think of a bug that you can’t pry off, but then it suddenly runs. How do these organisms move with such sticky feet? Figuring out how to make a reusable adhesive that doesn’t get dirty and can handle all these different environments is a difficult problem to solve. PR: How do you see this field evolving, especially as we strive for a greener, more sustainable future? AS: I would say the next step is the social levels of these big ecosystems. How do we build a city that functions like a rainforest or like a coral reef? Not just a product, but how do we actually shape our world by taking behaviors, processes, or systems that we see in the natural world to help us? Look at a pride of lions and their hierarchy, or what kind of feedback loops are there in an ant colony that allow them to give information back to their colony members quickly and share resources. I think that is the future of this field, and it’s an exciting future. *To learn more about Dr. Stark’s research and the field of biomimicry, click here to listen to a recent episode of NPR’s science show, “The Pulse.”
