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New light technique could revolutionise non-invasive medical diagnostics Orbital Angular Momentum could be harnessed to improve imaging and data transmission through biological tissues Could eventually have potential to make procedures such as surgery or biopsies unnecessary. An Aston University researcher has developed a new technique using light which could revolutionise non-invasive medical diagnostics and optical communication. The research showcases how a type of light called the Orbital Angular Momentum (OAM) can be harnessed to improve imaging and data transmission through skin and other biological tissues. A team led by Professor Igor Meglinski found that OAM light has unmatched sensitivity and accuracy that could result in making procedures such as surgery or biopsies unnecessary. In addition it could enable doctors to track the progression of diseases and plan appropriate treatment options. OAM is defined as a type of structured light beams, which are light fields which have a tailored spatial structure. Often referred to as vortex beams, they have previously been applied to a number of developments in different applications including astronomy, microscopy, imaging, metrology, sensing, and optical communications. Professor Meglinski in collaboration with researchers from the University of Oulu, Finland conducted the research which is detailed in the paper “Phase preservation of orbital angular momentum of light in multiple scattering environment” which is published in the Nature journal Light Science & Application. The paper has since been named as one of the year’s most exciting pieces of research by international optics and photonics membership organisation, Optica. The study reveals that OAM retains its phase characteristics even when passing through highly scattering media, unlike regular light signals. This means it can detect extremely small changes with an accuracy of up to 0.000001 on the refractive index, far surpassing the capabilities of many current diagnostic technologies. Professor Meglinski who is based at Aston Institute of Photonic Technologies said: “By showing that OAM light can travel through turbid or cloudy and scattering media, the study opens up new possibilities for advanced biomedical applications. “For example, this technology could lead to more accurate and non-invasive ways to monitor blood glucose levels, providing an easier and less painful method for people with diabetes.” The research team conducted a series of controlled experiments, transmitting OAM beams through media with varying levels of turbidity and refractive indices. They used advanced detection techniques, including interferometry and digital holography, to capture and analyse the light's behaviour. They found that the consistency between experimental results and theoretical models highlighted the ability of the OAM-based approach. The researchers believe that their study’s findings pave the way for a range of transformative applications. By adjusting the initial phase of OAM light, they believe that revolutionary advancements in fields such as secure optical communication systems and advanced biomedical imaging will be possible in the future. Professor Meglinski added: "The potential for precise, non-invasive transcutaneous glucose monitoring represents a significant leap forward in medical diagnostics. “My team’s methodological framework and experimental validations provide a comprehensive understanding of how OAM light interacts with complex scattering environments, reinforcing its potential as a versatile technology for future optical sensing and imaging challenges.” ENDS https://www.nature.com/articles/s41377-024-01562-7 Light: Science & Applications volume 13, Article number: 214 (2024) August 2024 https://doi.org/10.1038/s41377-024-01562-7 Authors: Igor Meglinski, Ivan Lopushenko, Anton Sdobnov & Alexander Bykov About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
ChristianaCare and Partners Launch Delaware’s First Nurse Anesthesiology Program
Wilmington University, in collaboration with ChristianaCare and the support of Anesthesia Services, P.A. (ASPA), announces the Delaware Nurse Anesthesiology Program at ChristianaCare and Wilmington University, Delaware’s first nurse anesthesiology program. This innovative, full-time, 36-month offering leads to a Doctor of Nursing Practice (DNP) degree, preparing graduates to sit for the National Certification Exam and become certified registered nurse anesthetists (CRNAs). A CRNA (or nurse anesthetist) is an advanced practice registered nurse who administers anesthesia and provides related care before, during, and after surgical, therapeutic, diagnostic, and obstetrical procedures. The program will offer students over 2,000 hours of hands-on clinical experience in high-acuity environments across various surgical specialties, supported by partnerships with ChristianaCare, ASPA—the largest anesthesia group in Delaware—as well as other health care organizations. Students will refine their clinical skills and decision-making in state-of-the-art simulation labs while engaging in diverse clinical settings. Led by experienced practitioners and educators, the curriculum integrates anesthesiology-specific coursework with advanced nursing practice, ensuring graduates are well-prepared to meet the evolving demands of clinical practice and systemic health care challenges. “We are proud to partner with ChristianaCare and ASPA to launch this transformative program,” says Wilmington University President Dr. LaVerne Harmon. “At Wilmington University, our caring, student-centered approach prioritizes academic excellence and personal well-being. While this initiative addresses Delaware’s critical need for anesthesiology professionals, we will focus equally on fostering an environment where students can excel and grow into compassionate, skilled leaders in the evolving health care field.” “ChristianaCare is excited to partner with Wilmington University and our colleagues at ASPA in this much needed program to help address Delaware’s growing need for highly qualified CRNAs,” says Janice E. Nevin, M.D., MPH, president and CEO of ChristianaCare. “By providing advanced training and education in anesthesiology services, we are helping to develop the next generation of health care experts who will serve our community with high-quality, safe care.” The U.S. Bureau of Labor Statistics projects a 38% growth in nurse anesthetist employment from 2022 to 2032, driven by increased demand for health care services like elective surgeries. Delaware’s health care system faces similar challenges due to a shortage of anesthesiologists and CRNAs, with many nearing retirements. With 15 programs in neighboring Pennsylvania unable to accommodate all qualified applicants, the Delaware Nurse Anesthesiology Program at ChristianaCare and Wilmington University aims to bridge this gap, providing essential local training to meet the growing demand in the workforce. “With an emphasis on evidence-based practice and patient-centered care, our graduates will be exceptionally equipped to provide high-quality anesthesiology services in diverse health care environments,” says Wilmington University Vice President of Academic Affairs Dr. Denise Wells. “This collaboration aims to cultivate a local pipeline of skilled registered nurses who will advance their careers as CRNAs, contributing to Delaware’s workforce and the surrounding region.” “Anesthesia Services, P.A. has been leading and innovating anesthesia care delivery in Delaware for the past 37 years,” says ASPA Board Chair Li Maceda, M.D., MBA. “This joint partnership with ChristianaCare and Wilmington University allows us to combine our expertise and resources to train the next generation of anesthesia providers for the communities that we serve and exemplifies our commitment to invest in the future advancement of perioperative care.” Dr. Jacqueline Mainwaring was recently named inaugural director of the Delaware Nurse Anesthesiology Program at ChristianaCare and Wilmington University. “I am excited to be part of this groundbreaking initiative that will provide critical care nurses in our state with the opportunity to advance their careers and become leaders in anesthesiology care,” says Dr. Mainwaring, also an associate professor. “We are committed to creating a high-quality program that prepares our graduates to excel in today’s complex health care landscape. This program will not only address the shortage of anesthesiology professionals in Delaware and the region but will foster a learning environment that emphasizes student well-being, clinical excellence, and interprofessional collaboration.” Leaders of the Delaware Nurse Anesthesiology Program at ChristianaCare and Wilmington University, currently in Capability Review, are pursuing initial accreditation from the Council on Accreditation of Nurse Anesthesia Educational Programs (COA). Please note, no students can be enrolled until initial accreditation has been awarded. Below is contact information for the COA: Council on Accreditation of Nurse Anesthesia Educational Programs (COA) 10275 W. Higgins, Suite 906 Rosemont, IL 60018 Phone: 224-275-9130 Email: accreditation@coacrna.org www.coacrna.org
It's the right of every citizen - and with a presidential election less than two weeks away, a team of social workers from UConn are working to make sure every voice is heard as the U.S. choses a new leader on Nov. 5. Voting Is Social Work - a campaign led by Tanya Rhodes Smith, director of the Nancy A. Humphreys Institute for Political Social Work at the UConn School of Social Work - is getting a lot of attention for its work engaging social workers to help empower some of the most vulnerable and disenfranchised groups to get registered and cast their ballots in local elections. “Voting is complicated, and it’s intimidating, especially for vulnerable populations, like the unhoused, the formerly incarcerated, or those living in congregate care,” says Rhodes Smith. “We know that being a non-voter is a very isolating space, because voting is highly relational. Campaigns generally ignore non-voters— you don’t get campaign materials, or someone knocking on your door. Information on candidates in state and local elections in communities with low turnout can be very hard to find or even nonexistent.” That’s where social workers, explains Rhodes Smith, can play an important role in helping disenfranchised voters understand their rights – and register to vote. Money, Power, and Resources As co-founders since 2015, UConn’s Humphreys Institute has been the institutional home for Voting Is Social Work. Also known as the National Social Work Voter Mobilization Campaign, Voting Is Social Work supports nonpartisan voter engagement as central to social work’s mission, ethical mandate, and impact. “We’ve always believed that social work has the power to transform democracy,” says Rhodes Smith, “and we believe every social worker – and social service agency – should include nonpartisan voter engagement into their practice and work. Because we reach non-voters – those who are least likely to vote.” October 16 - UConn Today It's an initiative catching attention across the country. Research has linked voting to higher earning and education, better health outcomes, and lower rates of recidivism. But education is key, particularly for individuals with special circumstances, like the formerly incarcerated, people living in congregate care, and the unhoused. Homelessness comes with a new, unique set of challenges during an election cycle. However, homeless residents have protections, including voting rights. Nationwide, only 10% of unhoused people vote each year, according to the Institute of Political Social Work at the University of Connecticut. Many social workers in Connecticut are working to educate unhoused residents about their voting rights, according to UConn Social Work professor Tanya Rhodes Smith, director of the Nancy A. Humphreys Institute for Political Social Work. “When you ask somebody if they would like to check their voter registration, they may say, ‘I'm not eligible,’ or ‘I've never voted,’ and that's really important information for you to know,” Rhodes Smith said. “It really tells a story about them.” About 60% of eligible voters turnout in presidential election years, but increasing voting rates is important for local elections as well, Rhodes Smith said. “When you have 10% to 15% [voter turnout], that's not an accountable government, that's a government that's accountable to the 10% to 15%,” Rhodes Smith said. “We've seen it over and over in Bridgeport, that nothing changes because that turnout rate doesn't go up, and so there is no accountability when you have an unhealthy democracy.” October 10 - WNPR Looking to know more about this important work? If so, let us help. Tanya Rhodes Smith specializes in policy development, nonprofit administration, voter engagement and legislative advocacy. She's available to speak with media about this important topic - simply click on her icon now to arrange an interview.
Welcome to Retire with Equity: Where a New Retirement Journey Begins
Summary: A recent study reveals that 40% of Canadians over 50 feel financially unprepared for retirement. Retire with Equity aims to address this issue by educating retirees on the importance of leveraging home equity. The initiative emphasizes transparency, financial literacy, and personalized guidance to help seniors make informed decisions and achieve financial security in retirement. According to a recent National Institute of Aging study, almost 40% of Canadians over 50 feel they are not financially prepared for retirement. As a seasoned citizen myself, I know we can do better. That's why we've created Retire with Equity. It's time to help Canadians get the knowledge they need to make more informed financial decisions. My observations from my time in the industry, enriched by the research I've done over the past few years, clearly reveal a growing retirement crisis in Canada. I've worked in the banking and mortgage industry for over 25 years, specializing in equity lending, and spent the last 6 years as an executive at Canada’s largest Reverse Mortgage bank. Many people are struggling with mounting debt and no company pension. And they are living longer. Additionally, the long-term care situation in Canada has many seniors looking to age in place in their homes. Strategies like downsizing and moving in with family are often too simplistic and have little appeal to today's seniors. Some eventually, often begrudgingly, turn to home equity options such as reverse mortgages as a solution. However, Canadians are conservative by nature, and many think it is taboo to touch their equity (nest egg). Consequently, a reverse mortgage is a last resort. 76% of people over 65 are homeowners, many of which have built up a substantial amount of equity yet cannot afford to retire. (Source: Statistics Canada) Income is the only way to solve the retirement crisis. Many are choosing to work longer to delay spending savings. Some need to pay off debt to eliminate payments that will free up cash flow. Others do not have enough savings to retire. I saw the stress this caused watching my Mother “do without” in her retirement. With the benefit of experience, I now know there was a better way for her to finance her golden years. The Retirement Problem in Canada is Dire Many 55+ Seniors Don’t Have the Funds They Need: Many need an adequate budget and financial plan. And many don’t fully realize that employer and government pensions will fall short of their cashflow needs. Home Equity Unlocks Opportunities, But It's Misunderstood: Many retirees don’t fully understand the short—and long-term impacts of their home equity financing decisions. They rely on biased, incomplete, anecdotal information from friends and family. Seniors Need to Be Cautious: Homeowners are especially vulnerable targets for misinformation and fraud. However, this demographic does not have time to recover from a financial mistake. Making the wrong choices that affect how they finance retirement and protect themselves could leave seniors without enough money later when they need cash for costly expenses like health care. The Financial Industry Needs to Do More: There is a need for unbiased, transparent, and trusted sources of information on home equity options that are aligned with consumer interests. Gone are the days of cookie-cutter retirement plans and guaranteed pensions. Every Canadian needs to proactively craft their unique vision and path for retirement. Banking on My Experience The Retire With Equity mission is dedicated to helping retirees find the right combination of financial strategies to achieve their goals. The Equity Advantage One of the standout features of Retire with Equity's approach is our focus on home equity as a key component of retirement planning. For many Canadians, their home is their most significant asset, and unlocking its potential can be a game-changer. Whether through downsizing, refinancing, or reverse mortgages, Retire with Equity will offer guidance on integrating this valuable resource into a retirement strategy. The Human Touch At Retire with Equity, we promise to offer straightforward advice with a personal touch. It's not just about the numbers – it’s also about the dreams you have for retirement. We will bring patience, empathy, and respect to every conversation. And we won't forget our sense of humour, as retirement is supposed to be fun. We're committed to making things easy to access and understand, no matter where you are in life. Education is Everything Two of our core values are empowering education and epic transparency. Our online resources, webinars, and workshops will be tailored to demystify the world of finance for retirees and soon-to-be retirees, increasing their financial literacy. We will bring transparency to the vital information reserved for the small print, answering the questions retirees don't even know to ask. Whether you're a financial guru or just starting to think about your nest egg, we'll have something for you. A Senior-Friendly Approach Our approach will integrate technology with a user-friendly interface so that retirees can access their services without hassle. Gone are the worries of getting stuck in the weeds of complex interfaces or endless financial jargon. We bring "kitchen table" logic when explaining all financial details, no matter how complex the concept is. Stories that Inspire From coast to coast, Retire with Equity will share personal stories that help educate and motivate Canadians. We want to show you visible proof that it's always possible to rethink and revitalize retirement plans. Hearing from fellow Canadians who have successfully navigated the retirement waters offers hope for those still planning their way. Feelings of guilt and shame are common among retirees searching for retirement options. Learning about countless other retirees in similar situations often alleviates this guilt and shame. Join the Revolution Retire with Equity is more than just a company—it’s a movement. Canadians across the country will join in and transform their retirement years into the best chapter of their lives. Empowered by new tools and expertise at their fingertips, they will not just survive but truly thrive in retirement. As an "Equity Advocate," I pledge to help Canadians navigate the complexities of retirement in ways that educate, inspire, and entertain. I look forward to the conversation. Please subscribe to our regular updates and follow us on social media. Here's to the best years ahead! Don't Retire---Re-Wire! Sue
The Must-Watch Scary Movies for Every Fear Factor
Spooky season has arrived, and there's no better way to get into the spirit than by enjoying some classic horror films. Whether you thrive on the thrill of a good scare or you’re more of a “hide your eyes” type, James Kendrick, Ph.D., a film historian and professor of film and digital media at Baylor University, has got you covered. From spine-tingling classics to not-so-scary flicks, Kendrick is here to help you navigate the perfect lineup of Halloween movies – no matter your fear tolerance. What makes horror movies scary? According to Kendrick, great horror films resonate with audiences by reflecting societal fears. "We are the monster," Kendrick said. Whether it's current social anxieties, cultural challenges or deep psychological fears, horror films have evolved to capture the essence of what we fear most, he said. The genre's core remains rooted in three essential elements: character and story, atmosphere and the monster. Without these, Kendrick said, the fear factor simply doesn’t work. Top 10 Horror Films Everyone Should See For those seeking true horror classics, Kendrick has developed a list of 10 must-watch films that exemplify the genre at its best. From early black-and-white masterpieces to modern independent hits, here are his recommendations: 1. Nosferatu (1922) 2. The Bride of Frankenstein (1935) 3. Cat People (1942) 4. Psycho (1960) 5. Night of the Living Dead (1968) 6. The Exorcist (1973) 7. Suspiria (1977) 8. Halloween (1978) 9. The Shining (1980) 10. The Babadook (2014) These films not only shaped the horror genre but also continue to be influential today, delving into psychological terror, societal anxieties and primal fears, Kendrick said. For the Faint of Heart: Scary Movies Without the Gore For those who want to enjoy the Halloween season without being overwhelmed by gore and violence, Kendrick offers his top 10 list of "terror" films that rely more on atmosphere and suspense than graphic horror. According to Kendrick, these terror films engage the audience emotionally and psychologically, drawing them into the fear without overwhelming them. The Innocents (1961) and A Quiet Place (2018) create tension and fear through the effective use of atmosphere, silence and emotional depth, he said. Kendrick’s top picks for lighter horror films include: 1. Vampyr (1932) 2. The Innocents (1961) 3. Kwaidan (1964) 4. Invasion of the Body Snatchers (1978) 5. The Vanishing (1988) 6. The Blair Witch Project (1999) 7. The Others (2001) 8. Take Shelter (2011) 9. Warm Bodies (2013) 10. A Quiet Place (2018) So, whether you’re a horror aficionado looking for spine-chilling classics, or just want to dip your toes into something a little spooky without the nightmares, Kendrick’s expert recommendations offer a Halloween movie night that’s perfect for everyone, thrill-seekers or scaredy-cats alike. Get your popcorn ready, turn off the lights (if you dare) and settle in for a frightfully good time this spooky season! ABOUT BAYLOR UNIVERSITY Baylor University is a private Christian University and a nationally ranked Research 1 institution. The University provides a vibrant campus community for more than 20,000 students by blending interdisciplinary research with an international reputation for educational excellence and a faculty commitment to teaching and scholarship. Chartered in 1845 by the Republic of Texas through the efforts of Baptist pioneers, Baylor is the oldest continually operating University in Texas. Located in Waco, Baylor welcomes students from all 50 states and more than 100 countries to study a broad range of degrees among its 12 nationally recognized academic divisions. Learn more about Baylor University at www.baylor.edu. ABOUT THE COLLEGE OF ARTS & SCIENCES AT BAYLOR UNIVERSITY The College of Arts & Sciences is Baylor University’s largest academic division, consisting of 25 academic departments in the sciences, humanities, fine arts and social sciences, as well as 11 academic centers and institutes. The more than 5,000 courses taught in the College span topics from art and theatre to religion, philosophy, sociology and the natural sciences. The College’s undergraduate Unified Core Curriculum, which routinely receives top grades in national assessments, emphasizes a liberal education characterized by critical thinking, communication, civic engagement and Christian commitment. Arts & Sciences faculty conduct research around the world, and research on the undergraduate and graduate level is prevalent throughout all disciplines. Visit the College of Arts & Sciences website.
At a gala event for Harmony Healthcare Long Island (HHLI), Martine Hackett, chair and associate professor of the Department of Population Health, School of Health Sciences (SHS), received the Mission Driven Award for her long-standing dedication to improving public health and advocating for underserved communities. The event honored community leaders who have made significant contributions to advancing healthcare access and equity. Hackett has been a tireless advocate for maternal and child health and health equity. Over the years, she has spearheaded numerous initiatives aimed at addressing racial disparities in healthcare, particularly in minority and low-income communities. Hackett’s leadership and passion for public health have left a lasting impact on the communities she serves. Corinne Kyriacou, vice dean for administration, SHS, associate professor of population health, a longtime colleague and member of the HHLI Gala Planning Committee, praised Hackett’s contributions. “Martine has always been driven by a genuine commitment to improving the lives of others. Her work goes beyond the classroom and touches the hearts of the communities she works with. She truly embodies the spirit of service and dedication,” Kyriacou said. Reginald Alston, dean of SHS, echoed these sentiments. “Martine’s impact on the field of public health and the students she mentors is immeasurable. She is a model of what it means to use education and research for the betterment of society. We are incredibly proud to have her as part of our Hofstra family,” Alston said. The gala, which celebrated HHLI’s growth and accomplishments over the past 15 years, highlighted Hackett’s numerous community partnerships and her ongoing work to promote health equity.
AU study shows participation in civil society groups lowers suicide rates
A new study by Lance Hunter, PhD, professor of social science in Augusta University’s Pamplin College of Arts, Humanities, and Social Sciences, reveals a direct link between voluntary involvement in civil social groups and a lower risk of suicide. In the study, published in Cross-Cultural Research, Hunter looked at data gathered from 2000 to 2019 from 156 countries with varying levels of development from Africa, Asia, Australia, Europe, North America and South America and found that participation in civil society groups, both political and non-political, may produce positive social and psychological benefits that are associated with lower suicide rates. September is National Suicide Prevention Month, during which mental health advocates, prevention organizations and other community groups promote suicide prevention awareness. “The greater the voluntary participation in civil society groups within the country, the lower the suicide rates are for that country,” said Hunter. “Voluntary civil society participation is a great way for people to connect with other individuals with similar interests and possibly find meaning and purpose to some degree. That in turn decreases feelings of social isolation, which can decrease the likelihood of suicidality or suicide.” Based on the research, he noted that social isolation is a major factor in suicide ideation and attempted suicide but it’s not the only factor. “It is important to note there are many psychological, biological, social and mental health factors that can contribute to suicide risk. Civil society participation and social isolation are just two factors among many that can affect suicidality,” said Hunter. Meredith Rausch, PhD, associate professor in the College of Education and Human Development’s Department of Research, Counseling and Curriculum, said research shows ideation and deaths by suicide in the United States tend to rise between February and April and again in August and September. “I have found the change in seasons often leads to people feeling overwhelmed when it comes to thinking about enduring another season,” said Rausch. “While the advent of spring or autumn may seem enjoyable or hopeful to some people, others find it to represent an entirely new season and the idea of experiencing that is exhausting.” Rausch also notes it’s important to note how these times of the year also coincide with the academic year, causing an increase in bullying, frustration with academics or other negative experiences for school-aged children. According to a 2023 study by the World Health Organization, more than 700,000 people worldwide die each year by suicide, and suicide is the fourth-leading cause of death among people 15 to 29 years old. Interested in learning more - let us help. Lance Hunter, PhD, is available to speak with media about this important topic - simply click on his icon to arrange an interview today.
The role of digital media in children's literacy
From tablets and smartphones to computers and smart TVs, kids have more access to digital content than ever before. But what does this mean for their literacy skills? One University of Delaware professor is embracing the use of digital media to improve children's literacy. Roberta Michnick Golinkoff, chair and professor in the School of Education UD, created Stories with Clever Hedgehog last year to offer books to children, specifically those who have been displaced or impacted by the Russo-Ukrainian War. This website allows families all over the world to engage in shared reading with their children, facilitate early literacy development and promote children’s well-being. Much research in early childhood education has underscored the importance of reading early and often with children, beginning during a child’s infancy and continuing throughout the elementary years. Reading during this critical point in children’s development fosters language acquisition, early literacy skills, socioemotional growth and comprehension of the world around them. Golinkoff's research partners and many others have demonstrated that shared book reading — when a child reads with a caregiver — encourages children to ask questions and draw connections to their own experiences, promotes story comprehension, increases children’s vocabulary and provides opportunities for emotional bonding. She is available to discuss even more benefits of reading, especially in this digital format. To connect, click her profile. She has been featured
Post-Pandemic: How Alcohol Is Harming the Health of More Women
The prevalence of alcohol-related complications has been steadily increasing over the years, but a significant surge occurred during the pandemic, particularly among women aged 40 to 64. According to a JAMA Health Forum report titled High-Acuity Alcohol-Related Complications During the COVID-19 Epidemic, there was a significant increase in severe alcohol-related complications in women and alcoholism. The majority of these, 54% to 66%, were alcohol-related liver disease; smaller numbers, 3% to 5% and 1% to 3% were attributed to alcohol-related cardiomyopathy and alcohol-related gastritis with bleeding, respectively. What the trends mean If these trends persist, the increases in alcohol-related complications will continue to harm women. There are several reasons explaining this increase. In addition to the overall increase in alcohol consumption, the pandemic exacerbated feelings of loneliness and uncertainty about the future. Additionally, lockdowns led to more time spent at home – an environment where alcohol is readily available. How alcohol affects women Women are particularly vulnerable to the adverse effects of alcohol due to differences in body structure and chemistry. They absorb more alcohol and take longer to metabolize it. This means smaller amounts of alcohol can cause more serious health issues. Also, the shift towards drinking at home, which was further made easier by convenient online shopping and home delivery during the pandemic, led to increased consumption without judgment. Addressing any substance misuse needs a multimodal approach. There are treatment options and medications that can help. It is important to wean yourself off alcohol with a doctor’s supervision, as withdrawal can be severe and dangerous. Getting help Health care providers, patients and their loved ones can all partner in enhancing education and awareness about alcohol use risks and reducing stigma in seeking treatment when needed. It’s important for women to recognize that they are not alone and that help is available. It is a difficult addiction for anyone to go through, but education and support can significantly improve outcomes.
Aston University develops novel bone cancer therapy which has 99% success rate
Bioactive glasses, doped with gallium developed to create a potential treatment for bone cancer Lab tests have a 99 percent success rate of killing cancerous cells Method could also regenerate diseased bones. Bioactive glasses, a filling material which can bond to tissue and improve the strength of bones and teeth, has been combined with gallium to create a potential treatment for bone cancer. Tests in labs have found that bioactive glasses doped with the metal have a 99 percent success rate of eliminating cancerous cells and can even regenerate diseased bones. The research was conducted by a team of Aston University scientists led by Professor Richard Martin who is based in its College of Engineering and Physical Sciences. In laboratory tests 99% of osteosarcoma (bone cancer) cells were killed off without destroying non-cancerous normal human bone cells. The researchers also incubated the bioactive glasses in a simulated body fluid and after seven days they detected the early stages of bone formation. Gallium is highly toxic, and the researchers found that the ‘greedy’ cancer cells soak it up and self-kill, which prevented the healthy cells from being affected. Their research paper Multifunctional Gallium doped bioactive glasses: a targeted delivery for antineoplastic agents and tissue repair against osteosarcoma has been published in the journal Biomedical Materials. Osteosarcoma is the mostly commonly occurring primary bone cancer and despite the use of chemotherapy and surgery to remove tumours survival rates have not improved much since the 1970s. Survival rates are dramatically reduced for patients who have a recurrence and primary bone cancer patients are more susceptible to bone fractures. Despite extensive research on different types of bioactive glass or ceramics for bone tissue engineering, there is limited research on targeted and controlled release of anti-cancer agents to treat bone cancers. Professor Martin said: “There is an urgent need for improved treatment options and our experiments show significant potential for use in bone cancer applications as part of a multimodal treatment. “We believe that our findings could lead to a treatment that is more effective and localised, reducing side effects, and can even regenerate diseased bones. “When we observed the glasses, we could see the formation of a layer of amorphous calcium phosphate/ hydroxy apatite layer on the surface of the bioactive glass particulates, which indicates bone growth.” The glasses were created in the Aston University labs by rapidly cooling very high temperature molten liquids (1450o C) to form glass. The glasses were then ground and sieved into tiny particles which can then be used for treatment. In previous research the team achieved a 50 percent success rate but although impressive this was not enough to be a potential treatment. The team are now hoping to attract more research funding to conduct trials using gallium. Dr Lucas Souza, research laboratory manager for the Dubrowsky Regenerative Medicine Laboratory at the Royal Orthopaedic Hospital, Birmingham worked on the research with Professor Martin. He added: “The safety and effectiveness of these biomaterials will need to be tested further, but the initial results are really promising. “Treatments for a bone cancer diagnosis remain very limited and there’s still much we don’t understand. Research like this is vital to support in the development of new drugs and new methodologies for treatment options.” Notes to Editors Multifunctional Gallium doped bioactive glasses: a targeted delivery for antineoplastic agents and tissue repair against osteosarcoma Shirin B. Hanaei1, Raghavan C. Murugesan1, Lucas Souza1, Juan I.C. Miranda1, Lee Jeys2,3, Ivan B. Wall3, and Richard A. Martin1 1. College of Engineering and Physical Sciences. Aston University, Aston Triangle, Birmingham, B4 7ET, UK 2. Oncology Department, The Royal Orthopaedic Hospital, Birmingham, B31 2AP, UK 3. College of Health and Life Sciences. Aston University, Aston Triangle, Birmingham, B4 7ET, UK DOI 10.1088/1748-605X/ad76f1 About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
