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Improving Care for Black Patients With Heart Failure and Hypertension
ChristianaCare’s Center for Heart & Vascular Health has dramatically improved the clinical outcomes of Black patients living with heart failure and hypertension by using a digital hybrid platform that provides patients with a dedicated health coach to ensure their care plan is followed and treatment goals are achieved. Through this innovative approach, ChristianaCare achieved a significant improvement in the number of Black patients adhering to prescribed doses of guideline-directed medical therapy (GDMT) for heart failure. “At ChristianaCare, we are deeply committed to eliminating disparities and achieving health equity in the communities we serve,” said Kirk Garratt, M.D., medical director of the Center for Heart & Vascular Health. “We are proud that we have been able to significantly improve the health outcomes of our patients, especially addressing health disparities in the Black population for patients with heart failure and hypertension.” Approximately 32% of ChristianaCare’s heart failure patient population identify as Black, which is a higher percentage compared to the Black population nationally (12.4%). Historically, Black Americans have experienced racial disparities in heart failure treatment and experience worse patterns of adherence to guideline-directed medical therapy (GDMT) . Additionally, Black Americans have a 30% greater risk of death from heart disease than white Americans. Combining technology and human-powered guidance This novel approach to care is powered by Story Health, a leading health technology services company. Its digital platform and health coaches have been able to deliver superior outcomes for ChristianaCare’s patients regardless of race. Black patients in particular have made remarkable gains: 6 times improvement on target doses of beta blockers (76%). 7 times improvement on target doses ACE/ARB/ARNIs (54%). 2 times improvement on target doses of MRAs (57%). ChristianaCare was also able to achieve improvement in Black patients taking SGLT2 inhibitors, rising from a 32% baseline to 74%. Despite their vital role in treating heart failure, SGLT2 inhibitors are historically underprescribed and see lower adherence – largely due to affordability challenges, as costs can be $500 per month or more. Helping patients overcome cost barriers is critical, which is why the health coaches directly engage with patients to identify those who may need assistance and will work on their behalf to qualify for prescription assistance programs. “Along with their digital platform, the health coaches from Story Health understand the unique needs of our patients and have helped us create deeper, more accessible relationships with our patients to help improve their health and outcomes,” said Sourin Banerji, M.D., medical director of Advanced Heart Failure and Mechanical Circulatory at ChristianaCare. The health coaches serve as an extension of the clinician to identify and resolve challenges such as medication adherence, lab work coordination, transportation arrangement and even prescription assistance that cause disruptions in a patient’s care journey and lead to negative outcomes. Improved control of hypertension In addition to heart failure patients, ChristianaCare’s collaboration with Story Health supported patients with hypertension, delivering significant reductions in blood pressure for those enrolled regardless of race. Among Black patients specifically, there were significant decreases in average absolute systolic and diastolic blood pressure levels (17 mm Hg and 8 mm Hg, respectively) after 120 days, compared to 8 mm Hg and 5 mm Hg decreases for uncontrolled hypertensives in another digital program after 12 months. As a result of this initial success, ChristianaCare’s Center for Virtual Health is expanding the use of this care model beyond cardiology to support all patients in the population. Many of these patients struggle to manage high blood pressure, and the use of a continuous care program will be an important tool to help with medication management and addressing social barriers. “Health equity is an incredibly important initiative, and we see our mission as critical to helping specialty and primary care providers drive more equitable care,” said Story Health Co-founder and President Nita Sommers. “As an industry leader, ChristianaCare understands that every individual deserves compassionate care that is accessible, so we are honored to be working with its cardiology team and now the Center for Virtual Health to improve the health of patients.” ChristianaCare has been recognized numerous times for high-quality heart care. Among the many achievements are the American College of Cardiology HeartCARE National Distinction of Excellence Award for three consecutive years (2020-2023) and being named among Healthgrades top 100 hospitals for heart care in the U.S. for the past two years (2022-2023).
MEDIA RELEASE: CAA Manitoba Survey Reveals Troubling Lack of Travel Insurance Preparedness
A recent member survey conducted by CAA Manitoba has unveiled concerning statistics regarding the lack of travel insurance awareness and preparedness. Despite the financial risks associated with travelling unprotected, the survey found that 38 per cent of members in Manitoba who travel don’t always purchase emergency medical travel insurance, highlighting a potential vulnerability. "In a world of uncertainties, our survey highlights a critical gap in travel preparedness among Manitobans," says Susan Postma, regional manager, CAA Manitoba. "At CAA, we believe in empowering travellers with knowledge so they can explore confidently and securely." The survey also discovered that almost a quarter of respondents (24 per cent) ventured on their last trip outside the province without any form of travel insurance, exposing themselves to potential financial burdens in case of emergencies. CAA Manitoba is launching its inaugural CAA Travel Wise Week In response to these findings, CAA Manitoba is launching its inaugural CAA Travel Wise Week to emphasize the crucial importance of travel insurance education. The campaign aims to inform and educate Manitobans on the risks of inadequate coverage and provide valuable insights into securing appropriate protection for their travel adventures. According to claims data from Orion Travel Insurance, the average cost of a medical claim has increased by 14 per cent since 2019. “Costs associated with everything from an ear infection to the use of an air ambulance have risen over the last few years due to medical inflation, underscoring the continued importance of travel insurance for life’s unexpected complications,” says Postma. As part of the CAA Travel Wise Week, CAA Manitoba has curated a list of the top ten tips to help individuals stay protected against common travel concerns: Top 10 Tips for Travel Protection: Make sure all your documentation is in order before you book. It is recommended passport renewals be completed six months before your planned trip. Your passport should still be valid six months after your travel date, as this is required in several countries. Read up on Government of Canada travel advisories for your destination. Understand the risk level associated with travel to a particular destination by checking the Government of Canada Travel Advice and Advisories website. Individual travel advisories remain on a country-by-country basis. Speak with your physician to discuss your travel plans. Speak to your physician to ensure you are up to date with needed travel vaccines and have them prescribe enough medication for the length of your trip. Ensure all the medication you take is packed in your carry-on and in its original bottles with labels intact. Consider purchasing travel insurance at the time of booking your trip. To lock in the best protection, book your travel insurance at the same time you book your trip. Doing so will give you the peace of mind that both you and your investment are protected. Insurance must be in place before things go wrong for you to benefit from coverage. Know the cancellation policies for everything you booked. Make sure you understand any key dates related to cancellation and changes, this includes accommodation, flights, car rentals, tours, cruises. Get to the airport early. CAA recommends arriving at the airport at least two hours before domestic flight departures and at least three for international flights. Check limits or restrictions. Travel insurance is often touted as a perk for certain credit cards but can be drastically limited to both benefits and the sum insured. Check limits or age restrictions on credit cards, employee benefits, and pensions to determine if you need additional travel insurance coverage. Stay connected. It is important to have access to trusted, up-to-date information while travelling so you can monitor changing conditions and requirements and adapt accordingly. Bookmark the Global Affairs Canada website prior to departure and check it regularly while abroad. It is also a good idea to sign up for Registration of Canadians Abroad. Find these and more information at www.caamanitoba.com/travel Note emergency contact numbers. Provide your travel agent with contact details while travelling abroad and keep all important phone numbers handy; this includes how to call for help and your travel insurance assistance phone number. Protect your ID. Make sure you have a digital version and paper version of your travel insurance wallet card, tickets to various events and attractions and even your passport. You may also want to leave a copy of important paperwork with family members or friends. For more information, visit www.caamanitoba.com/travelwise The survey was an online quantitative survey done with the CAA Members Matter Panel in Manitoba between September 22 - 29, 2023. The margin of error for a sample of this size is plus or minus 4.0% at the 95% confidence level.
MEDIA RELEASE: CAA Survey Reveals Troubling Lack of Travel Insurance Preparedness
A recent member survey conducted by CAA South Central Ontario (CAA SCO) has unveiled concerning statistics regarding the lack of travel insurance awareness and preparedness. Despite the financial risks associated with travelling unprotected, the survey found that 40 per cent of members in Ontario who travel don’t always purchase emergency medical travel insurance, highlighting a potential vulnerability. "In a world of uncertainties, our survey highlights a critical gap in travel preparedness among Ontarians," says Kaitlynn Furse, director of corporate communications at CAA SCO. "At CAA, we believe in empowering travellers with knowledge so they can explore confidently and securely." The survey also discovered that almost a quarter of respondents (23 per cent) ventured on their last trip outside the province without any form of travel insurance, exposing themselves to potential financial burdens in case of emergencies. Additionally, 33 per cent of people who travel with travel insurance relied on the coverage provided by their credit cards, raising concerns about coverage limitations, especially for those over 65. CAA SCO is launching its inaugural CAA Travel Wise Week In response to these findings, CAA SCO is launching its inaugural CAA Travel Wise Week to emphasize the crucial importance of travel insurance education. The campaign aims to inform and educate Ontarians on the risks associated with inadequate coverage and provide valuable insights into securing appropriate protection for their travel adventures. According to claims data from Orion Travel Insurance, the average cost of a medical claim has increased by 14 per cent since 2019. “Costs associated with everything from an ear infection to the use of an air ambulance have risen over the last few years due to medical inflation, underscoring the continued importance of travel insurance for life’s unexpected complications,” says Furse. As part of CAA Travel Wise Week, CAA SCO has curated a list of the top ten tips to help individuals stay protected against common travel concerns: Top 10 Tips for Travel Protection: Make sure all your documentation is in order before you book. It is recommended passport renewals be completed six months before your planned trip. Your passport should still be valid six months after your travel date, as this is required in several countries. Read up on Government of Canada travel advisories for your destination. Understand the risk level associated with travel to a particular destination by checking the Government of Canada Travel Advice and Advisories website. Individual travel advisories remain on a country-by-country basis. Speak with your physician to discuss your travel plans. Speak to your physician to ensure you are up to date with needed travel vaccines and have them prescribe enough medication for the length of your trip. Ensure all the medication you take is packed in your carry-on and in its original bottles with labels intact. Consider purchasing travel insurance at the time of booking your trip. To lock in the best protection, book your travel insurance at the same time you book your trip. Doing so will give you the peace of mind that both you and your investment are protected. Insurance must be in place before things go wrong for you to benefit from coverage. Know the cancellation policies for everything you booked. Make sure you understand any key dates related to cancellation and changes, this includes accommodation, flights, car rentals, tours, cruises. Get to the airport early. CAA recommends arriving at the airport at least two hours before domestic flight departures and at least three for international flights. Check limits or restrictions. Travel insurance is often touted as a perk for certain credit cards but can be drastically limited to both benefits and the sum insured. Check limits or age restrictions on credit cards, employee benefits, and pensions to determine if you need additional travel insurance coverage. Stay connected. It is important to have access to trusted, up-to-date information while travelling so you can monitor changing conditions and requirements and adapt accordingly. Bookmark the Global Affairs Canada website prior to departure and check it regularly while abroad. It is also a good idea to sign up for Registration of Canadians Abroad. Find these and more information at www.caasco.com/travel. Note emergency contact numbers. Provide your travel agent with contact details while travelling abroad and keep all important phone numbers handy; this includes how to call for help and your travel insurance assistance phone number. Protect your ID. Make sure you have a digital version and paper version of your travel insurance wallet card, tickets to various events and attractions and even your passport. You may also want to leave a copy of important paperwork with family members or friends. For more information, visit www.caasco.com/travelwise The survey was an online quantitative survey done with the CAA Members Matter Panel in Ontario between September 22 - 29, 2023. The margin of error for a sample of this size is plus or minus 1.6% at the 95% confidence level.
New Aston University spin-out company will develop novel ways to treat non-healing wounds
EVolution Therapeutics (EVo) has been founded on the work of Professor Andrew Devitt into the causes of inflammatory disease A failure to control inflammation in the body, usually a natural defence mechanism, can cause chronic inflammation, such as non-healing wounds Non-healing wounds cost the NHS £5.6bn annually, so there is a vital need for new treatments. Aston University’s Professor Andrew Devitt, Dr Ivana Milic and Dr James Gavin have launched a new spin-out company to develop revolutionary treatments to treat chronic inflammation in patients. One of the most common inflammatory conditions is non-healing wounds, such as diabetic foot ulcers, which cost the NHS £5.6bn annually, the same cost as managing obesity. Such wounds are generally just dressed, but clinicians say there is a vital need for active wound treatments, rather than passive management. The spin-out, Evolution Therapeutics (EVo), will aim to create these vital active treatments. Inflammation in the human body helps to fight infection and repair damage following injury and occurs when the immune system floods the area with immune cells. Normally, this inflammation subsides as the damage heals, with the immune system signalling to the immune cells to leave. However, in some cases, the usual healing mechanism is not triggered and the inflammatory response is not turned off, leading to chronic inflammation and so-called inflammatory diseases. EVo is based on Professor Devitt’s work on dying cells in the body, known as apoptotic cells, and how they contribute to health. Dying cells release small, membrane-enclosed fragments called extracellular vesicles (EVs), which alert the immune system to the death of cells, and then trigger the body’s natural repair mechanism and remove the dead cells. It is estimated that 1m cells die every second. Professor Devitt and his team have identified the molecules within the EVs which control the healing process and are engineering new EVs loaded with novel healing enzymes, to drive the body’s repair responses to actively heal wounds. Much of the research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC) with additional support from the Dunhill Medical Trust. Professor Devitt, Dr Milic and Dr Gavin received Innovation-to-Commercialisation of University Research (ICURe) follow-on funding of £284,000 to develop the vesicle-based therapy with EVo. Most recently, in December 2023, Professor Devitt and Dr Milic were awarded £585,000 from the BBSRC Super Follow-on-Fund to develop engineered cells as a source of membrane vesicles carrying inflammation controlling cargo. The team, together with Professor Paul Topham, also received funding from the National Engineering Biology Programme (£237,000) to support polymer delivery systems for vesicles. EVo is one of the 12 projects being supported by SPARK The Midlands, a network which aims to bridge the gap between medical research discoveries of novel therapeutics, medical devices and diagnostics, and real-world clinical use. SPARK The Midlands is hosted at Aston University, supported by the West Midlands Health Tech Innovation Accelerator (WMHTIA), and was launched at an event on 31 January 2024. Professor Devitt, EVo chief technical officer, said: “Inflammation is the major driver of almost all disease with a huge contribution to those unwelcome consequences of ageing. We are now at a most exciting time in our science where we can harness all the learning from our research to develop targeted and active therapies for these chronic inflammatory conditions.” Dr Gavin, EVo CEO, said: “The chronic inflammation that results in non-healing wounds are a huge health burden to individuals affecting quality of life as we age but also to the economy. Our approach at EVo is to target the burden of non-healing wounds directly to provide completely novel approaches to wound care treatment. By developing a therapy which actively accelerates wound healing, we hope to drastically improve quality of life for patients, whilst reducing the high cost attached to long term treatment for healthcare systems worldwide.”
Coping with Grief During the Holiday Season
Baylor experts suggest three strategies to help cope with grief during the holidays (Image Credit: D-Keine/Getty Images) The holidays are typically a time of joy and celebration for most people, but this time of year can be very different for grieving people. The death of a loved one can be especially hard during the holidays as they are full of memories, traditions, and sensations associated with the holidays – all reminders that this year is different, and someone is no longer here. What can someone in the midst of grief do to make this time more positive and step toward emotional healing? William (Bill) G. Hoy, D.Min, FT., clinical professor and associate director of Medical Humanities, and Candi Cann, Ph.D., associate professor of religion in the Honors College at Baylor, suggest three strategies for grieving people to cope with their loss during the holidays. “Holidays are also hard in grief because they are built around relationships,” Hoy said. “Family gatherings cannot ever be the same, and, of course, memories of bad relationships cause us to realize the past cannot be changed.” Acknowledge your pain The first step is to admit the pain of grieving. “Saying goodbye to a loved one is no easy task, and, undoubtedly, it feels different than you could ever have expected,” said Hoy. Cann pointed out that some deaths bring about complicated grief if the loss is from a difficult relationship. “It is okay to feel relief in addition to grief and it is important to validate all of your feelings – it’s a complicated grief because it was a complicated relationship.” Hoy said that culturally people tend to try to get around the pain without facing it, which only makes it harder later on. “There is an empty chair at the table on this special occasion. The grief following a death assault at every turn with the reality that they will not be returning to the table. Because holiday grief is so painful, there is no need to try to escape the pain this holiday season.” Take care of yourself Self-care is vital during this time, said Cann. She encourages grieving people to stay active, eat healthy, go outside to be in nature and get enough sleep. “It’s totally normal to need more sleep when you're depressed and grieving, you just have to be gracious with yourself about that,” she said. Hoy added, “Remember that grief is very tiring and - even under the best of circumstances - holidays are very taxing.” Give yourself permission to turn down invitations or leave parties early. In addition to taking care of your physical health, Cann recommends staying engaged in your community or church. “Being in community with others is very beneficial for your mental health.” At the same time, be honest with yourself about what you want to do and only accept invitations or participate in activities that you feel you can handle, said Hoy. Evaluate traditions and embrace memories When the holidays arrive, many people want to change everything about the holidays to avoid the sad feelings, said Hoy. Both he and Cann suggest evaluating family traditions, choosing those traditions that are most important to continue and including the dead through new traditions. “Don't forget to embrace your memories of past holidays and special events as you face this season,” Hoy said. “We cannot have things like they were, but we can hold in our hearts the memories of days gone by. You may want to light a special candle or purchase a special holiday decoration and hang it in your loved one's memory.” “A lot of people feel like when that person is gone, the love is gone too, but the love is still there,” Cann said. “You wouldn't feel the grief or the big hole that you now have if you didn't have all of this love in the first place.” She suggests embracing their presence by including a place at the table for Christmas dinner, making their favorite recipe or many other ways to continue the bonds and positively remember the dead in your life. By doing these things, “you're including them in your conversation, and you're making space for that person, both literally and symbolically.” How to support someone who is grieving Being supportive of someone grieving requires patience and vulnerability. “Engage with the person and ask how you can best support them,” Cann said. “And let them know that you are thinking about them during this time.” “A lot of people don't want to bring it up because they don't want to make people sad at a joyful time,” Cann said. “But the point is, they already are sad, so bringing it up allows them to express it” and feel accepted in their pain. Hoy said to remember that there is no set timeline for an individual grief journey. It is also important to remember that not all grief is related to death. There are many types of loss that people experience such as divorce or disease. We can’t decide or predict what defines another person's grief, but we can offer love and support. Approaching the holidays when experiencing grief over the death of someone or a deep loss may be painful at first, but using these strategies can help us face the future by celebrating with gratitude what we had in the past.
ChristianaCare Opens Three New School-Based Health Centers in Delaware Elementary Schools
To address health concerns when they are at their earliest, most preventable stages, ChristianaCare has opened three new school-based health centers in Delaware elementary schools: Brookside Elementary School in Newark – part of the Christina School District. Silver Lake Elementary School in Middletown – part of the Appoquinimink School District. Richardson Park Elementary School in Wilmington – part of the Red Clay School District. “At ChristianaCare, we recognize that early intervention is vital in order to address the comprehensive health needs of adolescents in our community,” said Erin Booker, chief bio-psycho-social officer at ChristianaCare. “Childhood trauma hurts the ability of children to learn and increases their risk of chronic disease and mental health issues. Through the opening of these three new school-based health centers, these children now have convenient access to medical services, behavioral health services and wraparound social care. These centers can improve their health and education and set them on a lifelong path of wellness.” These new elementary school Wellness Centers are a partnership between ChristianaCare, the Delaware School-Based Health Alliance, the schools and school districts, supported by New Castle County government with funds from the American Rescue Plan Act. With the latest additions, ChristianaCare now operates school-based health centers in seven elementary schools and 19 high schools and middle schools. Each ChristianaCare school-based health center includes a health care team of medical, mental health, community health and nutrition experts. The health centers also provide a host of services by appointment during the school day. A parent or guardian must provide a signed permission form prior to a student’s first visit to a health center. Priscilla Michelle Mpasi, M.D., FAAP speaks at the ribbon-cutting at Richardson Park Elementary School. “At ChristianaCare, we serve together, guided by our values of love and excellence, and that mission of service is why we are committed to improving the health and wellbeing of the community,” said Priscilla Michelle Mpasi, M.D., FAAP, assistant medical director for the Clinically Integrated Network and Delaware Medicaid Partners. “School-based health centers are the connection of whole-child health and education. As we all know, early intervention is the key to wellness. Children can learn better when they are happy and healthy and know they have a safe place to go when they need care.” At no cost to the students, and located within each elementary school, the three school-based health centers also alleviate the need for parents and students to find transportation to address their health care needs. “Ensuring that our students are prepared to learn is crucial, but it can be challenging when they are dealing with various obstacles,” said Dan Shelton, Ed.D., superintendent of Christina School District. “That’s why our collaboration with ChristianaCare and New Castle County presents an incredible opportunity to bring essential services directly to our school. By establishing an in-school wellness center at Brookside Elementary School, we are thrilled to provide our students with the support they need to be fully prepared and eager to learn.” “Empowering our future starts with nurturing the health and well-being of our youngest minds,” said Dorrell Green, Ed.D., superintendent of the Red Clay Consolidated School District, which oversees the new school-based health center at Richardson Park. “Elementary school-based health centers play a pivotal role in fostering a thriving community by providing accessible, comprehensive healthcare, ensuring every child has the opportunity to learn, grow, and succeed.” “We are so grateful to open the first school-based health center at an elementary school in Appoquinimink School District,” said Matt Burrows, superintendent of the Appoquinimink School District. “This wouldn’t be possible without the partnership of New Castle County Government and the Delaware School-Based Health Alliance. The services provided by school-based health centers span a large array of care – including physicals, vaccinations, mental health, and more. As fast as our community is growing here in the MOT area, we know access to health care can be a challenge for many of our families. Having these services inside one of our elementary schools will be incredibly helpful for our families. The services that are being provided by ChristianaCare are invaluable for our students and their families.”
Covering King Charles? Our Expert can Help
It's news that has shocked the world and has citizens across Britain and the Commonwealth as well loyal watchers of the British monarchy in deep concern. This week, King Charles was diagnosed with cancer. News was released Monday in a statement from the palalce. This news will raise many questions both in the UK and abroad. Will his medical condition make him consider stepping down? Is William ready to be King? Is there still a time, place and relevance for Royals in these modern times? If you're covering - let our experts help. Dr. Glen Duerr is a citizen of three countries. He was born in the United Kingdom, moved to Canada as a teenager, and then to the United States to obtain his Ph.D. His teaching and research interests comparative politics and international relations theory. Dr. Duerr is available to speak to media regarding this topic– simply click on his icon to arrange an interview.
Since 2022, the U.S. Food and Drug Administration has been actively urging consumers to avoid purchasing or consuming tianeptine -- a synthetic drug commonly called "gas station heroin" that can mimic the actions of opioids like fentanyl. Now, the FDA is upping the urgency of it's warnings as vendors continue to market the drug as a so-called "dietary supplement." UConn's C. Michael White, a Distinguished Professor of Pharmacy Practice, spoke with The Conversation about the problem with tianeptine in a must-read Q-and-A: What is tianeptine and why is it risky? Tianeptine stimulates the same receptors as well-known opioids such as fentanyl, heroin and morphine. When these drugs make their way from the blood to the brain, they bind to the “mu” type opioid receptor that triggers the sought-after pain relief and euphoria of those drugs as well as the dangerous effects like slowed or stopped breathing. High doses of tianeptine can bring euphoric effects similar to heroin and can also bring about the dissociative effect – the perception of your mind being disconnected from your surroundings and body – that is reminiscent of ketamine, an anesthetic that has a role in treating post-traumatic stress disorder and depression but has also commonly been abused as a street drug. Products containing tianeptine are often called “legal high drugs” – sometimes dubbed “gas station drugs” – a term used for all non-FDA-approved synthetic drugs that are sold casually in gas stations, online and elsewhere. What are the major adverse effects that people can experience? Data from clinical trials, case reports and poison control centers shows that tianeptine commonly induces agitation. This is typically accompanied by a fast heart rate and high blood pressure, confusion, nightmares, drowsiness, dry mouth and nausea, among other conditions. The most serious adverse events are slowed or stopped breathing, coma, heart arrhythmia and death. When long-term users try to stop tianeptine use, they often experience withdrawal symptoms reminiscent of opioid withdrawal. Consumers need to be aware that products containing tianeptine may not adhere to good manufacturing practices. This means they could contain lead or have other heavy metal contamination or be contaminated by microorganisms such as salmonella or mold. They could also contain other drug ingredients that are not disclosed. Knowingly or unknowingly combining active ingredients can increase the risk of adverse events. Additionally, the amount of the active ingredient contained in the product can vary widely, even with the same manufacturer. So past use does not guarantee that using the same amount will provide the same effect. How are these drugs sold in the US if they are not FDA-approved? If a drug product is not FDA-approved for prescription or over-the-counter-use, it is the Drug Enforcement Agency that is responsible for controlling market access. Before the DEA can ban an active ingredient in a drug product, it must be designated Schedule I, meaning the drug has no legitimate medical purpose and has high abuse potential. Manufacturers do not have to alert the DEA before selling their products to U.S. citizens. This means the DEA must detect an issue, identify the products causing the issue, identify the active ingredients in the product in question and do a full scientific review before designating it as Schedule I. Tianeptine came to market masquerading as a dietary supplement in gas stations and smoke shops, even though it is a synthetic compound. Tianeptine is also sold online allegedly for research purposes and not for human consumption. Tianeptine is undergoing clinical trials for the treatment of pain and depression, but sellers do nothing to make this type of labeling clear to consumers or to restrict purchases to researchers. What can people do to protect themselves and their families? Non-FDA-approved products containing synthetic drugs are very risky to use and should be avoided. FDA-approved drugs are available by a prescription from a health professional or over the counter with active ingredients on an approved list. If someone in a gas station, smoke shop or over the internet touts the benefits of a non-FDA-approved drug product – for pain or anxiety relief, to increase energy or for a buzz – be aware. It could be dangerous the first time you use it, but using it successfully once also doesn’t mean the experience will be the same the next time, and continued use can cause addiction. If a product is being sold “not for human consumption” or “for research purposes only,” you are at a high risk if you take it. Before you take any dietary supplement, make sure you check the active ingredient to be sure that it is, in fact, a natural product and not a synthetic chemical. If someone you know has bags with unmarked powder, a product labeled for research use or not for human consumption, or tablets or capsules not in standard drug bottles, that is a sign of a potentially dangerous situation. Standard drug tests sold over the counter are not designed to pick up tianeptine. One of the main reasons that people use these alternative substances of abuse over regular opioids, cannabis or amphetamines is that they are much harder to detect through work- or at-home drug screens by parents, schools, employers, probation officers and so on. If the DEA is not responding to emerging threats quickly enough, individual states can also act to ban sales of dangerous active ingredients in products. As of January 2024, at least 12 states have banned the sale of tianeptine, according to the FDA, although people in those states can still illegally procure it from the internet. So contacting your state legislators could be a place to start exercising your power to help prevent the harms from these products. This is an important piece, and if you are looking to know about tianeptine and the threat it poses to consumers in America, then let us help. Dr. C. Michael White is an expert in the areas of comparative effectiveness and preventing adverse events from drugs, devices, dietary supplements, and illicit substances. Dr. White is available to speak with media -- click on his icon now to arrange an interview today.
Aston University AI project aims to make international health data sharing easier
Project to improve sharing data while complying with general data protection regulation (GDPR) guidelines Aston Institute of Photonic Technologies awarded almost £300k to work on European-wide project Will develop secure data sharing system to allow access to large sets of multi-source health data via tailor-made AI tools. Aston University is to explore the use of AI to improve sharing health data internationally. Dr Sergei Sokolovski of the University’s Aston Institute of Photonic Technologies has been awarded €317,500 to work on a European-wide project. Called BETTER (Better real-world health data distributed analytics research platform) the spans16 academic, medical and industrial partners. Although data-driven medicine is currently used to improve diagnosis, treatment and medical research ethical, legal and privacy issues can prevent sharing and centralising data for analysis. The research at Aston University’s involvement in the BETTER project aims to overcome these challenges so health data can be shared across national borders while fully complying with the general data protection regulation (GDPR) guidelines. Dr Sergei Sokolovski will lead the development of a secure data sharing system which will allow access to large sets of multi-source health data via tailor-made AI tools. Scientists and healthcare professionals will be able to compare, integrate and analyse data securely at a lower cost than current methods to improve people’s health. The BETTER project will focus on three health conditions; childhood learning disabilities, inherited degenerative retina diseases and autism, involving seven medical centres across the European Union and beyond. Dr Sergei Sokolovski said: “Data protection regulations prohibit data centralisation for analysis purposes because of privacy risks like the accidental disclosure of personal data to third parties. “Therefore, to enable health data sharing across national borders and to fully comply with GDPR guidelines this project proposes a robust decentralised infrastructure which will empower researchers, innovators and healthcare professionals to exploit the full potential of larger sets of multi-source health data. “As healthcare continues to evolve in an increasingly data-driven world projects like BETTER offer promising solutions to the challenges of health data sharing, research collaboration, and ultimately, improving the well-being of citizens worldwide. “The collaboration between multiple stakeholders, including medical centres, researchers, and innovators, highlights the importance of interdisciplinary efforts in addressing these complex issues.” The research will last 42 months. ENDS Better Real-World Health-Data Distributed Analytics Research Platform, Grant agreement 101136262 https://www.better-health-project.eu/ Research Universities taking part are: Aston University, Klinikum der Universitaet zu Koeln, Universiteit Maastricht, Universitat Politecnica de Valencia, Universitetet i Tromsoe, About Aston University Founded in 1895 and a university since 1966, Aston University is a long-established university led by its three main beneficiary groups – students, business and the professions, and the West Midlands region and wider society. Located in Birmingham at the heart of a vibrant city, the campus houses all the University’s academic, social and accommodation facilities for our students. Professor Aleks Subic is the Vice-Chancellor & Chief Executive. In 2022 Aston University was ranked in the top 25 of the Guardian University Guide, based on measures including entry standards, student satisfaction, research quality and graduate prospects. The Aston Business School MBA programme was ranked in the top 100 in the world in the Economist MBA 2021 ranking. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Reinventing the laser diode: free public lecture by Professor Richard Hogg
Professor Richard Hogg joined Aston University in spring 2023 His inaugural lecture is about laser diodes, the tiny components that are a vital part of everyday life The free event will take place on Tuesday 28 November. The latest inaugural lecture at Aston University will explore the laser diode and what’s in store for it in the future. Professor Richard Hogg will explain how his future research might make laser diodes do some of the things that they currently can’t do. The laser diode turned 61 years old this month and the tiny components are a critical part of everyday life. Professor Hogg said: “They are now at the heart of the continuous transformation of society. “They transmit data to allow instantaneous, ubiquitous communication and data access. “They allow light to be used for cutting and welding, for sensing and imaging, for displays and illumination, and data storage. “And in the guise of a laser pointer they can even be used to entertain your cat!” He will discuss different classes of laser diode and their operation and applications. Professor Hogg joined Aston University in spring 2023 and is based at Aston Institute of Photonic Technologies (AIPT). It is one of the world’s leading photonics research centres and its scientific achievements range from medical lasers and bio-sensing for healthcare, to the high-speed optical communications technology that underpins the internet and the digital economy. The professor is also chief technology officer at III-V Epi, which provides compound semiconductor wafer foundry services. The free event will take place on the University campus at Conference Aston, on Tuesday 28 November from 6pm to 8pm and will be followed by a drinks reception. It can also be viewed online. To sign up for a place in person visit https://www.eventbrite.co.uk/e/717822585677?aff=oddtdtcreator To sign up for a place online visit https://www.eventbrite.co.uk/e/717824260687?aff=oddtdtcreator