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Record-breaking heatwaves are plaguing the U.S. this summer, making it difficult to stay cool. However, the scorching temperatures aren't just affecting us at the ground level — they're disrupting air travel, too, with increasing flight delays and aircraft weight restrictions. Visiting assistant professor of aeronautics Shem Malmquist, a recognized expert in aviation safety and operations, spoke with FOX 35 Orlando about how extreme temperatures can directly impact aircraft performance, particularly at high-traffic airports during the summer. "Temperatures are probably not something people think about," said Shem Malmquist, a graduate lecturer in aviation at Florida Tech. "But the delays just compound on each other. If you start getting delayed because people need more time to take breaks to stay cool, now that flight’s late, and that has a snowball effect." These limitations can affect passenger loads, cargo capacity and overall flight scheduling. As temperatures continue to climb, Malmquist warned that these disruptions could become the new normal — not just a seasonal inconvenience, but a growing challenge for the aviation industry in the face of climate change. A seasoned Boeing 777 captain and accident investigator, Malmquist has spent decades researching aircraft operations and emergency scenarios. He’s also contributed to global conversations on aviation safety policy and climate-related infrastructure resilience. If you’re covering this topic or looking to speak with an expert on the intersection of climate and air travel, Malmquist is available for interviews. Click the icon below to connect with him.
ChristianaCare and Children’s Hospital of Philadelphia (CHOP) today announce a new strategic affiliation to expand access to world-class pediatric care in Delaware and surrounding communities. The collaboration, which is expected to begin in spring 2026, will enhance access to specialized pediatric care by bringing CHOP’s renowned expertise closer to home for families in the communities ChristianaCare serves in Delaware, Maryland, Pennsylvania and New Jersey. By integrating CHOP’s services with ChristianaCare’s established network, the collaboration will improve care delivery, making advanced pediatric treatments more accessible and reducing the need for families to travel long distances for care. A Bold Step Forward in Pediatric Care “This collaboration brings together two amazing organizations that are already nationally recognized for clinical excellence—and we’re going to be even better together,” said Janice E. Nevin, M.D., MPH, president and CEO of ChristianaCare. “Our affiliation with CHOP marks a bold step forward in our mission to provide the highest quality care to children and families across the communities we serve. These are uncertain times for many parents with young children in need of routine or complex medical care. ChristianaCare and CHOP are joining forces to provide world-class care, close to home, at a time when it’s needed most.” “Bringing seamless, family-centered care to our patients is a priority at Children’s Hospital of Philadelphia,” said Madeline Bell, CEO at Children’s Hospital of Philadelphia. “As one of the region’s most dynamic health systems, ChristianaCare has earned a national reputation for its bold approaches to both clinical care and innovation. Our new affiliation is driven by a shared vision: redefining what is possible in health care and ensuring that every patient — at every stage of life — receives the highest standards of care, from infancy through adulthood.” “Our team at ChristianaCare is excited to work closely with Children’s Hospital of Philadelphia to bring even more specialized care to our community,” said Megan Mickley, M.D., chair of Pediatrics at ChristianaCare. “CHOP’s leadership in pediatric medicine will complement the outstanding care already provided at ChristianaCare, ensuring that our youngest patients receive the most advanced treatments in a compassionate and supportive environment.” Initial Focus and Future Growth This affiliation between ChristianaCare and CHOP represents a significant increase in access to world-class pediatric care for communities in Delaware, Maryland, southeast Pennsylvania and southern New Jersey. CHOP, a global leader in pediatric care and research for over 165 years, is consistently ranked among the top children’s hospitals in the country, known for pioneering breakthroughs across a breadth of pediatric care areas. The affiliation will include all ChristianaCare hospitals and locations where pediatric emergency and inpatients are cared for. The collaboration will initially focus on pediatric and neonatal services. Patients at ChristianaCare will have access to CHOP’s expertise in rare and complex diseases and a wide range of newborn and pediatric services, including surgery, cardiology, neurology, radiology, ophthalmology and genetics, as well as educational and research opportunities. As the collaboration grows, it will explore further opportunities to expand pediatric care and improve health care delivery in the region.
Are China's New Policies Opening Up China?
For centuries China has been known as a closed country. When the Ming Dynasty (1368-1644) started enforcing immense cultural and political influence, it acted as a catalyst for China's closed country status. Then the Qing dynasty (1644-1912) made the closed country status official by expanding China's political, cultural and administrative structures. Now after over 600 years, China is announcing they may become more open than they have in past centuries. China is not fully becoming open, but there are two ways China is hoping to re-establish its reputation among other countries. In 2024 China announced they are enabling a temporary visa-free policy, that permits visitors from 43 countries to visit China without visas for short trips lasting only a few days. China installed this policy with hopes of promoting global goodwill and to encourage tourism and business travel. Now in 2025, China says they will implement policies that will promote stable foreign trade growth and improve services for enterprises. While this new policy is just beginning, the visa-free policy will end at the end of 2025. So, while China says they are becoming more open, they mean they are welcoming foreign businesses and investors. They are currently not becoming open religiously, politically, socially or economically. Citizens, even visitors, still remain under strict censorship, surveillance and political control. These policies also don't mean that foreign companies will no longer experience restrictions, forced partnerships with Chinese firms, data rules, and unexpected regulatory pressure. These things will still continue to occur. China is being selective on what these policies entail and how long they will last. Since the COVID lockdowns and now with the real estate crashes and youth unemployment, China has felt its economy slowing. It's their hope that these new policies will help boost China's economy. Economic Perspective: Dr. Jared Pincin is an expert on economics and is available to speak to media regarding China's economy – simply click on his icon or email mweinstein@cedarville.edu to arrange an interview. International Relations Perspective: Dr. Glen Duerr, professor of international studies at Cedarville University and a citizen of the United Kingdom, Canada, and the United States, is a nationally known expert on this subject and is available to speak to on China's new policies. To schedule an interview, email Mark D. Weinstein, executive director of public relations at Cedarville University at mweinstein@cedarville.edu or click on his icon.
School will soon be out for the summer, and many young families are opting to explore the beauty of their own country, travelling to top destinations like Toronto, Vancouver, and Halifax rather than heading south. While many travellers prioritize insurance for international trips, a recent CAA survey found that many people overlook the necessity of travel insurance for domestic travel, often assuming provincial healthcare will have them covered. "Exploring Canada’s breathtaking landscapes is an adventure worth taking, but unexpected travel hiccups don’t stop at the border,” says Susan Postma, regional manager, CAA Manitoba. “Whether it’s a sudden medical emergency or trip disruptions, having the right travel insurance ensures you can focus on making memories." A new national travel survey conducted for CAA reveals that nearly four in ten Canadians (39 per cent) travelled outside their home province without any form of travel insurance during their last trip. Some believed it was unnecessary (45 per cent), others worried about the cost (22 per cent), and 19 per cent took their chances, hoping nothing would go wrong. The reality? Provincial health insurance programs typically cover only basic emergency medical services when travelling in another province. “Many Canadians assume they’re fully protected when travelling within the country, but that’s simply not the case,” says Postma “A minor mishap can become a major expense, whether a broken ankle on a hike or a last-minute interruption.” Here are two unexpected ways travel insurance can help: You break your ankle while hiking on one of Canada’s beautiful nature trails and now need an ambulance or an airlift, crutches, and medication. You’re on vacation but must return unexpectedly because someone at home gets seriously ill. In stressful situations, like when a family member falls ill, it helps to have support when you need it. Trip Cancellation Insurance would cover the flight change fee and help get you back home. According to Orion Travel Insurance, part of the CAA family, the average medical claim cost has risen by 15 per cent annually since 2019, with everything from ear infections to air ambulance services becoming significantly more expensive. Here are ten additional tips to help your trip go smoothly, no matter where you travel. Know the cancellation policies and check limits or restrictions for everything you booked. Make sure you understand any key dates related to cancellations or changes. This includes accommodation, flights, car rentals, tours, and cruises. Check limits or restrictions on credit cards, employee benefits, and pensions to determine if you need additional travel insurance coverage. Make sure all your documentation is in order before you book. It is recommended that passport renewals be completed six months before your planned trip. Your passport should still be valid six months after your travel date, as this is required in several countries. There are varying documentation requirements, so make sure you fully understand what information you need to have ready and in what format. Read up on Government of Canada travel advisories for your destination. Understand the risk level associated with travel to a particular destination by checking the Government of Canada Travel Advice and Advisories website. Individual travel advisories remain on a country-by-country basis. It is important that Ontarians/Manitobans understand the ongoing uncertainty associated with international travel. Speak with your physician to discuss your travel plans. It is important that you speak to your physician to ensure you are up to date with needed travel vaccines and have them prescribe enough medication for the length of your trip. Ensure all the medication you take is packed in your carry-on and in its original bottles with labels intact. Consider purchasing travel insurance at the time of booking your trip. To lock in the best protection, book your travel insurance at the same time you book your trip. Booking Trip Cancellation or Interruption insurance will give you peace of mind that you and your investment are protected. Insurance must be in place before things go wrong for you to benefit from coverage. Get to the airport early. The old standby of being at the airport one hour before takeoff for domestic flights and two hours before international flights no longer apply. CAA recommends arriving at the airport at least two hours before domestic flight departures and at least three for international flights. Stay connected. It is important to have access to trusted, up-to-date information while travelling so you can monitor changing conditions and requirements and adapt accordingly. Bookmark the Global Affairs Canada website before departure and check it regularly while abroad. It is also a good idea to sign up for Registration of Canadians Abroad and stay in touch with a family or friend who knows your travel plans. Find these and more information at caamanitoba.com/travelwise Note emergency contact numbers. Provide your travel agent with contact details while travelling abroad and keep all important phone numbers handy; this includes how to call for help and your travel insurance assistance phone number. It is also a good idea to keep a physical copy of all their reservation information and leave those details with a friend or family member. Protect your ID. Ensure you have a digital and paper version of your Travel insurance wallet card, tickets to various events and attractions, and even your passport. You may also want to leave a copy of the necessary paperwork with family members or friends. Pack your carry-on wisely. Include the most important items, such as your passport/ID, boarding pass, travel itinerary, wallet, phone, charger, medications, toiletries, glasses/contacts, noise-canceling headphones, book/e-reader, snacks, empty water bottle, travel pillow, change of clothes, sweater, socks, pen, and reusable bags, in your carry-on bag. For more information on travel insurance and how to stay protected, visit caamanitoba.com/travelwise Based on the sample size of n=2,005 and with a confidence level of 95%, the margin of error for this research is +/- 2%.)
School will soon be out for the summer, and many young families are opting to explore the beauty of their own country travelling to top destinations like Vancouver, Calgary and Halifax rather than heading south. While many travellers prioritize insurance for international trips, a recent CAA survey found that many people overlook the necessity of travel insurance for domestic travel, often assuming provincial healthcare will have them covered. "Exploring Canada’s breathtaking landscapes is an adventure worth taking, but unexpected travel hiccups don’t stop at the border,” says Kaitlynn Furse, Director Corporate Communications, CAA SCO. “Whether it’s a sudden medical emergency or trip disruptions, having the right travel insurance ensures you can focus on making memories." The national travel survey conducted for CAA reveals that four in ten Ontarians (41 per cent) travelled outside their home province without travel insurance during their last trip. Some believed it was unnecessary (43 per cent), others worried about the cost (24 per cent), and 20 per cent took their chances, hoping nothing would go wrong. “Many Canadians assume they’re fully protected when travelling within the country, but that’s simply not the case,” adds Furse. A minor mishap can become a major expense, whether a broken ankle on a hike or a last-minute interruption.” Here are two unexpected ways travel insurance can help: You break your ankle while hiking on one of Canada’s beautiful nature trails and now need an ambulance or an airlift, crutches, and medication. You’re on vacation but must return unexpectedly because someone at home gets seriously ill. In stressful situations, like when a family member falls ill, it helps to have support when you need it. Trip Cancellation Insurance would cover the flight change fee and help get you back home. According to Orion Travel Insurance, part of the CAA family, the average medical claim cost has risen by 15 per cent annually since 2019, with everything from ear infections to air ambulance services becoming significantly more expensive. Here are ten additional tips to help your trip go smoothly, no matter where you travel. Know the cancellation policies and check limits or restrictions for everything you booked. Make sure you understand any key dates related to cancellations or changes. This includes accommodation, flights, car rentals, tours, and cruises. Check limits or restrictions on credit cards, employee benefits, and pensions to determine if you need additional travel insurance coverage. Make sure all your documentation is in order before you book. It is recommended that passport renewals be completed six months before your planned trip. Your passport should still be valid six months after your travel date, as this is required in several countries. There are varying documentation requirements, so make sure you fully understand what information you need to have ready and in what format. Read up on Government of Canada travel advisories for your destination. Understand the risk level associated with travel to a particular destination by checking the Government of Canada Travel Advice and Advisories website. Individual travel advisories remain on a country-by-country basis. It is important that Ontarians/Manitobans understand the ongoing uncertainty associated with international travel. Speak with your physician to discuss your travel plans. It is important that you speak to your physician to ensure you are up to date with needed travel vaccines and have them prescribe enough medication for the length of your trip. Ensure all the medication you take is packed in your carry-on and in its original bottles with labels intact. Consider purchasing travel insurance at the time of booking your trip. To lock in the best protection, book your travel insurance at the same time you book your trip. Booking Trip Cancellation or Interruption insurance will give you peace of mind that you and your investment are protected. Insurance must be in place before things go wrong for you to benefit from coverage. Get to the airport early. The old standby of being at the airport one hour before takeoff for domestic flights and two hours before international flights no longer apply. CAA recommends arriving at the airport at least two hours before domestic flight departures and at least three for international flights. Stay connected. It is important to have access to trusted, up-to-date information while travelling so you can monitor changing conditions and requirements and adapt accordingly. Bookmark the Global Affairs Canada website prior to departure and check it regularly while abroad. It is also a good idea to sign up for Registration of Canadians Abroad and stay in touch with a family or friend who has knowledge of your travel plans. Find these and more information at caasco.com/travelwise Note emergency contact numbers. Provide your travel agent with contact details while travelling abroad and keep all important phone numbers handy; this includes how to call for help and your travel insurance assistance phone number. It is also a good idea to keep a physical copy of all their reservation information and leave those details with a friend or family. Protect your ID. Ensure you have a digital and paper version of your Travel insurance wallet card, tickets to various events and attractions, and even your passport. You may also want to leave a copy of important paperwork with family members or friends. Pack your carry-on wisely. Place the most important items like passport/ID, boarding pass, travel itinerary, wallet, phone, charger, medications, toiletries, glasses/contacts, noise-canceling headphones, book/e-reader, snacks, empty water bottle, travel pillow, change of clothes, sweater, socks, pen, and reusable bags in your carry-on bag. For more information on travel insurance and how to stay protected, visit caasco.com/travelwise Based on the sample size of n=2,005 and with a confidence level of 95%, the margin of error for this research is +/- 2%.)
What's the True Story on the State of Tourism in Florida?
Tourism is one of the key economic drivers in Florida. The sector is responsible for approximately 10 percent of the Gross State Product (GSP), employs millions, and contributes billions to the state's economy. But how are things in the sector? It depends on the day, what you're reading or what you're watching: the industry in Florida is either booming or in a vulnerable situation. Here are two examples: Rising tariffs, visa delays, and shifting global travel trends have created a perfect storm, leading to a sharp drop in tourist numbers across Florida and several other U.S. states. The U.S. tourism industry is facing unprecedented challenges as international visitors choose alternative destinations amid political and economic shifts. According to recent data from the U.S. Travel Association, international visits to the U.S. saw a 14% decline in March, reflecting a broader global trend. However, the most significant impact has been felt among Canadian travelers, with a staggering 20.2% decrease in the number of Canadians visiting the U.S. This marks a troubling shift for the U.S., which has long relied on its neighboring country as a key source of international tourism. Florida, which has seen a decrease in tourism since the pandemic, is now facing a compounded crisis. The state, which historically attracted millions of international visitors, is seeing fewer long-term snowbirds, as well as a general decline in international arrivals. The state’s tourism sector, once a booming economic engine, is facing significant challenges. With both fewer foreign visitors and changes in local tourism trends, the state’s economy is under increasing strain. According to the World Travel & Journalism Council, the U.S. is on track to lose more than \$12 billion in international travel spending this year alone due to the decline in visitor numbers. June 06 - Travel and Tour World Whereas government officials are painting a very different picture. Florida welcomed 143 million visitors in 2024, setting a new tourism record for the state. State officials said this is the most visitors in a single year in Florida's history. The trend isn't slowing down, as more than 41 million people visited Florida in just the first three months of this year. May 21 - ABC News So there are questions that need to be answered: What is the current state of tourism in Florida? Have tariffs impacted visits from abroad? Does the high US dollar have anything to do with fewer people coming to the Sunshine State from outside of America? Has domestic travel increased with more Americans choosing Florida as a destination? If the sector is suffering from a decline in visitors, how can it adapt to be more attractive to tourists? If you are a reporter following the tourism industry - we're here to help. Peter Ricci is the Director of the Hospitality and Tourism Management program in Florida Atlantic University’s College of Business. He is a hospitality industry veteran with more than 20 years of managerial experience in segments including food service, lodging, incentive travel and destination marketing. Peter is available to speak with the media about tourism in Florida and the potential for gambling. Simply click on his icon to arrange an interview.
Trump's deployment of National Guard troops in L.A. sparks legal questions
Professor of Law James Sample discussed the new travel ban enacted by the Trump Administration and its legality, and the use of National Guard troops in Los Angeles with MSNBC.
Reclaiming 'Spend': A Retirement Rebellion
June is Pride Month—a celebration of identity, resilience, and the powerful act of reclaiming. Over the years, LGBTQ+ communities have reclaimed words that once marginalized them. “Queer” used to be a slur. Now, it’s a proud badge of honor. Similarly, the Black community has transformed language once used to oppress into expressions of cultural pride and connection. So, here's a thought: What if retirees approached the word “spend” similarly? Yes, you read that right. The psychological Tug-of-War This isn't just about numbers; it’s about narratives. Most retirees have spent their entire adult lives in accumulation mode: save, earn, invest, delay gratification, rinse, and repeat. But retirement flips that formula on its head, and most people weren’t provided with a “mental user guide” for the transition. Now, instead of saving, they’re expected to spend? Without a paycheck? It triggers everything from guilt to fear to a low-grade existential crisis. The Challenge of Saving for an Extended Period Let’s get serious for a moment. The data tells a troubling story: - Canadians over 65 collectively hold $1.5 trillion in home equity (CMHC, 2023) - The average retiree spends just $33,000 per year, despite often having far more resources (StatsCan, 2022) - Nearly 70% of retirees express anxiety about running out of money—despite having significant savings (FCAC, 2022) We’re talking about seniors who could afford dinner out, a trip to Tuscany, or finally buying that electric bike—and instead, they’re clipping coupons and debating the cost of almond milk. Why? Because spending still feels wrong. I Know a Thing or Two About Reclaiming Words As a proud member of the LGBTQ2+ community and a woman who has worked in the traditionally male-dominated world of finance, I’ve had a front-row seat to the power of language, both its ability to uplift and its tendency to wound. There were many boardrooms where I was not only the only woman but also the only gay person, and often the oldest person in the room. I didn’t just have a seat at the table; I had to earn, protect, and sometimes fight to keep it. I’ve learned that words can be weapons, but they can also be amour—if you know how to use them. Reflect on Your Boundaries Take a moment. Have you ever felt prejudged, marginalized, or dismissed? Perhaps it was due to your gender, sexuality, accent, skin colour, culture, or age. It leaves a mark. One way to preserve your dignity is by building a mental toolkit in advance. Prepare a few lines, questions, or quiet comebacks you can use when someone crosses the line—whether they intend to or not. Here are five strategies that helped me stand tall—even at five feet nothing: 1. Humour – A clever remark can defuse tension or highlight bias without confrontation. 2. Wit – A precisely timed comeback can silence a room more effectively than an argument. 3. Over-preparation – Know your stuff inside and out. Knowledge is power. 4. Grace under fire – Not everything deserves your energy. Rise above it when it matters. 5. Vulnerability – A simple “Ouch” or “Did you mean to hurt me?” can be quietly disarming—and deeply human. Let’s Talk About Microaggressions The term microaggression may sound small, but its effects are significant. These are the subtle, often unintentional slights: backhanded compliments, dismissive glances, and “jokes” that aren’t funny. They quietly chip away at your sense of belonging. Dr. Robin DiAngelo’s book White Fragility is a brilliant read on this topic. She explains how early socialization creates bias— “Good guys wear white hats. Bad guys wear black hats.” These unconscious associations become ingrained from an early age. Some people still say, “I’m not racist—I have a Black friend,” or “I’m not homophobic—my cousin is gay.” The truth? Knowing someone from a marginalized group doesn’t exempt you from unconscious bias. It might explain the behaviour, but it doesn’t excuse it. And no, there is no such thing as reverse discrimination. Discrimination operates within systems of power and history. When someone points out a biased comment or unconscious microaggression, they’re not discriminating against you—they’re holding up a mirror. That sting you feel? It’s not oppression. It’s shame—and it’s warranted. It signals that your intentions clashed with your impact. And that’s not a failure; it’s an invitation to grow. Calling it “reverse discrimination” is just a way to dodge discomfort. But real progress comes when we sit with that discomfort and ask: Why did this land the way it did? What am I missing? Because the truth is, being uncomfortable doesn’t mean you’re being attacked. It often means you’re being invited into a deeper understanding—and that’s something worth showing up for. Let’s Reclaim 'Spend' What if we flipped the script? What if spending in retirement was viewed as a badge of honour? Spending on your grandkids’ education, your bucket list adventures or even a high-end patio chair should not come with any shame. You’ve earned this. You’ve planned for this. It’s time to reclaim it. Let’s make “spend” the new “thrive.” Let’s make super-saver syndrome a thing of the past. Let the Parade Begin Imagine it: a Seniors’ Spend Parade. Golden confetti. Wheelchairs with spoilers. Luxury walkers with cupholders and chrome rims. T-shirts that say: - “Proud Spender. Zero Shame.” - “I’m not broke—I’m retired and woke.” - “My equity funds my gelato tour.” Dreams Aren’t Just for the Young What’s the point of spending decades building wealth if you never enjoy it? Reclaiming “spend” isn’t about being reckless—it’s about being intentional. So go ahead—book the trip. Upgrade the sofa. Take the wine tour. You’re not being irresponsible; you’re living the life you’ve earned. And if anyone questions it? Smile and say: “I’m reclaiming the word spend. Care to join the parade?” Sue Don’t Retire…Rewire! 8 Guilt-Free Ways to Spend in Retirement A checklist to help you spend proudly, wisely, and joyfully: ☐ Book the Trip – Travel isn’t a luxury; it’s a memory maker. ☐ Upgrade for Comfort – That recliner? That mattress? Worth every penny. ☐ Gift a Down Payment – Help your kids become homeowners. ☐ Fund a Grandchild’s Dream – Tuition, ballet, a first car—you’re building a legacy. ☐ Outsource the Chores – Pay for help so you can reclaim your time. ☐ Invest in Wellness – Healthy food, massage therapy, yoga. Health is wealth. ☐ Pursue a Passion – From pottery to piloting drones, go for it. ☐ Celebrate Milestones – Anniversaries, birthdays… or Tuesdays. Celebrate always! Want More? If this speaks to you, visit www.retirewithequity.ca and explore more: - From Saver to Spender: Navigating the Retirement Mindset - Money vs. Memories in Retirement - Fear Of Running Out (FORO) Each piece explores the emotional and psychological aspects of retirement—the parts no one talks about at your pension seminar.
James Sample Shares Legal Analysis on President Trump’s Travel Ban
Hofstra Law Professor James Sample shared his legal analysis on President Donald Trump’s new travel ban proclamation in an interview with ABC News. The proclamation bans 12 countries, citing national security concerns as the reason. In the news segment, Professor Sample said he expects the ban to be challenged in court. He also provided similar commentary for KYW Newsradio.
ChristianaCare Becomes First in Delaware to Offer CAR-T Therapy for Advanced Multiple Myeloma
ChristianaCare’s Helen F. Graham Cancer Center & Research Institute is the first in Delaware to offer a powerful new tool in the fight against multiple myeloma—a type of blood cancer that affects plasma cells in the bone marrow. That tool is a new chimeric antigen receptor (CAR) T-cell therapy, called CARVYKTI, which can improve treatment for adults with multiple myeloma that has returned or stopped responding to other treatments. “CAR-T cell therapy represents a paradigm shift in the treatment of multiple myeloma,” said Thomas Schwaab, M.D., Ph.D., Bank of America Endowed Medical Director of the Helen F. Graham Cancer Center & Research Institute." We are expanding access to this life-extending therapy right here in Delaware — close to home, close to hope. This is part of our ongoing commitment at the Graham Cancer Center to ensure our community has access to the most advanced cancer therapies.” Multiple myeloma is a relatively rare cancer, but it still affects a significant number of people each year. In the United States, it is estimated that around 36,110 new cases will be diagnosed in 2025, according to the American Cancer Society What is CAR-T Therapy? CAR-T cell therapy uses a patient’s own immune cells to fight cancer. Doctors first collect the patient’s T cells, which are a type of white blood cell that helps the body fight infections. In the lab, these T cells are reprogrammed by adding a special receptor called a chimeric antigen receptor (CAR). This receptor allows the T cells to recognize specific proteins on cancer cells, acting like a navigation system to help the T cells find and attack the cancer. After this genetic modification, the reprogrammed T cells are expanded in the lab to create a larger army of cancer-fighting cells. Then, they are infused back into the patient’s body, where they go on to find and destroy the cancer cells. This therapy is approved for adults who have already tried several standard treatments, like proteasome inhibitors, immunomodulators and anti-CD38 antibodies, without success. When those treatments stop working, CARVYKTI can offer a powerful new option. CAR T-cell therapy has given new hope to patients with multiple myeloma whose cancer has returned or stopped responding to other treatments. Many people see their cancer shrink or even disappear for a period of time, which can help them live longer and feel better. While the treatment can have short-term side effects, many patients report feeling stronger and having fewer symptoms once they recover. It’s not a cure, but for some, it can mean more time with loved ones and a better quality of life. “This therapy gives our patients a chance when other treatments have failed,” said Zhifu Xiang, M.D., medical oncologist at ChristianaCare Oncology Hematology. “It’s a deeply personalized approach that uses the patient’s own immune system to fight the cancer in a powerful new way. Being able to offer this locally means our patients don’t have to travel far for world-class care.” A Leader in Cell Therapy The Graham Cancer Center’s dedicated team of specialists have been offering CAR-T cell therapy for other cancer types, such as lymphoma and leukemia, since 2018. The center is also recognized by the Foundation for the Accreditation of Cellular Therapy (FACT) for meeting the highest standards in safety, quality and patient care. To learn more about CAR-T cell therapy or other cancer treatments at ChristianaCare, visit christianacare.org/cancer or call the Helen F. Graham Cancer Center & Research Institute at 302-733-HOPE (4673).
