Experts Matter. Find Yours.

Connect for media, speaking, professional opportunities & more.

National Science Foundation awards $2.5M Lifelong Learning Grant to support Georgia Southern computer science and IT departments, 161 scholarships featured image

National Science Foundation awards $2.5M Lifelong Learning Grant to support Georgia Southern computer science and IT departments, 161 scholarships

The National Science Foundation announced a $2.5 million award supporting Georgia Southern University researchers in addressing high-demand workforce needs in information technology and computer science fields. The funded project, “Enabling Lifelong Success in an Information Technology Workforce,” adapts and evaluates evidence-based student support activities within the IT Department, one of the units in the Allen E. Paulson College of Engineering and Computing. The goal of the project is to identify a group of highly qualified students and to render 161 scholarships over a six-year period in an effort to increase student retention and graduation rates. “This is great news for the IT program at Georgia Southern, and it will provide a positive impact to the surrounding area as businesses’ needs for IT professionals increase,” said interim Vice President of Research and Economic Development Chris Curtis, Ph.D. Georgia Southern Professor and Department of Information Technology Chair Yiming Ji, Ph.D., is taking the lead on the grant, which, he noted, has the potential to have a profound impact on students. “This project will train a pool of talented students, especially those with financial needs, and prepare them for successful careers in IT,” said Ji. “With scholarships from the grant, students will have time to focus on studying, instead of having to work to make ends meet. These students will also receive dedicated support, including academic advising, research opportunities, internship and career service and much more. The result is that these students will become confident and have a greater future in IT careers.” The project involves four researchers, including Lei Chen, Ph.D., (co-PI), professor of IT; Hayden Wimmer, Ph.D., (co-PI), associate professor of IT; Elise Cain, Ph.D., (co-PI), assistant professor of leadership’ and Kania Greer, Ed.D., (external evaluator), program coordinator of the Center for STEM education. The project also received support from the Allen E. Paulson College of Engineering and Computing (CEC) and the Georgia Southern Office of Research. The national and regional demand for computer and IT professionals remains high. “This project will directly benefit our local, regional and national economies,” said CEC Dean Craig Harvey, Ph.D. “High-tech industries are already in and being attracted to the Savannah area, and the locations of Georgia Southern University’s campuses provide unique opportunities to train high-quality computing and IT professionals who are in high demand.” The Department of Information Technology offers a wide range of undergraduate and graduate computer and IT programs at Georgia Southern, in addition to a new Ph.D. program in applied computing. This grant is the first of its kind to be received by the IT department. The department hopes that through the use of this grant, they will build stronger partnerships with businesses and federal or state government organizations, among others. Interested in knowing more? To arrange an interview with Yiming Ji or Chris Curtis, simply connect with Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.

2 min. read
Bioenergy experts welcome commitment to sustainability in UK’s new Biomass Strategy featured image

Bioenergy experts welcome commitment to sustainability in UK’s new Biomass Strategy

New strategy outlines role of biomass in UK’s transition to net zero, with sustainability as major theme Supergen Bioenergy Hub experts worked with government departments to provide scientific evidence and insight They welcome the holistic view of sustainability in the Biomass Strategy and call for action to deliver its ambitions. A group of bioenergy experts have welcomed the Government’s new UK Biomass Strategy, but say urgent action is now vital to shape its ambitions into deliverable policies. Researchers at the Supergen Bioenergy Hub - led by Aston University - worked closely with government departments to provide scientific evidence to inform the strategy, which outlines the role biomass will play in supporting the UK’s transition to net zero and how this will be achieved. Professor Patricia Thornley, who leads the Hub, says: “This is a comprehensive and considered biomass strategy that, rightly, places sustainability at the heart of UK bioenergy development. The challenge is now to produce actions that can deliver the sustainable system of biomass required to achieve net zero.” Sustainability is a major theme within the new strategy. It includes a review of how existing sustainability policies could be improved, as well as a commitment to developing a cross-sectoral sustainability framework (subject to consultation) to ensure sustainability across the many different applications of biomass. This follows previous work led by Dr Mirjam Rӧder, Systems Topic Group Lead in the Supergen Bioenergy Hub, calling for harmonised sustainability standards across different biomass applications, which is referenced in the strategy. Dr Rӧder says: “We need rigorous approaches to sustainability governance that go beyond emissions. Considering wider environmental, social and economic trade-offs is essential for true sustainability and building trust in bioenergy projects.” The strategy considers the amount of biomass resource that might be available to the UK in the future, highlighting the importance of both imported and domestically produced biomass resources. Professor Thornley comments: “It is important that the strategy recognises the potential of imported as well as indigenous biomass in achieving global greenhouse gas reductions. Sustainable systems should grow, convert and use biomass in the locations where they can deliver most impact, ensuring we take account of all supply chain emissions. We shouldn’t shy away from imports where the source is sustainable and the overall system makes environmental, economic and social sense.” The strategy also considers how biomass should be prioritised across a variety of applications to best support the transition to net zero. Biomass applications ranging from transport fuels and hydrogen to domestic and industrial heating are recognised as important, but in the medium to long term the focus is on integration of bioenergy with carbon capture and storage (BECCS). BECCS is an emerging technology where the CO2 that may be released during the production and use of electricity, fuels or products derived from biomass is captured and stored, potentially resulting in negative emissions. Professor Thornley comments: “The priority use framework outlined in the Biomass Strategy makes eminent sense. The UK (and the global energy system) needs carbon dioxide removals to deliver net zero. BECCS has an absolutely key role to play, as reflected in the strategy. Again, while this is encouraging to see, we must not underestimate the challenges of moving towards such a radically different system at scale.” “Relying on future BECCS deployment alone to counterbalance the current excess of greenhouse gas emissions would not enable the full potential and benefits of BECCS. BECCS should be deployed alongside measures to transition away from the use of fossil fuels, not instead of them,” adds Dr Joanna Sparks, Biomass Policy Fellow at the Supergen Bioenergy Hub, who engaged closely with government departments as they developed the strategy. Dr Sparks led an extensive policy engagement and knowledge transfer process to ensure that those developing the strategy had full access to the breadth and depth of UK scientific and engineering academic expertise, ensuring a robust, independent scientific base. Professor Thornley believes continued engagement between policymakers, academics and the wider sector is vital in achieving the next steps in the delivery of the Government’s strategy. She says: “The key to successful long-term results is a close partnership between academia, industry and policy stakeholders so that we can anticipate problems and plan the pathways to success.”

Patricia Thornley profile photoDr Mirjam Röder profile photo
3 min. read
Optical research illuminates a possible future for computing technology featured image

Optical research illuminates a possible future for computing technology

Nathaniel Kinsey, Ph.D., Engineering Foundation Professor in the Department of Electrical and Computer Engineering (ECE), is leading a group to bring new relevance to a decades-old computing concept called a perceptron. Emulating biological neuron functions of the messenger cells within the body’s central nervous system, perceptrons are an algorithmic model for classifying binary input. When combined within a neural network, perceptrons become a powerful component for machine learning. However, instead of using traditional digital processing, Kinsey seeks to create this system using light with funding from the Air Force Office of Scientific Research. This “nonlinear optical perceptron” is an ambitious undertaking that blends advanced optics, machine learning and nanotechnology. “If you put a black sheet outside on a sunny day, it heats up, causing properties such as its refractive index to change,” Kinsey said. “That’s because the object is absorbing various wavelengths of light. Now, if you design a material that is orders of magnitude more complex than a sheet of black plastic, we can use this change in refractive index to modify the reflection or transmission of individual colors – controlling the flow of light with light.” Refractive index is an expression of a material’s ability to bend light. Researchers can harness those refractive qualities to create a switch similar to the binary 1-0 base of digital silicon chip computing. Kinsey and collaborators from the U.S. National Institute of Standards and Technology, including his former VCU Ph.D. student Dhruv Fomra, are currently working to design a new kind of optically sensitive material. Their goal is to engineer and produce a device combining a unique nonlinear material, called epsilon-near-zero, and a nanostructured surface to offer improved control over transmission and reflection of light. Kinsey’s prior research has demonstrated that epsilon-near-zero materials combine unique features that allow their refractive index to be modified quite radically – from 0.3 to 1.3 under optical illumination – which is roughly equivalent to the difference between a reflective metal and transparent water. While an effective binary switch, the large change in index requires a lot of energy (~1 milli-Joules per square centimeter). By combining epsilon-near-zero with a specifically designed nanostructure exhibiting surface lattice resonance, Kinsey hopes to achieve a reduction in the required energy to activate the response. The unique response of a nanostructure exhibiting surface lattice resonance allows light to effectively be bent 90 degrees, arriving perpendicular to the surface while being split into two waves that travel along the surface. When a large area of the nanostructure is illuminated, the waves traveling along the surface mix, where they interfere constructively or destructively with each other. This interference can produce strong modification to reflection and transmission that is very sensitive to the geometry of the nanostructure, the wavelength of the incident light and the refractive index of the surrounding materials. The mixing of optical signals along the surface can also selectively switch regions of the epsilon-near-zero material thereby performing processing operations. A key aspect of Kinsey’s work is to build nonlinear components, like diodes and transistors, that use optical signals instead of electrical ones. Transistors and other traditional electronic components are nonlinear by default because electrical charges strongly interact with each other (for example, two electrons will tend to repel each other). Creating optical nonlinear components is challenging because photons do not strongly interact, they just pass through each other. To correct for this, Kinsey employs materials whose properties change in response to incident light, but the interaction is weak and thus requires large energies to utilize. Kinsey’s device aims to reduce that energy requirement while simultaneously shaping light to perform useful operations through the use of the nanostructured surface and lightwave interference. The United States Department of Defense sees optical computing as the next step in military imaging. Kinsey’s work, while challenging, has potential to yield an enormous payoff. “Let’s say you want to find a tank within an image,” Kinsey said, “Using a camera to capture the scene, translate that image into an electrical signal and run it through a traditional, silicon-circuit-based computer processor takes a lot of processing power. Especially when you try to detect, transfer, and process higher pixel resolutions. With the nonlinear optical perceptron, we’re trying to discover if we can perform the same kinds of operations purely in the optical domain without having to translate anything into electrical signals.” Linear optical systems, like metasurfaces and photonic integrated circuits, can already process information using only a fraction of the power of traditional tools. Building nonlinear optical systems would expand the functionality of these existing linear systems, making them ideal for remote sensing platforms on drones and satellites. Initially, the resolution would not be as sharp as traditional cameras, but optical processing built into the device would translate an image into a notification of tanks, troops on the move, for example. Kinsey suggests optical-computing surveillance would make an ideal early warning system to supplement traditional technology. “Elimination or minimization of electronics has been a kind of engineering holy grail for a number of years,” Kinsey said, “For situations where information naturally exists in the form of light, why not have an optical-in and optical-out system without electronics in the middle?” Linear optical computing uses minimal power, but is not capable of complex image processing. Kinsey’s research seeks to answer if the additional power requirement of nonlinear optical computing is worthwhile given its ability to handle more complex processing tasks. Nonlinear optical computing could be applied to a number of non-military applications. In driverless cars, optical computing could make better light detection and ranging equipment (better known as LIDAR). Dark field microscopy already uses related optical processing techniques for ‘edge detection’ that allows researchers to directly view details without the electronic processing of an image. Telecommunications could also benefit from optical processing, using optical neural networks to read address labels and send data packets without having to do an optical to electrical conversion. The concept of optical computing is not new, but interest (and funding) in theory and development waned in the 1980s and 1990s when silicon chip processing proved to be more cost effective. Recent years have seen many advancements in computing, but the more recent slowdown in scaling of silicon-based technologies have opened the door to new data processing technologies. “Optical computing could be the next big thing in computing technology,” Kinsey said. “But there are plenty of other contenders — such as quantum computing — for the next new presence in the computational ecosystem. Whatever comes up, I think that photonics and optics are going to be more and more prevalent in these new ways of computation, even if it doesn’t look like a processor that does optical computing.” Kinsey and other researchers working in the field are in the early stages of scientific exploration into these optical computing devices. Consumer applications are still decades away, but with silicon-based systems reaching the limit of their potential, the future for this light-based technology is bright.

5 min. read
Inspired by Palm Trees' Resilience, Florida Tech Researcher Seeks to Strengthen Made Materials   featured image

Inspired by Palm Trees' Resilience, Florida Tech Researcher Seeks to Strengthen Made Materials

Inspired by the tiny, circular vessels in the trunks of palm trees that allow the iconic plants to bend but not snap in strong winds, an assistant professor of aerospace engineering is researching how to recreate Mother Nature’s handiwork in additive manufacturing. Mirmilad Mirsayar received a three-year, $200,627 research grant from the National Science Foundation’s highly competitive Mechanics of Materials and Structures program under the Division of Civil, Mechanical and Manufacturing Innovation to study the mechanics and physics of crack propagation in functionally graded cellular structures made by additive manufacturing. That’s the process of creating an object by building it one layer at a time. Mirsayar is the sole principal investigator of the project, “Understanding Mixed-Mode Fracture Mechanics in Additively Manufacturable Functionally Graded Microcellular Solids.” His research is inspired by cellular patterns seen in palm trees and butterfly wings. For example, unlike oak trees and some others, the palm tree’s center contains those vessels, distributed non-uniformly throughout the trunk, that help it survive in Florida’s windy environment. Other biological systems, such as bone, honeycombs and marine sponges, also serve as inspirations from nature. “I’m enjoying this research because I’m learning from nature and I’m applying fundamentals of physics and mathematics to solve a very important engineering problem while training the next generation of engineers and researchers,” Mirsayar said. Materials with cellular structures, such as aircraft wings and artificial bones, are widely used in industries such as aerospace and biomedical. As additive manufacturing has advanced, materials with cellular structures and increasingly complex geometrical patterns can be precisely manufactured. Mirsayar is looking at ways to optimize these strong and light cellular structures made by additive manufacturing to achieve the highest resistance against failure under complex operational loading conditions, such as bending tension, compression and torsion. What could this mean for additive manufacturing? How could stronger materials change what or how we build? Contact Florida Tech Media Communications Director Adam Lowenstein at adam@fit.edu to schedule an interview with Dr. Mirsayar.

2 min. read
#Expert Research: Biodegradable ultrasound implant could improve brain tumour treatments featured image

#Expert Research: Biodegradable ultrasound implant could improve brain tumour treatments

One of the challenges in treating certain types of brain cancer is the way that the blood-brain barrier prevents chemotherapy drugs from reaching the tumors they're meant to target. UConn's Thanh Nguyen, a biomedical and mechanical engineer, is developing new technology that could improve how we are able to treat brain tumors.  He recently spoke with Physics World about this groundbreaking research: A new type of biodegradable ultrasound implant based on piezoelectric nanofibres could improve outcomes for patients with brain cancer. Researchers led by Thanh Nguyen from the the University of Connecticut’s department of mechanical engineering fabricated the devices from crystals of glycine, an amino acid found in the human body. Glycine is not only non-toxic and biodegradable, it is also highly piezoelectric, enabling the creation of a powerful ultrasound transducer that could help treat brain tumours. Brain tumours are particularly difficult to treat because the chemotherapy drugs that would be effective in tackling them are blocked from entering the brain by the blood–brain barrier (BBB). This barrier is a very tight junction of cells lining the blood vessel walls that prevents particles and large molecules from making their way through and damaging the brain. However, ultrasound can be safely used to temporarily alter the shape of the barrier cells such that chemotherapy drugs circulating in the bloodstream can pass through to the brain tissues. Currently, to achieve such BBB opening requires the use of multiple ultrasound transducers located outside the body, together with very high intensity ultrasound to enable penetration through the thick human skull bone. “That strong ultrasound can easily damage brain tissues and is not practical for multiple-time applications which are required to repeatedly deliver chemotherapeutics,” Nguyen tells Physics World. By contrast, the team’s new device would be implanted during the tumour removal surgery, and “can generate a powerful acoustic wave deep inside the brain tissues under a small supplied voltage to open the BBB”. The ultrasound would be triggered repeatedly as required to deliver the chemotherapy that kills off the residual cancer cells at tumour sites. After a set period of time following treatment the implant biodegrades, thereby eliminating the need for surgery to remove it. The research, reported in Science Advances, demonstrated that the team’s device used in conjunction with the chemotherapy drug paclitaxel significantly extended the lifetime of mice with glioblastomas (the most aggressive form of brain tumour) compared with mice receiving the drugs but no ultrasound treatment. This is fascinating research and if you are interesting in covering this topic, then let us help. Professor Nguyen focuses on biointegrated materials and devices at nano- and micro-scales for applications in biomedicine, and he's available to speak to media about his research. Simply click on his icon now to arrange an interview today.

Thanh Nguyen, Ph.D. profile photo
2 min. read
Florida Tech Shark Biologist
Stars in National Geographic Program on Shark Attacks featured image

Florida Tech Shark Biologist Stars in National Geographic Program on Shark Attacks

Toby Daly-Engel, the distinguished shark biologist and director of Florida Tech’s Shark Conservation Lab, is a featured expert on “When Sharks Attack…and Why,” an eight-episode program debuting this week as part of National Geographic’s SharkFest 2023. The series debuts July 6 at 9 p.m. Eastern on National Geographic with new episodes airing nightly through July 12. It is also now streaming on Disney+, Hulu and the National Geographic website. The series will air on Nat Geo Wild starting July 26 at 8 p.m. Eastern. As its name suggests, “When Sharks Attack…and Why” investigates shark encounters in America and around the world. “Many attacks are appearing in new and surprising places,” the network notes. Episodes explore incidents in New York, California, Hawaii, Indonesia, Australia and elsewhere. At Florida Tech, Daly-Engel conducts research using a combination of genomics, field ecology and modeling to study shark mating systems and habitat use, and the impacts of climate change on shark populations. On the program, she is our expert guide to anatomical and physiological aspects of sharks, many of which are unique to this species. We first meet Daly-Engel in Episode 1, New York Nightmare. Filmed in her lab, she talks viewers through key parts of a shark’s body using a small dogfish shark. She tells viewers that while a shark’s sense of smell is often touted, these apex predators also have powerful hearing, far better than humans. (In a later episode, she notes a shark’s vision in murky waters is about 10 times stronger than human vision in those conditions.) “I really enjoyed delving into the science behind shark-human interactions,” Daly-Engel said, “and busting the myths that make people afraid of the water.” Daly-Engel is no stranger to SharkFest. Last year she was featured in another SharkFest series, “Shark Attack File,” and she has been on SharkFest and Discovery’s Shark Week programing multiple times, including 2021 when she appeared on three programs across both networks. Looking to know more about shark encounters and attacks? Then let us help with your coverage and questions. Toby Daly-Engel is an assistant professor in the Department of Ocean Engineering and Marine Sciences department at Florida Tech. He's available to speak with media about this topic - simply click on his icon now to arrange an interview today.

Toby S. Daly-Engel, Ph.D. profile photo
2 min. read
Solving sargassum: Florida Tech researchers exploring ways to make seaweed useful  featured image

Solving sargassum: Florida Tech researchers exploring ways to make seaweed useful

Sargassum, a type of large brown seaweed, has been in the news lately, with a massive blob that’s visible from space and threatening ocean life. University research funded by the U.S. Environmental Protection Agency could address the issue, while also helping solve another problem in our water. Toufiq Reza, an assistant professor of chemical engineering in the Department of Biomedical and Chemical Engineering and Sciences, along with research students Cadianne Chambers, Swarna Saha, Savannah Grimes and Josh Calhoun, were part of the research paper, “Physical and morphological alteration of Sargassum‐derived ultraporous superactivated hydrochar with remarkable cationic dye adsorption.” The paper was published in the May edition of Springer Nature’s Biomass Conversion and Biorefinery journal. The paper is part of a three-year, nearly $400,000 EPA grant to examine different uses of sargassum. It explains that the team can produce biochar from sargassum that can filter water. Though the team has tested model dye in this paper, they plan to extend their research for other applications including harmful algal bloom remediation and nutrient recovery in the future. While sargassum has been around for centuries (Christopher Columbus is credited with the first written account after he encountered it in 1492), and you’ve probably seen bits of brownish seaweed on the beach – it sometimes smells like rotten eggs – the quantities in the ocean and washing up on shores are a more recent phenomenon. There are multiple reasons behind the increased amount of sargassum, including global warming that intensifies sargassum production and nutrient runoff making its way to ocean water and overfertilizing the seaweed growth. More sargassum is expected to show up on Florida shores in the future, inspiring the team to explore more positive uses of the abundant seaweed. “In the next couple of years, we’ll be seeing much more sargassum coming into our way. It’s not a common practice to utilize sargassum,” Reza said. “We go to a beach and then we see a little bit of sargassum just dried out. That doesn’t bother us that much, but when it started to come as a foot-tall sargassum wave, that’s where it gets more alarming.” Sargassum in the lab is labor intensive. Because it contains salt from the ocean, it is washed with tap water first, then put in a freezer for preservation. Next, it goes through hydrothermal carbonization, a thermochemical process that uses heat and pressure to convert biomass and organic waste (such as the sargassum being used) into solid hydrochar. Lastly, the solid char goes through pyrolysis, where it is heated in a high-temperature, oxygen-free chamber into a biochar that is used to filter water. For Swarna Saha, a first-year doctoral student, her goal as a researcher is to identify an environmental problem and come up with a sustainable solution. Having grown up in Bangladesh around textile factories that generate dyes that pollute the surface water, she was inspired to work on solutions that improved water quality with biochar. “I came in the project when we were experimenting on dye adsorption and saw how a tiny amount of biochar changes the color of the water,” she said. “For me, seeing the results made me the happiest. When we saw that our biochar is effective, that is the biggest achievement for me. That made me happy.” Cadianne Chambers, a second-year doctoral researcher, was motivated by her home country of Jamaica and its massive issues with sargassum. Chambers has heard accounts of fishermen unable to go out to sea because of the sargassum buildup. A popular destination for summer vacation, Jamaica is facing serious environmental and economic problems with waves of sargassum. “A team in Jamaica saw that article and they reached out to us, and they’re trying to cultivate sargassum. They want us to teach them how to make export-quality hydrochar and biochar, which could help solve their environmental problem and generate revenues,” Chambers said. “So, everything is just connecting nicely and I’m hoping to continue our collaboration with them. If it’s something that I can go home and put my PhD research to work and help the community, that would be really satisfying.” Looking to know more about sargassum and the ground-breaking research taking place at Florida Tech? Then let us help with your coverage and questions.  Toufiq Reza is an assistant professor in the biomedical and chemical engineering and sciences department at Florida Tech. He's available to speak with media about this topic - simply click on his icon now to arrange an interview today.

Toufiq Reza, Ph.D. profile photo
3 min. read
Expert opinion: Tories promise spending for the creative industries but need to invest in education first  featured image

Expert opinion: Tories promise spending for the creative industries but need to invest in education first

If you’re looking for comment on this week’s announcement about government’s proposed £50bn investment in creative industries we have a design expert available. Dr Tim Whitehead is associate dean and senior lecturer, engineering and technology, Aston University. He believes that although the Tory's promise spending for the creative industries they need to invest in education first. His full response is attached and below: “This week the government announced a plan to boost the creative industries by £50bn by 2030 and invest £77m in funding for the sector. “This news is fantastic and long overdue. The UK design economy contributes £97.4bn GVA and for every £1 invested in design we see a return of £4 to the wider economy. “The creative sector is a major British export with film, TV, music being some of the biggest exports. However, we also have physical products; If you’ve ever used an iPhone, a Dyson or ridden on a London double decker bus then you’ve used world class British design. “The funding is welcome, however we really need investment in our schools to teach creativity and align this with recent announcements in maths education. “The majority of our most successful designers / creative engineers started with Design and Technology at school. “Between academic years 2009-10 and 2021-22, the proportion of pupils taking Design and Technology GCSEs fell from around 42% to 27% in all schools in England. With only a minor increase in pupils taking Art and Design GCSE which increased from 27% to 29% over the same period. “There is a big gap here, and we really need to ensure that children have access to a creative education as school. “By embedding creativity into the next generation it will help foster new creative engineers data scientists etc. and the next Dyson.” Dr Tim Whitehead, associate dean and senior lecturer, engineering and technology, Aston University For inquiries contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk

2 min. read
Pioneering UConn Researcher Regrows Human Bone Using a Biodegradable Implant featured image

Pioneering UConn Researcher Regrows Human Bone Using a Biodegradable Implant

A pioneer in the field of regenerative engineering, UConn's Dr. Cato T. Laurencin is charging toward his goal of regenerating a human limb by the year 2030.  In a step toward reaching that goal, Dr. Laurencin and his team have detailed their success in regrowing bone using a plant-derived molecule in a recent study published by PNAS, marking a major step toward affordable, safe bone regeneration and growing replacement limbs. Dr. Laurencin discussed this impressive breakthrough this week with Hearst Connecticut Media: Most bone fractures heal reasonably well with care. But in severe breaks, where sections of bones are missing, or in crush injuries bones don’t always heal very well. In those cases, self-grafts or donated grafts of healthy bone from other, non-broken bones can be used to help close the gaps. But bone grafts don’t always take. Since about 2001, recombinant bone morphogenic proteins have been used to help stimulate bone growth in injuries where bone wouldn’t otherwise heal but their use has limits. While they work on long bone fractures, like those in your limbs, they’re not used on more complex bones. In some experimental treatments with fractured pelvises, recombinant bone protein caused bone tissue to form outside the skeleton. Forming bone tissue outside the skeleton is one of the more troubling side effects of this treatment. Bone tissue engineering seeks to get around this by developing implants that use adult stem cells to direct the growth of new bone across breaks that bones could not heal on their own. Some of this work involves building custom implants designed to mimic the missing bone to guide bone healing. Others attempt to deliver the bone protein in an implant, stopping it from leaving the injury area, to prevent side effects. These bone treatments are also expensive. In a meta-analysis from 2006, researchers found that they cost more than standard care for severe fractures. But UConn team took a different approach, using the drug forskolin, a molecule derived from a plant in the mint family. Forskolin triggers cells to make something called “cyclic AMP” a messenger molecule that is normally made in response to hormones. This messenger molecule turns on a wide variety of cell functions depending on what cells in which locations it stimulates. “We were intrigued by being able to find some natural material that people were already consuming in quantity,” said Dr. Laurencin, “But obviously there’s a difference between ingesting it and putting it on one location, like a bone site.” Dr. Laurencin’s team created a biodegradable plastic implant impregnated with forskolin, testing this on rabbits. The implants guided the creation of new bone tissue after 12 weeks. If you're a journalist looking to know more about this groundbreaking research taking place at UConn, let us help with your questions and coverage. Dr. Cato Laurencin, CEO of the Cato T. Laurencin Institute for Regenerative Engineering at UConn, is available to for interviews. Simply click on his icon now to arrange a time to talk today.

Cato Laurencin, M.D., Ph.D. profile photo
2 min. read
Aston University wins £1.8m to boost West Midlands low carbon markets featured image

Aston University wins £1.8m to boost West Midlands low carbon markets

• Aston University and local industry to develop technology to convert organic material into commercially valuable products • Sawdust, diseased trees and dried chicken litter among what can be transformed into sustainable bioproducts • West Midlands companies are invited to join a cluster to develop new low carbon products for growing markets. Aston University is to receive £1.8 million to transform the West Midlands into a powerhouse of low-carbon product development and commercialisation. The University will be building on its existing research facilities to lead the region’s Biochar CleanTech Accelerator as part of the West Midlands Innovation Accelerator. The project was set up with the aim to secure export contracts for low carbon products worth over £200 million, to be made by a regional industrial cluster. It is hoped that the development of a low-carbon business cluster in the West Midlands will open up new domestic and export markets to help rebuild the region’s engineering and manufacturing status. Biochar, a sustainable form of charcoal, can be used as a soil and plant growth enhancer. It stores carbon in the ground, so there are fewer greenhouse gases in the atmosphere. Other products such as oils can be used as low carbon fuels for boilers and engines and the liquid by-product can be used for low carbon weedkiller, fungicide and plant growth. Aston University’s innovative technology is installed at its urban biochar demonstrator in south Birmingham. The project is based on the strengths of the University’s Energy and Bioproducts Research Institute (EBRI) and its Centre for the Circular Economy and Advanced Sustainability (CEAS). Tim Miller, director of engagement at EBRI, said: “This new development has the potential to rebuild product development, engineering and manufacturing in our region. “The project aims to commercialise knowledge, facilities and the results of long-term university research for the benefit of the environment and our regional economy. “Using the University’s existing expertise and facilities we have the potential to launch new technology-based opportunities as they emerge and mature, The Biochar CleanTech Accelerator is part of the West Midlands Innovation Accelerator which was first announced in the government’s 2022 Levelling up White Paper and started this spring. It is funded through a share of a £100m from Innovate UK, to be divided by three regional innovation accelerators over the next two years. Launched by the West Midlands Combined Authority (WMCA) in March 2023, it will target investment on projects enabling new solutions around Medical and Clean Technologies, to further reinforce the region’s position at the frontier of the UK innovation revolution. The University will also play a key role in two other projects in the West Midlands Innovation Accelerator. Companies interested in joining the cluster can get further information at https://www.aston.ac.uk/biochar-cleantech-accelerator or emailing biochar@aston.ac.uk

Tim Miller profile photo
2 min. read