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The Loneliness Epidemic: Fathoming Feelings and Emotions
Last month, United States surgeon general Vivek Murthy released an advisory to address a budding "public health crisis." The culprit is not immediately visible, like the shutdown-spurring COVID-19 pandemic, but it is currently affecting nearly half of all adults in the U.S. It's our widespread senses of loneliness and isolation, and Murthy says addressing these feelings is "critical" to addressing issues of mental health in America. Assistant professor Guy Weissinger, PhD, MPhil, RN, is a nurse, scientist and educator focusing on mental health and health systems at Villanova University's M. Louise Fitzpatrick College of Nursing. Dr. Weissinger believes, despite the difficult nature of navigating unseen nemeses, there are ways to quell this epidemic and save lives. Q: Why is the feeling of loneliness now seen as a crisis? Dr. Weissinger: It's important to understand that loneliness is not just a person not having friends or not having good relationships. Loneliness is a feeling, the sense that one is distant from others while yearning to feel connected. These two sides make loneliness hard to understand sometimes because there are people who are happy with low amounts of social engagement and there are people who feel lonely even when they are surrounded by friends. Like hunger saying it's time to eat, loneliness is a message that we are not fulfilling a social and psychological need—and it's a big problem because so many parts of our mental and physical health are tied to having active social engagement. Q: In an increasingly connected world, why are these feelings of isolation also increasing? DW: Interacting with other people doesn't actually make us less lonely, especially through things like social media. A sense of being emotionally close to others—reciprocity of attention and care—is what makes people less lonely. It's clear that people are spending less time focused on social relationships than in the past. The "connection" that we have through social media is not the connection that addresses our deeper psychological needs. Upvotes and clicks feel good, but they do not make us feel understood and appreciated for our whole selves. In-depth conversations, shared projects and laughing about inside jokes—the kind of things that happen over extended interactions—are what actually make us feel less lonely. This isn't to say that people don't connect and get less lonely when they engage digitally. It's about the quality and depth of interactions, not the modality. Q: What are some ways loneliness and isolation can be addressed? DW: If you are lonely, reach out to someone. Often, we wait for others to initiate because we don't want to be a bother or fear rejection. If they say no, move on to another person. It's hard not to take it personally, but if you are feeling lonely, the worst thing to do is to dwell on why it's hard to schedule with "Friend A" and instead focus on finding another person to connect with. And when you are with people, try to focus your attention on them. Put away your phone or other distractions and ask open-ended questions like, "What's the best thing that happened this week?" or "How has [thing you know they enjoy] been recently?" Even if it's not a person that you are super close to, both listening to them and opening up yourself helps you feel more connected. If you are worried that someone else is lonely, ask them to do something, especially if it's something you know they like. Asking a person who loves movies to go see a movie with you will make them feel like you care more than asking them to a yarn festival, even if you'd prefer the yarn festival. Dr. Weissinger says people who report that they have a regular social connection with others, especially in person, are more physically active, less likely to be depressed and are better able to better navigate difficult circumstances. "While we often talk about resilience as being an individual trait, having good social support is one of the most powerful kinds of resilience," mentions Dr. Weissinger. "When times are hard, we can rely on our friends, family and larger social network to help with problem solving, resources, emotional support and even just simple distraction." Dr. Weissinger says that a crisis as large as loneliness and isolation can't be solved through the recommendations of one person, but says connection and unity are key to fighting back against this epidemic. "People with more and more varied connections don't have simpler lives or less bad things happen to them, but they get through them easier because they can rely on others to help them manage in the ways they need."
Program addresses disparities in breast cancer between Black and white women ChristianaCare’s Helen F. Graham Cancer Center & Research Institute is partnering with Susan G. Komen®, the world’s leading breast cancer organization, in an expansion of Komen’s screening and diagnostics program to income-eligible residents of Delaware. Under the program, Delaware women who meet income qualifications will be able to access no-cost breast cancer screening mammograms and necessary diagnostic follow-up tests. Once approved by Susan G. Komen for care, they can select ChristianaCare for services. ChristianaCare is one of 20 health systems nationwide partnering with Susan G. Komen in the program, which seeks to reduce disparities in areas where the breast cancer mortality gap between Black and white women is the greatest. “The Graham Cancer Center is proud of its longstanding partnership with Susan G. Komen to bring breast cancer screenings to our community and to reduce disparities and save lives,” said Nicholas Petrelli, M.D., Bank of America endowed medical director of the Helen F. Graham Cancer Center & Research Institute. “This new partnership with Komen is an innovative way that we are stronger together as we continue to reduce barriers to care and help more Delaware women access timely breast imaging and treatment,” he said. “The screening and diagnostics program is critical for individuals who may have been putting off their breast cancer screening due to concerns about cost,” said Nora Katurakes, RN, OCN, manager of the Graham Cancer Center’s Community Outreach & Education program. “Early detection saves lives, and cost should not be a barrier to accessing high-quality health care services for anyone in need. This program seeks to achieve health equity for all.” “Early detection saves lives, and cost should not be a barrier to accessing high-quality health care services for anyone in need,” said Nora Katurakes, RN, OCN, manager of Community Outreach and Education According to the Delaware Division of Public Health, breast cancer is the most common cancer diagnosed among women in Delaware, and Black women are disproportionately more affected by breast cancer than white and Hispanic women and have a higher mortality rate. In addition, Black women in Delaware have among the highest incidence rates in the U.S. of triple negative breast cancer, an aggressive form of the disease that is harder to treat and more likely to return. The Komen screening and diagnostics program is a service provided through the Komen Patient Care Center. Last year, Susan G. Komen provided nearly 3,000 screening and diagnostics services. Komen hopes to serve another 3,000 individuals in 2023. To be eligible for the program, individuals must have a current annual household income at or below 300% of the Federal Poverty Level. For one person that is $43,740. A two-person family must have a $59,160 household income to be eligible. The Tatiana Copeland Breast Center at the Helen F. Graham Cancer Center & Research Institute is one of the few facilities in the region devoted exclusively to breast care, diagnosis and treatment, and was the first center in the state to offer high-definition 3D mammography imaging. About Breast Cancer Screening Screening mammography tests are used to find breast cancer before it causes any warning signs or symptoms. Regular screening tests along with follow-up tests and treatment, if diagnosed, reduce an individual’s chance of dying from breast cancer. Mammography is a test that uses X-rays to create images of the breast. These images are called mammograms. A radiologist trained to read mammograms studies the images and looks for signs of breast cancer. A mammogram may show: No signs of breast cancer. A benign (not cancer) condition or other change that does not suggest cancer. An abnormal finding that needs follow-up tests to rule out cancer. Income eligible people seeking access to a breast cancer screening mammogram or diagnostic service should contact the Komen Breast Care Helpline at 1-877-465-6636 or helpline@komen.org to learn more. Individuals who would like more information about breast cancer screening in Delaware can also call ChristianaCare Community Health Outreach & Education at 302-623-4661.
Aston University celebrates becoming a University of Sanctuary with official event
Aston University officially celebrated becoming a University of Sanctuary with an event held on 16 May for all those who contributed to achieving this status. The University was awarded University of Sanctuary status in December 2022, joining a network of higher education institutions across the UK working to develop support for those displaced by humanitarian crises. The celebration was hosted by Aston University Vice-Chancellor and Chief Executive, Professor Aleks Subic. Guests included Councillor John Cotton, Birmingham City Council Cabinet member for Social Justice, Community Safety and Equalities, who made a special award presentation. The event programme also included a performance by poet Loraine Masiya Mponela, who herself was an asylum seeker and conversations with recipients of Ernest Edward Scholarships, a sanctuary scholarship scheme for students who have sought refuge in the UK. The scheme was set up by Aston University in 2022 due to a generous donation by prominent businessperson Matthew Crummack. Universities of Sanctuary is an initiative to recognise and celebrate the good practice of institutions welcoming people seeking sanctuary through facilitated access to higher education, supporting local refugee communities and taking an active role in learning about the issues and obstacles faced by this group in pursuing university-level education. Professor Aleks Subic, Vice-Chancellor and Chief Executive of Aston University, said: “I am delighted to have had this opportunity to host a celebration event to thank everyone who has helped us achieve the University of Sanctuary status. “Aston University is committed to supporting people seeking sanctuary through its efforts to deepen our understanding of the issues surrounding asylum seekers and refugees, providing a welcoming environment for sanctuary students, and working with individuals and communities beyond the campus to promote the values and principles of sanctuary. “Being a University of Sanctuary is key to our Civic Agreement: our commitment to make Birmingham a better place for everyone who lives, works, and studies here. Birmingham." Councillor John Cotton, Birmingham City Council Cabinet member for Social Justice, Community Safety and Equalities, said: “Birmingham is proud to be a City of Sanctuary, with its long history of offering refuge to those fleeing war, persecution and tyranny around the globe. In these troubled times, standing up for the principles of sanctuary and refuge is more important than ever. “I’m delighted that Aston University has joined the family of Universities of Sanctuary and is one of the many important institutions in our city that actively extends the hand of friendship to those seeking refuge and the chance to rebuild their lives here in Birmingham.”
Allen Friedland, M.D., MACP, FAAP, has been recognized with the Dema C. Daley Founders Award for his national impact as an educator, innovator and leader in internal medicine. Given by the Alliance for Academic Internal Medicine, the award honors internal medicine doctors who have greatly influenced undergraduate and graduate medical education and the development of training programs in internal medicine. Watch the video of Friedland’s acceptance speech here. “Dr. Friedland has been a tireless advocate and innovator for internal medicine, medicine-pediatrics, and residency education over two decades,” said Vinay Maheshwari, M.D., MHCDS, Hugh R. Sharp Jr., Chair of Medicine and physician executive of the Medical Group at ChristianaCare. “He is a mentor to countless physicians across the country and beloved by those who have had the privilege of working alongside him. What is most evident about Dr. Friedland is how much he cares about those he has taught locally and nationally – all of them will forever be a part of his family. This award is a testament to a lifetime career dedicated to graduate medical education.” Friedland is ChristianaCare’s section chief of Medicine-Pediatrics (Med-Peds) and has served as the director of ChristianaCare’s combined Internal Medicine-Pediatrics residency program for 25 years. He also teaches medical students at ChristianaCare, which is a branch campus of Sidney Kimmel Medical College at Thomas Jefferson University and Philadelphia College of Osteopathic Medicine. His accomplishments include: Spearheading the development of what is now known as ChristianaCare’s Center for Special Health Care Needs, dedicated to providing primary care and specialty care for adults ages 18 and older with complex medical and social conditions that originated in childhood. Creating the elective Leadership Excellence Education for Residents/Fellows (LEED-R), which partners emerging resident leaders with ChristianaCare senior leaders for mentorship, real-world experience in applying leadership education and the ability to share those learnings with other residents. Known affectionately by his colleagues as “Mr. Med-Peds,” Friedland has held leadership positions with all of the major national med-peds organizations. He co-founded the Med-Peds Academic Channel and received the Leadership Award from the Medicine-Pediatrics Program Directors Association. He recently launched a professional association named the Association of Med-Peds Physicians. Kimberly Bates, M.D., FACP, FAAP, director of the Internal Medicine Residency Program at Dignity Health – St. Rose Dominican, nominated Dr. Friedland for the award. Bates is a ChristianaCare Med-Peds alumna (Class of 2003). “Dr. Friedland is an exceptional human being and a natural leader and mentor who leaves a powerful imprint on every person he meets, whether they are students, residents, physician colleagues or patients,” Bates said. “He has dedicated his career to medical education, and he takes an innovative and problem-solving approach to all that he does.”
King Charles and the Power of Pomp
With the approach of the first coronation of a British monarch in 70 years, the world is watching, dissecting, and analyzing every element involved in the Coronation of King Charles III and his wife, Camilla, the Queen Consort. Cameras, photographers and journalists from across the globe are working overtime on this historic event, as are observers and scholars, including UConn anthropologist Dimitris Xygalatas, who penned a piece for the BBC where he explains the power behind the pomp and ceremony around the crowing of Britain's new king: On 6 May, 2023, one of the most spectacular rituals in the world will take place: the Coronation of King Charles III and his wife, Camilla, the Queen Consort. Shrouded in spectacle and adorned with priceless regalia, the ceremony will be officiated by the Archbishop of Canterbury at Westminster Abbey and attended by a host of foreign royals and heads of state. The whole event will be broadcast around the world, with hundreds of millions of people expected to tune in. Once crowned, the royal couple will return to Buckingham Palace in the Gold State Coach, a carriage so loaded with gold that it needs eight horses to pull it. They will be escorted by thousands of troops from all branches of the armed forces, making up the largest military display in three generations. The festivities will last all weekend – and a long weekend at that, as Monday has been proclaimed a public holiday nationwide. Events include colourful parades, public concerts, spectacular light shows, and thousands of street parties across the UK and the Commonwealth. The scale of this undertaking might seem exuberant. After all, King Charles may have dominion over all swans, dolphins, whales and sturgeons in the UK's waters but he will wield little political power beyond a largely ceremonial role. What is more, a coronation is not even necessary to become king. In fact, Edward VIII reigned as sovereign without ever being crowned. As heir apparent, King Charles III's accession to the throne occurred automatically the moment Queen Elizabeth II died, on 8 September 2022. ... The effects of ceremonial opulence may extend well beyond the Kings’ subjects. To the world at large, they act as status symbols – what anthropologists call “credibility-enhancing displays”. Our minds intuitively link effort with value. A ceremony that requires such enormous cost and effort to organise provides tangible evidence of the importance of the institution it celebrates and people’s commitment to that institution. At a time of political instability, with an increase in Russian aggression, the UK emerging from Brexit and a global pandemic, the British state could use some of that social glue. And above all, so could the royal family. The last few years have been rough on the royals, to say the least. Prince Andrew lost his military titles and royal patronages as he faced allegations of sexual assault that he has consistently denied. Internationally, as the world grapples with the legacy of colonialism, more and more countries seem inclined to cut their ties to the Crown. All the while, Prince Harry and his wife Meghan, the Duchess of Sussex, have had a very public exit from the centre of royal life and their media presence has been rubbing salt to these wounds. In light of these developments, the Coronation may play a crucial role in the Royal Family’s struggle to stay relevant. Indeed, as public support for the monarchy has been steadily declining, two recent grand ceremonies, the Queen’s Platinum Jubilee and funeral, have been accompanied by boosts to British attitudes towards the institution. King Charles III's Coronation will be one of the most grandiose royal celebrations of this century. It remains to be seen whether it can help convince his subjects that he still has a role to play in British society. Dimitris Xygalatas is an associate professor of anthropology and psychological sciences, and head of UConn's Experimental Anthropology Lab, which develops interdisciplinary methods and technologies for studying behavior in real-life settings. He is available to speak with media, answering all your questions about coronations and their rituals and purpose. Click on his icon to arrange an interview today.
Coronation of King Charles III: Augusta University professor talks about what to expect
Eyes from around the world will be on Westminster Abbey in London this weekend as King Charles III is crowned king following the passing his mother Queen Elizabeth II on Sept. 8, 2022. As you might expect, there will be plenty of pageantry involved with the ceremony. Ruth McClelland-Nugent, PhD, is chair of History, Anthropology and Philosophy at Pamplin College of Arts, Humanities, and Social Sciences at Augusta University and an expert on the royal family. McClelland-Nugent said this is a major day for those in the United Kingdom, and to a lesser extent, some parts of the Commonwealth "where the British monarch is still monarch, such as Charles will become king of Canada as well as the U.K." The coronation is a religious service of the Church of England, so there will be a number of traditions upheld, such as anointing of the king with blessed oil, and by the end of the ceremony, Charles will have officially received his crown and his scepter, as well as the traditional robes and stole that mark him as king. The crown and the orb that will be used during the coronation date back to 1661 for King Charles II. New crowns were needed after the Puritans melted the old ones down during the English Civil Wars. “These are very traditional things, and reinforce the ancient idea that the monarch is selected by God to have authority over people,” said McClelland-Nugent. "However, for the first time, there will be participation from clergy of other faiths as well, since the king has invited clergy from the Jewish, Sikh, Hindu, Muslim and Buddhist faiths to participate, reflecting the great religious diversity in the U.K.” She also said those watching the coronation, in-person or virtually, will be invited to swear an oath of allegiance to the monarch, giving the entire country a role in the ceremony for the first time. “It will probably feel very formal and ancient to any Americans who watch it, and it is, but it will be the most informal and diverse coronation in recent British history,” McClelland-Nugent said. Others in the royal family will also play roles in the ceremony. Queen Camilla will be crowned alongside Charles. Princess Anne, Charles' sister, will lead a procession of armed forces and other personnel behind the new king and queen when they leave Westminster Abbey. “Look for her to be on horseback. This is a highly prestigious role and not one carried out by a woman previously.” McClelland-Nugent said Prince William, Prince of Wales, who is now heir to the crown, will make an oath of loyalty directly to the newly crowned king. Some of the king’s grandchildren and queen’s grandchildren will also serve roles during the coronation. If you're a reporter covering the coronation and all the events leading up to it this week, then let our experts help with your stories. Ruth McClelland-Nugent is available for interviews; simply click on her icon now to arrange a time to talk today.
Is there a link between CTE and mass shootings? Let our expert explain
This spring news of mass shootings has dominated the headlines almost weekly with stories of tragedy in Michigan, Tennessee, Kentucky and Alabama. To date, there have been an estimated 160 mass-shootings in America this year. In the wake of each tragedy, Americans are left asking 'How this could happen?' and 'Why did this happen?' In the case of the April 10 shooting in Louisville, the parents of the gunman are also seeking answers as they claim prior trauma and CTE may have played some part in the shooter's actions and motivation. It's a theory that's getting a lot of attention from doctors and journalists. The family of Connor Sturgeon – who was killed after he fatally shot five people Monday morning at the Old National Bank in Louisville, Kentucky – plans to have his brain tested for chronic traumatic encephalopathy, commonly known as CTE, his father and a spokesperson for the family told CNN on Thursday. “Yes, Connor is being tested for CTE. Probably will take a while to get results,” Todd Sturgeon, Connor Sturgeon’s father, texted to CNN. Pete Palmer, a family friend who is speaking for the Sturgeons, said the family and the state medical examiner are looking to have Connor Sturgeon’s brain tested. April 14 - CNN There's a lot to know when reporting on CTE, especially when it involves the potential links to tragedy and a mass shooting. And that's where clinical experts can help and make sure reporters have the details, terminology and facts correct when covering such important topics. With over 40 years of clinical practice, Wayne Hulon is an American Board Certified Psychotherapist, and is also recognized by the State of Georgia as a Licensed Professional Counselor. In addition to his private practice, Wayne serves as a member of the American College of Psychotherapy and is currently serving as its Executive Director. Wayne is available to speak with media regarding this subject - simply click on his icon now to arrange an interview today.
Georgia Southern recognized as top 100 degree producer for diverse students
Georgia Southern University has ranked in the top providers nationally for degrees conferred to diverse students among higher education institutions. For several years, Diverse Issues In Higher Education has produced the Top 100 Degree Producers rankings of the institutions that confer the most degrees to diverse students. The data was reported at the end of 2022 for the previous year of 2020-2021. Georgia Southern ranked highly in the following categories: #2 for international (temporary resident) students receiving doctoral degrees in public health #3 for African American and total minority students receiving doctoral degrees in public health #5 for African American students receiving bachelor’s degrees in the physical sciences #6 for African American students receiving bachelor’s degrees in communications disorder sciences #6 for African American students receiving bachelor’s degrees in parks and recreation “We are proud to be ranked in the top 20 in a variety of disciplines and categories,” said Dominique A. Quarles, Ph.D., associate vice president for inclusive excellence and chief diversity officer. "Along with our designations as a First-gen Forward Institution and Military Friendly School, this highlights the University’s success in providing education to students in our diverse state and region, and it reaffirms the importance of inclusion as a value at Georgia Southern.” The number of combined bachelor’s, master’s and doctoral degrees awarded increased by over 55,000 degrees from 2019-2021 to 2021-2022 for diverse students nationwide. Underrepresented students of color received 35% of the combined degrees. The data comes from the Integrated Postsecondary Education Data system survey known as IPEDS, which are collected by the U.S. Department of Education. Georgia Southern detailed diversity rankings: Rank Category Degree Level Discipline #2 Temporary Resident Doctorate Public Health #3 African American Doctorate Public Health #3 Total Minority Doctorate Public Health #5 African American Bachelor’s Physical Sciences #6 African American Bachelor’s Communication Disorders Sciences #6 African American Bachelor’s Parks, Recreation, Leisure #8 African American Bachelor’s Engineering #9 African American Bachelor’s Marketing #10 African American Bachelor’s Rehabilitation and Therapeutic Sciences #13 African American Bachelor’s Finance #13 African American Master’s Parks, Recreation, Leisure #14 African American Bachelor’s Family And Consumer Sciences #14 Two or More Races Bachelor’s Communication Disorders #15 African American Bachelor’s Education #19 African American Bachelor’s All Disciplines Combined View the Top 100 Diverse Report Here For more information about the Top 100 Diverse Report or to speak with Dominique A. Quarles — simply reach out to Georgia Southern Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
#ExpertPerspective: Did the Covid-19 Pandemic Change Perspectives on Inequality?
Did the COVID-19 pandemic have a silver lining? According to Professor Andrea Dittmann and an interdisciplinary team of researchers, the answer is, “Yes.” In 2020, when it became clear that the COVID-19 pandemic would upend daily life, Andrea Dittmann decided the research she’d been doing could wait. Typically, Dittmann, Assistant Professor of Organization & Management, studies the sources of—and solutions to—inequality in the workplace. “The pandemic is a very distressing thing, but from a research standpoint it’s fascinating to study,” Dittmann said. “The pandemic laid bare all of the inequalities that I’ve been studying for years.” Dittmann, along with colleagues Ellen Reinhart and Hazel Rose Markus from the Department of Psychology, Stanford University; Rebecca Carey, Department of Psychology, Princeton University; Nicole Stephens, Management and Organizations, Northwestern’s Kellogg School of Management; and Hannah Birnbaum, Organizational Behavior Area, Olin Business School at Washington University in St. Louis, decided to study how experiencing personal harm as a result of the Covid-19 pandemic influenced people’s attitudes and behaviors towards equality. In their paper, “Personal Harm from the Covid-19 pandemic predicts advocacy for equality,” published in the January 2023 issue of Journal of Experimental Social Psychology, the researchers write that experiencing greater personal harm in the early stages of the pandemic was “associated with increased advocacy for equality one year later.” These findings are noteworthy. For decades, psychologists have studied Americans’ tendency to rationalize existing inequality as a consequence of individual or “internal” attributes (e.g. differences in work ethic) rather than as a product of larger structural, external, and uncontrollable factors such as bad luck, discrimination, or differences in educational opportunities. “Americans tend to explain people’s life outcomes as free from the constraints of history, other people, and social systems. Instead, life outcomes are seen as a product of individuals’ personal preferences, choices, or enduring characteristics,” they write. Lessons from Firsthand Experience While previous studies have shown that increasing a person’s exposure to inequality—for instance, working in an under-served school or participating in a poverty simulation—can increase people’s endorsement of external attributions for inequality, the COVID-19 pandemic presented the researchers with a real life opportunity to test their hypothesis: that an individual’s firsthand experience of personal harm due to an external force beyond his or her control “will be associated with an increase in their advocacy for equality over time,” they write. Firsthand exposure to inequality confronts people with information contrary to the dominant narrative; it demonstrates how forces beyond individuals’ control can shape people’s opportunities. To conduct their study, the authors recruited a balanced sample (in terms of gender and educational level) of approximately 1500 U.S. citizens between the ages of 18-70. Over the course of a year, they surveyed the participants three times—in May 2020, October 2020 and May 2021. Participants were asked whether they had experienced personal harm as a result of the pandemic (such as disruptions to sleep, poor mental health, financial difficulties, contracting the disease, or having a friend/family member die from the disease) and whether or not experiencing such harm was associated with greater endorsement of external attributions for inequality. Increased Advocacy: A Silver Lining To measure attitudinal and behavioral advocacy for equality, the study included questions about whether there should be universal healthcare, whether the government should provide stimulus checks to help people meet basic needs, and whether or not participants had done anything to combat inequality as a result of the personal harm they had experienced. Had they contacted a public official to express support for reducing social or economic inequality? Had they posted or shared content online that related to reducing social or economic inequality? Even when we ran the most conservative statistical tests, we were still seeing this meaningful relationship between experiencing personal harm and changing your attitude towards inequality and being more willing to stand up and do something about inequality. It speaks to the importance of having direct experience with something that has a disproportionate effect on your life. Dittmann doesn’t know if these attitudinal shifts will be permanent, but she believes the results of the study suggest that research interventions, like asking people to think about people they know who are affected by “large, external shocks” such as climate change or a natural disaster, “could be a way, experimentally, to get more people to see the link, to make these external attributions,” she explained. “While it’s of course awful that so many people experienced this harm due to the pandemic, if there is one good thing that came of it, people were able to shift their attitudes towards inequality. And very importantly, as someone who has done a lot of social psychological research, you don’t expect these effects to persist this long over time. They tend to be more transient. But this study suggests that these could be relatively long term effects.” Looking to know more? Then let us help with your media coverage or research. Andrea is an Assistant Professor of Organization & Management at Emory University's Goizueta Business School. She studies diversity and inequality, particularly employees' social class backgrounds, aiming to promote equity and inclusion at work. Andrea is available to speak with media - simply click on her icon now to arrange an interview today.
• Researchers in the School of Biosciences partner with preclinical-stage biotechnology start-up company to develop drugs for fibrotic diseases • Professor Martin Griffin and team develop TG2 inhibitors to help treat a serious chronic lung disease called idiopathic pulmonary fibrosis. • Isterian Biotech is part of Cambrian BioPharma who have been working with Aston University since 2019. Aston University scientists are working with start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease. The focus of preclinical-stage biotechnology company Isterian Biotech is on developing novel drugs to stop or reverse the pathological accumulation of crosslinked proteins commonly observed in all major organs with age. As we age a chronic increase of crosslinked proteins occurs in the extracellular matrix (ECM), that surround, support, and give structure to the cells and tissues in the body. These crosslinked proteins are difficult for the body to degrade and over time can make organs stiff and dysfunctional, ultimately resulting in fibrosis. Reversing the accumulation of these pathological crosslinks will greatly contribute to reducing fibrosis. The start-up is working to develop small molecule inhibitors of transglutaminase 2 also known as TG2, which is one of the major crosslinking enzymes in the human body, that becomes more active during ageing - thus resulting in fibrotic diseases such as a type of lung disease known as idiopathic pulmonary fibrosis (IPF). Isterian President and Chairman of the Board, Georg C Terstappen, PhD said: "Isterian's strategy of combining rational drug design with efficient multiparametric profiling of synthesized small molecules has been both impressive and highly productive. Notably, for one of our highly potent and selective TG2 inhibitors, we have recently demonstrated efficacy in a mouse model of lung fibrosis for the first time. "Using this state-of-the-art approach to drug discovery combined with an impressive team gives us great confidence in the future of this novel company." IPF is a progressive, irreversible disease that is characterized by pathological crosslinking of extracellular matrix (ECM) proteins (a large network of proteins and other molecules that surround, support, and give structure to the cells and tissues in the body) leading to excessive deposition of collagen. This means that in IPF scar tissue or fibrosis builds up around the air sacs (alveoli) in the lungs and reduces the ability to transfer oxygen that is breathed into the blood, resulting in severe restriction of lung capacity and function. IPF is the most common form of pulmonary fibrosis. The disease affects between 200,000 and 300,000 people globally. Statistics from the charity Action for Pulmonary Fibrosis suggest there are about 30,000 people living with IPF in the UK with an estimated 6,000 new cases of the condition each year. The disease usually develops in people aged 70 and older and is more common in men. But it can occur in younger individuals, particularly if there is a family history of idiopathic pulmonary fibrosis. The company was founded by capitalizing on over 35 years of scientific research from the laboratory of Professor Martin Griffin and his team Dr Dan Rathbone and Dr Vivian Wang at Aston University. Their work with small molecule inhibitors selective for TG2 has demonstrated reduction of fibrosis in multiple organs in a number of animal models. In 2019, Aston University partnered with Cambrian to form Isterian Biotech with a mission to develop safe and effective TG2 inhibitors to treat Idiopathic pulmonary fibrosis (IPF), a devastating fibrotic disease of the lung. Professor Martin Griffin, Biosciences Research Group, Aston University said: “We are delighted to continue our work with Isterian researching how we can further develop TG2 inhibitors to help tackle this awful disease.” CEO of Cambrian BioPharma, James Peyer, commented: "As Cambrian continues on its mission to build medicines that will redefine healthcare in the 21st century, we are very thankful to find brilliant scientists such as Martin and his team that are willing to break the mold. Isterian and its work to reduce fibrosis are a perfect fit alongside the other pipeline companies our team has announced in 2022." The company's current pipeline includes an advanced preclinical-stage TG2 inhibitor for inhaled administration and several structurally unrelated back-up compounds for the treatment of IPF. For more information about the School of Biosciences at Aston University, please visit our website.