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New research suggests model organisms may have evolved too far
A research team from Aston University and the Universities of Birmingham and Nottingham suggest model organisms evolved over 100 years may no longer be fit for purpose They found the bacterial strain Escherichia coli K-12 has been repeatedly cultured and mutated, resulting in many genetic changes The study has just been published in Microbial Genomics A research team from Aston University has found that the model organism used in laboratories for the past 100 years has evolved so extensively that it may no longer be fit for purpose. According to a new study, published in Microbial Genomics, the bacterial strain Escherichia coli K-12 has been repeatedly cultured and mutated, resulting in an organism that carries many genetic changes compared to the original isolated bacteria. The research team, from Aston University, and the Universities of Birmingham and Nottingham, made their discovery after re-examining the early preserved samples and looking at the base sequence of their DNA. They found a large number of differences at the DNA sequence level, and the differences are bigger when they examined currently used stocks that derived from the original samples. The work underscores the dangers of using one strain as a sole model. It also confirms that bacterial sequences evolve over short time scales and provides a fascinating insight into the first baby steps of molecular microbiology. Lead author Dr Doug Browning, of the School of Biosciences at Aston University, said: “The past 10 years have seen a massive amount of bacterial genome sequencing and the picture that is emerging is that bacterial genomes change very fast. This was unimaginable 100 years ago, and, of course, this is why folk back then were quick to adopt the K-12 strain as the model for everything.” The strain of bacteria in the study was originally isolated in 1922 from the faeces of a recuperating diptheria patient at Stanford University, in California. The strain was preserved and over time it, and many derivatives, were distributed to research laboratories around the world for use by researchers looking to understand the workings of living cells at the molecular level. While the number of genetic variations which have appeared in the intervening decades may sound alarm bells in some research areas, for others it may represent new research opportunities. Co-author Steve Busby, of the Institute of Microbiology and Infection at the University of Birmingham, said: “Actually the diversity that all this generates can add a new dimension to our understanding. It’s often true that things are seldom as they seem, and particularly so if you only study one strain.”
Expert Comment - the humanitarian use of drones in the current Turkish/Syrian earthquake disaster
Dr Muhammad Azmat, Assistant Professor in Logistics and Supply Chain Management at Aston University, Birmingham, is available to provide comment on the humanitarian use of drones in the current Turkish/Syrian earthquake disaster, and why they should be used more. “There are several examples from the recent past that suggest autonomous drones and drone swarms could be an effective tool to speed up search and rescue operations. “I believe there is a need for more awareness of drones and humanitarian organisations should be encouraged in using this new technology.” Dr Azmat has previously written for The Conversation about the potential use of humanitarian drones during the Ukraine war Dr Azmat’s profile: Dr Muhammad Azmat Assistant Professor in Logistics and SCM - Expert with Aston University | ExpertFile If you have any queries, please contact Dr Azmat or Nicola Jones Mobile: (+44)7825 342091 n.jones6@aston.ac.uk Press and Communications Manager, College of Engineering and Physical Sciences, Aston University, Aston Triangle Birmingham, B4 7ET, UK
AI-Generated Content is a Game Changer for Marketers, but at What Cost?
Goizueta’s David Schweidel pitted man against the machine to create SEO web content only to find that providing an editor with bot-generated content trounces the human copywriter every time. Good news for companies looking to boost productivity and save cash, he says. But could there be other hidden costs? In December 2022, The New York Times ran a piece looking back on the year’s biggest consumer tech updates. The review was mixed. Ownership shifts in the world of social media garnered special mentions, but hardware innovations had been largely “meh,’ mused the Times. There was one breakthrough area that warranted attention, however: AI-powered language-processing tech capable of generating natural-looking text, the same technology that powers familiar chatbots. And one such technology could well be poised to “invade our lives in 2023.” Earlier in December, AI research lab OpenAI, released the latest update to its Generative Pre-Trained Transformer technology, an open source artificial intelligence. It’s latest iteration, ChatGPT, immediately went viral. Here was an AI assistant that sounded intelligent. Not only could it answer any question thrown its way without supervised training, but when prompted, it could also write blog posts, as well as find and fix bugs in programming code. ChatGPT could draft business proposals and even tell jokes. All of this at a speed that beggared belief. Since its first release in 2020, OpenAI’s GPT technology has powered through a slew of updates that have seen its capabilities leap forward “by light years” in less than 24 months, says Goizueta Professor of Marketing, David Schweidel. For businesses looking to harness this rapidly-evolving technology, the potential is clearly enormous. But aren’t there also risks that industry and consumers alike will need to navigate? Schweidel is clear that the academic community and initiatives such as the Emory AI Humanity Initiative have a critical role in asking hard questions—and in determining the limitations and dangers, as well as the opportunities, inherent in tech innovation—because, as he puts it, “these things are going to happen whether we like it or not.” Man Versus Machine To that end, Schweidel and colleagues from Vienna University of Economics and Business and the Modul University of Vienna have put together a study looking at how well natural language generation technologies perform in one specific area of marketing: drafting bespoke content for website search engine optimization, better known as SEO. What they find is that content crafted by the machine, after light human editing, systematically outperforms its human counterparts—and by a staggering margin. Digging through the results, Schweidel and his colleagues can actually pinpoint an almost 80 percent success rate for appearing on the first page of search engine results with AI-generated content. This compares with just 22 perfect of content created by human SEO experts. In other words, the AI content passed to a human is roughly four times more effective than a skilled copywriter working alone. Reaching these findings meant running two real-time, real-world experiments, says Schweidel. First, he and his colleagues had to program the machine, in this case GPT 2, an earlier incarnation of GPT. GPT relies on natural language generation (NGL), a software process that converts manually uploaded input into authentic-sounding text or content—comparable in some ways to the human process of translating ideas into speech or writing. To prepare GPT-2 for SEO-specific content creation, Schweidel et al. started with the pre-trained GPT-2, and then let the machine do the heavy lifting: searching the internet for appropriate results based on the desired keyword, scraping the text of the websites, and updating GPT-2 to “learn” what SEO looks like, says Schweidel. We partnered with an IT firm and a university to run our field experiments. This meant creating SEO content for their websites using GPT-2 and actual human SEO experts, and then doing A/B testing to see which content was more successful in terms of landing in the top 10 search engine results on Google. So this was an opportunity to put the AI bot to the test in a real-world setting to see how it would perform against people. The results point to one clear winner. Not only did content from GPT-2 outperform its human rivals in SEO capabilities, it did so at scale. The AI-generated content scored a daily median result of seven or more hits in the first page of Google search results. The human-written copy didn’t make it onto the first result page at all. On its best day, GPT showed up for 15 of its 19 pages of search terms inside the top 10 search engine results page, compared with just two of the nine pages created by the human copywriters—a success rate of just under 80 percent compared to 22 percent. Savings at Scale The machine-generated content, after being edited by a human, trounces the human in SEO. But that’s not all, says Schweidel. The GPT bot was also able to produce content in a fraction of the time taken by the writers, reducing production time and associated labor costs by more than 90 percent, he says. “In our experiments, the copywriters took around four hours to write a page, while the GPT bot and human editor took 30 minutes. Now assuming the average copywriter makes an annual $45K on the basis of 1,567 hours of work, we calculate that the company we partnered with would stand to save more than $100,000 over a five-year period just by using the AI bot in conjunction with a human editor, rather than relying on SEO experts to craft content. That’s a 91 percent drop in the average cost of creating SEO content. It’s an orders of magnitude difference in productivity and costs.” But there are caveats. First off, there’s the quality of the machine-generated content to consider. For all its mind-boggling capabilities, even the newly released ChatGPT tends to read somewhat sterile, says Schweidel. That’s a problem both in terms of Google guidelines and brand coherence. Human editors are still needed in order to attenuate copy that can sound a little “mechanical.” “Google is pretty clear in its guidelines: Content generated by machines alone is a definite no-no. You also need to factor in the uncanny valley effect whereby something not quite human can come off as weird. Having an editor come in to smooth out AI content is critical to brand voice as well as the human touch.” Asking the Big Questions Then there are the moral and metaphysical dimensions of machine learning and creativity that beg an important question: Just because we can, does that mean we should? Here, Schweidel has grave reservations about the future of ChatGPT and its ilk. The potential of this kind of technology is extraordinarily exciting when you think about the challenges we face from productivity to pandemics, from sustainable growth to climate change. But let’s be very clear about the risks, too. AI is already capable of creating content—audio, visual and written—that looks and feels authentic. In a world that is hugely polarized, you have to ask yourself: How can that be weaponized? At the end of the day, says Schweidel, the large language models powering these generative AIs are essentially “stochastic parrots:” trained mimics whose output can be hard to predict. In the wrong hands, he warns, the potential for misinformation—and worse—could well be “terrifying.” “Shiny new tech is neither inherently good nor bad. It’s human nature to push the boundaries. But we need to ensure that the guardrails are in place to regulate innovation at this kind of pace, and that’s not easy. Governments typically lag far behind OpenAI and companies like them, even academics have a hard time keeping up. The real challenge ahead of us will be about innovating the guardrails in tandem with the tech—innovating our responsible practices and processes. Without effective safeguards in place, we’re on a path to potential destruction.” Covering AI or interesting in knowing more about this fascinating topic - then let our experts help with your coverage and stories. David Schweidel is the Rebecca Cheney McGreevy Endowed Chair and Professor of Marketing at Emory University's Goizueta Business School. Simply click on David's icon now to arrange an interview today.
Researchers find mechanical stimulation could be used to help improve balance control The findings provide new information on whole-body vibration applications Paves the way for research on the interaction between the central nervous system and peripheral muscles. Mechanical vibrations could help improve our muscles and our balance control, according to research at Aston University. Researchers in the College of Engineering and Physical Sciences have examined the effect of stimulation on muscle spindles which ‘speak’ to the central nervous system to help keep us upright and walk straight. Their results provide new perspectives on whole-body vibration applications, paving the way for future research on the interaction between the central nervous system and the peripheral muscles. The research could in future be applied to improve balance in older people and help reduce falls, this could be applied through either wearable devices or with a daily session of stimulation. Hip fractures alone account for 1.8 million hospital bed days and £1.1 billion in hospital costs every year, excluding the high cost of social care. Another potential benefit of the research is that this type of stimulation could be applied to athletes to decrease their muscle reaction times. The goal of the study was to find out if mechanical vibrations can improve the way our bodies process and react to small body oscillations. Seventeen young male and female adult volunteers aged between 20 and 28 years old stood individually on platforms, similar to vibrating plates found in gyms, which caused leg muscle contractions. Calf muscles were targeted as the muscles whose action contribute the most to maintaining a stable upright posture. The researchers stimulated their calves with a frequency of 30Hz and recorded four one-minute trials of undisturbed balance to take a baseline measure and compared the readings to measurements taken after the stimulation. After conducting the experiment, they found that their balance seemed to have improved. The research, Sensorimotor recalibration of postural control strategies occurs after whole body vibration, was led by Dr Antonio Fratini, senior lecturer in mechanical, biomedical & design engineering, and PhD student Isotta Rigoni, and has been published in Scientific Reports – Nature. Dr Fratini said: “We’re excited by our results as they could have a beneficial effect on the health and quality of life of a large number of people. “Our results indicate that whole body vibration challenges balance at first, triggering a bigger effort to control the upright stance and shifting muscle modulation toward supraspinal control, resulting in a recalibration of muscle recruitment. The neuromuscular system seems to recover from such disruption and regain control over a longer time interval.” “Indeed, while muscle recruitment and cortical effort appear unaltered over the long term, the balance seems not only restored but also improved, besides the still clearly affected calf muscles.” For more information about our research or studying in the College of Engineering and Physical Sciences please visit our website.
Aston University AI expertise helps estimate daily transmission rates of infections such as Covid
Model used antibody data collected at blood donation centres Data obtained allowed academics to estimate the proportion of people who were going undiagnosed Current epidemiological models tend not to be as effective at estimating hidden variables such as daily infection rates. Aston University researchers have helped develop a mathematical model which can estimate daily transmission rates of infections such as Covid by testing for antibodies in blood collected at blood donation centres. Current epidemiological models that are usually used tend not to be as effective at adjusting quickly to changes in infection levels. Working with researchers at the Universidade Federal de Minas Gerais in Brazil they conducted a large longitudinal study applying a compartmental model, which is a general modelling technique often applied to the mathematical modelling of infectious diseases, to results obtained from Brazilian blood donor centres. The testing was done by Fundacao Hemominas, one of the largest blood services in Brazil, which covers an area similar to that of continental France. They used the reported number of SARS-CoV-2 cases along with serology results (diagnostic methods used to identify antibodies and antigens in patients’ samples) from blood donors as inputs and delivered estimates of hidden variables, such as daily values of transmission rates and cumulative incidence rate of reported and unreported cases. The model discussed in the paper SARS-CoV-2 IgG Seroprevalence among Blood Donors as a Monitor of the COVID-19 Epidemic, Brazil gave the experts the ability to have a more refined view of the infection rates and relative rate of immunity compared to official measurements. The testing started at the beginning of the pandemic and involved 7,837 blood donors in seven cities in Minas Gerais, Brazil during March–December 2020. At that point testing wasn’t widely available and there was a high proportion of undetected asymptomatic or light symptomatic cases. The data obtained allowed the experts to estimate the proportion of people who were going undiagnosed. Dr Felipe Campelo, senior lecturer in computer science at Aston University, said: “Public communication about the COVID-19 epidemic was based on officially reported cases in the community, which strongly underestimates the actual spread of the disease in the absence of widespread testing. “This difference underscores the convenience of using a model-based approach such as the one we proposed, because it enables the use of measured data for estimating variables such as the total number of infected persons. “Our model delivers daily estimates of relevant variables that usually stay hidden, including the transmission rate and the cumulative number of reported and unreported cases of infection.” In Brazil in July 2020 there was a sharp increase in the number of people tested as new infrastructure became available, which allowed the experts to further validate their methodology by observing how officially recorded data became closer to the model predictions once testing became more widespread, including for asymptomatic or mildly symptomatic people. They applied the model to antibodies found in blood given by donors and used it to estimate the proportion of undiagnosed cases, and to analyse changes in the infection rate, that is, how many people each case infected on average. Previously this has been viewed as a fixed value or a fixed value over a long duration of time, but the dynamics of the spread of Covid change much faster than that. This aspect was very important in early days of the pandemic and could also be applied to similar diseases. Looking forward, the experts aim to improve the accuracy of the model by introducing changes to account for vaccination effects, waning immunity and the potential emergence of new variants. The paper SARS-CoV-2 IgG Seroprevalence among Blood Donors as a Monitor of the COVID-19 Epidemic, Brazil has been published in Volume 28, Number 4—April 2022 of Emerging Infectious Diseases.
Birmingham City Council Cabinet Member Cllr Majid Mahmood met with sustainability experts from across Aston University Cllr Mahmood is responsible for the city’s sustainable waste strategy Knowledge exchange projects between the city council and Aston University were discussed. Birmingham City Council’s Cabinet Member for Environment visited Aston University on 30 November to meet with academics working on sustainability challenges. Cllr Majid Mahmood is responsible for developing a financially and environmentally sustainable waste strategy for the city and engaging in citywide and national policy development to tackle the causes and consequences of climate change, among other accountabilities. Cllr Mahmood’s visit included seeing the chemical engineering and applied chemistry labs run by Dr Jiawei Wang and Dr Matthew Derry who are investigating methods for generating energy from waste and creating new, more sustainable materials. He also met with Professor Patricia Thornley, director of the Energy Bioproducts Research Institute (EBRI) along with other colleagues including Dr Katie Chong, who showcased EBRI’s world-leading research into bioenergy and bioproducts and heard from Dr Luciano Batista on the work he is leading at the Centre for Circular Economy and Advanced Sustainability which provides practical answers to tackle world-critical sustainability challenges. During the visit, Cllr Mahmood was able to share some of the challenges and opportunities facing Birmingham City Council, particularly around sustainability, the environment and waste management. He discussed with academics how Aston University’s research could feed into Birmingham City Council’s future waste and energy management plans and how the lived experience of the city should shape the direction of research. A number of knowledge exchange opportunities were also discussed, including using the city council’s experience to develop undergraduate student projects and academics being invited to visit Birmingham’s waste management depots. Cllr Majid Mahmood said: “It has been brilliant to visit Aston University today and to learn about the innovative ways that different academics are tackling the sustainability challenges facing the world. “As the largest metropolitan local authority in the UK, Birmingham is uniquely placed to develop sector leading waste and energy management processes. Working closely with universities like Aston University will help us to achieve this. “I look forward to developing our working relationship and combining our practical experience and research excellence to drive innovation in the sector.”
Aston University to help power Indonesia with affordable energy made from rice straw
Project to convert unwanted rice straw into cheap energy on a commercial scale Most rice straw in Indonesia is burned causing pollution and health problems Project will almost double affordable energy captured from waste. Scientists at the Energy and Bioproducts Institute at Aston University are to start a project to convert Indonesia’s unwanted rice straw into low-cost energy on a commercial scale. Each year the country produces 100 million tonnes of the rice waste, of which 60% is burned in open fields, causing air pollution and has even been linked to lung cancer. The amount burned is equivalent to approximately 85 Terawatts of electricity, which is enough to power Indonesia’s households 10 times over. A consortium which includes Aston University aims to develop processes to capture more affordable energy from rice straw than ever before - and demonstrate that it can be done on a commercial scale. Part of the process involves a biomass conversion technology called pyrolysis. This involves heating organic waste materials to high temperatures of around 500 °C to break them down, producing vapour and solid products. Some of the vapour may be condensed into a liquid product called pyrolysis oil or pyrolysis bio-oil. Both the pyrolysis vapour and liquid bio-oil can be converted to electricity. Current methods convert just 35% of the thermal energy of rice straw to affordable electricity. However, a newly patented combustion engine designed by consortium member, UK-based Carnot Limited, could see that doubled to 70%. Energy extracted this way could help low and middle-income countries create their own locally generated energy, contribute to net zero by 2050, create new jobs and improve the health of locals. The project will help develop a business model which could support companies and local authorities to produce local, cheap energy in Indonesia, and other countries with biomass capacity. Three academic experts from different disciplines at Aston University are involved in this initial project, which focuses on Indonesia’s Lombok Island. Dr Jude Onwudili, Dr Muhammad Imran and Dr Mirjam Roeder are based at Aston University’s Energy and Bioproducts Research Institute (EBRI). Dr Jude Onwudili who is leading the team said: “This project has huge potential - commercialisation of this combined technology will have significant economic benefits for the people of Indonesia through direct and indirect job creation, including the feedstock supply chain and electricity distribution and sales. “About one million Indonesian homes lack access to energy and Indonesia's 6,000 inhabited islands make sustainable infrastructure development challenging in areas such as Lombok Island. “The new techniques being explored could reduce environmental pollution, contribute to net zero and most importantly, provide access to affordable energy from sustainable local agricultural waste. “Aston University is a global leader in bioenergy and energy systems, and I am delighted we received funding to explore this area.” Over a power plant’s life, the project team have calculated that biomass produces cheaper electricity (approx. $4.3$/kWh) compared to solar (approx. $6.6/kWh), geothermal (approx. $6.9/kWh), coal (approx.$7.1/kWh), wind (approx. $8/kWh) and subsidised gas (approx.$8.4ckWh). The project will start in April 2023 with a total of £1.5 million funding for the four partners from Innovate UK. Alongside Carnot Limited, the Aston University scientists will be working with two other UK-based businesses to deliver the project, PyroGenesys and Straw Innovations. PyroGenesys specialises in PyroChemy technology which will convert 70% of the rice straw into vapour or bio-oil for electricity production, with the remainder converted into nutrient-rich biochar, which can be sold back for use as fertiliser on the rice farms. Straw Innovations will contribute their rice straw harvesting and collection expertise, with their many years of similar operations in Asia.
First ever computer reconstruction of a virus, including its complete native genome Will open way for investigating biological processes which can’t currently be fully examined because the genome is missing Could lead the way to research into an alternative to antibiotics. An Aston University researcher has created the first ever computer reconstruction of a virus, including its complete native genome. Although other researchers have created similar reconstructions, this is the first to replicate the exact chemical and 3D structure of a ‘live’ virus. The breakthrough could lead the way to research into an alternative to antibiotics, reducing the threat of anti-bacterial resistance. The research Reconstruction and validation of entire virus model with complete genome from mixed resolution cryo-EM density by Dr Dmitry Nerukh, from the Department of Mathematics in the College of Engineering and Physical Sciences at Aston University is published in the journal Faraday Discussions. The research was conducted using existing data of virus structures measured via cryo-Electron Microscopy (cryo-EM), and computational modelling which took almost three years despite using supercomputers in the UK and Japan. The breakthrough will open the way for biologists to investigate biological processes which can’t currently be fully examined because the genome is missing in the virus model. This includes finding out how a bacteriophage, which is a type of virus that infects bacteria, kills a specific disease-causing bacterium. At the moment it is not known how this happens, but this new method of creating more accurate models will open up further research into using bacteriophage to kill specific life-threatening bacteria. This could lead to more targeted treatment of illnesses which are currently treated by antibiotics, and therefore help to tackle the increasing threat to humans of antibiotic resistance. Dr Nerukh said: “Up till now no one else had been able to build a native genome model of an entire virus at such detailed (atomistic) level. “The ability to study the genome within a virus more clearly is incredibly important. Without the genome it has been impossible to know exactly how a bacteriophage infects a bacterium. “This development will now allow help virologists answer questions which previously they couldn’t answer. “This could lead to targeted treatments to kill bacteria which are dangerous to humans, and to reduce the global problem of antibiotic-resistant bacteria which are over time becoming more and more serious.” The team’s approach to the modelling has many other potential applications. One of these is creating computational reconstructions to assist cryo-Electron Microscopy – a technique used to examine life-forms cooled to an extreme temperature.
Aston University bioenergy researchers to improve measurement of industrial carbon dioxide
Researchers at Aston University are to take the UK a step nearer to net zero emissions by developing a better system of measuring industrial carbon dioxide. The government is giving the University £100,000 to improve measurement of CO2 streams from sites such as at power plants and factories. The Energy and Bioproducts Research Institute (EBRI) at Aston University is to develop a comprehensive guide based on industry and academic expertise. Industrial decarbonisation will play a major role in achieving the UK’s 2050 ambitious net zero emissions target, however current measurement guidelines need to be improved. The six-month project will be a collaboration between EBRI researchers and the company Progressive Energy and the Energy Institute. Progressive Energy will work alongside potential end-users and the Energy Institute will help to ensure the final guidelines are clear. The work is being led by Dr Paula Blanco Sanchez, who has more than 15 years of experience in bioenergy. She said: “This funding will help Aston University to address a major gap in the decarbonisation pathway. It will contribute to the UK’s net zero target and is another example of how the University is using its expertise to tackle real world problems. “Our experts in EBRI will provide research, industrial experience and knowledge in areas such as gas measurement, metric and analytics, life cycle and techno-economic assessments, and thermal conversion processes.” The funding has been awarded by the Industrial Decarbonisation Research and Innovation Centre (IDRIC) to achieve the net zero ambition set out in the UK Industrial Decarbonisation Strategy (2021). Bryony Livesey, challenge director, Industrial Decarbonisation Challenge, UKRI, said: “The announcement of this funding continues to build upon IDRIC’s whole system approach to decarbonising industry, enabling the UK to remain at the forefront of a global low-carbon future. These successful Wave 2 projects will build evidence on a range of areas from economics and emissions to skilled jobs and wider net zero policy, supporting UK’s green growth and net zero ambitions.” It’s hoped the Aston University project will lead to future collaborations and funding to support UK industry to decarbonise their businesses. In May, June and September the EBRI plant will be opening its doors to professionals who want to enhance their careers with a short hands-on course in Practical Process Engineering. For more information visit https://www.aston.ac.uk/study/courses/practical-process-engineering
Aston University to celebrate 100 years of pharmacy education and research
Aston Pharmacy School to celebrate 100 year anniversary during 2023 The history of teaching pharmacy at Aston University dates back to the 1890s In 2016 the Pharmacy School was awarded a Regius Professorship by HM Queen Elizabeth II. Aston University is gearing up to celebrate 100 years of pharmacy education and research this year. In 1923 the Birmingham Municipal Technical School started to offer full time pharmacy courses to applicants from the general public. The roots of pharmacy education at Aston University date back to the 1890s and more significantly to 1919 when it first started teaching the subject as part of the Chemistry department at the Birmingham Municipal Technical School - as part of a funded package of training and education for returning servicemen after the First World War. In 1923 the pharmacy training provision expanded, taking on six specialist pharmacy staff within the pharmacy section of the Department of Chemistry. That year the Technical School began to offer full time pharmacy courses open to applications from the general public. In 1926 Harry Berry was appointed as head of a separate Department of Pharmacy - following an inspection by the University of London and a positive report. This distinct identity was further cemented a year later in 1927, when Neville Chamberlain, who was the then Minister for Health, opened the new teaching facilities in the School of Pharmacy in the Birmingham Central Technical College. Since then, the University has graduated thousands of pharmacy students with more than 2700 graduates in the last 20 years. Aston University’s Pharmacy School is now recognised as one of the outstanding pharmacy schools in the UK and has been at the forefront of scientific advances over the last 100 years. Its researchers developed the $2 billion blockbuster drug Temozolomide, the leading treatment for brain tumours and it created the UK's first Masters programme for hospital pharmacists. In 2016, Aston Pharmacy School was awarded a Regius Professorship by HM Queen Elizabeth II to mark her 90th birthday. It was the first time a pharmacy school had been given the award, a rare and prestigious honour bestowed by the Sovereign to recognise exceptionally high-quality research. The first holder of the title of Regius Professor of Pharmacy at Aston University was Keith Wilson, a pharmacy academic who helped to shape current and future pharmacy education both within the UK and internationally. Dr Joe Bush, head of Aston Pharmacy School, at Aston University said: "100 years of pharmacy education is a major milestone. We are immensely proud of all our achievements, from producing exceptional graduates who make a significant contribution to the professional workforce in a variety of near-patient settings, to our research discoveries and developments which have positively impacted patient healthcare and the high quality of this research having been recognised via the award of the first ever Regius Chair for Pharmacy. “It is an honour to be a part of Aston Pharmacy School, whose humble beginnings have grown to produce world class research and exceptional graduates. I look forward to celebrating with the rest of the school over the course of the year.” Celebrations of the centenary anniversary will include a celebratory lunch for staff, former staff, students and alumni to recognise the significant contributions that the school has made in research discoveries and teaching. The school will host an exhibition about the last 100 years of pharmacy at Aston University, with a range of historical artefacts on display in the entrance to the University’s main building and there will be a social media campaign to highlight key facts about the last 100 years of pharmacy at Aston University. Did you study pharmacy at Aston University? We would love to hear from you with any stories, memories from your student days. And we would love to hear about where your pharmacy career has taken you. Please get in touch with our alumni team here.