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Aston University student and graduate business startup support programme marks 10th year
BSEEN is a collaboration of four Birmingham universities, led by Aston University It has helped over 800 new businesses to launch through intensive startup bootcamps and a network of business mentors An awards dinner was held on 4 May to celebrate a decade in operation. An Aston University student and graduate business startup support programme has celebrated its 10th year in operation. BSEEN, a collaboration of four Birmingham universities led by Aston University, marked a decade of supporting student and graduate entrepreneurs with an awards dinner on 4 May 2023. Mike Bander, an Aston University alumnus and recipient of an honorary doctorate, was guest speaker and gave a keynote speech. The programme has helped over 800 new businesses to launch through 31 intensive startup bootcamps and a network of 85 business mentors. The awards night at Fazeley Studios in Birmingham showcased the student and graduate entrepreneurs supported by BSEEN and the mentors and professional services organisations who have worked to help startups through surgeries, drop-ins and round table discussions. Mike Bandar, international business trainer and speaker and founding partner of Turn Partners, said: “The power of the collective community has changed “I” into “us”. Personal ambition is essential, but the true spirit of entrepreneurship is to unite, collaborate and transform. Diversity gives us strength by not seeing competitors as rivals, but partners.” Professor Zoe Radnor, pro-vice chancellor and executive dean of the College of Business and Social Sciences at Aston University, said: “I have heard so much about BSEEN that was amazing and I am looking forward to supporting young people to achieve their goals despite European funding for the scheme coming to an end.” Paula Whitehouse, deputy dean for enterprise and engagement at Aston University, said: “The programme has delivered a big social and economic impact with businesses ranging from hand-crafted paper goods to medical devices.” Carolyn Keenan, BSEEN project manager, said: “It has been a privilege to be involved with the programme from the beginning.” The eight awards presented during the event went to the following: BSEEN Rising Star Winner: Ruth Mestel and Charis McRoberts, Calathea Arts Highly Commended: Denise Amory-Reid, Amory R Management BSEEN Champion Award Winner: Ben Brophy, Ad Valorem Accountants Highly Commended: Richard Freeman and Jamie Partington, Higgs LLP Award for Technology Winner: Alliyah and Amirah Khan, Our Tied Camel Highly Commended: Safe Queen Team Award for Creative Industries Winner: Morgan Grice, Odd Orange Highly Commended: Andrea Craciun, Sweetest Mango Illustration Award for Innovation Winner: David Akraka, Akreon Technology Highly Commended: Hardeep Randhawa, ProLimbs Award for Social Impact Winner: Cleo Morris, Mission Diverse Highly Commended: Jamaal O’Driscoll, O’D Collective BSEEN Community Award Winner: Shovon Wiggan, Inspire-a-Doll Highly Commended: Janani Prasad, Supabite.com Award for Small Business Growth Winner: Bobby Bradstock, Serenity Psychotherapy Highly Commended: Joseph Housley and Connor Watt, Narce Media and Ben Curtis, Hobby Store Group. To find out more about the BSEEN programme, click here.
Potholes and Cracked Pavement Keep Barton Street East in the Top Spot on the provincial CAA Worst Roads List. The votes are in, and the CAA Worst Road for 2023 is Barton Street East in Hamilton. Barton Street's persistent issues with potholes and severe alligator cracking in the pavement have led to its dubious distinction. The road first appeared on the top 10 list in 2019 and has steadily climbed its way to the top now for the second year in a row. Taking the second and third place spots are roads that at one point have also crowned the top of the list, Eglinton Avenue West in Toronto and County Road 49 in Prince Edward County. "The 2023 CAA Worst Roads campaign provides a valuable snapshot of the roads that the public perceives as pain points," said Teresa Di Felice, assistant vice president for CAA South Central Ontario. "For 20 years, this campaign has served as a powerful advocacy tool, initiating dialogues with decision-makers and driving positive change for safer roads across Ontario." Four new roads have debuted this year on the provincial top 10 list. Laclie Street, Orillia, Steeles Avenue East, Toronto, Aberdeen Avenue, Hamilton and Hurontario Street, Mississauga. Many of the roads nominated have undergone or are undergoing significant improvements. The success stories of the campaign are primarily attributed to the government's prioritization of infrastructure through multi-year capital investments. These investments demonstrate the impact of proactive measures on enhancing road conditions and addressing public concerns. The CAA Worst Road list is verified this year by the Residential and Civil Construction Alliance of Ontario (RCCAO). “RCCAO is proud to support and partner with this year’s CAA Worst Roads advocacy campaign to give Ontarians a platform to raise awareness about the state of vital road infrastructure in their communities,” said Nadia Todorova, Executive Director of RCCAO. “The campaign highlights once again the need for dedicated funding to address the state-of-good-repair and maintenance of critical infrastructure needed to support our growing province. I want to thank RCCAO members for their initiative to offer their technical expertise to this campaign, including the Greater Toronto Sewer and Watermain Contractors Association (GTSWCA), Heavy Construction Association of Toronto (HCAT), and the Toronto and Area Road Builders Association (TARBA).” Ontario's Top 10 Worst Roads for 2023 Barton Street East, Hamilton Eglinton Avenue West, Toronto County Road 49, Prince Edward County Carling Avenue, Ottawa Finch Avenue West, Toronto Laclie Street, Orillia Steeles Avenue East, Toronto Aberdeen Avenue, Hamilton Lake Shore Boulevard East, Toronto Hurontario Street, Mississauga Worst Roads by Region Central— Laclie Street, Orillia Eastern— County Road 49, Prince Edward County Halton-Peel-York-Durham— Hurontario Street, Mississauga Niagara— Portage Road, Niagara Falls North— Algonquin Boulevard East, Timmins Southwest— Lauzon Parkway, Windsor Western— York Road, Guelph Ottawa— Carling Avenue, Ottawa For regional lists and historical results please visit: https://www.caasco.com/advocacy/worst-roads
Expert Insight: The Voice of Alexa: How Speech Characteristics Impact Consumer Decisions
In the 2020 film “Superintelligence,” an all-powerful artificial intelligence attempts to take over the world, and it studies an average person, played by Melissa McCarthy, to decide if humanity is worth saving. The AI is voiced by James Corden—a voice it chooses because it knows it’s one McCarthy’s character will engage with. Rajiv Garg, associate professor of Information Systems & Operations Management at Emory’s Goizueta Business School, shows the “Superintelligence” trailer before his research presentations to set the tone. Garg conducts research that explores the impact of artificial intelligence voices on consumer behavior and purchase intent, along with Haris Krijestorac, a professor at HEC Paris, and Vijay Mahajan, a professor from The University of Texas at Austin. Garg’s research began when Amazon launched celebrity voices for its Alexa device in 2019. From Samuel L. Jackson to Shaquille O’Neal, users can now get their news and entertainment, while interacting with their favorite superstars. “I questioned if certain voices could get more engagement or more purchases from consumers,” Garg says. If Alexa starts talking to you in Samuel L. Jackson’s voice, will you continue the conversation? What could Samuel L. Jackson’s voice sell you that you would buy? Garg and his team began their research by collecting more than 300 celebrity voice samples, which they analyzed based on their sound characteristics, such as amplitude, frequency, and entropy. They looked at 20 sound characteristics and identified that all the voices could be segmented into six clusters: ostentatious, colloquial, friendly, authoritative, seductive, and suave. The team then created advertisements for select products using computer generated voices for each of the six clusters, opting for artificial intelligence-created speech instead of celebrity deep fakes due to permission legalities. They chose a shoe and an office chair as their products, and created two different advertisements for each product. One ad was simple, denoting the shoe as comfortable for all-day wear and the office chair as comfortable for sitting in for extended time periods. The other ad was hedonic, denoting the shoe as crafted with Italian leather and the office chair equipped with several massage features. They recorded the four advertisements using both a female and male voice for all six voice clusters. Study participants listened to each of the four advertisements in one of the 12 voices, which was randomly selected. After the advertisement was played, participants were asked if they wanted more information, and later, if they wanted to buy the product (omitting the price as to not add another factor to their decision making). Influencing Consumer Behavior For simple, utilitarian products, they found no significant effect of voice on information seeking behavior. Garg says once participants hear this type of advertisement, they simply decide to purchase or move on. Participants do, however, engage more in information seeking behavior for hedonic products when the voice is ostentatious, seductive, or authoritative. The team also found men were more likely than women to engage with ostentatious or seductive voices, and women were more likely to engage with friendly or colloquial voices. Overall, they found participants did not seek information with male voices. For information seeking, men and women only engage if the voices are female, which is somewhat intuitive. The industry is doing this—Alexa, Google, and Siri all have a female voice. In terms of purchase intention, they found ostentatious voices have higher yields for utilitarian products. Men, especially, were more likely than women to purchase a utilitarian product advertised in an ostentatious voice. Think about advertising a stapler. It’s a stapler—it staples paper—but you advertise it in a French accent to make it sound interesting. Conversely, for hedonic products, an ostentatious voice has a negative effect on purchase intent because Garg says it can make the product sound gimmicky. Their research shows colloquial voices do the best here because people focus more on the advertisement’s content. Across the board, they found seductive voices have a negative effect on purchase intent, but more so on utilitarian products compared to hedonic ones. Men were more likely than women to respond positively to seductive and suave voices. Applying the results Voices are another way smart device companies can personalize their customers’ experiences. Garg says these companies should be aware that there may be a certain voice that will garner the best engagement. Their findings are not isolated to business, but may apply to other industries, such as the media. Garg says, for example, if publications intend to increase reader curiosity and engagement, they should use a female colloquial voice on “click to listen” features. Although not yet tested, Garg says he wouldn’t be surprised if their results extend to real-world settings with real human voices as well. During their research, Garg’s team asked participants if they had heard the advertisement voices before, and about 15 percent of respondents says they had. "These were voices we’d created for the first time,” Garg says. “If they say they’ve heard the voice before, that means they were thinking of them as human voices. Although we didn’t study it that way, I do believe what we’re seeing will be relevant for actual human being’s voices and interactions.” Having researched this for years, Garg says every time he listens to a voice, whether a customer service representative or podcast host, he questions whether or not it is impacting his behavior. A lot of times when I’m making a decision, I know that I’m making that decision passively because of the voice. “I’m acting 50 percent based on the rational information in the voice, but the other 50 percent I just want to listen more. There is an inherent desire for a certain voice.” Garg says his favorite part of the research are those “aha moments,” whether they be the influence of voice in his own life or in the industry—such as large companies using female voices in their products to draw engagement. He says he hopes to continue doing this kind of research to help startups and other companies perform better, as AI-powered voices continue to change the way people interact with technology and consume information. “We’re finding these interesting phenomena that can help create new products that are more effective,” Garg says. “I am trying to increase the economic surplus, in some ways to improve society, and this technology presents numerous opportunities.” Looking to know more? Rajiv Garg from Emory’s Goizueta Business School is available to speak with media – simply click on his icon now to arrange an interview today.
Aston University biofuel experts advise on how Ukraine can build back greener
• Aston University biofuel experts provide advice on Ukraine’s recovery • Professor Patricia Thornley and Dr Vesna Najdanovic were invited to Royal Society conference • Outcomes will be presented to policymakers at Ukraine Recovery Conference in June. Two Aston University scientists have provided expert advice on how the UK’s wealth of research can support Ukraine’s reconstruction. A two-day conference was organised by the Royal Society and its outcomes will be presented to policymakers ahead of the UK government-hosted Ukraine Recovery Conference in June. As Ukraine is one of the largest agricultural producers and exporters it also generates large amounts of agricultural waste which could be used to produce biofuels and valuable chemicals. This could decrease the country’s fuel import dependency and increase the revenues for the sector. Researchers at the conference explored how to tackle some of the many challenges facing Ukraine, from rebuilding its economy, health and wellbeing, regional security and planning for a green recovery. Professor Patricia Thornley who is director of Aston University’s Energy and Bioproducts Research Institute (EBRI), was one of the just three academics invited to contribute to an infrastructure roundtable session. Professor Thornley said: “I was honoured to be asked to attend the infrastructure roundtable and share my expertise on renewable energy and sustainable products. “Ukraine has significant sustainable agricultural and forestry residues, which can be valuable to plug potential gaps in oil and gas supply for heating in the short term. But in the long term these can provide opportunities to produce sustainable bio chemicals and materials which could provide a basis to grow green chemical, material and construction industries. “UK researchers, such as those at EBRI at Aston University and the Supergen Bioenergy Hub, have the experience needed to work on developing these solutions to build back greener. Research evidence and expertise have a vital role to play in supporting policy makers to tackle the complex and urgent challenges related to the reconstruction and recovery of a resilient, sustainable Ukraine.” Meanwhile, Dr Vesna Najdanovic presented opportunities to develop bioenergy and bioproducts in Ukraine at the event and participated as a panel member. Ukraine’s recovery: rebuilding with research, which brought together Ukrainian and UK researchers and policy makers, was held on 15 and 16 May in London. It was funded by Universities UK International, Research England and the British Council and supported by the Academy of Medical Sciences, British Academy and the Royal Academy of Engineering.
Amanda Hewes, MS, education program manager at ChristianaCare’s Gene Editing Institute, has been named one of the 2023 Outstanding Delaware Women in STEM by Million Women Mentors, an international movement dedicated to encouraging girls and women to pursue careers in science, technology, engineering and math (STEM). Hewes’ selection spotlights her dedication to engaging young people in the science of gene editing by introducing the Gene Editing Institute’s CRISPR in a BoxTM educational toolkit into classrooms across Delaware and her commitment to bridging disparities in STEM education. “I’m overjoyed to be honored among so many amazing women in this state,” Hewes said. “It’s humbling to be considered and to stand alongside them. All of these women foster and lead dynamic communities of young women that inspire me every day. I hope that I can do the same by making young women in this state feel empowered through the work that I do.” Hewes joined ChristianaCare’s Gene Editing Institute in 2017 with a focus on expanding its CRISPR gene editing system in a cell-free environment. She was first author in a publication in Nature that established the highly innovative “gene editing on a chip” protocol that allowed CRISPR to edit DNA outside of the cell for the first time. This methodology enables researchers to take fragments of DNA extracted from human cells, place them in a test tube and precisely engineer multiple changes to the genetic code. This gene editing system eventually led to the creation of the CRISPR in a Box™ toolkit. This innovative educational resource provides a way for students to learn about this exciting frontier of science through a hands-on exercise in which they use CRISPR gene editing to disrupt a synthetic gene within a plasmid. The simplicity of this experiment allowed for the reaction to be developed into a remarkable teaching tool that can be brought into most school laboratories containing basic laboratory equipment. Once CRISPR in a Box™ was developed, Hewes recognized the potential it could have for high school and college students. She took on a new role as education program manager and expanded the Gene Editing 360™ platform, which is the Gene Editing Institute’s suite of educational tools for engaging students and the public. “Amanda has set us on a tremendous path toward providing more educational opportunities for Delaware students,” said Eric Kmiec, Ph.D., director of ChristianaCare’s Gene Editing Institute. “She’s inspired young women in multiple states and has created so much of this program with her own ingenuity and passion.” Hewes was honored alongside 10 other women by Gov. John Carney, Lt. Gov. Bethany Hall-Long and others at the Delaware State House with the signing of a proclamation to declare March 24, 2023, as “Delaware Women and Girls in STEM Day.”
A new book, A Student’s Guide to Open Science: Using the Replication Crisis to Reform Psychology, has been published, providing students and researchers with a comprehensive guide to open science practices and how their implementation can enhance research transparency and rigour. In the book, Dr Charlotte Pennington who is a lecturer in psychology at Aston University, explores the "replication crisis" in psychology, which refers to the difficulties in reproducing research results to test the robustness of findings. Through the book, students will gain an understanding of the origins and drivers of the crisis and learn how open science practices can transform research practice, enhance research transparency, and improve replication and reproducibility. The book contains various features, including an overview of landmark events that will mark the history of the replication crisis in the years to come, case studies of classic psychological studies undergoing replication, ‘test yourself’ activities to reinforce learning of key concepts, and top tips for adopting open science practices. It also includes useful illustrations to aid understanding and facilitate revision. Dr Pennington said: "The replication crisis has highlighted significant issues in the field of psychology and beyond and has led to a lack of trust in some research findings. However, it also provides a platform for reform – to improve research practices and the wider culture, with the discipline of psychology paving the way. I am proud that there is now a textbox that provides students and researchers with a handy guide on how to improve transparency and rigor in research through open science practices. “It is essential for all students to have a fundamental understanding of the challenges posed by the replication crisis and how open science can address them." The book has received high praise from experts in the field. Professor Chris Chambers from Cardiff University said: "This book should be on the reading list for all university science degrees and on all library bookshelves. It is concise, accessible, and remarkably interactive, with brilliant use of examples and learning activities.” Dr Madeleine Pownall from the University of Leeds said: "It is essential reading for anyone who wants to make sense of open science, by covering complex content in an accessible and hands-on way. My hope is that every psychology student will finish their degree with a heavily annotated, well-thumbed copy of this important and timely book.” Professor Brian Nosek, executive director of the Centre for Open Science at the University of Virginia said: “The last 10 years have been a whirlwind in psychology: identification of faulty research practices, frequent failures to replicate findings, research on how the field could improve, and adoption of new solutions to make research more transparent and credible. It is a lot to take in and it is hard to know where to start. “I am frequently asked to recommend a reading that provides an overview of what has been learned during the last 10 years and a gateway for getting started with open science. With this book, now I have an answer.” A Student’s Guide to Open Science: Using the Replication Crisis to Reform Psychology is now available in print and online formats.
Aston University celebrates becoming a University of Sanctuary with official event
Aston University officially celebrated becoming a University of Sanctuary with an event held on 16 May for all those who contributed to achieving this status. The University was awarded University of Sanctuary status in December 2022, joining a network of higher education institutions across the UK working to develop support for those displaced by humanitarian crises. The celebration was hosted by Aston University Vice-Chancellor and Chief Executive, Professor Aleks Subic. Guests included Councillor John Cotton, Birmingham City Council Cabinet member for Social Justice, Community Safety and Equalities, who made a special award presentation. The event programme also included a performance by poet Loraine Masiya Mponela, who herself was an asylum seeker and conversations with recipients of Ernest Edward Scholarships, a sanctuary scholarship scheme for students who have sought refuge in the UK. The scheme was set up by Aston University in 2022 due to a generous donation by prominent businessperson Matthew Crummack. Universities of Sanctuary is an initiative to recognise and celebrate the good practice of institutions welcoming people seeking sanctuary through facilitated access to higher education, supporting local refugee communities and taking an active role in learning about the issues and obstacles faced by this group in pursuing university-level education. Professor Aleks Subic, Vice-Chancellor and Chief Executive of Aston University, said: “I am delighted to have had this opportunity to host a celebration event to thank everyone who has helped us achieve the University of Sanctuary status. “Aston University is committed to supporting people seeking sanctuary through its efforts to deepen our understanding of the issues surrounding asylum seekers and refugees, providing a welcoming environment for sanctuary students, and working with individuals and communities beyond the campus to promote the values and principles of sanctuary. “Being a University of Sanctuary is key to our Civic Agreement: our commitment to make Birmingham a better place for everyone who lives, works, and studies here. Birmingham." Councillor John Cotton, Birmingham City Council Cabinet member for Social Justice, Community Safety and Equalities, said: “Birmingham is proud to be a City of Sanctuary, with its long history of offering refuge to those fleeing war, persecution and tyranny around the globe. In these troubled times, standing up for the principles of sanctuary and refuge is more important than ever. “I’m delighted that Aston University has joined the family of Universities of Sanctuary and is one of the many important institutions in our city that actively extends the hand of friendship to those seeking refuge and the chance to rebuild their lives here in Birmingham.”
Ana Palacios’ interview on “Eagle Eye View,” the official podcast of Georgia Southern University. Palacios discusses her research and how being a mom motivated her. Several esteemed nutrition researchers collaborated on “Effectiveness of Lactation Cookies on Human Milk Production Rates: A Randomized Controlled Trial,” which was recently published in The American Journal of Clinical Nutrition. David B. Allison, Ph.D., dean of the Indiana University School of Public Health-Bloomington (SPH-B), is among the researchers who conducted a one-month, randomized controlled trial of lactating parents of healthy babies in the same age range. Their findings revealed no evidence for an effect of consuming lactation cookies on human milk production. “Too often in the field of nutrition and food, strong beliefs—sometimes even well-reasoned conjectures based upon some scientific knowledge—are mistaken for demonstrated facts,” Allison said. “Conjecture is good, but knowing is better. We come to know about the effects of nutrition and dietary supplements through rigorous, randomized, controlled trials. Having conducted such a study on lactation cookies, we found no evidence for their effectiveness. “This does not mean that it is impossible for any lactation cookie to affect human milk production,” he continued. “This study does suggest that the cookies we studied—under the conditions we studied them—have no discernible effect. The burden of proof seems to now be on those who claim there is an effect.” The study followed 176 U.S. parents who were exclusively breastfeeding healthy two-month-old babies. One group of parents was provided a serving of commercially available lactation cookies to consume daily for a month; the other group of parents ate a serving of conventional cookies not designed to increase lactation, each day for a month. Through a weekly survey, parents reported the quantity of milk they produced after following a validated milk expression protocol using a hospital-grade breast pump, providing data that were analyzed by both the study authors and an independent statistician. These data demonstrated that the impact of consuming lactation cookies did not have a significant effect on how much milk was actually produced or perceived to be produced by the lactating parents. The authors assert that consumers should be cautious when considering the potential effect of this product, or any food and/or supplement that promotes health-promoting benefits without published, peer-reviewed scientific evidence to support its claims. As the researchers noted, these lactation cookies can contain substantial calories and sugars, which could affect postpartum weight loss efforts and related health issues. “Despite being a physician and nutrition scientist focused on early-life nutrition, I still remember how difficult breastfeeding was for me with both of my children,” said study lead author Ana M. Palacios, MD, Ph.D., assistant professor, Department of Health Policy and Community Health, Jiann-Ping Hsu College of Public Health at Georgia Southern University. “Our research highlights that lactation cookies, which include added sugars and saturated fat, may not have the said purported benefits of increasing milk production. Purchasing lactation cookies to increase milk production may pose an unnecessary cost and may have additional implications for parents, such as limiting post-pregnancy weight loss and reducing consumption of healthier foods. More research is needed to better understand what foods and nutrients can best help increase milk supply in diverse populations.” The full article, along with the list of contributing authors, is available by simply clicking the article below: Interested in learning more? For more information about this research or to speak with Ana M. Palacios — simply reach out to Georgia Southern's Director of Communications Jennifer Wise at jwise@georgiasouthern.edu to arrange an interview today.
Aston University wins grant to make research more sustainable and environmentally friendly
University awarded grant to develop more sustainable separation method through AstraZeneca’s Open Innovation CoSolve Challenge at ELRIG Dr Vesna Najdanovic will explore use of the solvent ethyl lactate It is a biorenewable and environmentally friendly alternative. An Aston University scientist has won a $25000 grant in the AstraZeneca Open Innovation CoSolve sustainability challenge to help to make research more sustainable and environmentally friendly. Dr Vesna Najdanovic, senior lecturer in chemical engineering at the University’s Energy and Bioproducts Research Institute (EBRI), successfully pitched her idea to explore a new method using ethyl lactate as a solvent. Ethyl lactate is a biorenewable and environmentally friendly alternative solvent produced from lactic acid and ethanol, both obtained by fermentation of biomass. Currently hazardous organic solvents such as acetonitrile are widely used instead. Dr Najdanovic won the AstraZeneca’s Open Innovation CoSolve Sustainability Challenge at the European laboratory research & innovation group (ELRIG) Research and Innovation meeting. She said: “Throughout my research career, I have been working with various green solvents, such as supercritical fluids, ionic liquids and biosolvents, to improve chemical and separation processes. “I am delighted to be selected by the expert judging panel and the highly engaged audience to apply my knowledge to develop greener analytical methods using ethyl lactate as a solvent for liquid chromatography. “I hope this project will pave the pathway to use this environmentally friendly alternative solvent while reducing carbon footprint and pollution”. The pharmaceutical industry generates the highest amount of waste per mass of products compared to other chemical industry sectors, such as the petroleum industry, bulk and fine chemicals. Dr Kelly Gray, CoSolve sustainability programme lead at AstraZeneca, said “In order to protect people, society and planet we have to identify and develop solutions to deliver sustainable science. The goal of the CoSolve sustainability programme was to do just that and identify innovative ideas to practical challenges faced by researchers across scientific disciplines in R&D.” Sanj Kumar, CEO of ELRIG, said “Ensuring that drug discovery processes become sustainable is a priority issue to the ELRIG community, so partnering with AstraZeneca on the CoSolve initiative, by hosting the pitching and final award ceremony, is not only an honour, but raises the awareness of sustainability to our community. Dr Najdanovic and her innovation are a worthy winner and ELRIG is proud that we are able to share her success story.” As much as 80% of this waste presents hazardous organic solvents obtained from petrochemical sources. For example, the pharmaceutical industry consumes 50% of globally produced acetonitrile, of which 20% is a solvent for liquid chromatography, a widely used analytical tool in research and development laboratories. After its use, most acetonitrile is discarded as chemical waste and subsequently incinerated, generating greenhouse gases and other pollutants such as nitrogen oxides and highly toxic hydrogen cyanide. The CoSolve sustainability challenge award builds on Dr Najdanovic’s previous work employing ethyl lactate as a solvent for various separation processes. Her new project supports EBRI’s wider objectives of using bioproducts to deliver low-carbon and environmentally sustainable solutions.
Gene Editing Institute Opens a Unique Learning Lab for High School and College Students
Free program uses CRISPR in a Box™ toolkit to teach the power of gene editing To inspire the next generation of students to pursue careers in STEM (science, technology, engineering and math) and learn about the power of genomic science, ChristianaCare’s Gene Editing Institute has launched a new Learning Lab on its premises that offers educational programming about revolutionary CRISPR gene editing technology. Located next to the Gene Editing Institute’s lab on the University of Delaware’s STAR Campus, the Learning Lab is a physical space that provides an immersive field trip experience for upper-level high school students and college undergraduates who may not have access at their schools to a laboratory to conduct gene editing experiments. There is no cost for schools to use the lab or for the materials to conduct the experiment. The Gene Editing Institute wants to ensure that all schools have equal opportunity to participate in educational programming at the lab. Students using the lab can perform a gene editing experiment in a single day using the Gene Editing Institute’s innovative CRISPR in a Box™ educational toolkit. All materials in the kit are safe, synthetic materials, and allow students to perform CRISPR gene editing with non-infectious E. coli bacteria. They will be able to see an appearance change indicating gene editing has occurred at the end of their experiment. “Students around the country, no matter where they go to school, have the potential to be scientists, researchers and laboratory technicians,” said Eric Kmiec, Ph.D., executive director and chief scientific officer of ChristianaCare’s Gene Editing Institute. “Our hope is that by creating access and space for students to explore, we can inspire the next generation of students to pursue STEM careers. The Learning Lab allows us to help cultivate the next generation of genetic scientists and strengthen Delaware and our region as a leader in biotechnology.” Education Program Manager Amanda Hewes, MS, developed the Learning Lab after noticing a problem that was undercutting the opportunities of teachers to bring gene editing experiments into the classroom — a lack of space and equipment. Amanda Hewes, education program coordinator, assists students from Wilmington Charter School with their samples of DNA during a Learning Lab experiment. “We don’t want anything to hinder the way students learn about CRISPR gene editing,” Hewes said. “If a student feels like there are too many steps, or a teacher doesn’t have an essential piece of equipment, then we’ve lost an opportunity to bring the next generation of scientists into the lab. We’re striving to break down as many barriers as possible for students.” Learning real-world applications of gene editing The Learning Lab also allows students to speak directly with experts in the field about careers in biotechnology and gene editing as they learn the difference between such things as phenotypic and genotypic readouts in their gene editing experiments. This gives students the chance to ask about the real-world application of genome experiments in a research lab. It also lets them think about their place in a lab setting. “I’ve never been in an actual lab setting before,” said Shiloh Lee, a junior at the Charter School of Wilmington, at a recent class. “I think it is very, very cool to be able to experience it.” “I’ve learned a lot of new skills with the micropipetting,” said Pauline Zhuang, a senior at The Charter School of Wilmington. “We don’t have the same resources at our school. The CRISPR in a Box is such a great resource. My classmates and I have been able to experience, firsthand, what it is like to actually do gene editing.” Through the program, the Gene Editing Institute hopes to educate 1,000 students by spring 2024. Currently, the lab is on track to engage more than 200 students by the end of the spring 2023 semester. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas 9 genome editing technology. The CRISPR technology enables researchers to modify genes in living cells and organisms and may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease. For more information about the Learning Lab and the educational program, email geneeditinginstitute@christianacare.org.
