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The new device is designed to reduce the risk of injuries when medicines being delivered into a vein enter the surrounding tissues It detects this problem at the earliest stages, before it is visible to the human eye The project is being supported by SPARK The Midlands at Aston University, a network to support technology development for unmet clinical needs. Clinicians at Birmingham Women’s and Children's NHS Foundation Trust (BWC) have joined with academics at Aston University to create an innovative sensor to reduce the risk of injuries caused when drugs being delivered into a vein enter the surrounding tissue. This complication, called extravasation, can cause harm and, in the most severe cases, life-changing injuries and permanent scarring. It happens most often when infusing medicines into peripheral intravenous (IV) devices, such as a cannula, but can also occur when infusing into a central venous access device. By joining together, BWC and Aston University are combining clinical, academic and engineering expertise to create a sensor that can detect extravasation at its earliest stages. Karl Emms, lead nurse for patient safety at BWC, said: “We've done lots of work across our Trust that has successfully reduced incidents. While we've made fantastic progress, there is only so much we can do as early signs of extravasation can be difficult to detect with the human eye. “The next step is to develop a technology that can do what people can't - detection as it happens. This will make a huge impact on outcomes as the faster we can detect extravasation, the less likely it is that it will cause serious harm.” The focused work to date addressing the issue has recently been recognised by the Nursing Times Awards 2024, winning the Patient Safety Improvement title for this year. This new project is supported by SPARK The Midlands, a network at Aston University dedicated to providing academic support to advance healthcare research discoveries in the region. SPARK The Midlands is the first UK branch of Stanford University's prestigious global SPARK programme. It comes as a result of Aston University’s active involvement in the delivery of the West Midlands Health Tech Innovation Accelerator (WMHTIA) – a government-funded project aimed at helping companies drive their innovations towards market success. The SPARK scheme helps to provide mentorship and forge networks between researchers, those with technical and specialist knowledge and potential sources of funding. SPARK members have access to workshops led by industry experts, covering topics such as medical device regulations, establishing good clinical trials, and creating an enticing target product profile to engage future funders. Luke Southan, head of research commercialisation at Aston University and SPARK UK director, said: “I was blown away when Karl first brought this idea to me. I knew we had to do everything we could to make this a reality. This project has the potential to transform the standard of care for a genuine clinical need, which is what SPARK is all about.” Work on another potentially transformative project has also begun as the team are working to develop a medical device that detects the position of a nasogastric feeding tube. There is a risk of serious harm and danger to life if nasogastric tubes move into the lungs, rather than the stomach, and feed is passed through them. Emms explained: “pH test strips can usually detect nasogastric tube misplacement, but some children undergoing treatment can have altered pH levels in the stomach. This means this test sometimes does not work. “A medical device that can detect misplacement can potentially stop harm and fatalities caused by these incidents.” SPARK will bring together engineers, academics and clinicians for both projects to develop the devices for clinical trial, with a goal of the technologies being ready for clinical use in three to five years. Southan said: “BWC is one of our first partners at SPARK and we're really excited to work with them to make a vital impact on paediatric healthcare in the Midlands and beyond." Notes to editors About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming the Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Helen Tunnicliffe, Press and Communications Manager, on (+44) 7827 090240 or email: h.tunnicliffe@aston.ac.uk About Birmingham Women’s and Children’s NHS Foundation Trust Birmingham Women’s and Children’s NHS Foundation Trust (BWC) brings together the very best in paediatric and women’s care in the region and is proud to have many UK and world-leading surgeons, doctors, nurses, midwives and other allied healthcare professionals on its team. Birmingham Children’s Hospital is the UK’s leading specialist paediatric centre, caring for sick children and young people between 0 and 16 years of age. Based in the heart of Birmingham city centre, the hospital is a world leader in some of the most advanced treatments, complex surgical procedures and cutting-edge research and development. It is a nationally designated specialist centre for epilepsy surgery and also boasts a paediatric major trauma centre for the West Midlands, a national liver and small bowel transplant centre and a centre of excellence for complex heart conditions, the treatment of burns, cancer and liver and kidney disease. The hospital is also home to one of the largest Child and Adolescent Mental Health Services in the country, comprising of a dedicated inpatient Eating Disorder Unit and Acute Assessment Unit for regional referrals of children and young people with the most serious of problems (Tier 4) and Forward Thinking Birmingham community mental health service for 0- to 25-year-olds. Birmingham Women’s Hospital is a centre of excellence, providing a range of specialist health care services to over 50,000 women and their families every year from Birmingham, the West Midlands and beyond. As well as delivering more than 8,200 babies a year, it offers a full range of gynaecological, maternity and neonatal care, as well as a comprehensive genetics service, which serves men and women. Its Fertility Centre is one of the best in the country, while the fetal medicine centre receives regional and national referrals. The hospital is also an international centre for education, research and development with a research budget of over £3 million per year. It also hosts the national miscarriage research centre – the first of its kind in the UK - in partnership with Tommy’s baby charity. For interview requests please email the Communications Team on bwc.communications@nhs.net
Kert Anzilotti, M.D., Appointed President of the Medical Group of ChristianaCare
Kert Anzilotti, M.D., MBA, FACR has been appointed president of the Medical Group of ChristianaCare. Anzilotti has served as interim president since June 2024. He will also continue in his role as system chief medical officer of ChristianaCare. As president of the ChristianaCare Medical Group, Anzilotti will seek to improve every aspect of care for every person the Medical Group touches. He will focus on the optimization of care delivery, strategic visioning, network development, clinical technology implementation and leveraging medical informatics. Anzilotti will continue to develop new care models that transcend settings, promote value-based care and improve the patient experience across the clinical enterprise. Among his priorities are the adoption of population health measures, the embedding of health equity into care delivery and workforce development, further expansion of access points for patients and the continuous enhancement of patient and caregiver experience. “Dr. Anzilotti is exceptionally qualified to lead the Medical Group of ChristianaCare,” said Janice E. Nevin, M.D., MPH, president and CEO of ChristianaCare. “His passion for our mission and vision for the future strength of our Medical Group is unwavering. Since joining ChristianaCare in 2011, Dr. Anzilotti has earned a well-deserved reputation as a thoughtful and collaborative leader.” Anzilotti has served in numerous leadership roles at ChristianaCare, including as chief medical officer, acute care; chair of the Department of Radiology; medical director of Imaging Services; and physician leader of the Neurosciences Service Line. He also previously served as Interim President and CEO for the eBrightHealth ACO with responsibility for physician leadership and network operations. He is board certified in Neuroradiology. “Over the many years I have been at ChristianaCare, I have had the privilege of witnessing the dedication and compassion of my Medical Group colleagues as we served together with love and excellence,” Anzilotti said. “I am honored to lead this incredible, dynamic group that is reshaping the future of care, ensuring everyone we serve can achieve their best health.” Anzilotti earned his medical degree from Jefferson Medical College of Thomas Jefferson University in Philadelphia. He earned his MBA at the University of Delaware, completed the Managing Health Care Delivery Course at Harvard Business School and graduated as Physician Executive Fellow in the Health Management Academy, GE Fellows Program. The Medical Group of ChristianaCare consists of over 2,200 dedicated doctors, nurse practitioners, physician assistants and other caregivers. This highly skilled team delivers exceptional care through ChristianaCare’s community-based primary care and specialty care practices serving Delaware and surrounding states. Additionally, the Medical Group collaborates with ChristianaCare hospitalists to ensure seamless continuity of care for our patients, from primary care to hospital care and back again.
New light technique could revolutionise non-invasive medical diagnostics Orbital Angular Momentum could be harnessed to improve imaging and data transmission through biological tissues Could eventually have potential to make procedures such as surgery or biopsies unnecessary. An Aston University researcher has developed a new technique using light which could revolutionise non-invasive medical diagnostics and optical communication. The research showcases how a type of light called the Orbital Angular Momentum (OAM) can be harnessed to improve imaging and data transmission through skin and other biological tissues. A team led by Professor Igor Meglinski found that OAM light has unmatched sensitivity and accuracy that could result in making procedures such as surgery or biopsies unnecessary. In addition it could enable doctors to track the progression of diseases and plan appropriate treatment options. OAM is defined as a type of structured light beams, which are light fields which have a tailored spatial structure. Often referred to as vortex beams, they have previously been applied to a number of developments in different applications including astronomy, microscopy, imaging, metrology, sensing, and optical communications. Professor Meglinski in collaboration with researchers from the University of Oulu, Finland conducted the research which is detailed in the paper “Phase preservation of orbital angular momentum of light in multiple scattering environment” which is published in the Nature journal Light Science & Application. The paper has since been named as one of the year’s most exciting pieces of research by international optics and photonics membership organisation, Optica. The study reveals that OAM retains its phase characteristics even when passing through highly scattering media, unlike regular light signals. This means it can detect extremely small changes with an accuracy of up to 0.000001 on the refractive index, far surpassing the capabilities of many current diagnostic technologies. Professor Meglinski who is based at Aston Institute of Photonic Technologies said: “By showing that OAM light can travel through turbid or cloudy and scattering media, the study opens up new possibilities for advanced biomedical applications. “For example, this technology could lead to more accurate and non-invasive ways to monitor blood glucose levels, providing an easier and less painful method for people with diabetes.” The research team conducted a series of controlled experiments, transmitting OAM beams through media with varying levels of turbidity and refractive indices. They used advanced detection techniques, including interferometry and digital holography, to capture and analyse the light's behaviour. They found that the consistency between experimental results and theoretical models highlighted the ability of the OAM-based approach. The researchers believe that their study’s findings pave the way for a range of transformative applications. By adjusting the initial phase of OAM light, they believe that revolutionary advancements in fields such as secure optical communication systems and advanced biomedical imaging will be possible in the future. Professor Meglinski added: "The potential for precise, non-invasive transcutaneous glucose monitoring represents a significant leap forward in medical diagnostics. “My team’s methodological framework and experimental validations provide a comprehensive understanding of how OAM light interacts with complex scattering environments, reinforcing its potential as a versatile technology for future optical sensing and imaging challenges.” ENDS https://www.nature.com/articles/s41377-024-01562-7 Light: Science & Applications volume 13, Article number: 214 (2024) August 2024 https://doi.org/10.1038/s41377-024-01562-7 Authors: Igor Meglinski, Ivan Lopushenko, Anton Sdobnov & Alexander Bykov About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Money vs Memories in Retirement
Summary: This article explores whether or not money or memories will bring more comfort to the elderly. It is written with the underlying assumption that there is already enough money to meet basic living expenses. As we age, the question of what will bring us the most comfort in our twilight years becomes increasingly relevant. For many, it comes down to two key aspects: money and memories. On the one hand, financial security provides a foundation of comfort, ensuring that one’s needs are met without the fear of lacking resources. On the other hand, cherished memories bring emotional warmth, helping individuals navigate the often-challenging aging journey. In this article, we will explore which of these two — money or memories—plays a more significant role in delivering comfort in old age, assuming one has enough financial resources to cover basic living expenses. While I appreciate that good health takes precedence over money and memories, we unfortunately do not have complete control over our health. However, we have control over our decision to save our money to give us comfort. Or we can choose to spend our money to create memories that will provide us with comfort. Financial Security: A Foundation for Comfort Money is a powerful enabler, allowing us to meet our needs and desires. It's particularly important in the context of aging because it can mitigate many of the hardships of growing older. 1. Access to Quality Healthcare: One of the most significant concerns for elderly individuals is health. With aging comes a higher likelihood of chronic conditions, disabilities, and the need for regular medical attention. Financial security allows individuals to afford quality healthcare, access advanced treatments, and have the freedom to choose the best facilities. Having sufficient money provides a critical safety net for those who experience sudden medical emergencies or need long-term care. 2. Comfortable Living Arrangements: As people age, they often face the decision of where to live. While some prefer to stay home, others may move to assisted living facilities or hire caregivers. Financial resources enable elderly individuals to choose comfortable living environments tailored to their needs and preferences. A well-maintained home, access to mobility aids, or a peaceful retirement community can significantly enhance an individual’s day-to-day life. 3. Freedom and Autonomy: Financial independence in old age allows for greater autonomy. With money, elderly individuals can control their lives by making choices that suit their preferences, such as travelling, pursuing hobbies, or supporting loved ones. The ability to make decisions about healthcare, leisure, or everyday living preserves dignity and independence, both of which are central to feeling comfortable and fulfilled. 4. Reducing Stress and Anxiety: Aging can bring about several uncertainties, especially health and mobility. However, financial security can significantly reduce the stress and anxiety of worrying about the future. Knowing that expenses, including potentially unforeseen ones, are covered allows elderly individuals to focus on enjoying life rather than constantly fretting over how to afford their basic needs. This peace of mind is invaluable in ensuring a comfortable old age. While money plays a crucial role in creating a foundation of comfort, it has emotional and psychological well-being limitations. This is where memories come into play. Memories: Emotional Anchors in the Journey of Aging As the years pass, memories become a primary source of emotional sustenance. They connect individuals to their past, their loved ones, and the experiences that shaped their lives. When people reflect on what matters most to them in old age, it’s often not material wealth but the moments that brought them joy, love, and meaning. 1. Emotional Fulfillment: Memories of joyful experiences, adventures, and time spent with loved ones can offer deep emotional fulfillment in old age. Recalling meaningful moments provides a sense of accomplishment and satisfaction, reminding individuals of the richness of their lives. For many, the bonds formed with family and friends, the challenges overcome, and the dreams pursued give life meaning and offer comfort in later years. 2. Connection to Loved Ones: As elderly individuals have fewer physical responsibilities, they often spend more time reminiscing. Positive memories help bridge the gap between generations, allowing the elderly to connect with their children, grandchildren, and even great-grandchildren. Sharing stories from the past strengthens family bonds and ensures that their legacy lives on, creating a sense of continuity and significance. 3. Combatting Loneliness: People may experience increased isolation as they age, particularly after losing a spouse or friends. In such times, memories serve as a balm for loneliness. Even in moments of solitude, recalling past experiences, adventures, or time spent with loved ones can bring comfort. Memories provide companionship in their own right, filling the gaps left by physical absence and reducing feelings of loneliness. 4. Identity and Self-Continuity: Our memories are integral to our identity. They help us understand who we are by reminding us of the paths we've taken, the challenges we’ve faced, and the triumphs we’ve celebrated. For elderly individuals, the ability to look back on a life well-lived reinforces their sense of self. Memories act as an anchor, helping them feel grounded as they navigate the changes that come with aging. 5. Psychological Resilience: Life is inevitably full of hardships, and old age is no exception. However, memories of overcoming past difficulties provide emotional strength and resilience. Looking back on moments of hardship reminds elderly individuals that they’ve faced challenges before and emerged stronger. This sense of resilience can be empowering in the face of the physical and emotional challenges of aging. Balancing Money and Memories It’s essential to recognize that money and memories are not mutually exclusive; they often complement each other. While financial security provides the external comfort and security needed to navigate old age, memories provide the internal warmth and emotional fulfillment that give life depth and meaning. In determining which offers more comfort, it’s essential to consider an underlying assumption: there is already enough money to meet basic living expenses. In this scenario, it becomes clear that while financial resources are essential, memories are more significant. Consider the following: 1. Life Experiences Are Often Enabled by Money: The ability to create cherished memories often depends on financial resources. Travelling, pursuing hobbies, and spending quality time with loved ones may all require money. However, the memories created from these experiences—not the money spent—bring lasting comfort. In old age, the satisfaction of having lived a rich life full of meaningful experiences often outweighs the material possessions acquired. 2. Financial Security Loses Meaning Without Emotional Fulfillment: Imagine having all the money needed in old age but lacking meaningful memories or connections to loved ones. In this case, wealth would bring only a hollow sense of comfort. With emotional fulfillment, money is likely to provide lasting satisfaction. In contrast, those with a lifetime of cherished memories may find comfort even in modest circumstances, as their inner wealth—their experiences—remains invaluable. 3. The Longevity of Memories vs. Material Wealth: As we age, our ability to enjoy material goods and external pleasures may diminish due to declining health or physical limitations. However, memories transcend physical limitations. Even if elderly individuals cannot travel or engage in once-loved activities, they can still find joy in recalling their past. In this sense, memories have a longevity that material wealth may lack. 4. Regret and Fulfillment in Old Age: Many studies have shown that people regret missed opportunities and unfulfilled relationships far more than financial shortcomings at the end of life. The things that bring peace and comfort in old age are often intangible: love, connection, purpose, and meaning. Memories of having lived a full life, having nurtured relationships, and having followed one’s passions often bring a greater sense of contentment than wealth alone. The Enduring Power of Memories In the context of aging, both money and memories play significant roles in creating comfort. Financial security provides the practical means to ensure health, independence, and a comfortable lifestyle, while memories offer emotional sustenance, a sense of identity, and a connection to loved ones. At Retire with Equity, we suggest everyone create an emergency fund of at least 5% of their retirement savings. One primary purpose of this fund is to pay for unexpected healthcare needs, such as assisted living or hiring caregivers. Given that basic financial needs are met, memories—those intangible, priceless moments—tend to provide the most incredible comfort in old age. They remind us of the richness of life, the love we’ve shared, and the experiences that have shaped who we are. While money offers external comfort, memories provide internal peace, warmth, and solace as we navigate the later stages of life. Ultimately, what will comfort us in our golden years is not how much money we have in the bank but how much life we’ve genuinely lived. Don't retire---Re-Wire
Patients undergoing radiation therapy for certain types of cancer at ChristianaCare’s Helen F. Graham Cancer Center & Research Institute will be the first in Delaware to benefit from a cutting-edge treatment system that increases accuracy and precision, enhances patient comfort and minimizes side effects. ChristianaCare expects to begin scheduling patients in early 2026 to receive treatment with the Varian Ethos™ system equipped with HyperSight. The innovative radiotherapy system leverages artificial intelligence and the fastest on-table imaging in the field to enhance precision and increase the likelihood of effectively treating tumors. “As leaders in cancer treatment and care, we continually strive to stay at the forefront of medicine for our patients, and this new technology is a game-changer,” said Thomas Schwaab, M.D., Ph.D., Bank of America endowed medical director of ChristianaCare’s Helen F. Graham Cancer Center and Research Institute. “Adaptive radiation therapy enables members of the patient’s treatment team to create a new treatment plan every day in real-time based on the patient’s needs and anatomy in that moment as well as any changes observed during their therapy.” In traditional radiotherapy, a plan is established at the beginning of treatment and followed through the treatment course. Adaptive radiotherapy allows for real-time modifications to the plan based on periodic assessments while the patient is on the radiation table. Human anatomy changes quickly through normal bodily function even during treatment. In the context of radiation therapy, even slight shifts or alterations in the body while being treated can significantly impact effectiveness. The advanced technology in the system enables real-time imaging on the radiation table to be completed in seconds, rather than minutes – a dramatic improvement that transforms targeting accuracy and patient comfort. “This advancement will allow us to deliver personalized treatments, enabling radiation oncologists to make necessary treatment decisions even more quickly and accurately,” said Lindsay Romak, M.D., radiation oncologist at the Graham Cancer Center. “This will provide clinically meaningful benefits for patients who require radiotherapy for a wide range of cancers, including those of the prostate, bladder, abdomen and head and neck.” Artificial intelligence powers patient treatments Leveraging the power of artificial intelligence to capture and analyze rapid images in real time, the technology quickly detects changes in the patient’s anatomy and tumor size, shape or position. Using real-time imaging data, the system automatically suggests adjustments to the treatment plan to account for these changes, which is key to achieving better patient outcomes. The system also uses artificial intelligence when determining the distribution of the radiation dose, ensuring the tumor receives the optimal amount of radiation. This streamlines the workflow making the entire process of adaptive radiotherapy more efficient. "The integration of artificial intelligence into our treatment processes underscores our dedication to incorporating the most innovative treatments for our patients. With this technology, our patients can anticipate shorter treatment times and potentially fewer sessions, significantly enhancing their overall experience,” Laura Doyle, Ph.D., chief clinical physicist at the Graham Cancer Center said. Adaptive radiation therapy is covered by Medicare and most insurance carriers. The system will be located in the radiation oncology suite at the Graham Cancer Center. Equipment installation is expected in the fall of 2025 with patient use starting in early 2026. ChristianaCare’s Radiation Oncology Department is recognized by the American Society of Radiation Oncology Accreditation Program for Excellence. Its radiation oncologists are leaders in adapting the very latest imaging and treatment advances into clinical practice. The team also helps write the standards for best practices in care delivery and teaches other doctors and health care professionals in this specialty. With this latest advancement, ChristianaCare’s Helen F. Graham Cancer Center and Research Institute continues to solidify its position at the forefront of cancer care in Delaware and beyond, underscoring its commitment to improving patient outcomes and quality of life.
New Trends and Treatments in Menopause Care
If you’re in your 40s and you menstruate, you may already be experiencing the effects of menopause: the point in life when your menstrual cycle stops permanently, which arrives for most people around the age of 50. This hormonal shift comes with numerous symptoms, some of which are manageable with at-home care and others—like intense mood swings, hot flashes or trouble sleeping—may need medical attention. Menopause has officially happened when a year has passed since your last period. The roughly two to eight years before that, when periods become irregular and fertility decreases, is known as perimenopause. Some people experience perimenopause in their 30s and some as late as their early 50s, but most reach perimenopause in their late 40s. Menopause is a naturally occurring life change, not a disease, and not everyone requires treatment for it. Many people seek medical help to deal with their symptoms. There are many new trends in menopause care, from hormones to drugs to supplements and beyond, and navigating them may feel overwhelming. What’s safest for managing side effects? Should I buy over-the-counter treatments or seek more involved care from a health care provider—or both? Read on for answers to these and other important questions on how best to treat menopause symptoms. Is hormone therapy right for me? Menopause happens to everyone who menstruates, and it’s important to bring up any symptoms of menopause as they occur at your annual primary care checkup. A gynecologist with special training or interest in the transition from ages 40 to 55 is an ideal specialist to seek additional care and treatment from, especially if you’d like to explore medical treatments like hormone therapy. Hormone therapy in the form of prescribed estrogen and progestin (both reproductive hormones that exist in the body naturally) has been used since the 1980s to treat the symptoms of menopause. A decline in estrogen is the culprit for many menopause symptoms, so adding estrogen back into the body through hormone therapy helps to diminish symptoms. Not all people who go through menopause need hormone therapy, but it has numerous positive side effects, including the lessening of some symptoms and lowering the risk of osteoporosis, a loss of bone density that can be exacerbated by natural estrogen decreasing over time as we age. These therapies can be administered in a cream, a patch, or even through low-dose birth control pills. However, hormone therapies can carry an increased risk of some cancers, including breast cancer. Non-hormonal, complementary medicine and lifestyle options Non-hormonal options to treat menopause symptoms are growing in popularity and represent an alternative to hormone therapies. Some of these include: Be sure to consult your provider before adding any new drugs or supplements to your daily routine. There are also many popular and effective options for treating menopause symptoms that come from Eastern and herbal medicine traditions. These include acupuncture, which has been shown to help with hot flashes and night sweats, as well as herbal supplements that often accompany treatment from a trained acupuncturist. A main downside to acupuncture can be cost, as the treatment is rarely covered by insurance. Eating mindfully and exercising regularly both also have proven benefits to treat menopause symptoms and to keep our bodies healthy more broadly as we age. This includes getting enough vitamin D and calcium through diet in order to keep bones strong as hormone levels change and to limit caffeine and alcohol consumption. Challenges in menopause care Despite the progress made in menopause treatment over the past years, there are still a few main challenges that you may face in menopause care. These include: Stigmas surrounding speaking openly about symptoms, especially sexual side effects like vaginal dryness and changes in libido that can affect intimacy. It’s important for you to feel empowered to discuss all symptoms with your provider. The increased availability of at-home tests, purchased online, for menopause and perimenopause. While these tests may be helpful in showing a snapshot of your hormone levels on a given day, more information is needed to diagnose menopause and perimenopause correctly, and at-home results can often be misinterpreted. It’s best to conduct these sorts of tests under the care of your provider, who can place them in the appropriate context. It can be hard to find the time needed to diagnose and treat menopause symptoms in a clinical setting, especially because it often takes time and communication outside of an office setting to ensure diagnosis and treat symptoms properly. Seeking out a provider who specializes in menopause care helps a great deal to expedite this process and get you the care you need. Not everyone experiences menopause the same way: for some people, symptoms are mild enough that at-home remedies will meet their needs. But for those with more intense symptoms—or anyone hoping for clinical support during this challenging time—working closely with a gynecologist will bring you relief and greater insight.
AU expert talks Hurricane Helene’s impact on the supply chain
Hurricane Helene tore a path of destruction beginning at Florida’s Big Bend region and stretching up through Georgia, South Carolina, North Carolina, Tennessee and Virginia. As those affected have slowly been able to grasp the scope, a different form of trouble in the aftermath is creating a ripple effect that will be felt around the region, country and even the world. Western North Carolina is at the heart of the problem leading to sourcing, transportation and disruption issues. While still trying to understand the full scope of the impact in the most remote areas, ongoing recovery efforts continue following the storm where the death toll has risen to over 250 as of Oct. 14. According to Rick Franza, PhD, professor in the James M. Hull College of Business and an expert on operations and supply chain management, said lessons learned from the COVID-19 pandemic and the collapse of the Francis Scott Key Bridge at the Port of Baltimore incident earlier this year can help with mitigation of risk and recovering during these problematic times. “The biggest thing you’re always dealing with in situations like this is uncertainty,” said Franza. “You can’t expect everything. You can’t anticipate everything, but we learned a lot from COVID and then the Baltimore bridge collapse and the supply chain disruptions those caused.” Franza said North Carolina is a case study in disruption to the supply chain at three different points: the source, manufacturing and transportation. “When we think about supply chain disruptions, people don’t typically think about it affecting the physical supply, but rather the transportation and logistics,” said Franza. “This one’s a little trickier because you have one industry affected by the supply of raw materials, another affected by the manufacturing of supplies and so many more will be affected by transportation problems.” Problems in manufacturing One industry that has been heavily impacted by the storm is the medical field, particularly the manufacturing of IV fluid bags. Baxter International, one of the largest producers of IV fluid bags in the country, has a manufacturing plant located in Marion, North Carolina. According to the American Hospital Association, the Marion plant produces 1.5 million IV bags per day, which equates to 60% of the country’s supply. “There are two big questions affecting the supply chain for those IV fluid bags,” said Franza. “If you lose a manufacturing facility, like the one in Marion, does another facility or a competitor have the ability to add capacity, even if it’s just a short term? The other piece of it is, even if they have the capacity, do they have the raw material inputs? So it’s a ripple effect.” In the wake of the storm, Baxter announced its other manufacturing facilities would increase their capacity. Thanks to its new Mount Carmel Mega Distribution Center located in Mississippi, the company feels confident it will be able to meet the needs of hospitals across the country. Baxter plans to increase allocation levels for direct customers from 40% to 60% and for distributors from 10% to 60%. They are also increasing allocations for designated children’s hospitals by 100%. Problems at the source Just outside the town of Spruce Pine, a town of less than 2,200 people located in the Blue Ridge Mountains, are two mines that produce an estimated 80% to 90% of the world’s most pure quartz. The quartz found in those mines is used in the manufacturing of semiconductors for microchips for everything from smartphones to cars to medical devices and more. The two companies that manage those two mines, Sibelco and The Quartz Corp, shut down operations on Sept. 26 ahead of the storm. As recovery efforts continue in the region, there remains more uncertainty as the full scope of the damage continues to be realized, and there is no certain timeline for when things will get started again. “The issue with natural resources like quartz is, unless you’ve come up with some method of producing an artificial version of it, you can’t really make it somewhere else,” said Franza. “Since there isn’t currently an alternative, it then becomes a question of is the mine accessible or how long until it is accessible and people can get back to regular operations?” Problems with transportation In Western North Carolina, entire roads along with buildings and other structures were wiped out as streams and rivers surged and mudslides occurred. On top of getting the mine back up and running, there is also the problem of getting the raw quartz where it needs to go. “Once you are able to access the ability of the mine to get back online, you then have the problem of whether the raw material can get where it needs to go to be processed,” said Franza. “A big problem in western North Carolina is entire roads are gone, and it’s not a simple repave. On top of that, Interstate 40 is estimated to be shut down until sometime next year, so transportation in that area is going to be extremely difficult for quite a while.” The good news is that quartz and the microchips that it is used in are not perishable items, and some chip manufacturers may have several weeks’ worth of quartz supply built up to be able to continue production. But an extended shutdown will likely mean even more chip shortages, similar to the global chip shortage that began in 2020 and lasted through 2023 due to the COVID-19 pandemic and the tightened restrictions in the countries that manufacture those chips. The loss of roads is not the only source of recent transportation problems, as immediately following the during the storm there was a three-day disruption in imports at 36 ports, including shutting 14 down stretching from Maine to Texas, as 45,000 dockworkers went on strike over pay. While that disruption could have caused serious issues, particularly for the upcoming holiday season, Franza said many companies have learned from previous disruptions, and most of the goods needed for Cyber Monday, Black Friday and preparing for the holiday season were already in the country. “I have heard that somewhere between 80% to 90% of the items for the holidays are already here, so the dock workers’ strike would not have been as much of an issue for the holidays, but there would definitely have been things you’d run out of.” Franza said the biggest problem during situations such as this is misinformation. “One of the biggest problems is most people are uninformed,” Ranza said. “Look at the toilet paper shortage at the beginning of COVID. If all of a sudden people rush to buy everything up and hoard it all, you can’t meet that demand so it causes even more problems. People need to be better informed because rumors start and then more problems are caused.” But Franza reiterated that companies have learned from past events, and that planning has made the supply chain stronger. “I think we’re better than we were four years ago because each of these crises builds our toolbox on how to plan for and deal with disruptions. It has built resiliency.”
You’ve probably heard of – or experienced for yourself – that women crave chocolate due to PMS (premenstrual syndrome) before or even during their cycle. Some attribute this craving to a loss of riboflavin during this time. But it could also be a response to the body’s increase in hormones that contribute to cravings for sweets and fats, and chocolate has both! Ignoring those cravings isn’t going to work. However, there are ways to satisfy your body’s needs without breaking the calorie bank, overindulging in food or reaching for unhealthy options. The cycle There are essentially two phases in the menstrual cycle — follicular and luteal — which are triggered by hormonal changes. “Cycle syncing” is the process of altering diet and activity according to a woman’s naturally occurring menstrual phases each month. When you consider nutrition “cycle syncing,” which is tailoring your nutrition with your menstrual cycle throughout the month, it’s helpful to break it into four separate components: Menstruation (beginning of menstruation). Follicular. Ovulation (1st day of luteal). Luteal. What does this mean? It means this complex cycle is controlled by female hormones that cause regular bleeding (periods). Estrogen is one of the major players that helps regulate a woman’s menstrual cycle and is produced mainly by the ovaries, the same two small glands that store hundreds of thousands of tiny eggs for release over a woman’s lifetime. Eating for PMS in cycle stages Phase 1: Menstruation – “Aunt Flo” comes to visit (3-7 days) During the menstrual period, the most work happens during the first three days. This is when a woman’s flow arrives and pain onsets in the pelvis, legs, back and other areas. This is also when the most blood is lost. The cramps a woman feels serve a purpose. They are a symptom of the uterus contracting, helping to shed the endometrium (the lining of the uterus), which you may know as Aunt Flo coming to visit, also known as menstrual bleeding. Focusing on good sources of nutrition with magnesium in them may help reduce the severity of symptoms for better sleep, headaches, muscle soreness in the uterus and cramping, swelling and bloating and mood changes. Healthy fats can be useful during this phase since levels of estrogen and progesterone are typically low. We need healthy fats to help generate any kind of hormones. Look for good sources of healthy fats in seafood rich in omega-3 fatty acids, avocados, olive oil, sardines in oil, nuts and seeds, fiber, apples, berries, ground flax seed and oatmeal. Phase 2: Follicular – release the kraken! (7-10 days) Let’s face it, during the second stage of a woman’s cycle, your body is about to drop the mic! Well, not the mic per se, but your body is preparing to release an egg. That’s a lot of work. During this phase, hormones are released to signal the production of follicles on the surface of an ovary. A handful will enlarge, but only the largest and strongest follicle will ultimately release an egg during ovulation. This plays the biggest role in the length of your cycle. At the very same time, the endometrium starts to thicken in case you’re getting ready to have a baby. The last five days of this phase, plus the ovulation day (the day the egg drops), are your fertile window (baby-making time!). This is when you are most likely to become pregnant if you have sexual intercourse without using birth control. Focus on complex carbohydrates during this phase. Complex carbohydrates keep the insulin-glucagon ratio even and can help manage depression, fatigue and insomnia. Pro Tip: Between cycling, zinc can be helpful for ovulation and potentially help to support the egg quality. For women who are looking to conceive, they may want to consider using more zinc in their diet or with a supplement leading up to the follicular phase. Talk with your health care provider to see if this is a helpful option for you. Phase 3: Ovulation phase – there can be only one! (2-4 days) The three to five days leading up to ovulation and the day of ovulation itself are the most fertile. Ovulation begins on the day the egg is released from the egg follicle on the ovary. Remember when you were little and found a dandelion seedling in the grass? You grabbed it and blew on the seedlings to release them into the wind. This is similar except it’s just one egg being released. Protein is your friend during this phase. Protein will help keep your blood sugars steady, keep you feeling full and prevent cravings. Phase 4: Luteal (premenstrual) phase – winter is coming! (10-14 days) The luteal phase starts on the day the egg drops, also known as ovulation day. This happens anytime from day 7 to day 22 of a normal menstrual cycle. After the teen years and before perimenopause (the time before menopause), the luteal phase is very predictable. It normally lasts 13 to 15 days from ovulation until menstrual bleeding starts a new cycle. These two weeks are also known as the premenstrual period. It’s very common to have symptoms during all or part of the luteal phase. You may feel irritable and cranky, gain water weight and feel bloated. A day or more before your period, you may start to have pain (cramps) in your belly, back or legs. It’s normal to have less energy at this time. Don’t panic, and don’t get down on yourself for needing to rest or nap. You may also have headaches, diarrhea or constipation, nausea or dizziness. When premenstrual symptoms make your daily life difficult, you are said to have premenstrual syndrome (PMS). Good dietary sources during the luteal phase should include calcium. Calcium can help reduce the severity of PMS symptoms, including bloating, depression, pain, mood swings and food cravings. Pro tip: It may be difficult to get all the calcium necessary to help with general PMS symptoms. While we recommend getting as much calcium as possible in your diet, check with your health care provider for guidance on nutrition and supplementation. According to the American College of Obstetricians and Gynecologists, 1,200 milligrams of magnesium is usually recommended to help reduce the physical and mood symptoms of PMS. Everyone metabolizes food and supplementation differently. Results will vary. The role of iron Consider increasing iron and iron sources, especially during the luteal phase leading up to the menstruation phase. The leading cause of iron deficiency and anemia is a woman’s cycle. The more that women boost their iron stores before their menstruation cycle, the better. Look to increase iron consumption through animal sources, legumes or fortified cereals. Some women might need supplementation or other medical interventions. Sometimes, other conditions cause heavy menstrual cycles or reasons for medical intervention. Follow up with your health care provider Women may have menstrual-related conditions needing treatment beyond lifestyle changes alone. Seek care for: Irregular periods (not due to medication or breastfeeding). Heavy menstrual bleeding or severe menstrual pain. Significant depression and/or anxiety around the menstruation cycle. Menstrual cycles can have many different symptoms and associated medical conditions. Making lifestyle modifications is helpful, but if you’re experiencing severe or concerning symptoms, these should always be discussed with a health care provider.
National Institutes of Health award $1.827 million for research on collective cell migration
Priscilla Hwang, Ph.D., assistant professor in the Department of Biomedical Engineering at Virginia Commonwealth University, has received a National Institutes of Health grant for $1.827 million over five years. The award from the National Institute of General Medical Sciences will support Hwang’s innovative research project “Dissecting mechanisms of collective migration” and provide mentorship for student researchers from the high school to graduate level. Collective migration, where groups of cells move together in a coordinated manner, is critical for the successful development of tissues and plays a vital role in wound healing, metastasis, and other biological processes. Dysregulation in collective migration is often linked to developmental abnormalities and disease progression. Despite its importance, the mechanics and mechanisms driving collective migration remain poorly understood. The project is organized around three primary goals: Investigate the effect of biomechanical cues to activate leader cells and directional collective migration: Understand how biomechanical signals activate leader cells to guide the migration of cell groups. Elucidate which and how leader cell mechanics are responsible for leader cell development: Identify the specific mechanical properties and behaviors that enable leader cells to emerge and lead the collective migration process. Examine the role of cell junctional forces in collective migration: Explore how the forces at cell contacts contribute to the overall migration and coordination among cells. Hwang will leverage her expertise in 3D microphysiological systems to study collective migration in dynamic, physiologically relevant environments. Her work aims to uncover the mechanisms by which leader cells sense and respond to mechanical forces in their environment, driving the collective migration of cells. “Our understanding of collective migration, especially the mechanics and mechanisms driving this phenomenon, is very limited,” Hwang said. “Our proposal will significantly accelerate our progress toward a comprehensive understanding of collective migration and lay the foundation for advancing treatment for developmental abnormalities or diseases.” The NIH grant will also expand student research and mentoring opportunities. “This Maximizing Investigators Research Award (MIRA) only goes to the most highly talented and promising investigators, and Dr. Hwang is most deserving,” said Rebecca L. Heise, Ph.D., Inez A. Caudill, Jr. Distinguished Professor and chair of the Department of Biomedical Engineering . “The award will provide support for undergraduate and predoctoral research opportunities in this important area of fundamental research that has an impact on neonatal development, cancer, and fibrotic disease.” To ensure diverse perspectives are considered throughout the project, Hwang said students from diverse populations will be recruited, including underrepresented minorities, women, and first-generation college students. “Further, we will continue to share our passion for science with the community through developing hands-on outreach activities based on our research findings,” she added.
‘You Can Do and Be Anything Coming From an HBCU’
A late July dinner was the finale to her second internship with ChristianaCare for Tania Paden. Her eight weeks at Christiana Hospital had left her feeling more confident in herself and excited to continue exploring direct patient care as she prepares to head back to Delaware State University in the fall. “I learned how to be more comfortable with direct patient care and communicate with the patients,” Paden said. “My favorite thing would have to be going to tour the different units and getting shadowing experiences throughout the hospital.” Paden is one of 10 Future of Health Scholarship Program recipients at ChristianaCare. Graduates from Delaware high schools attending Historically Black Colleges and Universities (HBCUs) were each awarded a $12,500 annual scholarship and a paid summer internship in 2021 each year until they graduate. The program, a partnership between ChristianaCare and the HBCU Week Foundation, is designed to help support HBCU students as they pursue degrees in health care. Teachable moments and big opportunities Paden’s enthusiasm is shared by Natalie Torres, director of Inclusion & Diversity at ChristianaCare, who oversees the scholarship program. “This experience is so much more than offering the scholarship funding,” Torres said. “It’s the time, it’s those quiet moments in-between meetings and their experiences where the teachable moments really take place. “When they come to us, we really want to lock into their lived experiences, and not only make sure they can thrive at ChristianaCare, but in life.” With these scholarships and other community-based endeavors, ChristianaCare continues to work to build a diverse workforce and represent its communities. Forbes recently listed ChristianaCare as one of America’s Best Employers for Diversity for the fourth year in a row. Although she is a young intern herself, Aniyah Barnett, a rising biochemistry junior at Hampton University, jumped at the chance to help make new caregivers feel comfortable at ChristianaCare. She played a key role welcoming medical and dental residents to campus. “My favorite project was probably the new resident orientation,” Barnett said. “I spent time getting all the new residents together, making sure they have all the information they need, and getting to meet them!” A pathway to medicine For Ashley Christopher, Esq., founder and CEO of HBCU Week Foundation, these scholarships mean a lot. Ten years ago, Christopher had a stroke that left her feeling scared and alone as she lay in hospital. Her cardiologist, a Black woman, was the only one who made her feel heard, she told the students during their summer-end dinner. With IT experiences gained at ChristianaCare, Future of Health scholar Solomon Devard is thinking about continuing on that path to become a system administrator for a big corporation. “She was the only one who made me feel safe, secure and seen during a time where I was questioning life as I knew it,” Christopher said. “You can do and be anything coming from an HBCU. This scholarship gives students who want to go to HBCUs a pathway to the field of medicine for more people who look like me to tend to the care of patients.” The HBCU Week Foundation creates opportunities through coaching and scholarships for students who want to attend HBCUs. To support these efforts, ChristianaCare committed $500,000 to providing financial and networking support, and hands-on experiences for HBCU students. “These students are energized, they’re talented, and I’m so excited for the next step,” Christopher said. “I just feel so happy to be a part of that process.”
