Experts Matter. Find Yours.

Connect for media, speaking, professional opportunities & more.

Interested in the true pursuit of greatness? Take a look at what Florida Tech has to offer featured image

Interested in the true pursuit of greatness? Take a look at what Florida Tech has to offer

If you are up for the challenge and want to begin your own relentless pursuit of greatness, let us help. The Florida Tech campus is located in the heart of Florida’s Space Coast. That means proximity to key agencies and operations, such as NASA-Kennedy Space Center, SpaceX, Embraer, L3Harris Corporation, Northrop Grumman and more. Oh, and did we mention there are miles and miles of Atlantic Ocean beaches just moments away?  Learn more about all Florida Tech has to offer. Get in touch today! Simply contact: Adam Lowenstein Director of Media Communications (321) 674-8964 adam@fit.edu

1 min. read
Researchers seek to find new ways of building permanent magnets, reducing dependency on rare-earth elements featured image

Researchers seek to find new ways of building permanent magnets, reducing dependency on rare-earth elements

Permanent magnets play an indispensable role in renewable energy technologies, including wind turbines, hydroelectric power generators and electric vehicles. Ironically, the magnets used in these “clean energy” technologies are made from rare earth elements such as neodymium, dysprosium and samarium that entail environmentally hazardous mining practices and energy-intensive manufacturing processes, according to Radhika Barua, Ph.D., mechanical and nuclear engineering assistant professor. Access to these rare earth magnets is also heavily reliant on China and demand for them is expected to grow as the U.S. seeks to meet net-zero carbon emissions by 2050. “That anticipated demand poses a challenge to U.S. decarbonization goals as the rare earth elements are characterized by substantial market volatility and geopolitical sensitivity,” Barua says. “This is where our project comes in.” Barua and fellow VCU professors Afroditi Filippas, Ph.D., and Everett Carpenter, Ph.D., are part of a team of VCU researchers working to create new types of magnets. By using additive manufacturing, more commonly known as 3D printing, they hope to create replacements for those permanent magnets composed of rare earth elements that are made from materials readily available in the U.S. China mines 58 percent of the global supply of rare earth elements used to make neodymium magnets that are widely used in consumer and industrial electronics, the U.S. Department of Energy (DOE) noted in a February 2022 report. That dominance grows throughout the manufacturing process with China accounting for 92 percent of global magnet production, the DOE estimates. “It would be ideal if we could manufacture the same magnets with the same characteristics without using rare earth elements,” says Filippas, who teaches electromagnetics at VCU. “It would be even better if we could make these magnets using additive manufacturing techniques.” VCU researchers are trying to do that in collaboration with the Commonwealth Center for Advanced Manufacturing (CCAM), which brings university, industry and government officials together to tackle manufacturing challenges. The professors are conducting much of their work at CCAM’s lab in Disputanta, Virginia. “We have access to equipment that we would not have access to at VCU,” Filippas says of the benefits of the CCAM partnership. “They provide that level of expertise using the equipment and understanding the process.” The project is funded by the VCU Breakthroughs Fund and CCAM. Barua is working with Carpenter, a chemistry professor, on the materials science part of the project. Filippas is focusing on data analytics and is helping develop a monitoring process to ensure the newly-crafted replacement magnets are viable. In addition to providing a more stable source of supply, Barua says the replacement magnets could also bring environmental benefits. Providing an alternative to rare earth magnets would involve less hazardous mining techniques while also reducing emissions and energy consumption. The replacement magnets are made by filtering particles of iron, cobalt, nickel and manganese through a nozzle where a laser fuses them together through a process known as direct energy deposition. That metal 3D printing approach can make complex shapes while minimizing raw material use and manufacturing costs, Barua says. “Right now, we’re printing straight lines just to see what we’re going to get and see if we can even print them,” Filippas says. “Are we getting the composition of the materials that we want? It’s a slow painstaking process towards freedom from reliance on rare earth materials.” Barua says using additive manufacturing allows researchers to create a unique microstructure layer-by-layer instead of simply making magnets from a cast. Researchers do not expect their replacements to mimic the full strength of rare earth magnets, but they hope to produce mid-tier magnets that are as close as possible to current magnets. Carpenter adds their new magnets could potentially be smaller and weigh less than rare earth magnets, which could lead to numerous benefits. “This reduction would be a big savings to the automobile manufacturing industry, for example, where every ounce matters,” Carpenter says. “In an S-Class Mercedes, there are over 130 magnets used in sensors, actuators or motors. This approach could save pounds of weight which translates into fuel efficiency.” Barua says the team is working to establish the feasibility of their new magnet-making process. They are trying to get the microstructure of the new magnets just right and are using additive manufacturing to fine-tune their magnetic properties, Barua says. “When artificial diamonds, cubic zirconia, was synthetically produced in the lab, it changed the entire diamond industry,” Barua says. “That’s exactly what we’re trying to do. We’re trying to make synthetic magnets.”

Radhika Barua, Ph.D. profile photoAfroditi V. Filippas, Ph.D. profile photo
3 min. read
Researcher to build fuel database to improve nuclear reactor sustainability featured image

Researcher to build fuel database to improve nuclear reactor sustainability

Braden Goddard, Ph.D., assistant professor in the Department of Mechanical and Nuclear Engineering, has received a grant from the U.S. Department of Energy’s Nuclear Energy University Program (NEUP) to create a database for use in nuclear material control of pebble bed reactors (PBR). Advances in material science and technology have revitalized the nuclear energy industry, allowing for the design and construction of advanced nuclear reactors. New high-temperature materials developed by researchers allow ideas from as early as 1970, like pebble bed reactors, to be re-explored and make nuclear power more efficient and sustainable. Pebble bed reactors are one of many ideas from as early as 1970 that researchers are once again exploring to make nuclear power more efficient and sustainable now that science has developed new high-temperature materials. “Imagine a gumball machine,” said Goddard, “A pebble bed reactor functions similarly. The pebbles are the gumballs, which are fed into a reservoir. As they make their way through the reactor, heat generated from the radiation is removed by a gas which then spins an electrical turbine to generate electricity. The pebbles then exit from the bottom of the reservoir and those that can be reused are returned to the top of the reservoir.” Each pebble contains thousands of microscopic uranium particles encased in silicon-carbide cladding. As the pebble passes through the PBR, the path it follows affects how much fissioning occurs within the uranium. This means pebbles deplete at different rates based on how they travel through the reactor. Goddard’s database seeks to characterize the state of a pebble after it leaves the PBR by determining precisely how much plutonium and uranium remains in the pebble. This informs PBR operators if the pebble can be reused or if it needs to be sent off as waste. Better characterizing these pebbles improves the sustainability and security of PBRs while reducing the amount of waste generated. Measuring gamma radiation from the radioactive isotope cesium-137 created from the fission of uranium is the traditional method of determining how much nuclear fuel is still viable. However, this system does not work for PBRs because the correlation between the uranium fuel and the gamma radiation it emits is not consistent between pebbles. To remedy this, Goddard will measure both gamma and neutron radiation emitted by all radioactive isotopes in the pebble, which varies depending on the route the pebble takes through the reactor. Partners like Brookhaven National Laboratory and similar institutions within the United States will assist in the research by applying machine learning techniques to the gamma and neutron radiation signature. “Nuclear reactor operators have instruments that tell them what’s going on inside the reactor, but it’s not the same as knowing how much uranium mass you have in fuel going into or coming out of the reactor,” said Goddard. Goddard and his colleague, Zeyun Wu, Ph.D., will use computer modeling to run countless simulations and map every possible course a pebble can take through a PBR. The resulting catalog of data will allow PBR operators to characterize the state of any pebble leaving the PBR and assess if it can be reused or if it is ready to be stored at a nuclear waste facility. The catalog also serves as a material inventory, allowing nuclear facilities to better track waste material.

Braden Goddard, Ph.D. profile photoZeyun Wu, Ph.D. profile photo
3 min. read
#Expert Research: New National Science Foundation and NASA-Funded Research Investigates Martian Soil featured image

#Expert Research: New National Science Foundation and NASA-Funded Research Investigates Martian Soil

Studies have shown crops can grow in simulated Martian regolith. But that faux material, which is similar to soil, lacks the toxic perchlorates that makes plant growth in real Red Planet regolith virtually impossible. New research involving Florida Tech is examining how to make the soil on Mars useful for farming. Andrew Palmer, co-investigator and ocean engineering and marine sciences associate professor, along with Anca Delgado, principal investigator and faculty member at Arizona State University’s Biodesign Swette Center for Environmental Biotechnology, and researchers from the University of Arizona and Arizona State University, are participating in the study, “EFRI ELiS: Bioweathering Dynamics and Ecophysiology of Microbially Catalyzed Soil Genesis of Martian Regolith.” This National Science Foundation and NASA-funded project will use microorganisms from bacteria to remove perchlorates from Martian soil simulants and produce soil organic matter containing organic carbon and inorganic nutrients. Martian regolith contains high concentrations of toxic perchlorate salts that will impede plant cultivation in soil, jeopardizing food security and potentially causing health problems for humans, including cancer. Researchers will look at different bacterial populations and how well they are able to process and break down the perchlorates, as well as what kind of materials they produce when they do. They’ll also look at different temperatures and moisture conditions, as well as in the presence or absence of oxygen. Students in the Palmer Lab will receive the simulants after this process, try to replicate it, and then test how well the perchlorate-free regolith is able to grow plants. A challenge the researchers face is how they remove the toxic salts, as well as if they can remove all of them. Palmer cautioned that the possibility that removing the perchlorates does not necessarily mean the regolith is ready for farming. “You can’t make the cure worse than the disease, so we have to be ending up with regolith on the other side that’s better than when we started,” Palmer said. “We can’t trade perchlorates for some other toxic accumulating compound. Just because we’re removing the perchlorates doesn’t necessarily mean that we’re going to make the regolith better for plants. We might just make it not toxic anymore. How much does it improve is really what we’re trying to figure out.” Even without perchlorates, there are significant challenges to growing crops in Martian soil. While researchers have grown plants in simulated regolith, the regolith is not good for plant growth, as in addition to a lot of salts, it has a high pH and is very fine, which means it can ‘cement’ when wet, suffocating plant roots. Being able to grow in the soil instead of using hydroponics could also provide a more efficient, cost-effective solution. “There is always the option of hydroponic growth of food crops, but with a significant distance to Mars and the lack of readily available water, we need a different kind of plan,” said ASU’s Delgado. “If there is a possibility to grow plants directly in the soil, there are benefits in terms of water utilization and resources to get supplies to Mars.” Some of the microbial solutions the team is proposing could also help with studies of soils on Earth. “The best soils for agriculture on earth, they were taken up decades ago, and so now we’re trying to farm on new land that’s not really meant for agriculture, if you think about it,” Palmer said. “So, as we think about ways to convert it into better soil, I think this research helps teach us how to do that, but it also inspires.” The research will also allow Florida Tech students to get hands-on space agriculture experience. “We’re going to be training the grad students and the undergraduates who are going to be the researchers who take on those new challenges, so I think one of our most important products are going to be the students we train,” Palmer said. “We’ll deliver Mars soil, but we also deliver, I think, a future group of researchers.” If you're a reporter looking to know more about this topic - then let us help with your coverage. Dr. Andrew Palmer is an associate professor of biological sciences at Florida Tech and a go-to expert in the field of Martian farming. Andrew is available to speak with media regarding this and related topics. Simply click on his icon now to arrange an interview today.

Andrew Palmer, Ph.D. profile photo
3 min. read
Aston University photonics expert elected as Fellow of Optica featured image

Aston University photonics expert elected as Fellow of Optica

• Professor Edik Rafailov is head of the Optoelectronics and Biomedical Photonics Research Group • He is a member of Aston Institute of Photonic Technologies, a world-leading photonics research centre • Optica is the leading organisation for researchers and others interested in the science of light. A photonics expert at Aston University has been elected as a Fellow of Optica (formerly OSA), Advancing Optics and Photonics Worldwide. Professor Edik Rafailov is head of the Optoelectronics and Biomedical Photonics Research Group in the College of Engineering and Physical Sciences at Aston University and a member of Aston Institute of Photonic Technologies (AIPT), one of the world’s leading photonics research centres. He was elected for his ‘contributions to novel gain media for semiconductor lasers at wavelengths from 750nanometres to1300nanometres’. Optica is the society dedicated to promoting the generation, application, archiving and dissemination of knowledge in the field of photonics. Founded in 1916, it is the leading organisation for scientists, engineers, business professionals, students and others interested in the science of light. Fellows are selected based on several factors, including outstanding contributions to business, education, research, engineering and service to Optica and its community. Satoshi Kawata, 2022 Optica president, said: “I am pleased to welcome the new Optica Fellows. These members join a distinguished group of leaders who are helping to advance the field optics and photonics. Congratulations to the 2023 Class.” Director of AIPT, Professor Sergei Turitsyn said: “I am delighted that Edik has received this prestigious fellowship. “AIPT has one more Optica Fellow, that is a high honour in the field of photonics. “Edik joined Aston University in 2014 and since then his research has contributed to the Institute’s world-leading position in the fields of fibre and semiconductor lasers and bio-medical photonics, making impact on industry, scientific communities and society.” Fellows are Optica members who have served with distinction in the advancement of optics and photonics. As they can account for no more than 10 percent of the total membership, the election process is highly competitive. Candidates are recommended by the Fellow Members Committee and approved by the Awards Council and Board of Directors. The new Optica Fellows will be honoured at the Society’s conferences and events throughout 2023.

Edik Rafailov profile photo
2 min. read
Aston University bioenergy expert urges government to use COP27 to move consumers away from fossil fuel use featured image

Aston University bioenergy expert urges government to use COP27 to move consumers away from fossil fuel use

COP27 should be turning point to switch from heating homes with fossil fuels Professor Patricia Thornley, was a presenter at COP26 in Glasgow She believes one year on there’s not enough progress to cut emissions from homes. One of the UK’s leading bioenergy experts has said COP27 should be a turning point to help UK consumers switch from heating their homes with fossil fuels. Professor Patricia Thornley, director of Aston University’s Energy and Bioproducts Institute (EBRI), was a presenter at COP26 in Glasgow last year. She leads the UK’s national bioenergy research programme, SUPERGEN Bioenergy hub. Her research focuses on assessing the sustainability of bioenergy and low carbon fuels. Professor Thornley believes that one year on, not enough has been done to encourage the public to cut down on the emissions their homes produce. The UK has the oldest housing stock among developed countries, with 8.5 million homes being at least 60 years old. That is despite COP26’s reaffirmation of the Paris Agreement goal of moving away from fossil fuels, and the call for stronger national action plans to reduce carbon dioxide emissions. She has welcomed initiatives to help some UK industries move towards net zero, but believes householders are not getting the same support, for example with help to insulate their homes more effectively. She said: “Responses to the energy crisis in which we find ourselves have been mixed. “Government initiatives such as funding feasibility studies for hydrogen from bioenergy (turning biomass into hydrogen whilst separating and capturing the carbon portion of the biomass) and other technologies are promising.” Professor Thornley adds: “The recent price hikes in petrol and natural gas highlight the extent to which the UK relies on fossil fuels. “Unlike some areas of industry, domestic consumers have been treated differently, and recent help with energy costs is arguably subsidising us to keep emitting carbon dioxide. “A more forward-thinking approach would have been to invest in tackling the root cause of the problem by addressing home insulation.” Professor Thornley is a fellow of the Royal Academy of Engineering, and recently gave evidence to the Environmental Audit Committee about the use of sustainable timber in the UK as an alternative fossil fuel.

Patricia Thornley profile photo
2 min. read
Gene Editing Institute Travels to Salem for ‘Innovation Days’ Workshop featured image

Gene Editing Institute Travels to Salem for ‘Innovation Days’ Workshop

Education sessions bring CRISPR gene editing to high school students from diverse backgrounds Scientist-educators from ChristianaCare’s Gene Editing Institute held a workshop using CRISPR in a BoxTM at Salem Academy during Innovation Days in October at the school, located in Winston-Salem, North Carolina. These sessions followed a previous gene editing education workshop with Salem Academy students in January 2022. CRISPR in a BoxTM is a revolutionary toolkit that allows students to carry out a hands-on gene editing experiment while learning and analyzing the steps involved in a typical gene editing reaction. Scientists from the Gene Editing Institute also taught a condensed lesson about CRISPR gene editing’s utility in medicine and fielded questions from students about jobs in biotechnology, bioethics and sustainability in the lab. “It’s a really special opportunity that I know I wouldn’t get anywhere else,” said Mathilda Willenborg, a sophomore boarding student from Germany. “And I do feel like I’m learning a lot about gene editing that I definitely didn’t know before. The team makes it really easy and walks us through all the steps.” Last winter, Salem Academy became the first school in North Carolina to offer CRISPR in a Box as it pivoted its academic focus to STEAM (Science, Technology, Engineering, Art and Math). That first innovative workshop originated as a result of an idea from a ChristianaCare board member who attended Salem Academy. Gene Editing Institute Founder and Lead Scientist Eric Kmiec, Ph.D., made a virtual appearance as part of the latest sessions to encourage the students to pursue careers and pathways in biotechnology. “We’re so appreciative of our partnership with Salem Academy,” said Kmiec. “We want to take every chance we get to encourage more women to pursue careers in STEM. Women around the nation, and around the world, should have access to this groundbreaking technology, which will ultimately drastically change the way we treat and cure diseases. If we don’t have young women in that discussion, we’re missing out on valuable experiences and perspectives.” Salem Academy is the only all-female boarding and day high school on a college campus in the U.S. with a STEM focus. Women are achieving significant progress in STEM fields, representing 45% of students majoring in STEM, according to the Integrated Postsecondary Education Data System. However, women only represent 27% of STEM workers, with wide disparities in income in post-graduation employment. As of 2019, less than 30% of the world’s researchers were women, according to the UNESCO Institute for Statistics. The Gene Editing Institute commits to a mission of diversity and equity in its approach. This workshop reached 10 women, two of whom are international students. “Our ongoing partnership with the ChristianaCare Gene Editing Institute will help position our aspiring women scientists for future careers in biotechnology, science and medicine,” said Summer McGee, Ph.D., president of Salem Academy and College. “This is the type of experience that sets Salem Academy apart as a national leader in building the next generation of women leaders in STEAM.” The Gene Editing Institute itself is a national leader in female researchers. Women make up over 80% of scientists within the Institute and fill 75% of the principal investigator roles. The Institute pushes to address the gender gap and promote inclusivity through local outreach and state-spanning programs, like CRISPR in a Box. “We’re not here to do lip service,” said Brett Sansbury, Ph.D., principal investigator of the Discovery Branch of the Gene Editing Institute. “Too many companies make a plan or promise without any actionable steps. We’re taking those steps and bringing in opportunities for students who otherwise wouldn’t have had them.” To learn more about how to bring CRISPR in a Box to your school, visit https://geneeditinginstitute.com/products/education. About CRISPR in a BoxTM CRISPR in a BoxTM is the leading educational toolkit to teach gene editing. The exercise features a hands-on gene editing experiment, including a live readout within non-infectious E. coli bacteria. These experiments follow a gene editing reaction from beginning to end while teaching students the techniques scientists use to perform these reactions in real laboratory environments. CRISPR in a Box is distributed by Carolina Biological. To learn more, visit https://geneeditinginstitute.com/products/education.

Eric Kmiec, Ph.D profile photo
3 min. read
Aston University researchers ‘feed’ leftover coffee grounds to microalgae to produce low emission biodiesel featured image

Aston University researchers ‘feed’ leftover coffee grounds to microalgae to produce low emission biodiesel

High quality biodiesel produced from microalgae ‘fed’ on leftover coffee grounds Breakthrough in the microalgal cultivation system Could decrease reliance on palm oil to produce biofuel. Two Aston University researchers have produced high-quality biodiesel after ‘feeding’ and growing microalgae on leftover coffee grounds. Dr Vesna Najdanovic, senior lecturer in chemical engineering and Dr Jiawei Wang were part of a team that grew algae which was then processed into fuel. In just the UK, approximately 98 million cups of coffee are drunk each day, contributing to a massive amount of spent coffee grounds which are processed as general waste, often ending up in landfill or incineration. However the researchers found that spent coffee grounds provide both nutrients to feed, and a structure on which the microalgae (Chlorella vulgaris sp.) can grow. As a result, they were able to extract enhanced biodiesel that produces minimal emissions and good engine performance, and meets US and European specifications. The study, Enhancing growth environment for attached microalgae to populate onto spent coffee grounds in producing biodiesel, appears in the November 2022 issue of Renewable and Sustainable Energy Reviews. Up till now, algae has been grown on materials such as polyurethane foam and nylon that don’t provide any nutrients. However, the researchers found that microalgal cells can grow on the leftover coffee without needing other external nutrients. They also found that exposing the algae to light for 20 hours a day, and dark for just four hours days created the best quality biodiesel. Dr Najdanovic said: “This is a breakthrough in the microalgal cultivation system. “Biodiesel from microalgae attached to spent coffee grounds could be an ideal choice for new feedstock commercialisation, avoiding competition with food crops. “Furthermore, using this new feedstock could decrease the cutting down of palm trees to extract oil to produce biofuel. “In southeast Asia this has led to continuous deforestation and increased greenhouse gas emissions.” The research was developed in collaboration with colleagues from Malaysia, Thailand, Egypt, South Africa and India. Their work was supported by the 2020-21 Global Challenges Research Fund (GCRF) block grant funded by the UK Research and Innovation (Aston University).

2 min. read
Aston University welcomes minister for tech and the digital economy for tour of new Institute of Technology Hub featured image

Aston University welcomes minister for tech and the digital economy for tour of new Institute of Technology Hub

The minister for tech and the digital economy met with representatives from Aston University’s College of Engineering and Physical Sciences and Solihull College & University Centre during a visit to the new Greater Birmingham and Solihull Institute of Technology (GBSIoT) Hub on 2 August. Damian Collins MP was given a tour of the new facility by Rosa Wells, executive director for employment and skills and IoT at Solihull College & University Centre. The Institute of Technology focuses on engineering and advanced manufacturing and is a partnership between local further education colleges, universities and industry partners. It will support learners from across the region to progress to high-skill technical jobs in industry through clear, supported pathways. Construction of the GBSIoT Hub building is nearing completion and will be welcoming students in the coming weeks. During the visit, the minister was shown the cyber physical manufacturing rig, a scaled-down version of a factory of the future, which will create a simulated working environment for IoT learners. The minister then met with executive dean Professor Stephen Garrett and deputy dean Professor Kate Sugden for a tour of Aston University’s Advanced Prototyping Facility conducted by senior project manager Paul Gretton. The facility supports businesses by increasing awareness of the opportunities available through 3D printing to improve the efficiency and effectiveness of existing designs, and to develop new products all the way through to producing prototypes. The visit also included a showcase of Aston University’s Autopod, a state-of-the-art autonomous vehicle funded by the Greater Birmingham and Solihull Local Enterprise Partnership and the Institute of Technology which is used for research and as a teaching tool. Professor Garrett said: “Aston University has a proud history of delivering high-quality technical education and world-leading research. We were delighted to be able to showcase our facilities to Damian Collins MP, whilst discussing our commitment to equipping students with the knowledge and skills they need to succeed in STEM careers.” Damian Collins MP said: “It’s been brilliant to visit the pioneering facilities at Aston University today, especially seeing the cyber rig which will give students first class training to enter the industry with confidence. “Having these opportunities will help young people gain skills they need for future jobs, supporting the UK’s world leading advanced manufacturing and digital industries.” The minister toured the facilities at Aston University as part of his wider visit to the Birmingham 2022 Commonwealth Games. For more information about the College of Engineering and Physical Sciences please visit our website.

2 min. read
Physical models of a patient’s brain help researchers treat neurological disorders and diseases featured image

Physical models of a patient’s brain help researchers treat neurological disorders and diseases

Brain phantoms are a creative solution for a challenging question: How do you tune an electromagnetic field to a patient without testing on the actual patient? Transcranial magnetic stimulation (TMS) is an application of electromagnetic research with the potential to change the way we treat migraines, depression, obsessive compulsive disorder and even conditions like schizophrenia and Parkinson’s disease. Ravi Hadimani, Ph.D., associate professor of mechanical and nuclear engineering, leads a team of researchers who seek to use TMS to excite or inhibit brain neurons to alter specific brain functions and treat these conditions. This team includes faculty from VCU Health, including Mark Baron, M.D., professor of neurology and Kathryn Holloway, M.D., professor of neurosurgery, as well as outside collaborators like Joan Camprodon, M.D., associate professor of psychiatry at Harvard Medical School. “The brain phantom is a first step,” says Hadimani, “Our ultimate goal is to 3D print a brain fabricated with biomaterial scaffolds and printed neurons that produce a stimulation response similar to neurons in our brain. This model would behave more realistically than current brain phantoms. Our future work involves collaborating with researchers who are able to print lab-grown neurons on biomaterial scaffolds or researchers who directly fabricate artificial neurons onto any scaffold.” Coils used in TMS are responsible for generating the electromagnetic field used in treatment. Individual coils are designed to treat specific diseases, but additional settings like current strength, number of pulses and coil direction are unique to each patient. Refining these settings on the actual patient is not feasible. Computer modeling is also inefficient because creating head models and running simulations from MRI scans of the brain’s complex structure are not spontaneous. Hadimani and his team developed the brain phantom as a novel solution to this problem. In 2018, the first model was created by Hamzah Magsood, one of Hadimani’s Ph.D. students. The brain phantom is a physical model of a patient’s brain designed to specifications obtained from MRI scans. Materials used in brain phantom construction are designed to replicate the electrical conductivity and electromagnetic permeability of different brain sectors. The result is a representation that, when connected to electrodes, provides instantaneous feedback to researchers calibrating TMS coils. Elements of material science, electromagnetics and mechanical prototyping come together to create each brain phantom. The process starts with an MRI, which serves as a map for researchers designing the customized model. This is a careful process. Unlike other areas of the body with clear distinguishing features, like skin, muscle and bone, the brain has subtle differences between its many regions. Researchers must carefully distinguish between these areas to create an accurate brain phantom that will simulate a patient’s skin and skull as well as the brain’s gray and white matter. A composite material of polymer and carbon nanotubes that exhibits electric properties similar to the human brain is the foundation for the brain phantom. Additive manufacturing, more commonly known as 3D printing, is used to create shells for different brain regions based on the patient’s MRI. This shell becomes a mold for the polymer and carbon nanotube solution. Once the brain phantom takes shape within the mold, it is placed within a solution that dissolves the casing, leaving only the brain phantom behind. The conductive parts of the brain phantom are dark because of the carbon nanotubes and non-conductive parts are lighter in color. Electrodes are easily inserted into the brain phantom and provide feedback when an electromagnetic field from the TMS coil is applied. Adjustments to the strength, number of pulses of the field, and coil direction can then be made before applying the treatment to a patient. Having recently received a patent for the brain phantom, Hadimani and Wesley Lohr, a senior biomedical engineering undergraduate, formed Realistic Anatomical Model (RAM) Phantom. The pair have been awarded both the Commonwealth Commercialization Fund Award and the Commonwealth Cyber Initiative Dreams to Reality Incubator Grant. RAM Phantom’s goal is to market brain phantom technology to the growing neuromodulation market, which also includes transcranial direct current stimulation and deep brain stimulation. The company will also aid in the development of advanced brain models that more accurately simulate the properties of the human brain.

Ravi Hadimani profile photo
3 min. read