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Aston University and medicine manufacturer Catalent formed a Knowledge Transfer Partnership to identify more effective formulation additives The new selection matrix makes choosing the right additive quicker and the medicine development process shorter The project has been rated as ‘outstanding’ by Innovate UK A partnership between Aston University and contract medicine manufacturer Catalent has led to a faster process to identify the best ingredients for optimal medicine formulations, and has been rated as outstanding by Innovate UK. Catalent is a global leader in enabling pharma, biotechnology and consumer health partners to optimise product development, launch and full life-cycle supply for patients around the world. Its proprietary Zydis orally dissolving tablet (ODT) technology enables the absorption of drugs or active pharmaceutical ingredients (APIs) through the mouth tissues, which is much faster than absorption through the gut. However, many APIs have poor pre-gastric absorption and need to be combined with suitable excipients, or additives, to bind the active ingredients and speed up the process of dissolving and absorbing via the pre-gastric route. Identifying suitable excipients for the formulation is difficult, and so the Knowledge Transfer Partnership (KTP) between Aston University and Catalent was set up to develop a faster, more efficient approach. A KTP is a three-way collaboration between a business, an academic partner and a highly qualified researcher, known as a KTP associate. The UK-wide programme helps businesses to improve their competitiveness and productivity through the better use of knowledge, technology and skills. Aston University is a sector leading KTP provider, with 80% of its completed projects being graded as very good or outstanding by Innovate UK, the national body. The project was led by Aston University’s Afzal Mohammed, professor of pharmaceutics in the School of Pharmacy and associate dean (impact and knowledge exchange) for the College of Health and Life Sciences, who has expertise in the design and optimisation of orally dissolving tablet formulation. He was supported by other colleagues from Aston Pharmacy School including Dr Daniel Kirby, whose main area of research is the formulation of age-appropriate medicines for the extremes of life, Dr Affiong Iyire, who has research expertise in mucosal drug delivery, and Dr Raj Badhan, who is a pharmacokinetics expert with research interests in analytical approaches to predict oral drug absorption. Dr Ruba Bnyan, who has a master’s degree and a PhD in pharmaceutical drug formulation, as well as experience in cell-based models, was the KTP associate for the project. The KTP partners developed a selection matrix, whereby, based on the API properties, Catalent formulation scientists can quickly identify excipients that will improve the absorption of the drug through the mouth. Adopting this novel tool allows for quicker and more efficient drug development and has the potential to increase the number of Zydis ODT candidates in the pipeline for future development. Desmond Wong, product development supervisor at Catalent, said: “This project has exceeded our initial expectations and has the potential to accelerate product development for our clients. Our strong relationship with the Aston University team on this KTP project highlights the transformative potential of collaborative research and its impact on pharmaceutical innovation.” Professor Mohammed said: “This has been a very successful project, which has been rated as ‘outstanding’ by Innovate UK. We plan to put it forward for a KTP award and are looking forward to continuing working with Catalent on our next KTP project.” For more information on the KTP visit the webpage.
Tackling Tik Tok - Our expert explains what the problem is and what's next for the Chinese owned app
TikTok is one of the most popular social media sites in the world. In the United States, more than 170 million people and businesses use the app on a regular basis. Now, the federal government has taken the first step in banning the China-based app unless the ownership group, ByteDance, sells TikTok. The House of Representatives passed a bipartisan bill in support of the ban, and now it awaits Congress to act. President Joe Biden has indicated he would sign the bill banning TikTok unless it’s sold, but whether it reaches his desk remains to be seen. This stems from the fear that China uses user information to their advantage. According to Lance Hunter, PhD, associate professor of political science in Pamplin College of Arts, Humanities and Social Sciences, the concern is well deserved. “Even if it’s a privately-owned enterprise, China can still control it, they can still manipulate it to some degree as if it was a state -owned enterprise,” said Hunter. Hunter’s research focuses on how informational warfare attacks influence politics worldwide. He said the algorithm TikTok uses can play a major role in informational warfare on two fronts. “One, it’s the data gathering, and that can be used for micro targeting because basically what TikTok can do is collect the data and provide information as to what certain individuals respond to an this is exactly how you can persuade them.” “Also, there is empirical evidence that China has used TikTok before to try to influence elections to some degree. One example in the 2022 midterm elections in which some candidates from both parties were targeted by TikTok accounts that were controlled by a propaganda agency operating within the Chinese government.” Hunter added the TikTok algorithm is more advanced than some other social media platforms and more effective in knowing what people like and why they like it. With so many AI-generated posts, it can be difficult for the consumer to decipher what is legitimate, and what isn’t. There are some red flags for people to be on the lookout for. “One thing the average person can do is be very wary of what you’re seeing and ask yourself does this seem legitimate?” he added. “If everyone is saying the exact same thing, that’s a tell sometimes. Also, where does this information originate from, and what are the timestamps on the posts? Something else is to look at the individual who made the post. Who are these people and who’s following them? You may be able to see if they are legitimate accounts.” While China, and Russia for that matter, are trying to influence people in several ways, Hunter said they are also trying to cause division among the American people. “They do want to influence elections at times, absolutely. But one of their other goals, and sometimes even more predominant goals for them, is to increase division, increase polarization, and that’s a great way to do that,” Hunter said. “Even if you have a temporary reaction, you’ve increased that division which could have longer term effects.” Are you covering this important and ongoing story? Then let us help with your stories and questions. Lance Hunter is an assistant professor of political science with a background in international relations. His research focuses on how terrorist attacks influence politics in democratic countries and how political decisions within countries affect conflicts worldwide. He is available to speak with media about this important topic - simply click on his icon to arrange an interview today.
The Fed’s Interest Rate Decision Due Today: Is Inflation Creeping Back Up? | Media Advisory
Recent economic indicators suggest a worrying trend: inflation may be on the rise again. This media alert calls on journalists to investigate the underlying causes of this potential uptick, its implications for consumers, businesses, and policymakers, and the measures being taken to mitigate its impact. The discussion will span from the basics of inflationary pressure to the real-world effects on the cost of living and economic stability. Key areas of interest include: Drivers of Inflation: Identifying the economic factors contributing to the increase. Impact on the Average Consumer: How rising prices affect daily life and purchasing power. Government and Central Bank Responses: Policies and actions to curb inflation and protect the economy. Global Inflation Trends: Comparing the situation with inflationary trends in other countries. Investor Sentiment and Market Reactions: The financial markets' response to inflation fears. Long-Term Economic Outlook: Projections for the economy in light of potential inflationary pressures. For journalists seeking research or insights for their coverage on this topic, here is a select list of experts. Isabella Weber Associate Professor of Economics · University of Massachusetts Amherst John T. Harvey Professor · Texas Christian University Narayana Kocherlakota Lionel W. McKenzie Professor of Economics · University of Rochester James G. Devine Professor Emeritus of Economics · Loyola Marymount University To search our full list of experts visit www.expertfile.com Photo by engin akyurt
#Expert Q&A: NJIT’s Donghee Yvette Wohn Weighs the Pros and Cons of Kids Playing Esports
Donghee Yvette Wohn, an associate professor at New Jersey Institute of Technology and director of its Social Interaction Lab, focuses on human computer interaction, where she studies the characteristics and consequences of social interactions in online environments such as social media, live streaming, virtual worlds (metaverse) and esports. Here she explains the appeal of esports among children in particular and how their parents can assess what’s appropriate for them. How would you describe the current landscape of esports? Esports is an umbrella term that is used for competitive computer gaming that usually, but not always, happens in teams. However, similar to books or movies, the content of the games vastly differs. Some games are very violent, some are not. Some have very realistic graphics, some are very fantasy-like and playful. It is thus hard, especially as a parent, to make blanket decisions when it comes to esports, you may have to take things case by case. So, then how can parents assess what’s appropriate for their children? A quick online search into the nature of the game to see its description or even watching ten minutes of what the gameplay looks like on YouTube or Twitch — where many people upload videos of gameplay — will give parents a better idea of what the game is like without having to play it themselves. What about in terms of the other players? It may be useful to use physical sports or any other extracurricular activity as a mental reference when thinking of how to deal with certain issues. For example, soccer is a sport that is great for socializing and team building, but if one is placing a 10-year-old in a game with other adults, there would be a lot of extra things one would want to consider. Like any social activity, one would want to be mindful of who the child is playing with, how much they are playing and how they are playing. For example, are they being respectful? And what kind of language is being used during the game? What skills could esports and similar gaming help children develop? Based on research, the collaboration and communication skills required to play successfully are extremely high. Even though people do not associate computer games as being a physical skill, the dexterity and hand-eye coordination required to play well require a very high level of intellect and physical ability. Of course, not everyone plays that well, but it does indicate that esports is a little different than some games that are more “mindless” or “relaxing” in nature. What about social skills? It strengthens existing friendships and can also open up one’s world by conversing with strangers. My colleagues and I did a research study where we found a student living in a rural area where most people did not go to college who wanted to go college because he was inspired by the older college students he was playing with. Playing the game in supportive environments can be mentally and socially beneficial. What are the downsides? Like any social situation, there is always the possibility of people misbehaving. The types of harassment documented in gaming environments is so horrible, but the reality is that children are exposed to all types of horrible situations — both online and offline — and helping them navigate difficult situations can help build resilience for the future. What’s a common misconception among parents? The most important thing is to understand that whatever happens in esports is not to be dismissed as something that is “only online” or “not real.” The emotions that children experience in the virtual world are very much real. How much parental supervision is needed? Younger children’s brains have not yet developed self-constraint, so the parent should decide how much time should be spent playing games, what games are played and who they are played with. Older children — once they start understanding logic — should be encouraged to plan these things for themselves. Looking to know more? We can help. Yvette Wohn is available to discuss esports and kids with media. Simply click on her icon to arrange an interview.
Scandals, Health Scares and Sloppy Mistakes - Are the Royals in Turmoil? | Media Advisory
The British Royal Family finds itself at the center of an unprecedented media storm, grappling with a series of scandals, health scares, and public gaffes. This media alert invites journalists to delve into the causes and consequences of the recent tumult within the monarchy, examining its impact on public perception, the institution's future, and the broader implications for society's relationship with celebrity and authority. Key areas of focus include: Timeline of Recent Royal Controversies: A detailed look at the events causing widespread media attention. Public Perception and Royal Image: How these incidents have affected the public's view of the monarchy. The Role of the Media in Shaping Narratives: Analysis of media coverage and its impact on the situation. Mental Health and the Public Eye: The toll of public scrutiny on the Royals and lessons for broader society. The Future of the Monarchy: Speculations on potential changes within the institution and its place in modern Britain. Comparison with Historical Royal Scandals: Contextualizing current events within the long history of royal controversies. For journalists seeking research or insights for their coverage on this topic, here is a select list of experts. Carolyn Harris Historian, Author, Royal Commentator, Instructor, University of Toronto School of Continuing Studies Derek Arnold Senior Instructor, Communication | College of Liberal Arts and Sciences · Villanova University Ruth McClelland-Nugent, PhD Chair History, Anthropology & Philosophy · Augusta University To search our full list of experts visit www.expertfile.com Photo by Kutan Ural
MEDIA RELEASE: Voting for the 12th Annual CAA Worst Roads campaign is now open
Tired of swerving around potholes? Are you worried about your safety as a cyclist or pedestrian? Voting is now open for the annual CAA Worst Roads campaign, and CAA Manitoba is giving citizens the opportunity to voice their concerns about the bad roads in their communities. “Our research shows that 83 per cent of Manitobans vent their concerns about the state of roads either to their spouses, friends, co-workers or mechanics while very few (only three per cent) express their frustrations with local government officials and decision-makers,” says Ewald Friesen, manager government relations CAA Manitoba. “As we kick off another year of the CAA Worst Roads campaign, we are calling on all Manitobans to vote for their Worst Roads today and join the community of drivers, cyclists, transit riders and pedestrians committed to improving our roads and keeping our elected representatives accountable.” Those surveyed say they spent $962 on average to repair their vehicle. A survey conducted by CAA Manitoba found that 54 per cent of members in the province have experienced vehicle damage because of poor roads, with 70 per cent paying out of pocket to repair, only 16 per cent filing a claim with MPI and 14 per cent forgoing repairs altogether. “Either because of affordability or availability, many people are holding on to their cars a little longer these days; the last thing they should worry about is expensive repair bills on the already stretched family budget. While inflation rates have cooled, many of us are dealing with higher cost of living, making the investment in roads and supporting infrastructure more important than ever,” adds Friesen. The damage to a vehicle caused by a pothole can range from $500, with some fixes topping $2,000, depending on the make and model of the car. Those surveyed say they spent $962 on average to repair their vehicle. “We know that the campaign works and that decision-makers are listening. Since its inception in 2012, we have seen roads placed on the top ten list and come off with upgrades and repairs. The CAA Worst Roads campaign has been a vital platform for road users across Manitoba to nominate and vote for roads they believe are in urgent need of repair.” Read about CAA Manitoba’s Worst Roads Success Stories Manitobans can vote on issues ranging from congestion, potholes, poor road signs and the timing of traffic lights to pedestrian and cycling safety. Nominations for the Worst Roads campaign can be submitted online at www.caaworstroads.com from March 19 until April 12. Once the nominations are collected, CAA Manitoba will compile a list of the province's top 10 worst roads, which will be announced to the public. CAA conducted an online survey with 1,205 CAA Manitoba Members between January 10 to 19, 2024. Based on the sample size and the confidence level (95 per cent), the margin of error for this study was +/-3 per cent
#Expert Q&A: NJIT’s David Bader on AI, Data Science, Quantum Computing
Artificial intelligence, data science and the emerging field of quantum computing are among the hottest research topics in computing today. David Bader, a distinguished professor at New Jersey Institute of Technology’s Ying Wu College of Computing and the director of the university’s Institute for Data Science, offers his take on each. The Computer History Museum has recognized you for developing a Linux supercomputer using commodity hardware. Was that a life-shaping lesson? It was a venture into the unknown, leveraging the emerging potential of Linux and commodity hardware to build something that was both accessible and powerful. This experience taught me the importance of embracing risk and the value of resilience. There were technical hurdles, skepticism from peers and the daunting task of venturing beyond established norms. Also, the Linux supercomputer project was not just about the technology. It was about building a community around an idea. How do user-friendly AI systems like ChatGPT impact your work? It enriches the palette of methodologies and technologies at our disposal, enabling us to tackle more ambitious projects with greater efficiency and creativity. By integrating these AI systems into our research and educational programs, we're not just enhancing our ability to process and analyze data. We're also empowering students and researchers with the means to innovate and explore new horizons in data science without being hindered by the technical complexities that once acted as barriers. Some information workers fear that AI will make their careers obsolete. But tech progress can’t be stopped, so how should people adapt? By embracing these technologies, learning to work alongside them and leveraging their capabilities to enhance our own skill sets and productivity. Also, it's important to focus on the uniquely human skills that AI cannot replicate, such as creativity, emotional intelligence and critical thinking. By honing these abilities, workers can ensure they remain irreplaceable components of the workforce, capable of tasks that require a human touch — from complex decision-making to empathetic interactions with customers or clients. What should non-programmers learn about AI? It’s important to be aware of how AI decisions are made, the potential biases in AI systems and the ethical considerations of AI use. Additionally, developing data literacy is crucial, as it enables individuals to evaluate AI outputs and understand the importance of data quality and biases. A basic grasp of AI and machine learning concepts — even without programming skills — can demystify AI technologies and reveal their potential applications. Staying informed about AI advancements across various sectors can also inspire innovative ideas and foster interdisciplinary collaborations. There’s a sci-fi plot where computers get so smart that people lose control. The new class of user-friendly AI is making people excited but also nervous. Should we be afraid? While it’s natural to harbor concerns about the rapid progression of AI, allowing fear to dominate the discourse would be a disservice to the potential benefits these technologies can offer. Instead, this moment calls for proactive engagement with AI and an investment in understanding its inner workings, limitations and the ethical dilemmas it presents. By advocating for responsible AI development, emphasizing education and promoting transparency, we can foster an environment where AI serves as a tool for societal advancement. This approach ensures that we remain at the helm of AI's trajectory, steering it toward outcomes that uplift humanity rather than scenarios that fuel dystopian fears. What other emerging technologies excite you in their potential to transform computing? Quantum computing. This technology, with its potential to solve complex problems exponentially faster than classical computers, could revolutionize fields ranging from cryptography to drug discovery, climate modeling and beyond. Quantum computing's promise to tackle challenges currently beyond our reach, due to its fundamentally different approach to processing information, represents a leap forward in our computational capabilities. Its convergence with AI could lead to unprecedented advancements, making this era an incredibly thrilling time to be at the forefront of computing and data science. Looking to know more? We can help. David Bader is available to discuss AI, quantum computing and data science with media. Simply click on his icon to arrange an interview.
Oprah Hosts Primetime Special About Weight Loss Drugs on ABC | Media Advisory
Oprah Winfrey, a revered media mogul and advocate for health and wellness, is set to host a groundbreaking primetime special on ABC, focusing on the burgeoning field of weight loss drugs. The new special follows Winfrey’s exit from the board of weightwatchers, where she served for nearly a decade after acquiring a 10% stake in the company. This special promises to shed light on the science behind popular weight loss medications Ozempic, Mounjaro and Wegogy. As obesity rates continue to climb globally, the discussion around weight loss solutions becomes increasingly pertinent, touching on public health, self-image, and the pharmaceutical industry's role in shaping health standards. Key topics of interest include: Science and Effectiveness of Weight Loss Drugs: Exploring how these medications work and their success rates. Personal Stories of Transformation: Individuals' journeys with weight loss drugs, including challenges and triumphs. Ethical and Societal Implications: The debate over body image, health standards, and drug dependency. Regulatory Perspective and Safety: How these drugs are approved and monitored for public use. Impact on the Healthcare System: The potential effects on healthcare costs and accessibility. Cautions and Concerns: Are there serious side-effects and what are the risks related to taking these drugs? Future of Obesity Treatment: Innovations and next steps in treating obesity with pharmaceuticals. For journalists seeking research or insights for their coverage on this topic, here is a select list of experts. Rebecca Puhl, Ph.D. Professor of Human Development and Family Studies · University of Connecticut Professor Paul Gately Carnegie Professor of Exercise and Obesity and Co-Director of the Applied Centre for Obesity Research · Leeds Beckett University Rebecca Pearl Assistant Professor · University of Florida Jan D. Hirsch Founding Dean, School of Pharmacy and Pharmaceutical Sciences · UC Irvine Amy Gorin, Ph.D. Professor, Department of Psychological Sciences · University of Connecticut James Lenhard, Jr., M.D., FACE, FACEP Medical Director · ChristianaCare To search our full list of experts visit www.expertfile.com. Photo by Total Shape
Empowering Black and Latinx Boys in Their Postsecondary Journeys: The Role of School Communities
In a new study published in the American Educational Research Journal, Roderick L. Carey, assistant professor in the University of Delaware's College of Education and Human Development, offers a rich, ethnographic case study on how Black and Latinx boys imagine their postsecondary futures. With attention to the students’ first-person narratives about their school experiences and personal aspirations, Carey shows how their high school—a Mid-Atlantic college preparatory school in the United States—ultimately fails to understand and support their college, career and personal aspirations for life after graduation. “College is just one facet of a broader interconnected life that adolescents need support in imagining,” said Carey, who teaches and conducts research within CEHD’s Department of Human Development and Family Sciences. “Postsecondary future selves is a concept that folds together three pieces of that broader life—college, career and life condition, or ‘the 3Cs.’ By focusing on one, and ignoring the other two, educators miss the mark.” Carey is available to talk about this new study as well as the possible solutions to this issue. Her has been recently featured in Technical.ly and WHYY, an NPR affiliate. He can be contacted via his profile.
The U.S. House today passed a federal bill to ban TikTok and it now moves to the Senate. President Biden said he would sign a potential bill that bans the social media platform. Goizueta Business School Professor David Schweidel has done extensive research on the impact of social media. He says: The security and privacy issues around TikTok are only one part of the equation. User safety is another concern that all social media companies are now facing. He notes that the algorithms prioritize engagement, which could be showing people content that is harmful to them (mentally and/or physically). Background: TikTok is owned by ByteDance, a private Chinese company that claims all information gathered through the app is secure. Lawmakers do not agree and have plans to remove TikTok from the U.S. by September 30th unless ByteDance sells TikTok. The proposed bill would also put into place allowance for the executive branch to prohibit access to an app owned by a foreign adversary that could impact national security. Expert Source: David A. Schweidel, Professor of Marketing, Goizueta Business School at Emory University Bio - https://goizueta.emory.edu/faculty/profiles/david-schweidel To connect with David to arrange an interview - simply click his icon now.
