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Aston University research centre to focus on using AI to improve lives
• New centre specifically focuses on using AI to improve society • Current research is designed to improve transport, health and industry • “There have been a lot of reports focusing on the negative use of AI...this is why the centre is so important now.” Aston University researchers have marked the opening of a new centre which focuses on harnessing artificial intelligence (AI) to improve people’s lives. The Aston Centre for Artificial Intelligence Research and Application (ACAIRA) has been set up to become a West Midlands hub for the use of AI to benefit of society. Following its official opening, the academics leading it are looking to work with organisations and the public. Director Professor Anikó Ekárt said: “There have been a lot of reports focusing on the negative use of AI and subsequent fear of AI. This is why the centre is so important now, as we aim to achieve trustworthy, ethical and sustainable AI solutions for the future, by co-designing them with stakeholders.” Deputy director Dr Ulysses Bernardet added: “We work with local, national and international institutions from academia, industry, and the public sector, expanding Aston University’s external reach in AI research and application. “ACAIRA will benefit our students enormously by training them to become the next generation of AI practitioners and researchers equipped for future challenges.” The centre is already involved in various projects that use AI to solve some of society’s challenges. A collaboration with Legrand Care aims to extend and improve independent living conditions for older people by using AI to analyse data collected through home sensors which detect decline in wellbeing. This allows care professionals to change and improve individuals’ support plans whenever needed. A project with engineering firm Lanemark aims to reduce the carbon footprint of industrial gas burners by exploring new, more sustainable fuel mixes. Other projects include work with asbestos consultancy Thames Laboratories which will lead to reduced costs, emissions, enhanced productivity and improved resident satisfaction in social housing repairs and a partnership with transport safety consultancy Agilysis to produce an air quality prediction tool which uses live data to improve transport planning decisions. The centre is part of the University’s College of Engineering and Physical Sciences and its official launch took place on the University campus on 29 February. The event included a talk by the chair of West Midlands AI and Future Tech Forum, Dr Chris Meah. He introduced the vision for AI within the West Midlands and the importance of bringing together academics, industry and the public. Current research in sectors such as traffic management, social robotics, bioinformatics, health, and virtual humans was highlighted, followed by industry talks from companies Smart Transport Hub, Majestic, DRPG and Proximity Data Centres. The centre’s academics work closely with West Midlands AI and Future Tech Forum and host the regular BrumAI Meetup. About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
The Implications of the Collapse of Baltimore's Key Bridge: Insights from a Civil Engineer
The early morning collapse of Baltimore's Francis Scott Key Bridge is leaving experts and area residents alike in disbelief. Michael Chajes, a professor in the civil and environmental engineering department at the University of Delaware, is the go to person to speak on what happened and what this means for the future of this bridge. Chajes's expertise includes forensic engineering, specifically unearthing the root causes of engineering failures, such as bridge collapses. He has participated in the evaluation and testing of numerous major bridges and structures including the Brooklyn-Queens Expressway, Ben Franklin Bridge, Chesapeake City Bridge, Lock Gates on the Erie Canal and several historic trusses and polymer composite bridges. He is also the former Delaware Engineer of the Year. He is a civil engineer and has been speaking to the likes of CNN today about this bridge collapse. He is available and ready to chat if you'd like to connect with him. Chajes has been speaking with networks like CNN about the bridge collapse and is available for comment. He can be reached by clicking his "View Profile" button.
How Vulnerable Are America’s Water Systems to Outside Attack? | Media Advisory
The security of America's water systems is an issue of national importance, touching on the well-being and safety of millions. This topic gains urgency as it ties into broader concerns about infrastructure vulnerability, cyber-terrorism, and the readiness of public utilities to handle emerging threats. In light of recent breaches and heightened geopolitical tensions, the resilience of these essential systems is not just a matter of public safety but also of national security. Exploring this issue offers insights into: Cybersecurity measures for water supply systems The impact of climate change on water system resilience Federal and state responses to infrastructure threats Public health implications of water system breaches The role of technology in safeguarding against attacks Connect with an Expert about the Security of America's Water Systems For journalists seeking research or insights for their coverage about the Security of America's Water Systems, here is a select list of experts from our database. To search our full list of experts, visit www.expertfile.com Seth Hamman Director, Center for the Advancement of Cybersecurity and Associate Professor of Cyber Operations and Computer Science - Cedarville University David Bader Distinguished Professor, Data Science · New Jersey Institute of Technology Vladlena Benson Professor of Cybersecurity Management · Aston University William Hatcher Chair of the Department of Social Sciences · Augusta University TJ O’Connor, LTC (Ret.) Assistant Professor, Cybersecurity Program Chair | Computer Engineering and Sciences · Florida Tech Photo by: Adi Goldstein
Aston University to train the UK’s next generation of decarbonisation experts
Consortium led by the University is to receive almost £11 million to open doctoral training centre Will focus on use of biomass to replace fossil fuels and removal of CO2 “…part of the UK’s biggest-ever investment in engineering and physical sciences doctoral skills”. Aston University is to train the next generation of scientists tasked to remove greenhouse gases from the environment. A consortium led by the University is to receive almost £11 million to open a doctoral training centre which will focus on leading the UK towards net zero. The centre, based at Aston University, will bring together world-leading research expertise and facilities from the University of Nottingham, Queens University Belfast and the University of Warwick and more than 25 industrial partners. The funding has been announced by the UK science, innovation and technology secretary Michelle Donelan. The centre is to receive almost £8 million of government money while the remainder will be made up through match funding and support from industry and the four universities. The government has described it as part of the UK’s biggest-ever investment in engineering and physical sciences doctoral skills, totalling more than £1 billion. The Aston University centre will focus on the use of biomass to replace fossil fuels and removal (or capture) of CO2 from the atmosphere, with the potential to create new sources of fuels and chemicals. Integration of these two areas will lead to significant cost and energy savings. Called NET2Zero, the centre will train PhD students across the full range of engineered greenhouse gas removal techniques including direct air capture, CO2 utilisation (including chemical and material synthesis), biomass to energy with carbon capture and storage, and biochar. The students will work in the centre’s laboratories exploring the conversion of feedstock into alternative energy, improving conversion processes and measuring how the new technologies will impact the economy. Supported by a range of relevant industrial, academic and policy partners the centre will equip students to develop the broad range of skills essential for future leaders in decarbonisation. NET2Zero will be led by Professor Patricia Thornley, director of Aston University’s Energy and Bioproducts Research Institute (EBRI). She said: “I am delighted that this centre for doctoral training has been funded. The climate emergency is so stark that we can no longer rely on demand reduction and renewables to meet our decarbonisation targets. “If we are to have greenhouse gas removal options ready in time to be usefully deployed, we need to start now to expand our knowledge and explore the reality of how these can be deployed. This partnership of four leading UK universities with key industrial and policy partners will significantly augment the UK’s ability to deliver on its climate ambitions.” “We are absolutely delighted to be working with our partners to deliver this unique and exciting programme to train the technology leaders of the future. Our students will deliver research outcomes that are urgently needed and only made possible by combining the expertise and resources of all the centre’s academic and industry partners.” Science and technology secretary, Michelle Donelan, said: “As innovators across the world break new ground faster than ever, it is vital that government, business and academia invests in ambitious UK talent, giving them the tools to pioneer new discoveries that benefit all our lives while creating new jobs and growing the economy. “By targeting critical technologies including artificial intelligence and future telecoms, we are supporting world class universities across the UK to build the skills base we need to unleash the potential of future tech and maintain our country’s reputation as a hub of cutting-edge research and development.” Centres for doctoral training have a significant reputation in training future UK academics, industrialists and innovators who have gone on to develop the latest technologies. The University of Nottingham’s Dr Eleanor Binner said: “We are absolutely delighted to be working with our partners to deliver this unique and exciting programme to train the technology leaders of the future. Our students will deliver research outcomes that are urgently needed and only made possible by combining the expertise and resources of all the Centre’s academic and industry partners.” Her colleague Professor Hao Liu added: “We look forward to providing our best support to the NET2Zero CDT, including using our past and existing successful experience in leading other centres, to make this an exemplar.” Overall, there will be 65 new Engineering and Physical Sciences Research Council (EPSRC) centres for doctoral training which will support leading research in areas of national importance including the critical technologies AI, quantum technologies, semiconductors, telecoms and engineering biology. The funding is from a combination of £500 million from UK Research and Innovation and the Ministry of Defence, plus a further £590 million from universities and business partners. Notes to Editors EPSRC and BBSRC Centre for Doctoral Training in Negative Emission Technologies for Net Zero (NET2ZERO) Led by: Professor Patricia Thornley, Aston University The Engineering and Physical Sciences Research Council (EPSRC) is the main funding body for engineering and physical sciences research in the UK. Our portfolio covers a vast range of fields from digital technologies to clean energy, manufacturing to mathematics, advanced materials to chemistry. EPSRC invests in world-leading research and skills, advancing knowledge and delivering a sustainable, resilient and prosperous UK. We support new ideas and transformative technologies which are the foundations of innovation, improving our economy, environment and society. Working in partnership and co-investing with industry, we deliver against national and global priorities. The Biotechnology and Biological Sciences Research Council (BBSRC) invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond. Funded by government, BBSRC invested £451 million in world-class bioscience in 2019-20. We support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals. About Centres for Doctoral Training A CDT trains doctoral students with each centre focused on a specific theme or topic. Most CDTs will support five cohorts (a new cohort starting each academic year) with a cohort supporting an average of thirteen students. Fourteen of the centres will have four cohorts rather than five. EPSRC supports doctoral students through three training routes (Doctoral Training Partnerships, ICASE awards and CDTs), and in the last 30 years has supported over 50,000 doctoral students. About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Municipalities around the world have invested significant resources to develop connected smart cities that use the Internet of Things (IoT) to improve sustainability, safety and efficiency. With this increased demand for IoT experience, the VCU College of Engineering formed the OpenCyberCity testbed in 2022. The 1:12 scale model city provides a realistic, small-scale cityscape where students and researchers can experiment with new and existing smart city technology. Sherif Abdelwahed, Ph.D., electrical and computer engineering professor, is director of OpenCyberCity. He recently answered some questions about new developments within the testbed. The OpenCyberCity is a smart city testbed, but are there any real-life cities that one could call a smart city? Several real-life locales are considered smart cities due to their extensive use of technology and data-driven initiatives to optimize infrastructure and services. Dubai is one of the most notable. They have implemented smart transportation systems, buildings and artificial intelligence to transform the city’s operations and make them more efficient. Other reputable smart cities include Singapore and Seoul, which utilize smart energy management, smart transportation and comprehensive data analytics for improved urban planning and services. Seoul, in particular, has an initiative with smart grids and connected street lights, which VCU Engineering’s own OpenCyberCity test bed is working to implement. How does the OpenCyberCity address privacy? With so much technology related to monitoring, how are individual citizens protected from these technologies? Privacy is a major concern for smart cities and it is one of the main research directions for VCU Engineering’s OpenCyberCity. We are developing several techniques to prevent unwanted surveillance of personal information. Sensitive data is protected by solid protocols and access restrictions that only allow authorized users to view the data. Our aim is to find a reasonable middle ground between technological progress and privacy rights, staying within legal and ethical bounds. Some techniques to address privacy concerns include: Data Anonymization: This makes it difficult to trace back information to individual identities. Within the testbed, we will evaluate how to protect individual privacy while maintaining data utility and assess the impact on data quality. Secure Data Storage and Transmission: Encrypt data to protect it from unauthorized access. In the smart city testbed, these access control mechanisms will be implemented within the testbed’s infrastructure. We will also test different data handling processes and access control models to determine their ability to safeguard sensitive data. Privacy Impact Assessments: Regularly evaluate potential privacy risks of new smart city projects in order to mitigate them and ensure the ethical handling of data by those with access. Policy and Regulation Development: Data and insights generated from OpenCyberCity experiments can inform the development of cybersecurity policies and regulations for smart cities. How is the College of Engineering’s OpenCyberCity test bed different from similar programs at other institutions? While other universities have similar smart-city-style programs, each has their own specialty. The VCU College of Engineering’s OpenCyberCity test bed focuses on real-world contexts, creating a physical space where new technologies, infrastructure, energy-efficient transportation and other smart city services can be tested in a controlled environment. Our lab monitors real-time data and develops smart buildings, smart hospitals and smart manufacturing buildings to enhance the city’s technologies. Recent additions to the OpenCyberCity allow for expanded research opportunities like: Advanced Manufacturing: Students can apply advanced manufacturing techniques in a controlled environment. They can also test new materials, processes and automation technologies to improve efficiency and product quality. Energy Efficiency Testing: Environmental engineers and sustainability experts can evaluate energy consumption patterns within the smart manufacturing unit to implement energy-saving measures and assess their impact on sustainability. Production Optimization: Manufacturers can use real-time data from the smart manufacturing unit to optimize production schedules, minimize downtime and reduce waste. Predictive maintenance algorithms also help prevent equipment breakdowns. Education and Training: Hands-on experience with state-of-the-art manufacturing technologies helps train the workforce of the future. Integration with Smart City Services: Data generated by the manufacturing unit can be integrated with smart city services. For example, production data can inform supply chain management and energy consumption data can contribute to overall city energy efficiency initiatives. How has the OpenCyberCity changed in the last year? Is the main focus still data security? What started with research examining, analyzing and evaluating the security of next-generation (NextG) applications, smart city operations and medical devices has expanded. Data security is now only one aspect of OpenCyberCity. Its scope has grown to encompass more expansive facets of cybersecurity like automation and data analytics in the domain of smart manufacturing systems. The implementation of a smart manufacturing system in 2023 is something students really enjoy. Thanks to the vendor we used, undergraduate students had the option to develop functionality for various features of the manufacturing plant. Graduate students were also able to research communications protocols and cybersecurity within the smart manufacturing system. What does the smart manufacturing system entail and what kind of work is occurring within that system? An automated system is there for students to work with. Robot arms, microcontrollers, conveyor belts, ramps, cameras and blocks to represent cargo form an environment that emulates a real manufacturing setting. We’re currently brainstorming an expansion of the smart manufacturing system in collaboration with the Commonwealth Cyber Initiative (CCI). We plan to set up two building models, one for manufacturing and one for distribution, linked by a sky bridge conveyor system that moves items between the locations. Students work to leverage convolutional neural networks that use images to facilitate machine learning. When paired with the advanced cameras, it forms a computer vision system that can accurately place blocks in a variety of lighting conditions, which can be a challenge for other systems. By having to optimize the communication protocols that command the smart manufacturing system’s robotic arms, students also get a sense for real-world constraints . The Raspberry Pi that functions as the controller for the system is limited in power, so finding efficiencies that also enable stability and precision with the arms is key. Is there an aspect of cybersecurity for these automated systems? Yes. Devices, sensors and communication networks integral to the IoT found in smart manufacturing systems and smart cities generate and share vast amounts of data. This makes them vulnerable to cybersecurity threats. Some of the issues we look to address include: Data Privacy: Smart systems collect and process vast amounts of data, including personal and sensitive information. Protecting this data from unauthorized access and breaches is a top priority. Device Vulnerabilities: Many IoT devices used in smart systems have limited computational resources and may not receive regular security updates, making them vulnerable to exploitation. Interconnectedness: The interconnected nature of smart city components increases the attack surface. A breach in one system can potentially compromise the entire network. Malware and Ransomware: Smart systems are susceptible to malware and ransomware attacks, which can disrupt services and extort organizations for financial gain. Insider Threats: Employees with malicious intent or negligence can pose significant risks to cybersecurity. Potential solutions to these problems include data encryption, frequent software updates, network segmentation with strict access controls, real-time intrusion detection (with automated responses to detected threats), strong user authentication methods, security training for users and the development of well-designed incident response plans.
New Aston University spin-out company will develop novel ways to treat non-healing wounds
EVolution Therapeutics (EVo) has been founded on the work of Professor Andrew Devitt into the causes of inflammatory disease A failure to control inflammation in the body, usually a natural defence mechanism, can cause chronic inflammation, such as non-healing wounds Non-healing wounds cost the NHS £5.6bn annually, so there is a vital need for new treatments. Aston University’s Professor Andrew Devitt, Dr Ivana Milic and Dr James Gavin have launched a new spin-out company to develop revolutionary treatments to treat chronic inflammation in patients. One of the most common inflammatory conditions is non-healing wounds, such as diabetic foot ulcers, which cost the NHS £5.6bn annually, the same cost as managing obesity. Such wounds are generally just dressed, but clinicians say there is a vital need for active wound treatments, rather than passive management. The spin-out, Evolution Therapeutics (EVo), will aim to create these vital active treatments. Inflammation in the human body helps to fight infection and repair damage following injury and occurs when the immune system floods the area with immune cells. Normally, this inflammation subsides as the damage heals, with the immune system signalling to the immune cells to leave. However, in some cases, the usual healing mechanism is not triggered and the inflammatory response is not turned off, leading to chronic inflammation and so-called inflammatory diseases. EVo is based on Professor Devitt’s work on dying cells in the body, known as apoptotic cells, and how they contribute to health. Dying cells release small, membrane-enclosed fragments called extracellular vesicles (EVs), which alert the immune system to the death of cells, and then trigger the body’s natural repair mechanism and remove the dead cells. It is estimated that 1m cells die every second. Professor Devitt and his team have identified the molecules within the EVs which control the healing process and are engineering new EVs loaded with novel healing enzymes, to drive the body’s repair responses to actively heal wounds. Much of the research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC) with additional support from the Dunhill Medical Trust. Professor Devitt, Dr Milic and Dr Gavin received Innovation-to-Commercialisation of University Research (ICURe) follow-on funding of £284,000 to develop the vesicle-based therapy with EVo. Most recently, in December 2023, Professor Devitt and Dr Milic were awarded £585,000 from the BBSRC Super Follow-on-Fund to develop engineered cells as a source of membrane vesicles carrying inflammation controlling cargo. The team, together with Professor Paul Topham, also received funding from the National Engineering Biology Programme (£237,000) to support polymer delivery systems for vesicles. EVo is one of the 12 projects being supported by SPARK The Midlands, a network which aims to bridge the gap between medical research discoveries of novel therapeutics, medical devices and diagnostics, and real-world clinical use. SPARK The Midlands is hosted at Aston University, supported by the West Midlands Health Tech Innovation Accelerator (WMHTIA), and was launched at an event on 31 January 2024. Professor Devitt, EVo chief technical officer, said: “Inflammation is the major driver of almost all disease with a huge contribution to those unwelcome consequences of ageing. We are now at a most exciting time in our science where we can harness all the learning from our research to develop targeted and active therapies for these chronic inflammatory conditions.” Dr Gavin, EVo CEO, said: “The chronic inflammation that results in non-healing wounds are a huge health burden to individuals affecting quality of life as we age but also to the economy. Our approach at EVo is to target the burden of non-healing wounds directly to provide completely novel approaches to wound care treatment. By developing a therapy which actively accelerates wound healing, we hope to drastically improve quality of life for patients, whilst reducing the high cost attached to long term treatment for healthcare systems worldwide.”
Aston University establishes Design Factory Birmingham as a global innovation hub for Midlands
• Birmingham becomes the latest city to join a global network of design and digital consultancies • Based at Aston University, expertise in areas such as 3D printing will be shared to boost the local economy • It will include a space named after the late Dame Margaret Weston, former director of the Science Museum. Birmingham has become the latest city to join a global network of design and digital consultancies set up to solve real world challenges through effective problem-solving. Design Factory Birmingham will be based at Aston University, one of just two hubs in the UK outside of London. The city officially joined the Design Factory Global Network on Wednesday 14 February and as a result Aston University will open the doors to its state-of-the-art facilities to other organisations. Shared understanding and common ways of working enable Design Factories in the network to collaborate efficiently across cultures, time zones and organisational boundaries fostering radical innovations. Businesses, industry partners, entrepreneurs, staff and students will be able to collaborate on projects that will involve technologies such as 3D printers and design software. The University will be sharing its expertise in artificial intelligence, additive manufacturing, data science and web, app and graphic design to boost the local economy. Currently there are 39 innovation hubs in 25 countries across five continents based in universities and research organisations. The Design Factory will include a space named after the late Dame Margaret Weston, former director of the Science Museum. Dame Margaret had studied electrical engineering at one of Aston University’s predecessor institutions and went on to be the first woman appointed to lead a national museum. She left a generous gift to Aston University in her will, which will be commemorated in the Birmingham Design Factory in honour of her engineering background. (l-r) Felipe Gárate, Professor Aleks Subic, Professor Stephen Garrett The Vice-Chancellor and Chief Executive of Aston University, Professor Aleks Subic said: “The Design Factory Birmingham is another key milestone in our ambition to be a leader in science, technology, and innovation, driving socio-economic transformation in our city and region. It is important to the Midlands because it will make a direct contribution to innovation led growth in partnership with industry and businesses. However, this is not only a local launch but also a global launch as Design Factory Birmingham is a global innovation hub, and an integral part of the Design Factory Global Network involving 39 innovation hubs around the world.” The head of the Design Factory Global Network Felipe Gárate from Aalto University in Helsinki, Finland attended the official launch in Birmingham. He said: “I am delighted to welcome Aston University as our latest member. “We are on a mission to create change in the world of learning and research through passion-based culture and effective problem-solving. “Shared understanding and common ways of working enable Design Factories in the network to collaborate efficiently across cultures, time zones and organisational boundaries fostering radical innovations.” The launch event was used to showcase design projects that are already running and companies attending were given the chance to meet placement students who could boost their existing expertise. Associate Pro-Vice-Chancellor and Deputy Head of the College of Engineering and Physical Sciences, Professor Tony Clarke said “This unique space on campus will bring together multi-disciplinary teams of hands-on innovators, collaborative thinkers and creators. “We will be delivering a wide range of services including software application development, product design, creating protypes using a variety of technologies including laser and water cutting, digital and design training courses, and helping companies obtain innovation grants for projects.” As a member of the global network the Birmingham Design Factory at Aston University will participate in two global design challenges - one run by McDonalds and the other run by the Ford Motor Company. ENDS Notes to Editors There are 39 Design Factory hubs around the world https://dfgn.org/ In the UK there are three; London, Birmingham and Manchester. About Aston University For over a century, Aston University’s enduring purpose has been to make our world a better place through education, research and innovation, by enabling our students to succeed in work and life, and by supporting our communities to thrive economically, socially and culturally. Aston University’s history has been intertwined with the history of Birmingham, a remarkable city that once was the heartland of the Industrial Revolution and the manufacturing powerhouse of the world. Born out of the First Industrial Revolution, Aston University has a proud and distinct heritage dating back to our formation as the School of Metallurgy in 1875, the first UK College of Technology in 1951, gaining university status by Royal Charter in 1966, and becoming The Guardian University of the Year in 2020. Building on our outstanding past, we are now defining our place and role in the Fourth Industrial Revolution (and beyond) within a rapidly changing world. For media inquiries in relation to this release, contact Nicola Jones, Press and Communications Manager, on (+44) 7825 342091 or email: n.jones6@aston.ac.uk
Image shows how tiny water channels control how water enters and exits cells through their membranes The Aston Institute for Membrane Excellence (AIME) will be set up with a £10m grant from Research England AIME will be led by Professor Roslyn Bill from Biosciences and Professor Paul Topham from Chemical Engineering and Applied Chemistry The globally unique institute will use biomimetic polymer membranes for applications such as water purification and drug development Aston University will establish the Aston Institute for Membrane Excellence (AIME), a globally unique, cross-disciplinary institute to develop novel biomimetic membranes, after receiving a major grant of £10m from Research England. AIME will be led by Professor Roslyn Bill, from the School of Biosciences, with co-lead Professor Paul Topham from the department of Chemical Engineering and Applied Chemistry (CEAC). Membranes, both biological and synthetic, are hugely important in many sectors. For example, the world’s top ten selling human medicines all target proteins in biological membranes, while synthetic polymer membranes are used in the US$100bn/year water purification industry. The team behind AIME believes that the full potential of membranes will only be realised by an interdisciplinary group spanning biology, physics and chemistry that can investigate membranes holistically. Professor Bill, a European Research Council (ERC) Advanced grantee leads Aston Membrane Proteins and Lipids (AMPL) research centre of excellence that studies the structure and function of membrane proteins and associated lipids. Professor Topham leads Aston Polymer Research Group (APRG), which investigates the nanoscale behaviour of block copolymers (a type of polymer with a structure made of more than one type of polymer molecule) and polymer technologies for membranes. AMPL and APRG have already begun collaborative research and AIME will bring together the complementary expertise of both research clusters into one institute. AIME will initially comprise the eight researchers from AMPL and APRG. Alongside the co-leads Professor Bill and Professor Topham, will be Dr Alan Goddard, Professor Andrew Devitt, Professor Corinne Spickett, Dr Alice Rothnie, Dr Matt Derry and Dr Alfred Fernandez. It plans to recruit three further academics, six tenure-track research fellows, three postdoctoral research assistants (PDRAs), six PhD students, a research technician and a business development manager. Importantly, AIME will work with many existing Aston University colleagues to build a comprehensive research community focused on all aspects of membrane science. The new AIME team will focus on the development of bioinspired, highly selective polymer structures for applications in water purification and waste remediation, nanoparticles loaded with therapeutic molecules to treat disorders ranging from chronic wounds to neurological injuries, and the purification of individual membrane proteins with polymers to study them as drug targets. The vision is for AIME to become a ‘one-stop shop’ for interdisciplinary, translational membrane research through its facilities access and expertise, ideally located in the heart of the country. Professor Bill said: “The creation of AIME is ground-breaking. Together with Aston’s investment, E3 funding will deliver a step-change in scale and the rate at which we can grow capacity. We will address intractable scientific challenges in health, disease, and biotechnology, combining our world-class expertise in polymer chemistry and membrane biology to study membranes holistically. The excellence of our science, alongside recent growth in collaborative successes means we have a unique opportunity to deliver AIME’s ambitious and inclusive vision.” Professor Topham said: “We are really excited by this fantastic opportunity to work more closely with our expert colleagues in Biosciences to create advanced technology to address real world problems. From our side, we are interested in molecular engineering, where we control the molecular structure of new materials to manipulate their properties to do the things that we want! Moreover, we are passionate about a fully sustainable future for our planet, and this investment will enable us to develop technological solutions in a sustainable or ‘green’ way.” Professor Aleks Subic, Vice-Chancellor and Chief Executive of Aston University, says: “Our new Aston Institute for Membrane Excellence (AIME) will be a regional, national, and international research leader in membrane science, driving game-changing research and innovation that will produce a pipeline of high-quality research outcomes leading to socioeconomic impact, develop future global research leaders, create advanced tech spinout companies and high value-added jobs for Birmingham and the West Midlands region. Its establishment aligns perfectly with our 2030 strategy that positions Aston University as a leading university of science, technology and enterprise.” Steven Heales, Policy Manager (Innovation) at the West Midlands Combined Authority, said: “WMCA is delighted to see Research England back the Aston Institute for Membrane Excellence. This will enable Aston University’s excellent academics and research community to work closely with businesses to make advances in membrane technology and applications. “In 2023 the West Midlands Combined Authority agreed a Deeper Devolution Trailblazer Deal with Government, which included a new strategic innovation partnership with Government. Projects like AIME are exactly the kind of impact we expect this new partnership to generate, so watch this space.” Lisa Smith, chief executive of Midlands Mindforge, the patient capital investment company formed by eight Midlands research-intensive universities including Aston University, said: “This grant is an important vote of confidence in the Midlands scientific R&D ecosystem. AIME will play an important role in the future research of pioneering breakthroughs in membrane science and enable the world-leading research team at Aston University to develop solutions to real world problems. We look forward to closely working with the Institute and nurturing best-in-field research being undertaken at Aston out of the lab and into the wider society so it can make a positive impact”. Rob Valentine, regional director of Bruntwood SciTech, the UK’s leading developer of city-wide innovation ecosystems and specialist environments and a strategic partner in Birmingham Innovation Quarter, said: "As a proud supporter of the Aston Institute for Membrane Excellence (AIME), I am thrilled at the launch of this groundbreaking initiative. AIME exemplifies Aston University's commitment to advancing cutting-edge interdisciplinary research and further raises the profile of the region’s exemplary research capabilities and sector specialisms. AIME's vision of becoming a 'one-stop shop' for translational membrane research, strategically located at the heart of the country, aligns perfectly with our strategy at Bruntwood SciTech. We are committed to working with partners, including Aston University, to develop a globally significant innovation district at the heart of the UK where the brightest minds and most inspiring spaces will foster tomorrow’s innovation.” Membrane research at Aston University has also recently received two other grants. In November 2023, Professor Bill received £196,648 from the Biotechnology and Biological Sciences Research Council’s Pioneer Awards Scheme to understand how tiny membrane water channels in brain cells keep brains healthy. In December 2023, a team led by AIME team-member Dr Derry received £165,999 from the Engineering and Physical Sciences Research Council to develop biomimetic membranes for water purification. For more information about AIME, visit the webpage.
Aston University scientists to tackle challenges of converting rice straw into biofuels Researchers to examine issues that hinder conversion into an alternative fuel Will help protect global food security, minimise CO2 emissions and decrease farmland needed for growing energy crops. Aston University scientists are to tackle some of the challenges of how to make inedible rice straw into the next generation of biofuels. In recent years, biofuels and biobased chemicals have been blended with petrol to create a more sustainable alternative. The Aston University researchers are to examine issues that currently hinder the conversion of rice straw into an alternative fuel. Currently the production of biofuels mainly relies on sugar crops such as sugarcane and sugar beet, which raises major concern about the competition between growing crops for food or fuel. However plant dry matter such as rice straw is seen as a better alternative to current crops because it doesn’t affect food security. Rice straw is often treated as an agricultural waste by-product and is removed by burning in the field. Farmers burn straw to prepare to plough and sow rice credit: S.Narongrit99 The research is being led by Dr Alfred Fernandez-Castane, senior lecturer in biochemical engineering and principal investigator at the Energy and Bioproducts Research Institute (EBRI) at Aston University, alongside a Marie Curie fellow, Dr Longinus Igbojionu. Their two-year project, An integrated approach to ethanol production from rice straw via microwave-assisted deep eutectic solvent pretreatment and sequential cultivation using Candida tropicalis and Saccharomyces cerevisiae, will explore cleaner and cost effective methods to extract rice straw’s energy-containing molecules. Dr Alfred Fernandez-Castane said: “The problems envisaged with the conversion of rice straw to ethanol can be categorised into four main challenges and resolving each challenge will lead to a major advance on the current state of the art. “The first is to develop pre-treatment conditions which will break down complex polymers thereby allowing the removal of lignin. “The next is to investigate novel biomass pre-treatment technologies combining green solvents and microwaves and how different methods affect morphology, structure and crystallinity of biomass. The next is to develop novel biotrasnformations using the yeasts Candida tropicalis and Saccharomyces cerevisiae to convert sugars into ethanol efficiently. “These three challenges will lead to the fourth scientific challenge which is to make the process sustainable and scalable, such as recycling the wastewater created and even the possibility of using the by-product of yeast for animal feeds.” The team believes that the research will help contribute to combating global warming and decreasing avoidable deaths by protecting global food security, minimising CO2 emissions by reducing the burning of straw and decreasing the farmland needed for growing energy crops. The research will end in November 2025.
• Contaminated water is responsible for around 500,000 deaths a year • New transmembrane proteins will allow selective removal of single contaminant from water • Will use tiny transport channels around one million times smaller than an ant. Aston University scientists are to explore a more sustainable method of separating contaminants from water. The method will use exquisite molecular selectivity, which means that just a single chemical or molecular species will be able to pass through the membrane, allowing scientists to selectively remove a single contaminant from water. The World Health Organization estimates that microbiologically contaminated water is responsible for almost 500,000 deaths a year and current filtration technologies aren’t effective enough. The University has received a grant of £165,999 from the Engineering and Physical Sciences Research Council to research the use of bioinspired membranes to selectively remove contaminants from water, while using minimal energy. The membranes will be made from plastic but will have transmembrane proteins embedded within them, made possible thanks to new polymers developed by the University. The transmembrane proteins enable the selective removal of specific contaminants using transport channels measuring approximately 4-10 nanometres - around one million times smaller than an ant. The Aston University team led by Dr Matt Derry, lecturer in chemistry, will be developing bio-inspired membranes which selectively remove contaminants with minimal energy. Working with Dr Alan Goddard, reader in biochemistry at Aston University, the team’s design is based on solutions found in biological evolution and refinement which has occurred over millions of years. Dr Derry, who is based in the University’s College of Engineering and Physical Sciences. said: “Polluted water is a complex global socioeconomic issue that affects human and animal health, and greatly impacts industries such as agriculture and fishing, recreational activities and transport. “Current filtration technologies are ineffective and their manufacture often requires complex and expensive multi-step processes with high associated energy costs. “We are going to use advanced polymer synthesis to develop new bespoke polymers which will both extract transmembrane proteins and immobilise them within artificial separation membranes. “This will create water purification membranes which remove impurities with greater selectivity and specificity.” The new membrane technology developed in this project will advance and evolve membrane science. The platform materials and approaches used can be applied to other membrane filtration and water purification applications such as selective phosphate removal from agricultural wastewater. Dr Derry added: “We are hoping that the new membranes will lead to high-performance devices that can contribute to a circular economy. “The need for such new systems is recognised by the UN with Sustainable Development Goal six on clean water and sanitation.” The research will begin in April 2024 and will end in May 2026.