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Cancer Program Earns Reaccreditation From the Commission on Cancer

Report cited zero deficiencies and highlights leadership, innovative programs and strong research program The Commission on Cancer, a quality program of the American College of Surgeons, has granted three-year reaccreditation to the cancer program at ChristianaCare’s Helen F. Graham Cancer Center & Research Institute, one of the original National Cancer Institute Community Cancer Centers Program sites in the U.S. ChristianaCare has received accreditation since 1951. To earn accreditation, a cancer program must meet 34 quality care standards, be evaluated every three years through a survey process and maintain levels of excellence in the delivery of comprehensive patient-centered care. The Commission cited zero deficiencies during its site visit and in its final report. “Earning this prestigious accreditation with no deficiencies cited is a testament to the unparalleled expertise and quality of care our entire team at the Graham Cancer Center provides to our patients and community across the continuum of cancer care,” said Nicholas Petrelli, M.D., Bank of America Endowed Medical Director of the Helen F. Graham Cancer Center & Research Institute. “Patients in the communities we are privileged to serve can be assured of groundbreaking cancer treatments, innovative technology, state-of-the-art research, prevention, education and the most caring, dedicated team anywhere.” “Innovative programs that address community need” The Graham Cancer Center was recognized in the reaccreditation report for taking a multidisciplinary approach to treating cancer as a complex group of diseases that requires consultation among surgeons, medical and radiation oncologists, diagnostic radiologists, pathologists and other cancer specialists. This multidisciplinary partnership results in exceptional patient care. In its performance report, the Commission on Cancer praised the Graham Cancer Center’s leadership that has built a “culture of continual process improvement across all areas from prevention, screening, treatment and support for the patient.” It highlighted “innovative programs that address community need,” such as its on-site primary care practice and its Oncology Express Unit, which offers urgent care for patients with advanced disease. The report also stated that the “research trial offerings are a strong point.” Clinical trials test new drugs and combinations of treatments, as well as new techniques using surgery, radiation therapy, gene therapy, immunotherapy and biologics. ChristianaCare is among the national leaders in cancer clinical trials; patient enrollment rates into clinical trials at the Graham Cancer Center are at 29% which is seven times the national average. A national standard for accreditation The Commission on Cancer accreditation program provides the framework for the Graham Cancer Center to improve its quality of patient care through various cancer-related programs that focus on the full spectrum of cancer care including prevention, early diagnosis, cancer staging, optimal treatment, rehabilitation, life-long follow-up for recurrent disease and end-of-life care. When patients receive care at a Commission on Cancer-accredited facility, they also have access to information on clinical trials and new treatments, genetic counseling and patient-centered services including psycho-social support, a patient navigation process and a survivorship care plan that documents the care each patient receives and seeks to improve cancer survivors’ quality of life. Like all Commission on Cancer-accredited facilities, the Graham Cancer Center maintains a cancer registry and contributes data to the National Cancer Database, a joint program of the Commission on Cancer and American Cancer Society. This nationwide oncology outcomes database is the largest clinical disease registry in the world. Data on all types of cancer is tracked and analyzed through the database and used to explore trends in cancer care. Cancer centers, in turn, have access to information derived from this type of data analysis, which is used to create national, regional and state benchmark reports. These reports help facilities with their quality improvement efforts. Established in 1922 by the American College of Surgeons, the Commission on Cancer is a consortium of professional organizations dedicated to improving patient outcomes and quality of life for patients with cancer through standard-setting, prevention, research, education and the monitoring of comprehensive, quality care. There are currently more than 1,500 Commission on Cancer-accredited programs in the U.S. and Puerto Rico that diagnose and treat more than 70% of all patients newly diagnosed with cancer.

Aston University researchers collaborate with biotechnology start-up to develop drugs to tackle irreversible lung disease

• Researchers in the School of Biosciences partner with preclinical-stage biotechnology start-up company to develop drugs for fibrotic diseases • Professor Martin Griffin and team develop TG2 inhibitors to help treat a serious chronic lung disease called idiopathic pulmonary fibrosis. • Isterian Biotech is part of Cambrian BioPharma who have been working with Aston University since 2019. Aston University scientists are working with start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease. The focus of preclinical-stage biotechnology company Isterian Biotech is on developing novel drugs to stop or reverse the pathological accumulation of crosslinked proteins commonly observed in all major organs with age. As we age a chronic increase of crosslinked proteins occurs in the extracellular matrix (ECM), that surround, support, and give structure to the cells and tissues in the body. These crosslinked proteins are difficult for the body to degrade and over time can make organs stiff and dysfunctional, ultimately resulting in fibrosis. Reversing the accumulation of these pathological crosslinks will greatly contribute to reducing fibrosis. The start-up is working to develop small molecule inhibitors of transglutaminase 2 also known as TG2, which is one of the major crosslinking enzymes in the human body, that becomes more active during ageing - thus resulting in fibrotic diseases such as a type of lung disease known as idiopathic pulmonary fibrosis (IPF). Isterian President and Chairman of the Board, Georg C Terstappen, PhD said: "Isterian's strategy of combining rational drug design with efficient multiparametric profiling of synthesized small molecules has been both impressive and highly productive. Notably, for one of our highly potent and selective TG2 inhibitors, we have recently demonstrated efficacy in a mouse model of lung fibrosis for the first time. "Using this state-of-the-art approach to drug discovery combined with an impressive team gives us great confidence in the future of this novel company." IPF is a progressive, irreversible disease that is characterized by pathological crosslinking of extracellular matrix (ECM) proteins (a large network of proteins and other molecules that surround, support, and give structure to the cells and tissues in the body) leading to excessive deposition of collagen. This means that in IPF scar tissue or fibrosis builds up around the air sacs (alveoli) in the lungs and reduces the ability to transfer oxygen that is breathed into the blood, resulting in severe restriction of lung capacity and function. IPF is the most common form of pulmonary fibrosis. The disease affects between 200,000 and 300,000 people globally. Statistics from the charity Action for Pulmonary Fibrosis suggest there are about 30,000 people living with IPF in the UK with an estimated 6,000 new cases of the condition each year. The disease usually develops in people aged 70 and older and is more common in men. But it can occur in younger individuals, particularly if there is a family history of idiopathic pulmonary fibrosis. The company was founded by capitalizing on over 35 years of scientific research from the laboratory of Professor Martin Griffin and his team Dr Dan Rathbone and Dr Vivian Wang at Aston University. Their work with small molecule inhibitors selective for TG2 has demonstrated reduction of fibrosis in multiple organs in a number of animal models. In 2019, Aston University partnered with Cambrian to form Isterian Biotech with a mission to develop safe and effective TG2 inhibitors to treat Idiopathic pulmonary fibrosis (IPF), a devastating fibrotic disease of the lung. Professor Martin Griffin, Biosciences Research Group, Aston University said: “We are delighted to continue our work with Isterian researching how we can further develop TG2 inhibitors to help tackle this awful disease.” CEO of Cambrian BioPharma, James Peyer, commented: "As Cambrian continues on its mission to build medicines that will redefine healthcare in the 21st century, we are very thankful to find brilliant scientists such as Martin and his team that are willing to break the mold. Isterian and its work to reduce fibrosis are a perfect fit alongside the other pipeline companies our team has announced in 2022." The company's current pipeline includes an advanced preclinical-stage TG2 inhibitor for inhaled administration and several structurally unrelated back-up compounds for the treatment of IPF. For more information about the School of Biosciences at Aston University, please visit our website.

Our plastic brains: the wonderful world of wiring, waves and wandering – livestreamed public lecture

Aston Institute of Health and Neurodevelopment to host fourth in a series of livestreamed public lectures Lecture to explore Dr Stuart Greenhill's research into how the making and breaking of connections in our brains leads us to learn new skills and new information and how it affects neurological conditions such as epilepsy and schizophrenia The one-hour livestream will be followed by a Q&A and round table discussion. Aston Institute for Health and Neurodevelopment (IHN) will host its next livestreamed public lecture in the series Molecules to Minds with Dr Stuart Greenhill on Aston University’s digital channel Aston Originals on Thursday 23 February. In the lecture ‘Our plastic brains – the wonderful world of wiring, waves and wandering’ Dr Greenhill will explore through his research how the natural process of making and breaking connections in our brains leads us to learn new skills and new information. He will explain how this process changes in neurological conditions such as epilepsy and schizophrenia. Dr Stuart Greenhill, senior lecturer in neuroscience, said: “Many of us will have heard of the concept of synaptic plasticity, but it’s something that is often misunderstood and underestimated at the same time. “By gaining a better understanding of how our changing synapses shape the activity of our brains, we can make new insights into how we develop as children and young adults, and how this process can differ in certain neurological conditions. “I hope you can join me and hear more about how our brains are built and why a good night’s sleep is the best revision technique.” After the livestreamed lecture, Dr Greenhill and his host Professor Gavin Woodhall, co-director of IHN, will hold a 15-minute Q&A discussion, where audience members can ask questions. The livestream will take place at 16:00 – 17:00 GMT on Thursday 23 February on the Aston Originals YouTube channel. To register for this event please visit our Eventbrite page.

A.I. and Higher Education: The Rise of ChatGPT

ChatGPT. Maybe you’ve heard of it. Colleges and universities certainly have. It’s the chatbot that uses artificial intelligence (A.I.) technology to generate sentences based only on a brief prompt, writing anything from college-level papers to fanfiction. And as one might expect, the popular chatbot is taking the academic world by storm, raising questions about trust, academic integrity and even the future of college admissions. We turned to Seth Matthew Fishman, PhD, Assistant Dean of Curriculum and Assessment and associate teaching professor in the Department of Education and Counseling at Villanova University, to get his thoughts. Q: What makes ChatGPT different and why is it causing such a stir? Dr. Fishman: The use of chatbots is not a new debate in higher education. But ChatGPT and other similar free software certainly add a complex layer that we are only just now starting to have conversations about. There will be an ongoing debate about trust—Who wrote the material we are reading? To what extent if any, will it impact faculty members? There are also A.I. digital images, graphics, and design—To what extent do these programs impact our creative arts and design programs? I think these fields will mostly embrace A.I., though I can see issues of copyright infringement and artist control/attribution. Q: How are other chatbots being used in academic settings? DF: A.I. use already impacts higher education. If you ask any faculty member teaching a foreign language that requires a translation, they will have tales of work submitted by students who use online translation software. But benefits do exist for students and faculty regardless—we’re able to interact a bit more with others, reducing some language barriers. I expect we will see hundreds of articles about ChatGPT’s impact on education; there are likely several dissertations underway, and I expect to see ChatGPT and similar software cited in papers and likely even in authorship groups. Q: What will the impact of ChatGPT be on the college application and admissions process? DF: I think we’ll see conversations from college admissions professionals on the impact of ChatGPT on higher education admissions. For example, key components of college applications such as essays and writing samples may be impacted. And ChatGPT may also be used to write some rather good letters of recommendation. Q: What does the future hold? Will ChatGPT and similar A.I. programs maintain popularity? DF: I’m curious if A.I. will be used to generate employment cover letters. Additionally, many corporations already use A.I. to sift through candidate applications to narrow down their applicant pools. It may continue to transcend academia. I also expect to hear more from our philosophy and ethics experts to help us better understand the societal and educational implications of using A.I. in these ways. And these kinds of conversations will be had with our students to engage them as partners in the learning experience. We will probably generate new ideas and different perspectives from doing just that.

The effects of social media on domestic terrorism - Our experts have the answers

There is no question social media has an impact on today’s society. Worldwide there isn’t much research available with empirical evidence showing its effect. Lance Hunter, PhD, associate professor in Pamplin College of Arts, Humanities, and Social Sciences and the Masters of Arts in Intelligence and Security Studies program at Augusta University recently was part of two studies that show evidence linking social media to political violence including domestic terrorism and civil conflict. The studies included over 150 countries and covered the time frame 2000 to 2019. “One of the things we found very interesting is the amount of time that people spend on social media on average within each country per year. It really does matter in affecting the amount of domestic terrorism within countries,” said Hunter. While many are focused on what happens domestically, Hunter found that some countries have more social media usage as compared to the United States and have varying amounts of political violence within their countries. “When social media is dangerous is when it increases polarization. When it’s used to spread disinformation that disinformation can have a polarizing effect on citizens around the world, and that polarization is associated with political violence.” Even socio-economic factors can play a role in social media and its effect on people in a country. “Looking at our research and data and looking across democracies and non-democracies, different income levels of countries most developed, less developed, we see there is a noticeable effect that social media can really influence political violence, especially if it’s used for disinformation purposes.” He went on to add since their data ended in 2019, and there have been instances of violence in the U.S. since then, researchers may continue to speculate on the relationship between social media posts and the acts of domestic terrorism. Here's an excerpt from the journal's abstract in Behavioral Sciences of Terrorism and Political Aggression: Much qualitative research has drawn an association between social media and domestic terrorism, with the studies reaching different conclusions. However, few empirical studies have evaluated whether the surge in social media participation affects domestic terrorist events. Controlling for common explanations in the literature, we conduct a cross-national, time-series analysis of up to 151 countries from 2000 to 2019 to assess the impact of social media penetration on domestic terrorism. We find that greater social media penetration increases the likelihood of domestic terrorism in countries as it supports extremists’ ability to recruit, mobilize, and train terrorists. Using mediation analysis, we also find that greater social media penetration amplifies online and political polarization, increasing the likelihood of domestic terrorism events. Our work indicates the possible mechanisms linking social media and domestic terrorism and the need to develop and apply appropriate counterterrorism strategies to mitigate terrorist operations. “There is a noticeable effect that social media can really influence political violence, especially if it’s used for disinformation purposes. I think maybe it’s just something to think about going forward for governments and citizens regarding how we should approach social media because I think with any type of technology, it can be used for good or for evil.” While there are countries that try to limit certain social media platforms depending on what information is being transmitted, there will likely be ways around any restrictions put in place. “When you’re thinking overall regarding social media, and we’re thinking about communication over social media, is that individuals at times do have certain technologies that they can circumvent those controls at times. So it can be a cat and mouse game between the government and the citizens.” Dr. Lance Hunter is an assistant professor of political science with a background in international relations. His research focuses on how terrorist attacks influence politics in democratic countries and how political decisions within countries affect conflicts worldwide. Hunter is available to speak with media about this important topic - simply click on his icon to arrange an interview today.

The CRISPR Dilemma: A Road To Saving Lives Riddled with Roadblocks

The New York Times recently published an Op-Ed by Dr. Fyodor Urnov unpacking the incredible advancement and possibilities of CRISPR gene editing technology on human lives. It also addressed some of the roadblocks and challenges preventing this "not so new" technology from getting to the finish line of promise.  Dr. Eric Kmiec, the director of ChristianaCare's Gene Editing Institute, whose unparalleled research has led to over 18 patents that have advanced medical research, also shared his concern in a follow-up letter published by the New York Times about the many roadblocks standing in the way of life-saving opportunities with gene editing and CRISPR technology. Dr. Kmiec (above) in the lab "If we were able to safely and effectively approve a COVID vaccine in a year, we must do the same by pooling public and private funds and seek ways to speed science. Why can’t we support the most promising solutions to some of the longest running and most intractable of cancers or rare diseases?" The advancement of gene editing has not only been stalled by the outdated processes of medical reviews and policies, but many have introduced political and religious barriers. The idea of "playing God" or even Dr. Frankenstein when people hear the term "gene editing" raises ethical questions based on a lack of understanding. Some of these concerns are shared in this recent article in Futurism.  Ask one of the 100 people afflicted with a gene defect that could cost them their lives at age 7 and the perspective may be a little different. Nature makes mistakes, often imperfect, and impacted by the ever-changing landscape, impacted by external factors that are either known or unknown. Gene editing, simply put, can fix typos in genes that have experienced a glitch. As Dr. Kmiec puts it, "It allows us to correct mutations that are inbred in the genome, it's correcting nature's mistakes — and nature does make a bunch of mistakes." Whether gene editing fits into a belief system or is too otherworldly for some to grapple with, Dr. Kmiec asserts that speeding up the delays put onto science by process, politics or fear will result in saving lives, saving pain and advancing possibility. Dr. Urnov agrees, "Scientists owe them and their families honesty about the ‌‌chasm between a test tube in a lab and an IV line in a hospital. The greatest obstacles are not technical but legal, financial and organizational." Gene editing is a pioneering technology that can help humans, plants and animals alike. When it comes to putting it into action, at the very least, if science is there to help, everyone should have the choice to use it. 

Aston University computer scientist joins first UK-wide Young Academy

The new UK Young Academy is a network of early career researchers and professionals It has been established to tackle local and global issues Dr Alina Patelli is a senior lecturer in computer science at Aston University. Aston University is delighted to announce that Dr Alina Patelli, a senior lecturer in computer science in the College of Engineering and Physical Sciences, is among the first members of the new UK Young Academy – a network of early career researchers and professionals established to help tackle local and global issues and promote meaningful change. Dr Patelli specialises in evolutionary computation, specifically, genetic programming and its applications in smart cities, with a focus on traffic modelling and prediction. Her interests also include autonomic, knowledge-based systems, as well as self-adaptation and self-organisation in computing. As part of the first cohort of 67 members, announced on 10 January by UK and Ireland National Academies, Dr Patelli will have the opportunity to help shape the strategy and focus of this new organisation, based on areas that matter to them. Along with their fellow members from across academia, charity organisations and the private sector, they will have the chance to inform local and global policy discussions, galvanising their skills, knowledge, and experience to find innovative solutions to the challenges facing societies now and in the future. The UK Young Academy has been established as an interdisciplinary collaboration with prestigious national academies: the Academy of Medical Sciences, British Academy, Learned Society of Wales, Royal Academy of Engineering, Royal Irish Academy, Royal Society of Edinburgh, and the Royal Society. It joins the global initiative of Young Academies, with the UK Young Academy becoming the 50th to join the Young Academy movement. Dr Alina Patelli said: “I am anticipating the start of my service as a member of the UK Young Academy with great enthusiasm. I highly value the opportunity to collaborate with colleagues from across the spectrum of science and governance in order to make a significant impact on the UK’s approach to tackling national and international challenges. “The UK Young Academy is perfectly placed to substantively improve the life of human communities everywhere and I am honoured to contribute towards the achievement of that goal.” Professor Stephen Garrett, executive dean of the College of Engineering and Physical Sciences at Aston University, said: “I would like to congratulate Alina on being selected as one of the first members of the UK Young Academy. It is a fantastic achievement to have been selected to join this talented and diverse cohort. “I wish her every success and look forward to seeing the fruits of her work with the Young Academy.” The successful applicants officially took up their posts on 1 January 2023, and membership runs for five years. It is expected that the next call for applications will open in 2023.

Aston University appoints new pro-vice-chancellor and executive dean of business and social sciences

Professor Zoe Radnor has been appointed as Pro-Vice-Chancellor and Executive Dean of the College of Business and Social Sciences She has had a successful career in higher education for over 25 years Professor Radnor will be joining Aston University in Spring 2023. Aston University has appointed Professor Zoe Radnor as the new Pro-Vice-Chancellor and Executive Dean of the College of Business and Social Sciences. Professor Radnor will succeed Professor George Feiger, who will be standing down after 10 years of leadership of Aston Business School and the College of Business and Social Sciences. With a successful career in higher education spanning over 25 years, Professor Radnor will be joining Aston University from The University of Law (ULaw), where she is currently Provost and Deputy Vice-Chancellor, specifically focused on leading the diversification of the academic portfolio, including building an academic model for the provision of high quality, innovative teaching and thought leadership. In addition, she is leading the TEF submission at the institution Prior to her executive role at ULaw, she was Vice-President for Strategy and Planning; Equality, Diversity and Inclusion and Professor of Service Operations Management at City, University of London, leading the development of the University EDI strategy. In this role she also led the creation of the new enabling Civic Strategy and established the new institution-wide Change Support Unit. Before City, Professor Radnor was the founding Dean of the School of Business at the University of Leicester, and prior to that, as Associate Dean Teaching and Learning, she led the development of new curriculum offerings for the Loughborough University campus in London. Professor Zoe Radnor is a Fellow of the Academy of Social Sciences (FAcSS) and the British Academy of Management (FBAM). She is also a member of the Athena Swan Governance Committee for Advance HE. Her main research interests are in performance, process improvement and service value within public sector organisations. She has led research projects for a number of Government and healthcare organisations, evaluating the use of ‘lean’ and associated techniques and continues to maintain a strong ongoing research profile. Professor Aleks Subic, Vice-Chancellor and Chief Executive of Aston University, said: “I am looking forward to welcoming Professor Radnor to the Executive Team at what is a hugely exciting period of development for the University and to working with her as we shape our Aston University 2030 Strategy. Zoe brings significant leadership experience to the team and ambition in line with our bold vision. “I would also like to take this opportunity to acknowledge the significant contribution made by Professor George Feiger during his leadership of Aston Business School and the College of Business and Social Sciences over the last 10 years.” Professor Radnor said: “I am delighted to be joining such a prestigious and forward-thinking University and College. “The reputations of the College of Business and Social Sciences and of Aston University generally and the strategic vision of the new Vice-Chancellor and University leadership are what attracted me to this exciting role. I can’t wait to get started working with so many talented and innovative new colleagues.” Professor Radnor will be taking up her post in Spring 2023.

Aston University students take home two prizes from annual European Union simulation event

EuroSim is an annual international intercollegiate simulation of the European Union More than 150 students, from universities in North America and Europe, participate every year The Aston EuroSim Team was awarded best debater in two categories. Aston University’s EuroSim team has returned from this year’s event with two awards. The Aston EuroSim Team was awarded best debater in the European Parliament Committee on Employment and Social Affairs (EMPL) and best in special roles (media/journalist). EuroSim is an annual international intercollegiate simulation of the European Union (EU). The purpose of it is to provide a framework for a simulation of the EU decision-making on major current issues. More than 150 students, from 16 universities in North America and Europe, participate in the simulation. All students are assigned roles, including members of the European Parliament (MEPs), members of the European Commission, heads of government and national ministers. The purpose of this module is to educate students about the inner workings of the European Union in order to enhance the learning experience for students. This year it was hosted by the University of South Wales in Newport, the first time the event has been held in the UK. Dr Patrycja Rozbicka, a senior lecturer in politics and international relations who is the lead for Aston EuroSim and was European associate director for EuroSim experience (2019-2023), said: “Here at Aston University, the EuroSim module is one of the most innovative modules of the Aston Politics and International Relations Department’s undergraduate and MA programmes. Amin Hassan, a final year international relations and English language student at Aston University, who took part in EuroSim, said: “I would like to extend my gratitude to my team from Aston University, and special mentions to my lecturer Dr Patrycja Rozbicka and student director Chris Burden for organising and inviting us to this memorable trip. “Representing Max Orville (my alter ego), MEP and Renew Europe Group, I worked together with my party and committee members with shared interests and values to ensure that no one is left behind by the proposed Social Climate Fund, which has recently been approved in real life. “After three days packed with negotiations and meetings, we are pleased that the Social Climate Fund has been approved and we strongly believe that it will support vulnerable people, households, micro-enterprises and transport users at risk of facing higher costs as the bloc introduces new climate measures.” Chris Burden, European students director at EuroSim and PhD researcher at Aston University, said: “I had the greatest honour attending the EuroSim2023 meeting at the ICC Wales as the European student director and part of Team Aston. “The work that goes into this conference is unbelievable, and the students had a fantastic time debating and simulating questions surrounding social and climate action within Europe. “This Transatlantic conference is the highlight of any year. “Thank you to our fantastic team from Aston University who brought home the two awards for their efforts.” The next EuroSim will be held next year in Brockport, northern New York State, USA. If you want to read more about the Aston EuroSim, click here.

Aston University research to support SMEs and mid-sized companies to be ‘future ready’

‘Future readiness’ is defined as a set of capabilities and orientations that enable companies to thrive in the future Researchers say SMEs and mid-sized companies’ leadership should focus on bridging their resilience gap and exploiting their high level of agility The report found circular economy can combat environment and social impact without sacrificing economic performance. A new report from Aston University has highlighted opportunities for small and medium sized enterprises (SMEs) and mid-sized companies to develop strategies and pathways to increase their future readiness. The report defines future readiness as “a set of capabilities and orientations that enable companies to thrive in the future”. For SMEs and mid-sized businesses to be future-ready, they must be successful on the three pillars of long-term growth, societal impact and adaptive capacity. Experts say they must be able to generate lasting financial strength driven by innovative business models, products and/or services, to affect society positively in line with environmental, social and governance (ESG) goals and to develop high levels of resilience and agility, which enables them to bounce back in difficult times and to identify and seize opportunities as they emerge, creating disruption in business models for the future. The report aims to support leadership teams and the wider ecosystem in understanding how they can help increase the capacity for smaller companies to thrive and positively impact the economy and environment, as well as aid the recovery from the pandemic. Experts also say that circular economy adoption, where the ‘make, use and throw away’ supply chain is converted to ‘take, make, distribute, use and recycle’, in SMEs and mid-sized companies creates a win-win situation for every supply chain stakeholder through sustainability measures to achieve economic, environment and social performance. The World Economic Forum will use the insights generated in this report to further support SMEs and mid-sized companies in their future readiness journey. This will be done through the creation of additional resources, including the continuous development of the Forum’s self-assessment and benchmarking tool on future readiness, the creation of a platform for informal peer-to-peer learning between companies and meet ups with key experts. Prasanta Kumar Dey, professor in operations and information management at Aston Business School and lead author of the report, said: “The post-COVID-19 era is significantly more challenging than most people had initially hoped. Heightened geopolitical tensions, the energy crisis, supply chain disruptions, hyperinflation and extreme weather events are just a few of the difficulties that will make the next decade a demanding one. “SMEs and mid-sized companies’ leadership should try to focus on bridging their resilience gap and exploiting their high level of agility, afforded by their smaller size, as a competitive advantage. “Future readiness capability building should not be developed as ad-hoc initiatives but should be embedded into key corporate strategies and decision-making processes, ideally from the beginning, so that it becomes part of the fundamental building blocks of the company. “While smaller companies can go a long way in building their future readiness, it is important to recognise the direct and important impact that their wider policy environment has on their ability to thrive. It is therefore crucial for policymakers, investors and other stakeholders to do what is in their capabilities to contribute to building the future readiness of this segment of the economy. “One of the high-impact areas of intervention at the system levels revolves around digital trade and includes implementing targeted measures to harmonize and drive trade data interoperability across borders and supply chains. This would greatly contribute to making it easier for smaller companies to trade internationally.” You can find out more about the report findings here.