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Scientist’s cat, again, helps discover new virus

Pepper, the pet cat who made headlines last year for his role in the discovery of the first jeilongvirus found in the U.S., is at it again. This time, his hunting prowess contributed to the identification of a new strain of orthoreovirus. John Lednicky, Ph.D., Pepper’s owner and a University of Florida College of Public Health and Health Professions virologist, took Pepper’s catch — a dead Everglades short-tailed shrew — into the lab for testing as part of his ongoing work to understand transmission of the mule deerpox virus. Testing revealed the shrew had a previously unidentified strain of orthoreovirus. Viruses in this genus are known to infect humans, white-tailed deer, bats and other mammals. While orthoreoviruses’ effects on humans are not yet well understood, there have been rare reports of the virus being associated with cases of encephalitis, meningitis and gastroenteritis in children. “The bottom line is we need to pay attention to orthoreoviruses, and know how to rapidly detect them,” said Lednicky, a research professor in the PHHP Department of Environmental and Global Health and a member of UF’s Emerging Pathogens Institute. The UF team published the complete genomic coding sequences for the virus they named “Gainesville shrew mammalian orthoreovirus type 3 strain UF-1” in the journal Microbiology Resource Announcements. “There are many different mammalian orthoreoviruses and not enough is known about this recently identified virus to be concerned,” said the paper’s lead author Emily DeRuyter, a UF Ph.D. candidate in One Health. “Mammalian orthoreoviruses were originally considered to be ‘orphan’ viruses, present in mammals including humans, but not associated with diseases. More recently, they have been implicated in respiratory, central nervous system and gastrointestinal diseases.” The Lednicky lab’s jeilongvirus and orthoreovirus discoveries come on the heels of the team publishing their discovery of two other novel viruses found in farmed white-tailed deer. Given the propensity of viruses to constantly evolve, paired with the team’s sophisticated lab techniques, finding new viruses isn’t entirely surprising, Lednicky said. “I’m not the first one to say this, but essentially, if you look, you’ll find, and that’s why we keep finding all these new viruses,” Lednicky said. Like influenza virus, two different types of orthoreovirus can infect a host cell, causing the viruses’ genes to mix and match, in essence, creating a brand new virus, Lednicky said. In 2019, Lednicky and colleagues isolated the first orthoreovirus found in a deer. That strain’s genes were nearly identical to an orthoreovirus found in farmed mink in China and a deathly ill lion in Japan. How in the world, the scientific community wondered, could the same hybrid virus appear in a farmed deer in Florida and two species of carnivores across the globe? Some experts speculated that components of the animals’ feed could have come from the same manufacturer. With so many unanswered questions about orthoreoviruses and their modes of transmission, prevalence in human and animal hosts and just how sick they could make us, more research is needed, DeRuyter and Lednicky said. Next steps would include serology and immunology studies to understand the threat Gainesville shrew mammalian orthoreovirus type 3 strain UF-1 may hold for humans, wildlife and pets. For readers concerned about Pepper’s health, rest assured. He has shown no signs of illness from his outdoor adventures and will likely continue to contribute to scientific discovery through specimen collection.    “This was an opportunistic study,” Lednicky said. “If you come across a dead animal, why not test it instead of just burying it? There is a lot of information that can be gained.”

New Study Finds Most Patients Can Safely Continue Weight Loss and Diabetes Drugs Before Gynecologic Surgery

Most patients taking popular weight loss and diabetes medications such as Ozempic and Wegovy can safely continue them before gynecologic surgery, according to a new journal article from ChristianaCare published in Obstetrics & Gynecology. The review found that serious anesthesia risks linked to these drugs are uncommon for most patients and can usually be managed through individualized planning rather than stopping the medication. The paper is the first to take a focused look at glucagon-like peptide-1 receptor agonists, commonly called GLP-1 drugs, in gynecologic surgery. These medications were first approved to treat diabetes and are now widely used to support weight loss and metabolic health, which refers to how the body processes sugar and energy. “Our study shows that the evidence does not support routinely stopping these medications before surgery and that the actual risk is low for most patients,” said Michelle Pacis, M.D., MPH, senior author of the study and a minimally invasive gynecologic surgeon at ChristianaCare. Why these medications raised concerns GLP-1 drugs work in part by slowing how quickly the stomach empties. This helps patients feel full longer, but it also raises concerns for surgery. Doctors worry that food remaining in the stomach could increase the risk of aspiration, when stomach contents enter the lungs during anesthesia. Because of this, early recommendations often advised stopping GLP-1 medications before surgery. The ChristianaCare review found that this approach was largely based on caution rather than strong evidence. The authors reviewed data from multiple studies, including large patient groups, that examined outcomes in people taking GLP-1 drugs during procedures. While some studies showed higher amounts of stomach contents, aspiration events were rare and occurred at rates similar to patients who were not taking the medications. New guidance reflects a change in thinking Recent national guidance from several medical societies now recommends a more tailored approach. Most patients can continue GLP-1 medications before surgery. For patients with higher risk factors, such as significant stomach symptoms or known delayed digestion, simple precautions can reduce risk. These precautions may include a clear liquid diet for 24 hours before surgery or closer monitoring during anesthesia. A clear liquid diet includes fluids like water, broth and clear juices. “This shift recognizes both the benefits of these medications and the importance of patient-specific decision making,” Pacis said. Why this matters for gynecologic surgery Many gynecologic surgeries require patients to be positioned in ways that can affect breathing and circulation. At the same time, many patients needing these procedures also have obesity or diabetes, which can increase surgical risk. GLP-1 medications can improve blood sugar control and support weight loss, helping patients enter surgery in better overall health and enhance recovery. Stopping these drugs without a clear reason may work against those benefits. Practical steps to support patient safety The study outlines several strategies care teams can use when patients remain on GLP-1 medications. These include thoughtful anesthesia planning, careful monitoring of heart and lung function, and, in select cases, the use of ultrasound to check stomach contents before surgery. “The goal is not to ignore risk, but to manage it wisely,” Pacis said. “For many patients, continuing these medications supports safer surgery and better recovery.” The authors note that more research is needed, particularly studies focused specifically on gynecologic surgery. Still, the findings offer clarity for patients and clinicians navigating a rapidly changing area of care. “This review helps bring evidence and balance to an issue that has caused a lot of confusion,” Pacis said. “It supports keeping patients on therapies that benefit their health whenever it is safe to do so.”

Two Research Scientists at the Cawley Center for Translational Cancer Research Earn Top Honors at UD Biology Research Day

Two rising cancer researchers from ChristianaCare’s Cawley Center for Translational Cancer Research were recognized for outstanding scientific contributions at the University of Delaware’s Annual Biology Research Day Conference on January 30, 2026. The awards highlight the strength and impact of colorectal cancer research underway at the Cawley Center. Anh Nguyen, a third year Ph.D. student, received the conference’s first place poster award for his project, “FGF19/FGFR4 Axis: A Key Driver in Tumor Growth and Treatment Resistance in Colorectal Cancer.” His research explores a signaling pathway that may lead to new strategies for targeting treatment resistant disease. Molly Lausten, a fifth year Ph.D. student, earned third place for her presentation, “Investigating the role of miR 27a 3p in the WNT signaling pathway and chemoresistance in colorectal cancer stem cells.” Her work examines a key microRNA that may influence resistance to therapy, a major challenge in treating aggressive tumors. “These awards reflect far more than individual excellence,” said Bruce M. Boman, M.D., Ph.D., MSPH, FACP, senior scientist and director of Cancer Genetics at the Cawley Center. “They show the power of rigorous, curiosity driven science to move the field forward. Molly and Anh are tackling some of the hardest questions in colorectal cancer, and their success speaks to the innovative environment we are building at ChristianaCare. I could not be more proud of their achievement and their commitment to improving outcomes for patients.”

ExpertSpotlight: The Surprising (and Slightly Dark) History of Valentine’s Day

Valentine’s Day may now be synonymous with chocolates, flowers, and heart-shaped everything, but its origins are far more complex, blending ancient Roman traditions, Christian martyrdom, and medieval storytelling. What began as a mid-winter festival tied to fertility and renewal eventually evolved into a celebration of romantic love - one shaped as much by poets and pop culture as by saints and religious history. Ancient Roots: Before Romance, There Was Ritual Long before Valentine’s cards, ancient Romans celebrated Lupercalia, a mid-February festival focused on fertility, purification, and the coming of spring. The event included symbolic rituals meant to ward off evil spirits and promote health and fertility, far removed from today’s candlelit dinners. As Christianity spread through the Roman Empire, many pagan festivals were re-interpreted or replaced with Christian observances, laying the groundwork for what would become Valentine’s Day. Who Was Valentine, Anyway? There isn’t just one Valentine. Historical records point to multiple early Christian martyrs named Valentine, the most famous being Saint Valentine, executed in the 3rd century CE. One popular legend claims he secretly performed marriages for young couples despite a Roman ban, acts that ultimately led to his execution. While historians debate the accuracy of these stories, they helped cement Valentine’s association with love, sacrifice, and devotion. Love Enters the Story: Medieval Poets Change Everything Valentine’s Day as a romantic holiday didn’t truly take shape until the Middle Ages. English poet Geoffrey Chaucer is often credited with linking February 14 to romantic love in his poetry, helping popularize the idea that it was the day birds chose their mates. From there, the connection between Valentine’s Day and courtly love spread across Europe, especially among the nobility, eventually giving rise to handwritten love notes and tokens of affection. From Handwritten Notes to Hallmark By the 18th and 19th centuries, Valentine’s Day had become a popular occasion for exchanging cards, flowers, and gifts. The Industrial Revolution made printed cards widely available, transforming a once-elite tradition into a mass-market celebration. Today, Valentine’s Day is a global cultural phenomenon, equal parts romance, commerce, and tradition,  evolving to include friendships, self-love, and inclusive expressions of connection. It isn’t just about romance, it reflects how traditions evolve over time, absorbing layers of culture, religion, and storytelling. Understanding its history helps explain how societies redefine love, relationships, and celebration across generations. Our experts can help! Connect with more experts here: www.expertfile.com

What Time Should You Actually Turn Off Your Phone at Night?

Everyone’s heard you’re “not supposed to be on your phone before bed” but what does that actually mean in 2026? Most major sleep organizations now recommend putting devices away at least 30–60 minutes before bedtime to protect melatonin and help the brain wind down. The National Sleep Foundation and the American Academy of Sleep Medicine both advise turning off screens about an hour before bed; other experts say a 30–60 minute window is the minimum. (Advisory) Research on blue light shows that evening screen exposure suppresses melatonin and delays sleep, especially when you’re scrolling something stimulating. (Sutter Health) Psychotherapist Harshi Sritharan, MSW, RSW, who specializes in ADHD and digital dependency, puts it bluntly: “To ensure quality sleep and peak performance—whether in sports, work, or school—avoid using your phone after 11 p.m.” For teens and adults with ADHD or anxiety, she says, late-night doomscrolling is especially brutal: screens keep dopamine and stress high at exactly the time the nervous system should be powering down. Harshi says: "The quality of sleep determines your level of executive functioning the next day" She also makes an important distinction: if you are on a device in the evening, active use (choosing a show, talking to friends, looking up something specific) is less harmful than passive use: “Don’t do passive tech use — that doom scrolling, content just being thrown at you,” Sritharan says. “Be more active about your tech use.” That kind of passive feed is more likely to serve up emotionally intense content kids didn’t ask for and aren’t ready to process. You Don’t Need a Perfect Curfew to See Results The good news: the science suggests you don’t have to quit completely at night to feel a difference. A JAMA Network Open study on young adults found that reducing social media use for just one week — not going cold turkey — led to about a 24.8% drop in depression, 16.1% drop in anxiety and 14.5% improvement in insomnia symptoms. Offline.now founder Eli Singer argues that the real challenge is confidence, not willpower. Their data show 8 in 10 people want a healthier relationship with tech, but more than half feel too overwhelmed to know where to start. The platform’s behavior data also show that late afternoons and evenings are when phones dominate use and when people are actually most motivated to make changes. We have less in the tank at night, don't trust willpower to transition off. Have a system/routine of pre-decided of low-effort (potentially fun) activities to help the transition off phones. “We tell people: don’t start with a perfect 8 p.m. curfew,” Singer says. “Start with one realistic phone-off window — even 30 minutes before bed — and prove to yourself you can protect that. That first win matters more than an ideal schedule you’ll never keep.” A Simple, Science-Aligned Answer For most people, Offline.now’s experts land on a practical, high-compliance answer to the question “What time should I turn off my phone?” Aim to put your phone away 30–60 minutes before your target bedtime Make everything after that screen-free by default (books, stretching, music, talking, journaling) If you must be on a device late, keep it brief, low-drama and intentional — no infinite feeds, no emotionally loaded content It’s a small change, but in the context of a day where we’re already on screens for roughly 10 of our 16 waking hours, that last hour matters. Featured Experts Harshi Sritharan, MSW, RSW – Psychotherapist specializing in ADHD, anxiety, insomnia and digital dependency. She explains how late-night and early-morning phone use hijack dopamine, disrupt sleep and make it harder for kids and adults to function the next day. Eli Singer – Founder of Offline.now and author of Offline.now: A Practical Guide to Healthy Digital Balance. He speaks to the platform’s behavioral data on when people are most ready to change, and how 20-minute micro-experiments (like one phone-off window at night) build real confidence over time. Expert interviews can be arranged through the Offline.now media team.

How ACL injury derailed Lindsey Vonn's heroic return to Olympic competition

An ACL rupture couldn't keep skiier Lindsey Vonn off the slopes to start this week's Olympics. But according to the University of Delaware's Dr. Karin Silbernagel, the injury likely contributed to her inability to land safely Sunday on the downhill course in Cortina d’Ampezzo, Italy. The crash ended her heroic return to competition Dr. Silbernagel, a professor of physical therapy, studies tendon injuries in the ankle and knee in elite athletes, especially Achilles ruptures and ankle function. She was quoted in an ESPN story about the rash of such injuries in the NBA and can specifically address the impact they could have on competition now and for the rest of an athlete's career. Her research shows that even after successful surgery, many athletes return to competition but not many among them return to peak explosiveness or durability. The impact a major injury would have on a fresh injury like Vonn's is obvious, she said. Dr. Silbernagel's research on ankle and knee injuries dates back to the early 2000s. She consults with professional sports teams relating to tendon injuries and is a consultant to the NFL's Musculoskeletal Committee. To connect directly with Dr. Silbernagel and arrange an interview, visit her profile and click the "contact" button. Interested members of the media can also send an email to MediaRelatons@udel.edu.

Suburbia’s ICE Shift

Lawrence Levy, associate vice president and executive dean of the National Center for Suburban Studies, is featured in the Politico report “Suburbia’s ICE Shift,” about voters – particularly those in suburban counties – souring on President Donald Trump’s aggressive deportation campaign. This is significant because the suburbs are a key indicator of how the national mood has dramatically shifted over the last month.

New study suggests Florida Chagas disease transmission

Researchers from the University of Florida Emerging Pathogens Institute and Texas A&M University gathered their resources to investigate the potential of vector-borne transmission of Chagas in Florida. The 10-year-long study, published in the Public Library of Science Neglected Tropical Diseases, used data from Florida-based submissions, as well as field evidence collected from 23 counties across Florida. Chagas disease is considered rare in the United States. Since it is not notifiable to most state health departments, it is quite difficult to know exactly how many cases there are and how frequently it’s transmitted. Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. Nuisance blood-sucking insects known as kissing bugs spread the parasite to humans when exposure to their feces penetrates the mucus membranes, breaches the skin or gets orally ingested. Interestingly, it is believed that most companion animals, like dogs and cats, acquire the parasite from eating the kissing bug itself. The first record of kissing bugs, scientifically known as Triatoma sanguisuga, harboring T. cruzi in Florida was from an insect in Gainesville in 1988. However, kissing bugs have been calling the state home for far longer than humans have. Currently, there are two known endemic species of kissing bugs in the Sunshine State: Triatoma sanguisuga, the species invading homes, and the cryptic species Paratriatoma lecticularia, which live primarily in certain Floridan ecosystems but were not found in this study. Read more ...